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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QSMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFI
LDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGF
CTEVEEDLIDAVMGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGAT
IHALHVLESGGFRSLLINAVEASCIRTRELQSMAD

The query sequence (length=275) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8tcw:A 282 275 0.9964 0.9716 0.9964 0.0 8dkg:A, 8dkg:B, 8dkg:C, 8dkg:D, 8dkg:E, 2gr9:A, 2gr9:B, 2gr9:C, 2gr9:D, 2gr9:E, 2gra:A, 2gra:B, 2gra:C, 2gra:D, 2gra:E, 2izz:A, 2izz:B, 2izz:C, 2izz:D, 2izz:E, 8tcu:A, 8tcu:B, 8tcu:C, 8tcu:D, 8tcu:E, 8tcv:B, 8tcw:B, 8tcw:C, 8tcw:D, 8tcw:E, 8tcx:A, 8tcx:B, 8tcx:C, 8tcx:D, 8tcy:A, 8tcy:B, 8tcy:C, 8tcy:D, 8tcz:A, 8tcz:B, 8td0:A, 8td0:B, 8td0:C, 8td0:D, 8td1:A, 8td1:B, 8td1:C, 8td1:D, 8td1:E, 8td2:A, 8td2:B, 8td2:C, 8td2:D, 8td2:E, 8td3:A, 8td3:B, 8td3:C, 8td3:D, 8td3:E, 8td4:A, 8td4:B, 8td4:C, 8td4:D, 8td4:E, 8td5:A, 8td5:B, 8td5:C, 8td5:D, 8td5:E, 8td6:A, 8td6:B, 8td6:C, 8td6:D, 8td6:E, 8td7:A, 8td7:B, 8td7:C, 8td7:D, 8td7:E, 8td8:A, 8td8:B, 8td8:C, 8td8:D, 8td8:E, 8td9:A, 8td9:B, 8td9:C, 8td9:D, 8td9:E, 8tdb:A, 8tdb:B, 8tdb:C, 8tdb:D, 8tdb:E, 8tdc:A, 8tdc:B, 8tdc:C, 8tdc:D, 8tdc:E, 8tdd:A, 8tdd:B, 8tdd:C, 8tdd:D, 5uat:C, 5uat:E, 5uau:A, 5uau:B, 5uau:C, 5uau:D, 5uau:E, 5uav:A, 5uav:B, 5uav:C, 5uav:D, 5uav:E, 8vre:A, 8vre:B, 8vre:C, 8vre:D, 8vre:E, 6xoz:A, 6xoz:B, 6xoz:C, 6xoz:D, 6xoz:E, 6xp0:A, 6xp0:B, 6xp0:C, 6xp0:D, 6xp0:E, 6xp1:A, 6xp1:B, 6xp2:A, 6xp2:E, 6xp3:A, 6xp3:B, 6xp3:C, 6xp3:D
2 5bse:A 272 273 0.4145 0.4191 0.4176 2.82e-65 5bse:B, 5bse:C, 5bse:D, 5bse:E, 5bse:G, 5bse:I, 5bse:J, 5bsf:A, 5bsf:B, 5bsf:C, 5bsf:D, 5bsf:E, 5bsf:F, 5bsf:G, 5bsf:H, 5bsf:I, 5bsf:J, 5bsg:A, 5bsg:B, 5bsg:C, 5bsg:D, 5bsg:E, 5bsg:F, 5bsg:G, 5bsg:H, 5bsg:I, 5bsg:J, 5bsh:A, 5bsh:B, 5bsh:C, 5bsh:D, 5bsh:E, 5bsh:F, 5bsh:G, 5bsh:H, 5bsh:I, 5bsh:J
3 3tri:A 272 275 0.3818 0.3860 0.3818 9.12e-49 3tri:B
4 2rcy:A 262 272 0.3018 0.3168 0.3051 3.81e-47 2rcy:E, 2rcy:B, 2rcy:C, 2rcy:D
5 2ahr:E 259 272 0.2509 0.2664 0.2537 2.80e-23 2ahr:A, 2ahr:D, 2ahr:B, 2ahr:C, 2amf:D, 2amf:A, 2amf:B, 2amf:C, 2amf:E
6 2ag8:A 263 277 0.2764 0.2890 0.2744 2.23e-21
7 1i36:A 258 74 0.0873 0.0930 0.3243 0.11 1i36:B
8 3a4t:A 258 42 0.0582 0.0620 0.3810 6.4 3a4t:B
9 1nas:A 259 74 0.0691 0.0734 0.2568 7.0 1oaa:A, 1sep:A
10 9iq9:B 275 65 0.0618 0.0618 0.2615 8.3 7euk:A, 7euk:B, 7eul:A, 7eun:A, 7eun:B, 7euq:A, 7euq:B, 9iq9:A, 8ius:A, 8ius:B, 8iut:A, 8iut:B, 8iuu:A, 8iuu:B, 8iuv:A, 8iuv:B, 8iuw:A, 8iuw:B, 6lug:A, 6lug:B, 6luh:A, 6luh:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218