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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNL
RDWLRVVANSKESYELRYFQI

The query sequence (length=101) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v6x:CU 112 101 1.0000 0.9018 1.0000 2.15e-72 7a01:82, 8a3d:O, 5aj0:AU, 8b5l:U, 8b6c:U, 9bdl:AL22, 9bdn:AL22, 9bdp:AL22, 7bhp:LU, 8bhf:H1, 8bpo:T2, 8btk:BU, 7cpu:LU, 7cpv:LU, 4d5y:U, 4d67:U, 6d90:U, 6d9j:U, 9f1b:BU, 9f1c:BU, 9f1d:BU, 7f5s:LU, 8fkz:LF, 8fl2:LF, 8fl3:LF, 8fl4:LF, 8fl6:LF, 8fl7:LF, 8fl9:LF, 8fla:LF, 8flb:LF, 8flc:LF, 8fld:LF, 8fle:LF, 8flf:LF, 9fq0:LU, 6frk:U, 6ftg:U, 6fti:U, 6ftj:U, 8g5y:LU, 8g5z:LU, 8g60:LU, 8g61:LU, 8g6j:LU, 8glp:LU, 6gz3:AU, 6gz4:AU, 6gz5:AU, 6hcf:U3, 6hcj:U3, 6hcm:U3, 6hcq:U3, 8idt:d, 8idy:d, 8ie3:d, 8ifd:2O, 8ife:2O, 8ine:d, 8inf:d, 8ink:d, 6ip5:2O, 6ip6:2O, 6ip8:2O, 8ipd:d, 8ipx:d, 8ipy:d, 8ir1:d, 8ir3:d, 3j7o:U, 3j7p:U, 3j7q:U, 3j7r:U, 3j92:U, 3jag:U, 3jah:U, 3jai:U, 3jaj:U, 3jan:U, 8jdj:Z, 8jdk:Z, 8jdl:Z, 8jdm:Z, 8k2c:LU, 5lks:LU, 6lqm:d, 6lsr:d, 6lss:d, 7ls1:O2, 7ls2:O2, 6lu8:d, 5lzs:U, 5lzt:U, 5lzu:U, 5lzv:U, 5lzw:U, 5lzx:U, 5lzy:U, 5lzz:U, 7mdz:U, 6mtb:U, 6mtc:U, 6mtd:U, 6mte:U, 7nfx:U, 7nwg:U3, 7nwh:U, 7nwi:U, 7o7y:BU, 7o7z:BU, 7o80:BU, 7o81:BU, 7obr:U, 8ohd:LU, 8oj0:LU, 8oj5:LU, 8oj8:LU, 6ole:V, 6olf:V, 6olg:AU, 6oli:V, 6olz:AU, 6om0:V, 6om7:V, 7oya:U1, 7oyb:U1, 7oyc:U1, 7oyd:U, 8p2k:BU, 6p5i:AU, 6p5j:AU, 6p5k:AU, 6p5n:AU, 8q7z:BU, 8q87:BU, 8qfd:U, 7qgg:V, 8qoi:LU, 7qvp:LU, 7qvp:MU, 7qwq:U, 7qwr:U, 7qws:U, 6qzp:LU, 6r5q:U, 6r6g:U, 6r6p:U, 6r7q:U, 8rjb:U, 8rjc:U, 8rjd:U, 8scb:U, 6sgc:U2, 6swa:S, 5t2c:O, 6t59:U3, 7tm3:U, 7toq:AL22, 7tor:AL22, 7tut:U, 7ucj:U, 7uck:U, 4ug0:LU, 4ujc:BU, 4ujd:AU, 4uje:CU, 6w6l:V, 6xa1:LU, 7xnx:LU, 7xny:LU, 8xsx:LU, 8xsy:LU, 8xsz:LU, 6y0g:LU, 8y0w:LU, 8y0x:LU, 6y2l:LU, 6y57:LU, 6y6x:LU, 8yoo:LU, 8yop:LU, 6z6l:LU, 6z6m:LU, 6z6n:LU, 7zjw:LX, 7zjx:LX, 6zm7:LU, 6zme:LU, 6zmi:LU, 6zmo:LU, 6zvk:82
