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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QSNRYANLSLREEDLIAGGKHVLCAYIMKPKAGYGYLESAAHFAAESSTGTNVEVCTTDDFTRGVDALVYEIDEANELMK
IAYPVDLFDRNIIDGRAMLASFLTLAIGNNQGMGDIEYAKIHDVYFPPCYLRLFDGPAMNIVDMWRVLERPLVDGGMVVG
TIIKPKLGLRPEPFAAACYQFWLGGDFIKNDEPQGNQVFAPLRTIMPMIADSMRRAQDETGQAKLFSANITADDPAEMYA
RGEFILETFGEFADHVAFLVDGYVAGPTAVTACRRRFPQQFLHYHRAGHGAVTSPQSKRGYTAFVHCKMSRLSGASGIHT
GTMGYGKMEGDADDKAIAYMLEQDDAQGPYFRQTWQGMKATTPIISGGMNALRLPGFFDNLGHSNVIQTSGGGAFGHKDG
GAAGAKSLRQASLAWQQGVDLLDYAKEHPELAGAFESFPKDADALYPNWREKLK

The query sequence (length=454) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7t1j:B 457 454 1.0000 0.9934 1.0000 0.0 7t1j:A, 7t1j:C, 7t1j:D, 7t1j:E, 7t1j:F, 7t1j:G, 7t1j:H, 7t1j:I, 7t1j:J, 7t1j:K, 7t1j:L
2 9rub:A 459 453 0.7753 0.7669 0.7770 0.0 2rus:A, 9rub:B
3 5hqm:A 459 454 0.7709 0.7625 0.7709 0.0 5han:A, 5han:B, 5han:C, 5han:D, 5han:E, 5han:F, 5han:G, 5han:H, 5han:I, 5han:J, 5han:K, 5han:L, 5hao:A, 5hao:B, 5hao:C, 5hao:D, 5hao:E, 5hao:F, 5hat:A, 5hat:B, 5hat:C, 5hat:D, 5hat:E, 5hat:F, 5hat:G, 5hat:H, 5hat:I, 5hat:J, 5hat:K, 5hat:L, 5hjx:A, 5hjx:B, 5hjx:C, 5hjx:D, 5hjx:E, 5hjx:F, 5hjy:A, 5hjy:B, 5hjy:C, 5hjy:D, 5hjy:E, 5hjy:F, 5hk4:A, 5hk4:B, 5hk4:C, 5hk4:D, 5hk4:E, 5hk4:F, 5hql:A, 5hql:B, 5hql:C, 5hql:D, 5hql:E, 5hql:F, 5hqm:B, 5koz:A, 5koz:B, 5koz:C, 5koz:D, 5koz:E, 5koz:F, 5koz:G, 5koz:H, 5koz:I, 5koz:J, 5koz:K, 5koz:L, 4lf1:A, 4lf1:B, 4lf1:C, 4lf1:D, 4lf1:E, 4lf1:F, 4lf2:A, 4lf2:C, 4lf2:D
4 5c2g:A 461 453 0.7137 0.7028 0.7152 0.0 5c2c:A, 5c2c:B, 5c2c:C, 5c2g:C, 5c2g:B, 5c2g:F, 5c2g:D, 5c2g:E
5 5mac:A 473 468 0.4141 0.3975 0.4017 8.44e-102 5mac:B, 5mac:D, 5mac:C, 5mac:E
6 6hun:A 428 443 0.3018 0.3201 0.3093 1.86e-56
7 3kdo:C 440 436 0.3128 0.3227 0.3257 8.98e-50 3a12:A, 3a12:B, 3a12:C, 3a12:D, 3a12:E, 3a12:F, 3a12:G, 3a12:H, 3a12:I, 3a12:J, 3a13:A, 3a13:B, 3a13:C, 3a13:D, 3a13:E, 3a13:F, 3a13:G, 3a13:H, 3a13:I, 3a13:J, 3kdn:A, 3kdn:H, 3kdn:B, 3kdn:G, 3kdn:C, 3kdn:F, 3kdn:D, 3kdn:J, 3kdn:E, 3kdn:I, 3kdo:A, 3kdo:H, 3kdo:B, 3kdo:G, 3kdo:F, 3kdo:D, 3kdo:J, 3kdo:E, 3kdo:I, 3wqp:A, 3wqp:B, 3wqp:C, 3wqp:D, 3wqp:E, 3wqp:F, 3wqp:G, 3wqp:H, 3wqp:I, 3wqp:J
