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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QRVKLGDIMGILNKKAVHAAEELRPVPGIRTGDIVQIRLEVPENKRRLSVYKGIVISRQNAGIHTTIRIRRIIAGVGVEI
VFPLYSPNIKEIKVVSHRKVRKARLYYLRDKLPRLSTF

The query sequence (length=118) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6eri:AP 118 118 1.0000 1.0000 1.0000 9.03e-81 5h1s:R, 5mlc:R, 5mmi:Q, 5mmm:Q, 4v61:BR, 5x8p:Q, 5x8t:Q
2 6xyw:Ap 114 103 0.5254 0.5439 0.6019 2.00e-34
3 5myj:BS 114 96 0.3475 0.3596 0.4271 2.12e-23
4 7as8:T 115 92 0.3475 0.3565 0.4457 7.62e-21 7aqc:a, 7aqd:a, 7as9:T, 8buu:P, 6ha1:P, 6ha8:P, 6htq:P, 3j3v:P, 3j3w:P, 3j9w:BS, 5njt:i, 7o5b:m, 7ope:T, 6ppf:P, 6ppk:P, 6pvk:P, 8qcq:P, 7qgu:P, 7qh4:P, 8qpp:m, 7qv1:P, 7qv2:P, 7qv3:P, 8r55:m, 8s1p:P, 8s1u:P, 7s9u:P, 7sae:P, 6tnn:i, 6tpq:i
5 7nhk:S 114 91 0.3559 0.3684 0.4615 8.37e-21 6o8w:Q, 6o8x:Q, 6o8y:Q, 6o8z:Q, 6o90:Q, 7p7q:S, 7p7r:S, 7p7s:S, 7p7t:S, 7p7u:S, 6w6p:Q, 6wu9:Q
6 6dzi:Q 113 86 0.3390 0.3540 0.4651 3.10e-20 6dzp:Q, 7f0d:P, 8fr8:C, 8kab:Q, 7kgb:P, 7msc:P, 7msh:P, 7msm:P, 7msz:P, 7mt2:P, 7mt3:P, 7mt7:P, 5o60:Q, 5o61:Q, 7s0s:R, 7sfr:P, 5v7q:P, 5v93:P, 8v9j:R, 8v9k:R, 8v9l:R, 8whx:S, 8why:S, 8wi7:S, 8wi8:S, 8wib:S, 8wic:S, 7xam:Q, 5xym:P, 8xz3:Q, 7y41:Q, 5zeb:Q, 5zep:Q, 5zet:Q
7 8uu4:R 113 91 0.3475 0.3628 0.4505 5.22e-20 8a57:S, 8a5i:S, 8a63:S, 7nhn:S, 8uu5:R, 8uu6:R, 8uu7:R, 8uu8:R, 8uu9:R, 8uua:R
8 7asm:N 114 97 0.3305 0.3421 0.4021 2.29e-19 7asn:N, 7asp:N, 6ddd:A, 6ddg:A, 6fxc:AN, 6fxc:BN, 5hkv:M, 5hl7:M, 6hma:N, 5li0:S, 5nd8:S, 5nd9:S, 5ngm:AN, 7nhl:S, 7nhm:S, 5nrg:M, 8p2f:S, 8p2g:S, 8p2h:S, 7p48:N, 6s0x:N, 6s0z:N, 6s12:N, 6s13:N, 6sj6:S, 5t7v:L1, 5tcu:L1, 7ttu:A, 7ttw:A, 4wce:M, 4wf9:M, 4wfa:M, 4wfb:M, 6wqn:A, 6wqq:A, 6wrs:A, 6wru:A, 8y36:N, 8y37:N, 8y38:N, 8y39:N, 6yef:S