2 9bh5:CU 100 97 0.6238 0.6300 0.6495 2.43e-43 9cai:CU
3 8esq:U 98 96 0.5446 0.5612 0.5729 4.19e-35 8esr:U, 8etc:U, 8etg:U, 8eug:U, 8eui:U
4 4v6w:CU 116 99 0.6634 0.5776 0.6768 1.36e-34 6xu8:CU
5 8bf9:U 84 99 0.8119 0.9762 0.8283 1.63e-34
6 3j79:X 97 98 0.4851 0.5052 0.5000 2.14e-32 3jbn:AX, 3jbo:AX, 3jbp:AX, 8tpu:AX, 5umd:X
7 7qiw:W 101 99 0.6436 0.6436 0.6566 1.86e-31 8azw:K, 8b2l:K3, 7qiz:W
8 4v3p:LW 108 102 0.6634 0.6204 0.6569 1.12e-30 8ip8:ZA, 8ipa:ZA, 8ipb:ZA, 8jiv:CU, 4v7e:CU
9 8i9x:LU 105 98 0.4851 0.4667 0.5000 2.19e-30 8i9y:LU, 8i9z:LU, 8ia0:LU, 7olc:LU, 7old:LU, 8oo0:LU, 8pv1:LU, 8pv2:LU, 8pv3:LU, 8pv4:LU, 8pv5:LU, 8pv6:LU, 8pv7:LU, 8pv8:LU, 8pvk:LU, 8pvl:LU, 7z3n:LU, 7z3o:LU
10 7r81:W1 101 96 0.4653 0.4653 0.4896 1.45e-29
11 6xu6:CU 96 97 0.4752 0.5000 0.4948 3.46e-28 6xu7:CU
12 5xxb:T 99 98 0.5743 0.5859 0.5918 4.97e-27
13 8ova:BV 122 98 0.4059 0.3361 0.4184 3.53e-26 8ove:BV, 4v8m:BV
14 8rxh:LU 122 98 0.4158 0.3443 0.4286 1.17e-25 8a3w:U, 8a98:U, 6az3:U, 3jcs:U, 8rxx:LU, 5t2a:T
15 5t5h:V 85 95 0.4059 0.4824 0.4316 4.27e-23
16 4v8p:AM 100 97 0.5347 0.5400 0.5567 1.57e-22 4v8p:DM, 4v8p:FM, 4v8p:HM
17 8ovj:U 107 95 0.3762 0.3551 0.4000 1.05e-20
18 6zj3:Lj 101 101 0.4950 0.4950 0.4950 1.68e-19
19 8p5d:LU0 100 99 0.3762 0.3800 0.3838 8.19e-19 8p60:LU0, 8p60:KU0, 7qca:LU0
20 5xy3:U 97 93 0.3564 0.3711 0.3871 3.19e-18
21 8hfr:UF 115 97 0.4554 0.4000 0.4742 5.10e-18 8aaf:H, 8agt:H, 8agu:H, 8agv:H, 8agw:H, 8agx:H, 8agz:H, 5apn:U, 5apo:U, 7azy:w, 7b7d:Lq, 8bip:LU, 8bjq:LU, 8bn3:N2, 8bqd:BL, 8bqx:BL, 7bt6:U, 7btb:U, 8ccs:G, 8cdl:G, 8cdr:G, 8ceh:G, 8cf5:G, 8cg8:G, 8cgn:G, 8civ:G, 8cku:G, 8cmj:G, 5dat:N2, 5dat:n2, 5dc3:N2, 5dc3:n2, 5dge:N2, 5dge:n2, 5dgf:N2, 5dgf:n2, 5dgv:N2, 5dgv:n2, 6elz:U, 