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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QRALVFSGQGAHRRGMATEYLRIPAVACLWERMKGSMEQKYGISLQDIITENPTRLYVYNDAYDVAAICERSCQDGGSVV
ESTPKQKLISHPQGVLSLTSLTQPCMLAAHMVSLEYLKETRGYSVESSEVIAGHSLGEFSALCALGVLSPEVAIDLVYRR
GALMEDAVKHSSQSNEGHLMFACNPQRAKLCVEDPDLAVDQLHIFVELIARNLSTTASFIEVVNYNISYEQYVVVGDPIA
LSALGKCLDPQFRATSCGSSATLDNIVRTAVSSVLQDKQEGITMNPNTGPAPDFVTSCARKYGIRSTFRRFLRGPDDGYT
PSLEELTHLTLQEDGRSGLKKKSWFIPLPLSIPFHSSMLRRAMDLFLPVVRDALPDEETMRSFFCIPVWLTNLTGTAFRP
FDVDFQRDALDAMQSMNVGEIRHNGRYHTNLVELAFKNGMDTSSVRDMCAAVLAAQLAHPVQWIDVMDSAVFQHGVREAH
EISPVRTVADMFKRTVFALDIVTRCLPSEERFL

The query sequence (length=513) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7pua:Fg 520 519 0.9981 0.9846 0.9865 0.0 7pub:Fg
2 7bc4:B 2054 264 0.1715 0.0428 0.3333 1.74e-28
3 4v58:G 2060 264 0.1618 0.0403 0.3144 1.28e-27 4v58:H, 4v58:I, 4v58:J, 4v58:K, 4v58:L, 4v59:G, 4v59:H, 4v59:I, 4v59:J, 4v59:K, 4v59:L
4 7tui:B 2033 264 0.1618 0.0408 0.3144 3.86e-26 6u5v:B, 6u5w:B
5 8ps2:G 2036 442 0.2047 0.0516 0.2376 2.78e-24 3hmj:G, 3hmj:H, 3hmj:I, 8prv:G, 8prw:G, 8prw:J, 8prw:I, 8prw:H, 8prw:K, 8prw:L, 8ps1:G, 8ps9:G, 8psa:G, 8psf:G, 8psg:G, 8psj:G, 8psk:G, 8psl:G, 8psm:G, 8psp:G, 6ql5:I, 6ql5:G, 6ql5:H, 6ql5:L, 6ql5:J, 6ql5:K, 6ql6:G, 6ql6:H, 6ql6:I, 6ql6:J, 6ql6:K, 6ql6:L, 6ql9:G, 6ql9:H, 6ql9:I, 6ql9:J, 6ql9:K, 6ql9:L, 6ta1:G, 6ta1:C, 6ta1:E, 6ta1:L, 6ta1:H, 6ta1:J, 6u5t:G, 6u5u:G, 2uv8:G, 2uv8:H, 2uv8:I, 2vkz:G, 2vkz:H, 2vkz:I
6 4v8l:D 2822 241 0.1287 0.0234 0.2739 2.47e-17 4ce4:o, 6hiv:US, 6hiv:UT, 6hiw:US, 6hiw:UT, 6hiy:US, 6hiy:UT, 4v8l:E, 4v8l:F, 4v8l:A, 4v8l:B, 4v8l:C, 4v8v:A, 4v8v:B, 4v8v:C, 4v8v:D, 4v8v:E, 4v8v:F, 4v8w:D, 4v8w:E, 4v8w:F, 4v8w:A, 4v8w:B, 4v8w:C
7 4v8l:D 2822 190 0.1033 0.0188 0.2789 0.002 4ce4:o, 6hiv:US, 6hiv:UT, 6hiw:US, 6hiw:UT, 6hiy:US, 6hiy:UT, 4v8l:E, 4v8l:F, 4v8l:A, 4v8l:B, 4v8l:C, 4v8v:A, 4v8v:B, 4v8v:C, 4v8v:D, 4v8v:E, 4v8v:F, 4v8w:D, 4v8w:E, 4v8w:F, 4v8w:A, 4v8w:B, 4v8w:C
8 6gjc:A 2770 241 0.1306 0.0242 0.2780 3.50e-17 6gjc:B, 6gjc:C, 6gjc:D, 6gjc:E, 6gjc:F
9 6gjc:A 2770 187 0.1014 0.0188 0.2781 0.001 6gjc:B, 6gjc:C, 6gjc:D, 6gjc:E, 6gjc:F
10 3tqe:A 316 82 0.0643 0.1044 0.4024 9.32e-08
11 5zk4:A 287 76 0.0663 0.1185 0.4474 1.81e-07 6apg:A, 6apg:B, 3sbm:A, 5zk4:B
12 3hjv:A 307 73 0.0643 0.1075 0.4521 2.32e-07
13 7vef:A 828 168 0.1014 0.0628 0.3095 5.67e-07 8in9:A
14 3im9:A 313 82 0.0585 0.0958 0.3659 1.12e-05