9 9c4g:o 114 85 0.3305 0.3421 0.4588 2.76e-19 8crx:o, 8cvm:o
10 8fmw:AR 117 86 0.3220 0.3248 0.4419 3.70e-19 8fn2:R
11 8a3l:o 114 89 0.3220 0.3333 0.4270 2.12e-18 7abz:P, 7ac7:P, 7acj:P, 7acr:P, 5ady:P, 5afi:P, 5aka:P, 8akn:o, 8am9:o, 8ana:o, 8ap4:o, 9ax7:o, 9ax8:P, 8aye:o, 8b0x:o, 7b5k:P, 8b7y:X, 3bbx:P, 8bf7:M, 8bge:M, 8bgh:M, 8bh4:M, 8bhj:M, 8bhl:M, 8bhn:M, 8bhp:M, 8bil:M, 8bim:M, 7bl2:P, 7bl3:P, 7bl4:P, 7bl5:P, 7bl6:P, 6bu8:18, 7bv8:Q, 6by1:CP, 6by1:DP, 6c4i:Q, 8c8x:P, 8c8y:P, 8c8z:P, 8c90:P, 8c91:P, 8c92:P, 8c93:P, 8c94:P, 8c96:P, 8c97:P, 8cam:o, 8ceu:o, 8cgd:o, 8cgk:o, 8cgv:o, 9cg5:o, 9cg6:o, 9cg7:o, 7cpj:P, 4csu:P, 7d6z:P, 7d80:o, 6dnc:T, 8eiu:o, 8ekc:R, 8emm:o, 6enf:P, 6enj:P, 6enu:P, 9fbv:o, 8fiz:BW, 8fto:o, 8fzd:R, 8fze:R, 8fzf:R, 8fzg:R, 8fzh:R, 8fzi:R, 8fzj:R, 8g2u:P, 8g31:P, 8g34:P, 8g38:P, 8g6w:o, 8g6x:o, 8g6y:o, 8g7p:R, 8g7q:R, 8g7r:R, 8g7s:R, 5gad:Q, 5gae:Q, 5gaf:Q, 5gag:Q, 5gah:Q, 6gbz:P, 6gc0:P, 6gc4:P, 6gc6:P, 6gc7:P, 6gc8:P, 6gwt:P, 6gxm:P, 6gxn:P, 6gxo:P, 6gxp:P, 6h4n:P, 5h5u:Q, 6h58:P, 6h58:PP, 6hrm:P, 8hsp:o, 8htz:o, 8hu1:o, 6i0y:P, 6i7v:DQ, 6i7v:CQ, 8ifb:o, 8ifc:o, 5iqr:P, 5it8:DQ, 5it8:CQ, 8j1z:o, 2j28:P, 3j5l:P, 5j5b:DQ, 5j5b:CQ, 3j7z:P, 5j7l:DQ, 5j7l:CQ, 3j8g:P, 5j88:DQ, 5j88:CQ, 5j8a:DQ, 5j8a:CQ, 3j9y:P, 3j9z:LM, 5j91:DQ, 5j91:CQ, 3ja1:LR, 3jbu:p, 3jbv:p, 3jcd:P, 3jce:P, 3jcj:O, 3jcn:P, 5jc9:DQ, 5jc9:CQ, 7jss:p, 7jsw:p, 7jsz:p, 5jte:BP, 7jt1:p, 7jt2:p, 7jt3:p, 5ju8:BP, 7k00:o, 7k50:p, 7k51:p, 7k52:p, 7k53:p, 7k54:p, 7k55:p, 5kcr:1T, 5kcs:1T, 8kie:o, 5kps:P, 5kpv:O, 5kpw:O, 5kpx:O, 5l3p:T, 6lkq:6, 7lv0:p, 7lvk:X, 5lza:P, 5lzb:P, 5lzc:P, 5lzd:P, 5lze:P, 5lzf:P, 7m5d:P, 5mdv:P, 5mdw:P, 5mdy:P, 5mdz:P, 5mgp:P, 7n1p:LS, 7n2c:LS, 7n2u:LS, 7n2v:LS, 7n30:LS, 7n31:LS, 7nbu:o, 5nco:Q, 5np6:n, 7nso:P, 7nsp:P, 7nsq:P, 5nwy:c, 7nwt:P, 7nww:O, 7o19:BP, 