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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QVIPAPRVQVTQPYAGQKPGTSGLRKKVSEATQPNYLENFVQSIFNTLRKDELKPKNVLFVGGDGRYFNRQAIFSIIRLA
YANDISEVHVGQAGLMSTPASSHYIRKVNEEVGNCIGGIILTASHNPGGKEHGDFGIKFNVRTGAPAPEDFTDQIYTHTT
KIKEYLTVDYEFEKHINLDQIGVYKFEGTRLEKSHFEVKVVDTVQDYTQLMQKLFDFDLLKGLFSNKDFSFRFDGMHGVA
GPYAKHIFGTLLGCSKESLLNCDPSEDFGGGHPDPNLTYAHDLVELLDIHKKKDVGTVPQFGAACDGDADRNMILGRQFF
VTPSDSLAVIAANANLIFKNGLLGAARSMPTSGALDKVAAKNGIKLFETPTGWKFFGNLMDAGLINLCGEESFGTGSNHI
REKDGIWAVLAWLTILAHKNKNTDHFVTVEEIVTQYWQQFGRNYYSRYDYEQVDSAGANKMMEHLKTKFQYFEQLKQGNK
ADIYDYVDPVDQSVSKNQGVRFVFGDGSRIIFRLSGTGSVGATIRIYFEQFEQQQIQHETATALANIIKLGLEISDIAQF
TGRNEPTVIT

The query sequence (length=570) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1kfq:A 571 570 1.0000 0.9982 1.0000 0.0 1kfi:A, 1kfi:B, 1kfq:B
2 6sno:A 573 588 0.5281 0.5253 0.5119 0.0 1c47:A, 1c4g:A, 5epc:A, 5epc:B, 5f9c:A, 5jn5:A, 5jn5:B, 3pmg:A, 3pmg:B, 7s0w:A, 6snp:A, 6snq:A, 5tr2:A, 5tr2:B, 6uiq:B, 6uiq:A, 6uo6:A, 6uo6:B, 5vbi:A, 5vbi:B, 5vec:A, 5vec:B, 5vg7:A, 5vg7:B, 5vin:A, 5vin:B
3 4qg5:A 565 572 0.4789 0.4832 0.4773 9.70e-174 4qg5:B, 4qg5:C, 4qg5:D
4 6y8y:A 572 591 0.4877 0.4860 0.4704 1.98e-170 6y8x:AA, 6y8z:A
5 7p5o:B 558 573 0.4667 0.4767 0.4642 2.93e-166 7p5o:A
6 7s0w:B 499 550 0.4632 0.5291 0.4800 1.56e-160
7 7pjc:B 553 576 0.4474 0.4611 0.4427 1.88e-156 7pjc:A
8 2fuv:A 545 575 0.2456 0.2569 0.2435 1.37e-16 2fuv:B, 3na5:A, 3na5:B, 3olp:A, 3olp:B
9 1wqa:A 455 523 0.2298 0.2879 0.2505 2.21e-14 1wqa:B, 1wqa:C, 1wqa:D
10 3uw2:A 458 86 0.0491 0.0611 0.3256 0.046
11 7ojr:A 445 385 0.1456 0.1865 0.2156 0.45 7oml:A
12 8t7c:A 1001 96 0.0368 0.0210 0.2188 1.9
13 2y7h:B 529 86 0.0456 0.0491 0.3023 2.8 2y7h:C
14 4b97:A 151 76 0.0368 0.1391 0.2763 5.1
15 3w2w:A 618 107 0.0526 0.0485 0.2804 6.3 4h4k:C, 3w2v:A
16 6et7:A 646 51 0.0298 0.0263 0.3333 8.9 6et7:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218