6em5:U, 8eub:AU, 8evp:AU, 8evq:AU, 8evr:AU, 8evs:AU, 8evt:AU, 8ewb:AU, 8ewc:AU, 5fci:N2, 5fci:n2, 5fcj:N2, 5fcj:n2, 6ft6:U, 5gak:W, 6gq1:U, 6gqb:U, 6gqv:U, 5h4p:U, 6hd7:W, 6hhq:5, 6hhq:CW, 5i4l:N2, 5i4l:n2, 6i7o:BL, 6i7o:YL, 5it7:UU, 3j6x:62, 3j6y:62, 3j77:72, 3j78:72, 3jct:U, 5juo:Z, 5jup:Z, 5jus:Z, 5jut:Z, 5juu:Z, 8k2d:LU, 8k82:LU, 5lyb:N2, 5lyb:n2, 5m1j:U5, 6m62:U, 5mc6:BL, 5mei:5, 5mei:CW, 7mpi:AU, 7mpj:AU, 6n8j:U, 6n8k:U, 6n8l:U, 6n8m:h, 6n8n:h, 6n8o:h, 7n8b:AU, 7nac:U, 7nad:U, 5ndg:N2, 5ndg:n2, 5ndv:N2, 5ndv:n2, 5ndw:N2, 5ndw:n2, 7nrc:LW, 7nrd:LW, 5obm:N2, 5obm:n2, 7of1:U, 7oh3:U, 7ohq:U, 7ohr:U, 7ohv:U, 6oig:U, 5on6:5, 5on6:CW, 7osa:eL22, 7osm:eL22, 8p8m:QU, 8p8n:QU, 8p8u:QU, 8pfr:QU, 6q8y:BL, 6qik:V, 6qt0:V, 6qtz:V, 7r72:U, 7r7a:U, 6r84:W, 6r86:W, 6r87:W, 6ri5:V, 7rr5:LU, 6rzz:V, 6s05:V, 6s47:AW, 6snt:au, 6sv4:BL, 6sv4:YL, 6sv4:ZL, 6t4q:LU, 5t62:h, 5t6r:h, 6t7i:LU, 6t7t:LU, 6t83:Uy, 6t83:F, 5tbw:5, 5tbw:CW, 6tb3:BL, 5tga:N2, 5tga:n2, 5tgm:N2, 5tgm:n2, 6tnu:BL, 7too:AL22, 7top:AL22, 7u0h:U, 4u3m:N2, 4u3m:n2, 4u3n:N2, 4u3n:n2, 4u3u:N2, 4u3u:n2, 4u4n:N2, 4u4n:n2, 4u4o:N2, 4u4o:n2, 4u4q:N2, 4u4q:n2, 4u4r:N2, 4u4r:n2, 4u4u:N2, 4u4u:n2, 4u4y:N2, 4u4y:n2, 4u4z:N2, 4u4z:n2, 4u50:N2, 4u50:n2, 4u51:N2, 4u51:n2, 4u52:N2, 4u52:n2, 4u53:N2, 4u53:n2, 4u55:N2, 4u55:n2, 4u56:N2, 4u56:n2, 4u6f:N2, 4u6f:n2, 7ug6:U, 7uoo:U, 7uqb:U, 7uqz:U, 6uz7:AU, 7v08:U, 4v6i:BW, 4v88:BU, 4v88:DU, 4v8t:U, 4v8y:BU, 4v8z:BU, 8v87:U, 4v91:U, 6woo:U, 6xiq:U, 6xir:U, 8y0u:LU, 6ylg:U, 6ylh:U, 6ylx:U, 6yly:U, 7z34:U, 6z6j:LU, 6z6k:LU, 7zpq:BT, 7zrs:BT, 7zs5:BV, 7zuw:BT, 7zux:ET, 7zw0:LX
22 6zu5:LU0 97 95 0.3762 0.3918 0.4000 1.55e-13
23 8c3a:5 103 100 0.4158 0.4078 0.4200 1.58e-11 8c3a:BP, 8cq7:5, 8cq7:BP, 8cqw:5, 8cqw:BP, 8cre:5, 8cre:BP, 8oeq:5, 8oeq:BP, 7pzy:5, 7q08:5, 7q0f:5, 7q0p:5, 7q0r:5, 8q5i:5