7o1a:BP, 7o1c:BP, 5o2r:P, 6o9j:P, 6o9k:P, 7ode:X, 6ofx:p, 6og7:p, 6ogf:p, 6ogg:p, 6ogi:p, 7oif:O, 7oig:O, 7oii:O, 7oiz:o, 7oj0:o, 6om6:P, 6ore:P, 6orl:P, 6osk:P, 6osq:P, 6ost:P, 6ot3:P, 7ot5:O, 7otc:P, 6ouo:P, 8p16:P, 8p17:P, 8p18:P, 7p3k:o, 8peg:s, 8phj:o, 6pj6:X, 7pjs:P, 7pjt:P, 7pju:P, 7pjv:P, 7pjw:P, 7pjx:P, 7pjy:P, 7pjz:P, 8pkl:s, 8pva:o, 7q4k:BP, 8q4f:o, 6q97:P, 6q98:P, 6q9a:P, 8qbt:P, 6qdw:p, 7qg8:c, 7qgh:c, 7qgn:c, 7qgr:c, 8qk7:P, 8qoa:o, 7qq3:X, 6qul:Q, 8r6c:o, 8r8m:o, 8rpy:P, 8rpz:P, 8rq0:P, 8rq2:P, 6s0k:Q, 7s1g:X, 7s1h:X, 7s1i:X, 7s1j:X, 7s1k:X, 7sa4:P, 7ss9:p, 7ssd:p, 7ssl:p, 7ssn:p, 7sso:p, 7ssw:p, 7st2:p, 7st6:p, 7st7:p, 8syl:R, 6szs:P, 8t5d:P, 8t5h:P, 6tbv:L191, 6tc3:L191, 7tos:L19, 4u1u:BP, 4u1u:DP, 4u1v:BP, 4u1v:DP, 4u20:BP, 4u20:DP, 4u24:BP, 4u24:DP, 4u25:BP, 4u25:DP, 4u26:BP, 4u26:DP, 4u27:BP, 4u27:DP, 5u4i:Q, 6u48:CQ, 5u9f:18, 5u9g:18, 7ug7:LS, 7uph:o, 8upo:y, 8upr:y, 8uql:y, 8uqm:y, 8uqp:y, 8ur0:y, 8urh:y, 8uri:y, 8urx:y, 8ury:y, 4uy8:P, 5uyk:18, 5uyl:18, 5uym:18, 5uyn:18, 5uyp:18, 5uyq:18, 4v4h:BP, 4v4h:DP, 4v4q:BP, 4v4q:DP, 4v4v:BN, 4v4w:BN, 4v50:BP, 4v50:DP, 4v52:BP, 4v52:DP, 4v53:BP, 4v53:DP, 4v54:BP, 4v54:DP, 4v55:BP, 4v55:DP, 4v56:BP, 4v56:DP, 4v57:BP, 4v57:DP, 4v5b:AP, 4v5b:CP, 4v5h:BP, 4v5y:BP, 4v5y:DP, 4v64:BP, 4v64:DP, 4v65:BI, 4v66:BI, 4v69:BP, 4v6c:BP, 4v6c:DP, 4v6d:BP, 4v6d:DP, 4v6e:BP, 4v6e:DP, 4v6k:AQ, 4v6l:BQ, 4v6m:BP, 4v6n:AR, 4v6o:BR, 4v6p:BR, 4v6q:BR, 4v6r:BR, 4v6s:AR, 4v6t:BP, 4v6v:BT, 4v6y:BP, 4v6z:BP, 4v70:BP, 4v71:BP, 4v72:BP, 4v73:BP, 4v74:BP, 4v75:BP, 4v76:BP, 4v77:BP, 4v78:BP, 4v79:BP, 4v7a:BP, 4v7b:BP, 4v7c:BR, 4v7d:AS, 4v7i:AP, 4v7s:BP, 4v7s:DP, 4v7t:BP, 4v7t:DP, 4v7u:BP, 4v7u:DP, 4v7v:BP, 4v7v:DP, 4v85:BT, 4v89:BT, 4v9c:BP, 4v9c:DP, 4v9d:CP, 4v9d:DP, 4v9o:AP, 4v9o:CP, 4v9o:EP, 4v9o:GP, 4v9p:AP, 4v9p:CP, 