15 6u0j:A 309 81 0.0546 0.0906 0.3457 8.16e-05 2g2z:A
16 4mz0:A 896 73 0.0526 0.0301 0.3699 1.50e-04
17 8cg5:A 1282 62 0.0565 0.0226 0.4677 3.58e-04 6fij:B
18 8cg6:A 1208 62 0.0565 0.0240 0.4677 3.58e-04
19 6u5w:A 1435 51 0.0390 0.0139 0.3922 0.001
20 7cpx:A 2262 86 0.0507 0.0115 0.3023 0.027 7cpx:B, 7cpy:A, 7cpy:B
21 2qo3:B 873 84 0.0643 0.0378 0.3929 0.030 2qo3:A
22 8csp:8 326 76 0.0448 0.0706 0.3026 0.031 2c2n:A, 8csq:8, 8csr:8, 8css:8
23 7ags:A 427 93 0.0546 0.0656 0.3011 0.049 7agu:A
24 4mz0:B 823 63 0.0448 0.0279 0.3651 0.049
25 4amp:A 372 89 0.0507 0.0699 0.2921 0.073
26 7m7f:A 1390 60 0.0507 0.0187 0.4333 0.099 2fr0:A, 2fr1:A, 7m7i:A
27 6ql9:D 1765 49 0.0331 0.0096 0.3469 0.16 3hmj:A, 3hmj:B, 3hmj:C, 8prv:A, 8prv:B, 8prw:A, 8prw:B, 8prw:C, 8prw:D, 8prw:E, 8prw:F, 8ps1:A, 6ql6:F, 6ql6:E, 6ql6:D, 6ql6:C, 6ql6:B, 6ql6:A, 6ql9:F, 6ql9:A, 6ql9:E, 6ql9:B, 6ql9:C, 6ta1:A, 6ta1:B, 6ta1:D, 6ta1:K, 6ta1:F, 6ta1:I, 6u5u:A, 2vkz:A, 2vkz:B, 2vkz:C, 2wat:A, 2wat:B, 2wat:C, 2wat:D, 2wat:E, 2wat:F
28 4v59:D 1467 49 0.0312 0.0109 0.3265 0.21 4v59:A, 4v59:B, 4v59:C, 4v59:E, 4v59:F
29 5my0:A 852 140 0.0760 0.0458 0.2786 0.38 5my0:C, 5my0:D, 5my2:D, 6rop:A, 6rop:C, 6rop:D
30 6rop:B 831 101 0.0585 0.0361 0.2970 0.46
31 2jfk:D 410 37 0.0331 0.0415 0.4595 1.9
32 4d8f:B 334 140 0.0682 0.1048 0.2500 3.1 2ani:A, 4d8f:A, 4d8f:C, 4d8f:D, 4d8g:A, 4d8g:B, 4d8g:C, 4d8g:D, 4m1i:A, 4m1i:B, 4m1i:C, 4m1i:D, 1syy:A
33 5ydl:A 408 32 0.0253 0.0319 0.4062 3.2 5ydm:A
34 6ybh:D 219 59 0.0370 0.0868 0.3220 5.3 1j90:A, 1j90:B, 2jcs:A, 2jcs:B, 2jj8:A, 2jj8:B, 2jj8:C, 2jj8:D, 1oe0:A, 1oe0:B, 1oe0:C, 1oe0:D, 1ot3:A, 1ot3:B, 1ot3:C, 1ot3:D, 1ot3:E, 1ot3:F, 1ot3:G, 1ot3:H, 2vp0:A, 2vp0:B, 2vp2:A, 2vp2:B, 2vp4:A, 2vp4:B, 2vp4:C, 2vp4:D, 2vp5:A, 2vp5:B, 2vp6:A, 2vp6:B, 2vp6:C, 2vp6:D, 2vp6:E, 2vp6:F, 2vp6:G, 2vp6:H, 2vp9:A, 2vp9:B, 2vp9:C, 2vp9:D, 2vp9:E, 2vp9:F, 2vp9:G, 2vp9:H, 2vpp:A, 2vpp:B, 2vqs:A, 2vqs:B, 2vqs:C, 2vqs:D, 6ybh:A, 6ybh:B, 6ybh:C, 6ybh:E, 6ybh:F, 1zm7:A, 1zm7:B, 1zm7:C, 1zm7:D, 1zmx:A, 1zmx:B, 1zmx:C, 1zmx:D, 1zmx:E, 1zmx:F, 1zmx:G, 1zmx:H
35 7aih:M 259 28 0.0234 0.0463 0.4286 6.5 7am2:M, 7ane:M
36 6yxx:AW 278 27 0.0214 0.0396 0.4074 9.0 7aoi:AW, 6hiv:AW, 6hix:AW, 6yxy:AW
37 5ojg:A 260 60 0.0331 0.0654 0.2833 9.0 5ojg:B, 5oji:A, 5oji:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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