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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QRIGVIGTGAIGGFYGLMLAHAGHDVHFLLRSEFEAVNRAGLSLNSAVHGFRRLAPVQAYHSAQDMPPCDWLLVGAKTTG
NHELAPLIRAAAAPGAKVLLLQNGLGVEERLRPLLPESLHLLGGLCFICVHRGEPGVIEHQAYGGVNLGYHSGPADERRR
REIVEEGAALFRESGLESTAMPDLEQARWQKLVWNIPYNGLSVLLKSSTAPLMANADSRSLIEAIMEEVIGAAGACGFIL
PEGYADQLLAATERMPDYRPSMYHDFAHGRPLELAAIYAAPLARAAAAGYRMPRVEALHQALRFLEAQP

The query sequence (length=309) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ix9:C 314 309 1.0000 0.9841 1.0000 0.0 8ix9:B, 8ix9:A, 8ixh:A, 8ixh:B, 8ixh:C, 8ixm:A, 8ixm:B
2 3hwr:A 299 306 0.2718 0.2809 0.2745 2.42e-21 3hwr:B
3 5ayv:B 303 299 0.2654 0.2706 0.2742 6.35e-18 5ayv:A, 5hws:A, 5hws:B, 5hws:C, 5hws:D
4 4yca:B 286 238 0.1845 0.1993 0.2395 5.97e-10 4s3m:A, 4s3m:B, 4yca:A
5 5x20:A 312 310 0.2168 0.2147 0.2161 1.25e-09 3wfj:A, 3wfj:B, 3wfj:C, 3wfj:D, 3wfj:E, 3wfj:G, 5x20:B, 5x20:C, 5x20:D, 5x20:E
6 6k1r:A 305 300 0.2298 0.2328 0.2367 1.93e-07 6k1r:B, 6k1r:C, 5zix:A, 5zix:B
7 4ol9:A 297 279 0.2330 0.2424 0.2581 1.23e-04
8 2ofp:B 294 322 0.2427 0.2551 0.2329 5.52e-04 2ofp:A, 1yjq:A, 1yon:A
9 5x1y:B 454 170 0.1424 0.0969 0.2588 0.16 5x1y:A, 5x1y:C, 5x1y:D, 5x1y:E, 5x1y:F
10 7z67:A 393 108 0.0939 0.0738 0.2685 0.21
11 5t9f:B 253 120 0.1036 0.1265 0.2667 0.36 5t95:A, 5t95:B, 5t9e:A, 5t9e:B, 5t9f:A, 5whx:A, 5whx:B
12 1c0i:A 363 38 0.0518 0.0441 0.4211 0.61 1c0k:A, 1c0l:A, 1c0p:A
13 8x3v:B 209 55 0.0550 0.0813 0.3091 0.90 8x3v:A
14 6ruz:A 443 96 0.0841 0.0587 0.2708 1.1 6ruz:B, 6ruz:C, 6ruz:D, 6rvb:A, 6rvb:B, 6rvb:C, 6rvb:D, 6rvh:A, 6rvh:B, 6rvh:C, 6rvh:D
15 6v85:A 1901 68 0.0615 0.0100 0.2794 2.0 6v86:A
16 4gqu:A 191 24 0.0324 0.0524 0.4167 3.0 7ddv:A, 7dnq:A, 7fcy:A, 6khh:A, 4lom:A, 4lpf:A, 5xds:A, 6yjh:A, 5zqn:A
17 3wfj:F 263 305 0.2006 0.2357 0.2033 3.6 3wfj:H
18 2nvu:B 789 39 0.0485 0.0190 0.3846 4.9 3dbh:B, 3dbh:D, 3dbh:F, 3dbh:H, 3dbl:B, 3dbl:D, 3dbl:F, 3dbl:H, 3dbr:B, 3dbr:D, 3dbr:F, 3dbr:H, 3gzn:B, 3gzn:D, 1r4m:F, 1r4m:H, 1r4n:B, 1r4n:D, 1r4n:F, 1r4n:H, 1tt5:B, 1tt5:D, 1yov:B, 1yov:D
19 8t2g:A 333 65 0.0680 0.0631 0.3231 5.4 8t2g:B, 8uzd:A, 8uzd:B
20 3i3l:A 550 33 0.0453 0.0255 0.4242 5.9
21 5d00:A 361 28 0.0356 0.0305 0.3929 7.6 5d00:B, 5d01:A, 5d01:B
22 4kqx:B 335 48 0.0518 0.0478 0.3333 7.9 4kqw:A, 4kqw:B, 4kqx:A
23 2y0c:A 461 144 0.1133 0.0759 0.2431 8.1 2y0c:B, 2y0c:C, 2y0c:D, 2y0d:A, 2y0d:B, 2y0d:C, 2y0d:D, 2y0e:A, 2y0e:B, 2y0e:C, 2y0e:D
24 6vpb:B 324 31 0.0421 0.0401 0.4194 8.3
25 3din:A 816 65 0.0744 0.0282 0.3538 8.8 3din:B, 3jux:A, 4ys0:A
26 8po7:A 594 71 0.0615 0.0320 0.2676 9.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218