4v9p:EP, 4v9p:GP, 8vs9:L19, 8vsa:L19, 6vu3:y, 6vwl:N, 6vwm:N, 6vwn:N, 6vyq:y, 6vyr:y, 6vys:y, 6vyt:y, 6vyu:y, 6vyw:y, 6vyx:y, 6vyy:y, 6vyz:y, 6vz2:y, 6vz3:y, 6vz5:y, 6vz7:y, 6vzj:y, 8w51:Q, 5wdt:P, 6wd0:p, 6wd1:p, 6wd2:p, 6wd3:p, 6wd4:p, 6wd5:p, 6wd6:p, 6wd7:p, 6wd8:p, 6wd9:p, 6wda:p, 6wdb:p, 6wdc:p, 6wdd:p, 6wde:p, 6wdf:p, 6wdg:p, 6wdh:p, 6wdi:p, 6wdj:p, 6wdk:p, 6wdl:p, 6wdm:p, 5we4:P, 5we6:P, 4wf1:BP, 4wf1:DP, 5wf0:P, 5wfk:P, 5wfs:P, 6wnt:p, 6wnv:p, 6wnw:p, 4woi:BP, 4woi:CP, 4www:RP, 4www:YP, 6x6t:y, 6x7f:y, 6x7k:y, 6x9q:y, 6xdq:y, 6xdr:y, 6xgf:y, 6xii:y, 6xij:y, 6xz7:P, 6xza:P2, 6xzb:P2, 6y69:P, 7y7c:o, 7y7d:o, 7y7e:o, 7y7f:o, 7y7g:o, 7y7h:o, 4ybb:DQ, 4ybb:CQ, 7yla:X, 6ys3:p, 6ysr:P, 6yss:P, 6yst:P, 6ysu:P, 7z20:p, 7zod:p, 7zp8:p, 7zq5:p, 7zq6:p, 6ztj:BQ, 6ztl:BQ, 6ztm:BQ, 6ztn:BQ, 6zto:BQ, 6ztp:BQ, 7zta:L191, 6zu1:BQ
12 7uvv:O 117 97 0.3136 0.3162 0.3814 1.20e-17 7m4v:O, 7m4w:O, 7m4x:O, 7m4y:O, 7m4z:O, 7ryf:O, 7ryg:O, 7ryh:O, 7uvw:O, 7uvx:O, 7uvy:O, 7uvz:O, 7uw1:O, 6v39:O, 6v3a:O, 6v3b:O, 6v3d:O, 6yhs:L, 6ysi:L
13 8rd8:Oi 115 86 0.3136 0.3217 0.4302 1.79e-17 8rdv:Oi, 8rdw:Oi
14 6spf:P 114 96 0.3051 0.3158 0.3750 1.99e-17 8cd1:P, 6spb:P, 6spd:P, 6spg:P, 7unr:R, 7unu:R, 7unv:R, 7unw:R
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16 7pkt:n 173 109 0.2966 0.2023 0.3211 2.01e-16
17 4v4g:BQ 125 91 0.2966 0.2800 0.3846 3.71e-16 7a0r:M, 7a0s:M, 7a18:M, 3cf5:M, 3dll:M, 5dm6:M, 5dm7:M, 4io9:M, 4ioa:M, 4ioc:M, 5jvg:M, 5jvh:M, 3pio:M, 3pip:M, 4u67:M, 4v4g:DQ, 4v4g:FQ, 4v4g:HQ, 4v4g:JQ, 4wfn:M, 2zjp:M, 2zjq:M, 2zjr:M
18 6gaw:BT 240 93 0.3220 0.1583 0.4086 4.76e-16 5aj4:BT, 6gb2:BT, 7nqh:BT, 7nql:BT, 7nsh:BT, 7nsi:BT, 7nsj:BT, 8oin:BX, 8oiq:BX, 4v19:T, 6ydp:BT, 6ydw:BT
