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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QRRPAGKKVPFQKDSFLKQFEKLSQSRKQHVLLESARGGRYSIAGLDPIATVKGKDGITTIKHGDEMLFKEGDPLRAFHS
WFKTLETETDHELPDFQGGAIGFLSYDYARYIENFKMLSLDDLETPDIYFLVFDDIAVYDHQEESLWLITHVNGTDNSAD
VKLSELERMWLTELPAVPSDGSFAAPFTEDGFSQAVEKIKQYIASGDVFQVNLSIRQSQSLSVHPYQIYKTLREVNPSPY
MAYLETPDFQIICGSPELLVSKKGKLLETRPIAGTRSRGKTDEEDESLANELIHNEKERAEHVMLVDLERNDLGRVSRYG
SVRVNEFMAIEKYSHVMHIVSNVQGELQDGYDAVDIIHAVFPGGTITGAPKVRTMEIIEELEPTRRGLYTGSIGWFGYNH
DLQFNIVIRTIYATGGQAFMQSGAGVVIDSVPKHEYRESFKKAFAMQKALELSE

The query sequence (length=454) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7pi1:DDD 459 458 0.9581 0.9477 0.9498 0.0 7pi1:AAA, 7pi1:BBB, 7pi1:CCC, 7qu9:A, 7qu9:B, 7qu9:C
2 5cwa:A 505 476 0.4251 0.3822 0.4055 8.38e-98
3 7bvd:A 499 468 0.4163 0.3788 0.4038 1.03e-94
4 1k0e:A 437 414 0.3018 0.3135 0.3309 1.84e-76 1k0g:A
5 1k0g:B 415 413 0.2841 0.3108 0.3123 2.24e-65 1k0e:B
6 8hx8:A 673 455 0.3480 0.2348 0.3473 2.32e-63 8hx6:A, 8hx6:B, 8hx7:A, 8hx7:B, 8hx8:B, 8hx9:B
7 8hx9:A 632 456 0.3414 0.2453 0.3399 1.29e-62
8 1i1q:A 512 365 0.2819 0.2500 0.3507 1.27e-61
9 1i7q:A 517 365 0.2819 0.2476 0.3507 3.22e-59 1i7q:C, 1i7s:A, 1i7s:C
10 5jy9:B 424 190 0.1432 0.1533 0.3421 1.68e-27 2fn0:A, 2fn0:B, 2fn1:A, 2fn1:B, 5jy9:A
11 3veh:B 451 263 0.1542 0.1552 0.2662 2.74e-23 2g5f:A, 2g5f:B, 3log:B, 8qc4:A, 8qc4:B, 8qn5:A, 8qn5:B, 8qn5:C, 8qn5:D, 3rv6:A, 3rv7:A, 3rv7:B, 3rv7:C, 3rv7:D, 3rv8:A, 3rv8:B, 3rv8:C, 3rv8:D, 3rv9:A, 3rv9:B, 3rv9:D, 3st6:A, 3st6:B, 3veh:A, 3veh:C, 3veh:D, 6za4:A, 6za4:C, 6za4:D, 6za5:B, 6za5:D
12 3hwo:A 379 258 0.1476 0.1768 0.2597 1.06e-18 3hwo:B, 5jxz:A, 5jxz:B, 5jy4:A, 5jy4:B, 5jy8:A, 5jy8:B, 5jzd:A, 5jzd:B
13 3bzn:A 430 265 0.1366 0.1442 0.2340 1.30e-15
14 8w6v:A 494 277 0.1520 0.1397 0.2491 4.31e-14 8w6v:B, 8w71:A, 8w71:B
15 6za4:B 423 262 0.1344 0.1442 0.2328 1.11e-13 3rv6:B, 3rv9:C
16 3r75:B 622 236 0.1145 0.0836 0.2203 0.021 3r75:A, 3r76:A, 3r76:B
17 3to3:B 595 120 0.0727 0.0555 0.2750 3.6
18 8a5v:E 366 51 0.0396 0.0492 0.3529 5.6 8a5v:C, 8a5v:F, 8a5v:B, 8a5v:A, 8a5v:G, 8a5v:H, 8a5w:D, 8a5w:C, 8a5w:E, 8a5w:F, 8a5w:B, 8a5w:A, 8a5w:H, 3e77:A, 3e77:B
19 4e6r:A 58 18 0.0220 0.1724 0.5556 7.3
20 6k5j:A 526 91 0.0595 0.0513 0.2967 9.2
21 5j37:E 206 82 0.0441 0.0971 0.2439 9.9 5j37:B, 5j37:A, 5j37:D, 5j37:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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