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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QTSEYYQEAANPIATNPALWAKVTAPQISWGSTDIRYKKEEPAPIHSAQKSMNLTAWKGEKISAQLVVWTPKVLNDLTFM
VSDLTSGSATISKENIRTGFVRYVITDELNKDGLGACGYRNSADFDSTLVADVIDHITPTLTLPANSTQGGWISVNIPQG
TKAGKYTGTVTVKADGITLSELKLNLQVKNRTLPPPSEWAFHLDLWQNPYAVSRYYNVEPFSKKHFDLMRPLMKLYADAG
GKVITASIMHKPWNGQTYDAFESMVTWLKKADGTWYFDYTVFDKWVEFMMDLGVKKQISCYSMVPWRLSFQYFDQASNSF
KFLDAKPGEVAYEEFWMNMLQDFSKHLKAKGWFDITHIAMDERPMKDMQETLKVIRKADKDFKVSLAGTYHKELLDDLND
YCITIAEKFTPEEIEARRKAGKVTTYYTCCTEPRPNTFTFSEPAEAEWLAWHSAKENLDGYLRWALNSWVKNPLQDSRFT
AWAAGDTYMIYPGARSSIRLERLTEGIQFFEKVRILKEEFEEKGNKGAIKNIDKTLKMFDESSMDKISPTTAVNKAKKVI
NRY

The query sequence (length=563) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5l7v:A 563 563 1.0000 1.0000 1.0000 0.0 5l7v:B
2 5fqg:A 583 544 0.3215 0.3105 0.3327 9.69e-96 5fqh:A, 5fr0:A
3 8k2k:A 529 520 0.2043 0.2174 0.2212 9.07e-19
4 8k2m:A 559 457 0.1812 0.1825 0.2232 9.19e-09
5 8k2h:B 563 122 0.0586 0.0586 0.2705 3.17e-04 8k2h:A, 8k2i:B, 8k2i:A
6 8k2h:B 563 61 0.0320 0.0320 0.2951 1.5 8k2h:A, 8k2i:B, 8k2i:A
7 4lej:A 355 82 0.0337 0.0535 0.2317 0.52
8 3dze:A 176 98 0.0480 0.1534 0.2755 0.63 3e2j:A, 3e2j:B, 3e2j:C, 3e3z:A, 3e4g:A
9 5gan:B 1781 92 0.0391 0.0124 0.2391 1.4 4bgd:A, 5gao:B, 5gap:B, 5nrl:B, 5zwm:D, 5zwo:D
10 2fdc:A 505 97 0.0480 0.0535 0.2784 1.4
11 6o8h:A 571 97 0.0480 0.0473 0.2784 1.5 6o8g:B, 6o8g:C
12 6o8e:A 592 97 0.0480 0.0456 0.2784 1.9 1d9z:A, 2fdc:B, 6o8e:B, 6o8f:A, 6o8f:B, 6o8g:A
13 5fzo:A 339 51 0.0284 0.0472 0.3137 2.2 5fzo:B, 2ypd:A, 2ypd:B
14 5iy6:B 1165 49 0.0373 0.0180 0.4286 2.3 8a40:B, 7b0y:B, 8b3d:B, 8b3f:B, 8bvw:B, 8byq:B, 8bz1:B, 7edx:p, 7eg7:p, 7eg8:p, 7eg9:p, 7ega:p, 7egb:p, 7egc:p, 7ena:PB, 7enc:PB, 6exv:B, 5flm:B, 8gxq:PB, 8gxs:PB, 5iy7:B, 5iy8:B, 5iy9:B, 5iya:B, 5iyb:B, 5iyc:B, 5iyd:B, 7lbm:B, 7nvr:B, 7nvs:B, 7nvt:B, 7nvu:B, 7nvy:B, 7nvz:B, 7nw0:B, 8oeu:B, 8oev:B, 8oew:B, 8of0:B, 5oik:B, 7okx:B, 7oky:B, 7ol0:B, 7oo3:B, 7oob:B, 7oop:B, 7opc:B, 7opd:B, 8p4f:B, 8s52:B, 8s54:B, 8s55:B, 8uha:B, 8uhd:B, 8uhg:B, 8ui0:B, 8uis:B, 8w8e:B, 8w8f:B, 8wak:p, 8wal:p, 8wan:p, 8wao:p, 8wap:p, 8waq:p, 8war:p, 8was:p, 8wat:p, 8wau:p, 8wav:p, 8waw:p, 8wax:p, 8way:p, 8waz:p, 8wb0:p, 7zwd:B, 7zx7:B, 7zx8:B
15 7bjv:D 240 130 0.0622 0.1458 0.2692 3.5 7bju:D, 7bjv:E, 7bjv:F, 3ixp:D, 1r1k:D, 1r20:D, 2r40:D, 4umm:G
16 8bie:A 318 48 0.0284 0.0503 0.3333 5.5 8bie:B, 8bij:A, 8bij:B
17 3rf6:B 352 70 0.0373 0.0597 0.3000 6.4 3kc2:A, 3rf6:A
18 8eew:A 766 67 0.0337 0.0248 0.2836 9.8 8eew:B, 8eff:A, 8eff:B, 8eff:C, 8eff:D, 8efr:A, 8efr:B, 8efr:C, 8efr:K, 8efr:D, 8efr:L, 8efr:E, 8efr:M, 8efr:F, 8efr:N, 8efr:G, 8efr:O, 8efr:H, 8efr:P, 8efr:I, 8efr:Q, 8efr:J, 8efr:R, 6jtg:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218