24 6rm3:LU0 97 100 0.2772 0.2887 0.2800 2.54e-08
25 8btd:LV 115 99 0.2673 0.2348 0.2727 4.39e-08 8br8:LV, 8brm:LV, 8bsi:LV, 8bsj:LV, 8btr:LV, 8fru:U, 7pwg:U, 7pwo:U2
26 7qep:N2 93 101 0.2772 0.3011 0.2772 2.46e-06
27 3m83:A 325 45 0.1782 0.0554 0.4000 2.1 5jib:A, 5jib:B, 5jib:C, 5jib:D, 5jib:E, 5jib:F, 3m81:A, 3m81:C, 3m81:B, 3m81:D, 3m81:E, 3m81:F, 3m82:A, 3m82:C, 3m82:B, 3m82:D, 3m82:E, 3m82:F, 3m83:B, 3m83:C, 3m83:D, 3m83:E, 3m83:F
28 3mpg:A 426 51 0.1485 0.0352 0.2941 2.7 3mpg:B, 4yiw:A, 4yiw:B
29 3s2z:A 251 50 0.1485 0.0598 0.3000 3.2 3pfb:A, 3pfb:B, 3pfc:A, 3qm1:A, 3s2z:B
30 7r21:T 304 49 0.1683 0.0559 0.3469 3.5 7tr6:O, 7tr8:O, 7tr9:O, 7tra:N
31 6mv2:A 356 56 0.1188 0.0337 0.2143 4.6 6mv1:A
32 7dqx:D 770 30 0.1089 0.0143 0.3667 5.6 7dqx:A
33 6m8t:A 189 50 0.1188 0.0635 0.2400 6.2 6m8u:A
34 3nzp:B 591 43 0.1584 0.0271 0.3721 6.6 3nzp:A
35 5wvu:A 510 19 0.0990 0.0196 0.5263 6.9 5wvu:B, 5wvu:C
36 7ogp:D 510 43 0.1386 0.0275 0.3256 7.7
37 7r21:J 336 52 0.1683 0.0506 0.3269 7.7 7r21:I, 7r21:K, 7r21:L, 7r21:M, 7r21:N, 7r21:O, 7r21:Q, 7r21:S, 7r2k:K, 7r2k:L, 7r2k:M, 7r2k:N, 7r2k:O, 7r2k:P, 7r2k:R, 7r2k:T, 7r2k:V, 7tr6:I, 7tr6:J, 7tr6:K, 7tr6:L, 7tr6:M, 7tr6:N, 7tr8:I, 7tr8:J, 7tr8:K, 7tr8:L, 7tr8:M, 7tr8:N, 7tr9:I, 7tr9:J, 7tr9:K, 7tr9:L, 7tr9:M, 7tr9:N, 7tra:H, 7tra:I, 7tra:J, 7tra:K, 7tra:L, 7tra:M
38 8xkf:C 377 35 0.0990 0.0265 0.2857 7.8 8xhu:A, 8xhu:B, 8xhu:C, 8xkf:A, 8xkf:B, 8xkf:D, 8xkf:F, 8xkf:E
39 6xi2:A 528 25 0.0891 0.0170 0.3600 8.0 7e9j:A, 7e9j:B, 7e9k:A, 7e9k:B, 7e9k:D, 7e9k:E, 7e9l:A, 7e9l:B, 8kb7:A, 8kb7:B, 8kb7:C, 8kb7:D, 6xfi:A, 6xi2:D
40 6dcq:M 135 58 0.1980 0.1481 0.3448 8.3 6dcq:H, 5fuu:M, 5fuu:H, 6mar:H, 6mar:M, 6olp:G, 6olp:H, 6vpx:P
41 4koa:A 333 73 0.1881 0.0571 0.2603 8.4
42 8que:D 654 53 0.1584 0.0245 0.3019 8.8 7ogr:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218