19 6vlz:Q 240 93 0.3136 0.1542 0.3978 9.27e-16 7a5f:Q3, 7a5g:Q3, 7a5h:Q, 7a5i:Q3, 7a5j:Q, 7a5k:Q3, 8any:Q, 6i9r:Q, 3j7y:Q, 3j9m:Q, 8k2a:LS, 8k2b:LS, 7l08:Q, 7l20:Q, 6nu2:Q, 6nu3:Q, 7o9k:Q, 7o9m:Q, 7odr:Q, 7ods:Q, 7odt:Q, 7of0:Q, 7of2:Q, 7of3:Q, 7of4:Q, 7of5:Q, 7of6:Q, 7of7:Q, 7og4:XQ, 7oi7:Q, 7oi8:Q, 7oi9:Q, 7oia:Q, 7oib:Q, 7oic:Q, 7oid:Q, 7oie:Q, 8oir:BX, 8oit:BX, 5ool:Q, 5oom:Q, 7pd3:Q, 8pk0:Q, 7po4:Q, 7qh6:Q, 7qh7:Q, 7qi4:Q, 7qi5:Q, 7qi6:Q, 8qsj:Q, 8qu1:Q, 8qu5:Q, 6vmi:Q, 8xt0:LS, 8xt1:LS, 8xt2:LS, 8xt3:LS, 6zm5:Q, 6zm6:Q, 6zs9:XQ, 6zsa:XQ, 6zsb:XQ, 6zsc:XQ, 6zsd:XQ, 6zse:XQ, 6zsg:XQ
20 7jil:P 112 88 0.2458 0.2589 0.3295 4.67e-14
21 8a22:An 170 97 0.1864 0.1294 0.2268 4.95e-07 8apn:An, 8apo:An
22 6ywe:M 194 84 0.1949 0.1186 0.2738 0.002 6yws:M, 6ywv:M, 6ywx:M, 6ywy:M
23 3j6b:M 151 85 0.2119 0.1656 0.2941 0.075 5mrc:M, 5mre:M, 5mrf:M
24 6ar2:A 134 47 0.1271 0.1119 0.3191 0.55 6ar2:B
25 8y9b:B 1607 31 0.1017 0.0075 0.3871 1.1
26 8qeo:A 2146 31 0.1017 0.0056 0.3871 1.1
27 6oq5:A 2346 31 0.1017 0.0051 0.3871 1.1 6oq7:A, 7s0z:B, 7s0z:A
28 8qen:A 2363 31 0.1017 0.0051 0.3871 1.1 9bja:A, 9bja:B, 2bvl:A, 2bvm:A, 6c0b:A, 7lou:A, 7lou:B, 7lov:A, 7lov:B, 3pa8:A, 3pa8:B, 3pee:B, 3pee:A, 7s0y:A, 5uqm:A, 5uqn:A, 5uqt:A, 5uqt:B
29 8tny:B 545 31 0.0763 0.0165 0.2903 2.2 8tny:A
30 8snd:A 500 55 0.1271 0.0300 0.2727 2.4 8snc:A, 8sne:A, 7sp6:A, 7sp7:A, 7sp8:A, 7sp9:A, 7spa:A
31 5e4m:A 177 33 0.0932 0.0621 0.3333 4.0 5e4b:A, 5e4b:B, 5e4m:B
32 2oaj:A 875 36 0.1271 0.0171 0.4167 4.4
33 6pbm:A 426 27 0.1102 0.0305 0.4815 4.6 6c4n:A, 6c4n:B, 6pbm:B, 6pbn:A, 6pbn:B, 6pbp:A, 6pbp:B, 6pbt:A, 6pbt:B
34 3zqj:D 921 61 0.1610 0.0206 0.3115 4.7 3zqj:B, 3zqj:E
35 8fru:L 202 20 0.0932 0.0545 0.5500 5.1 8br8:LM, 8brm:LM, 8bsi:LM, 8bsj:LM, 8btd:LM, 8btr:LM, 7pwg:L, 7pwo:L2
36 4pkm:A 305 30 0.0847 0.0328 0.3333 5.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218