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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QVKVVVDRDVVPTSFEKWAKPGHFSRSLAKGPKTTTWIWNLHADAHDFDSHTSSLEEVSRKIFSAHFGQLAIIFIWLSGM
YFHGARFSNYVAWLSNPTGIKPSAQVVWPIVGQQILNADVGGGMQGIQITSGLFQLWRASGIVNELQLYVTALGGLGMAG
LMIFAGWFHYHKAAPKLEWFQNVESMLNHHLAGLLGLGSLSWAGHQIHVSLPINKLLDAGVAPSSIPLPHEFILNRNLMA
ELYPSFQQGLVPFFTLNWKQYSDILTFKGGLSPVTGGLWLTDVAHHHLAIAVLFLVAGHMYRTNWGIGHSIKQILEAHKG
PLTGEGHKGLYEILTTSWHANLAINLAMLGSLSIIVAHHMYAMPPYPYLATDYPTQLSLFTHHMWIGGFCIVGAGAHAAI
YMVRDYSPTVNFNNVLDRMIRHRDAIISHLNWVCIFLGMHSFGLYIHNDTMRALGRAQDMFSDTAIQLQPVFAQWIQQIH
TLAPGNTAVNALATASYAFGADTVTVGSKIAMMPIKLGTADFMVHHIHAFTIHVTTLILLKGVLYARNSRLIPDKANLGF
RFPCDGPGRGGTCQVSAWDHVFLGLFWMYNALSIVIFHFSWKMQSDVWGTVTSNGAISHITGGNFAQSAITINGWLRDFL
WAQASQVIQSYGSSLSAYGLMFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIAPRALSITQGRAVGVAH
YLLGGIATTWAFFLARIIAVG

The query sequence (length=741) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7blz:A 743 741 1.0000 0.9973 1.0000 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
2 7y5e:AN 745 741 0.8812 0.8765 0.8812 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
3 8wm6:A 742 741 0.8529 0.8518 0.8529 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
4 7dr0:A 739 739 0.8381 0.8403 0.8403 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
5 6tra:A 746 745 0.8529 0.8472 0.8483 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
6 7yca:A 742 740 0.8462 0.8450 0.8473 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
7 5l8r:A 743 742 0.8327 0.8304 0.8315 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
8 6ly5:a 742 740 0.8192 0.8181 0.8203 0.0 6l4u:A
9 6igz:A 740 741 0.8435 0.8446 0.8435 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
10 6k61:A 742 741 0.8205 0.8194 0.8205 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
11 5oy0:A 751 741 0.8327 0.8216 0.8327 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
12 6kif:A 751 752 0.8300 0.8189 0.8178 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
13 7qco:A 728 728 0.8151 0.8297 0.8297 0.0 7qco:E, 7qco:e, 7qco:a
14 6kmw:aA 721 721 0.7868 0.8086 0.8086 0.0 6kmw:bA, 6kmw:cA
15 7s3d:A 749 745 0.7692 0.7610 0.7651 0.0 7s3d:G, 7s3d:a
16 7lx0:G 751 753 0.7827 0.7723 0.7703 0.0 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
17 7dwq:A 726 724 0.7220 0.7369 0.7390 0.0
18 6kmx:aA 717 717 0.7152 0.7392 0.7392 0.0 6kmx:bA, 6kmx:cA
19 7f4v:aA 772 774 0.7341 0.7047 0.7028 0.0 7f4v:bA, 7f4v:cA
20 7coy:aA 685 713 0.6910 0.7474 0.7181 0.0 7coy:bA, 7coy:cA
21 8jjr:a 665 727 0.4831 0.5383 0.4924 0.0
22 8jze:a 670 728 0.4615 0.5104 0.4698 0.0 8jzf:a
23 8jw0:a 645 712 0.4777 0.5488 0.4972 0.0
24 7f4v:aB 725 747 0.4656 0.4759 0.4618 0.0 7f4v:bB, 7f4v:cB
25 7blz:B 731 751 0.4575 0.4637 0.4514 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
26 6kmw:aB 740 763 0.4629 0.4635 0.4495 0.0 6kmw:cB, 6kmw:bB
27 6vpv:B 737 759 0.4548 0.4573 0.4440 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
28 7y5e:BN 732 753 0.4507 0.4563 0.4436 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
29 7yca:B 732 753 0.4467 0.4522 0.4396 0.0
30 8wm6:B 732 760 0.4534 0.4590 0.4421 0.0 8wmj:B, 8wmv:B, 8wmw:B
31 6kif:B 733 755 0.4534 0.4584 0.4450 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
32 6ly5:b 732 752 0.4399 0.4454 0.4335 0.0 6l4u:B
33 7d0j:B 734 753 0.4453 0.4496 0.4382 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
34 6igz:B 733 753 0.4480 0.4529 0.4409 0.0
35 7wfd:AB 734 753 0.4480 0.4523 0.4409 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
36 7s3d:B 742 762 0.4359 0.4353 0.4239 0.0 7s3d:H, 7s3d:b
37 7fix:B1 740 767 0.4534 0.4541 0.4381 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
38 6kmx:aB 727 753 0.4345 0.4429 0.4276 0.0 6kmx:bB, 6kmx:cB
39 7qco:B 734 759 0.4413 0.4455 0.4308 0.0 7qco:G, 7qco:g, 7qco:b
40 7lx0:H 739 762 0.4345 0.4357 0.4226 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
41 6k61:B 740 763 0.4426 0.4432 0.4299 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
42 6lu1:B 713 760 0.4372 0.4544 0.4263 0.0
43 7dr0:B 706 755 0.4265 0.4476 0.4185 5.42e-179 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
44 7dwq:B 659 749 0.3968 0.4461 0.3925 1.22e-166 7coy:aB, 7coy:bB, 7coy:cB
45 8jw0:b 617 710 0.2969 0.3566 0.3099 4.63e-96
46 8jjr:b 659 728 0.3117 0.3505 0.3173 6.36e-94
47 8jze:b 663 718 0.3144 0.3514 0.3245 1.32e-92 8jzf:b
48 7zq9:B2 180 192 0.0877 0.3611 0.3385 6.41e-16
49 5v8k:A 600 232 0.0864 0.1067 0.2759 3.67e-13
50 6m32:A 628 81 0.0337 0.0398 0.3086 0.008 6m32:a
51 8gwa:A 667 79 0.0364 0.0405 0.3418 0.009 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
52 7vzg:a 858 120 0.0405 0.0350 0.2500 0.023 7vzg:A, 7vzr:A, 7vzr:a
53 8abs:A 394 63 0.0283 0.0533 0.3333 0.35 8abr:A, 5ofq:A, 5ofq:B, 5ofq:C, 5ofq:D
54 7xg0:D 331 95 0.0324 0.0725 0.2526 1.1 7xfz:C, 7xg0:C, 7xg0:E, 7xg0:F, 7xg1:C, 7xg1:D, 7xg1:E, 7xg2:C, 7xg2:D, 7xg2:E, 7xg2:F, 7xg3:C, 7xg3:D, 7xg3:E, 7xg3:F, 7xg4:C, 7xg4:D, 7xg4:E, 7xg4:F
55 8aw5:A 266 50 0.0256 0.0714 0.3800 5.7 8aw5:B, 8aw5:C
56 3bn1:A 368 28 0.0202 0.0408 0.5357 5.9 3bn1:B, 3dr4:A, 3dr4:B, 3dr4:C, 3dr4:D, 3dr7:A, 3dr7:B, 3dr7:C, 3dr7:D
57 1jqg:A 409 60 0.0243 0.0440 0.3000 8.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218