8 1rbl:A 467 444 0.3326 0.3233 0.3401 8.11e-49 1rbl:B, 1rbl:C, 1rbl:D, 1rbl:E, 1rbl:F, 1rbl:G, 1rbl:H, 1rsc:A, 1rsc:B, 1rsc:C, 1rsc:D, 1rsc:E, 1rsc:F, 1rsc:G, 1rsc:H
9 8dht:A 440 437 0.2996 0.3091 0.3112 1.18e-48 8dht:B, 8dht:C, 8dht:D
10 6z1f:A 466 444 0.3370 0.3283 0.3446 1.34e-47 6z1f:B, 6z1f:C, 6z1f:D, 6z1f:E, 6z1f:F, 6z1f:G, 6z1f:H
11 8uhi:A 465 445 0.3370 0.3290 0.3438 1.79e-47 8uhi:B, 8uhi:C, 8uhi:D, 8uhi:E, 8uhi:F, 8uhi:G, 8uhi:H, 3zxw:A, 3zxw:C, 3zxw:E, 3zxw:G
12 8u66:A 448 441 0.3238 0.3281 0.3333 1.41e-46 8u66:B, 8u66:C, 8u66:D, 8u66:E, 8u66:F, 8u66:G, 8u66:H
13 7qt1:C 452 440 0.3304 0.3319 0.3409 1.75e-46 7qsv:A, 7qsv:B, 7qsv:C, 7qsv:D, 7qsv:E, 7qsv:F, 7qsv:G, 7qsv:H, 7qsx:A, 7qsx:F, 7qsx:B, 7qsx:E, 7qsx:C, 7qsx:D, 7qsx:G, 7qsx:H, 7qsy:A, 7qsy:C, 7qsy:E, 7qsy:G, 7qsz:A, 7qsz:B, 7qsz:C, 7qsz:D, 7qt1:A, 7qt1:E, 7qt1:G, 7qvi:A, 7qvi:B, 7qvi:C, 7qvi:D, 7qvi:E, 7qvi:F, 7qvi:G, 7qvi:H, 7qvi:I, 7qvi:J, 7qvi:K, 7qvi:L, 7qvi:M, 7qvi:N, 7qvi:O, 7qvi:P
14 1gk8:A 469 463 0.3238 0.3134 0.3175 4.06e-46 3axm:A, 3axm:B, 3axm:C, 3axm:D, 3axm:E, 3axm:F, 3axm:G, 3axm:H, 1gk8:C, 1gk8:E, 1gk8:G, 4hhh:A, 4hhh:B, 4hhh:C, 4hhh:D, 1ir2:A, 1ir2:E, 1ir2:B, 1ir2:F, 1ir2:C, 1ir2:G, 1ir2:D, 1ir2:H, 1ir2:S, 1ir2:W, 1ir2:T, 1ir2:X, 1ir2:U, 1ir2:Y, 1ir2:V, 1ir2:Z, 7jfo:O, 7jfo:E, 7jfo:C, 7jfo:I, 7jfo:G, 7jfo:M, 7jfo:A, 4mkv:A, 4mkv:B, 4mkv:C, 4mkv:D, 8q05:A, 1rlc:L, 1uw9:A, 1uw9:B, 1uw9:E, 1uw9:K, 1uw9:H, 1uw9:O, 1uw9:V, 1uw9:R, 1uwa:A, 1uwa:O, 1uwa:B, 1uwa:E, 1uwa:H, 1uwa:V, 1uwa:K, 1uwa:R, 1uzd:A, 1uzd:B, 1uzd:E, 1uzd:K, 1uzd:H, 1uzd:R, 1uzd:O, 1uzd:V, 1uzh:A, 1uzh:B, 1uzh:E, 1uzh:K, 1uzh:H, 1uzh:R, 1uzh:O, 1uzh:V, 2v63:A, 2v63:B, 2v63:C, 2v63:D, 2v63:E, 2v63:F, 2v63:G, 2v63:H, 2v67:A, 2v67:B, 2v67:C, 2v67:D, 2v67:E, 2v67:F, 2v67:G, 2v67:H, 2v68:A, 2v68:B, 2v68:C, 2v68:D, 2v68:E, 2v68:F, 2v68:G, 2v68:H, 2v69:A, 2v69:B, 2v69:C, 2v69:D, 2v69:E, 2v69:F, 2v69:G, 2v69:H, 2v6a:A, 2v6a:B, 2v6a:C, 2v6a:D, 2v6a:E, 2v6a:F, 2v6a:G, 2v6a:H, 2vdh:A, 2vdh:B, 2vdh:C, 2vdh:D, 2vdh:E, 2vdh:F, 2vdh:G, 2vdh:H, 2vdi:A, 2vdi:B, 2vdi:C, 2vdi:D, 2vdi:E, 2vdi:F, 2vdi:G, 2vdi:H
15 7qsw:C 467 446 0.3260 0.3169 0.3318 9.84e-46 7qsw:A, 7qsw:E, 7qsw:G
16 1iwa:A 473 447 0.3150 0.3023 0.3199 5.36e-45 1bwv:A, 1bwv:C, 1bwv:E, 1bwv:G, 4f0h:A, 1iwa:C, 1iwa:E, 1iwa:I, 1iwa:K, 1iwa:M, 1iwa:O
17 8bdb:A 480 448 0.3084 0.2917 0.3125 1.92e-44 8bdb:C, 8bdb:E, 8bdb:G, 8bdb:I, 8bdb:K, 8bdb:M, 8bdb:O
18 6ura:A 441 437 0.3172 0.3265 0.3295 6.45e-43 6ura:B, 6ura:C, 6ura:D
19 1rbo:L 467 445 0.3150 0.3062 0.3213 1.19e-41 1aa1:L, 1aa1:B, 1aa1:E, 1aa1:H, 1aus:L, 1aus:M, 1aus:N, 1aus:O, 3axk:A, 3axk:B, 1ej7:L, 1ir1:A, 1ir1:B, 1ir1:C, 1ir1:D, 5iu0:A, 5iu0:B, 8qj0:L, 8qj0:M, 8qj0:N, 8qj0:O, 1rbo:B, 1rbo:E, 1rbo:H, 1rco:L, 1rco:B, 1rco:E, 1rco:H, 1rco:K, 1rco:O, 1rco:R, 1rco:V, 1rcx:L, 1rcx:B, 1rcx:E, 1rcx:H, 1rcx:K, 1rcx:O, 1rcx:R, 1rcx:V, 4rub:A, 4rub:D, 4rub:B, 4rub:C, 8ruc:A, 8ruc:C, 8ruc:E, 8ruc:G, 1rxo:L, 1rxo:B, 1rxo:E, 1rxo:H, 1upm:B, 1upm:L, 1upm:E, 1upm:H, 1upm:K, 1upm:O, 1upm:R, 1upm:V, 1upp:A, 1upp:C, 1upp:E, 1upp:G, 1wdd:A, 1wdd:E, 5wsk:A, 5wsk:B, 5wsk:C, 5wsk:D
20 1bxn:A 445 439 0.3062 0.3124 0.3166 2.22e-41 1bxn:C, 1bxn:E, 1bxn:G
21 7smk:A 455 444 0.3040 0.3033 0.3108 8.38e-41 7snv:A
22 5nv3:A 467 466 0.3128 0.3041 0.3047 1.20e-39 5nv3:E, 5nv3:B, 5nv3:F, 5nv3:C, 5nv3:G, 5nv3:D, 5nv3:H
23 8cmy:C 445 418 0.2885 0.2944 0.3134 4.35e-39 8cmy:M, 8cmy:G, 8cmy:I, 8cmy:K, 8cmy:O, 7yyo:A, 7yyo:C, 7yyo:E, 7yyo:G, 7yyo:I, 7yyo:K, 7yyo:M, 7yyo:O
24 6ftl:A 482 441 0.3084 0.2905 0.3175 4.71e-39 6ftl:C, 6ftl:E, 6ftl:G, 5mz2:A, 5mz2:B, 5mz2:C, 5mz2:D, 5mz2:H, 5mz2:G, 5mz2:F, 5mz2:E, 5n9z:A, 5n9z:B, 5n9z:H, 5n9z:G, 5n9z:F, 5n9z:E, 5n9z:D, 5n9z:C, 5oya:A, 5oya:B, 5oya:C, 5oya:D, 5oya:E, 5oya:F, 5oya:G, 5oya:H, 7yk5:G, 7yk5:F, 7yk5:E, 7yk5:D, 7yk5:C, 7yk5:B, 7yk5:A, 7yk5:H
25 2oek:A 412 366 0.1938 0.2136 0.2404 1.48e-07 2oej:B, 2oek:B, 2oel:A, 2oel:B, 2oem:A, 2oem:B
26 4nas:B 399 378 0.2115 0.2406 0.2540 0.001 4nas:A, 4nas:C, 4nas:D
27 3vcr:A 216 53 0.0396 0.0833 0.3396 0.13 3vcr:B
28 4ydo:B 412 63 0.0485 0.0534 0.3492 3.6 4yde:B
29 2d3m:A 405 93 0.0595 0.0667 0.2903 7.2 2d3m:B, 2d52:A, 2d52:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218