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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFST
VEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPV
LANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAIL
ELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSG
WSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLT
NDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDTVEVLAIDNTSVRNRQI
EKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESK
EITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGVSTLA
AGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQS

The query sequence (length=714) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xiq:A 714 714 1.0000 1.0000 1.0000 0.0 8dyj:B, 8dyl:B, 2xij:A, 2xiq:B
2 8gju:J 689 712 0.9650 1.0000 0.9677 0.0 8gju:K, 8gju:L, 8gju:H
3 6oxd:A 736 724 0.6148 0.5965 0.6064 0.0 6oxc:A
4 1e1c:A 727 711 0.5966 0.5860 0.5992 0.0 1e1c:C, 1req:A, 1req:C, 2req:A, 2req:C, 3req:A, 4req:A, 4req:C, 5req:A, 5req:C, 6req:A, 6req:C, 7req:A, 7req:C
5 4r3u:A 557 521 0.3053 0.3914 0.4184 3.89e-143 4r3u:B
6 8ssl:A 1072 531 0.2689 0.1791 0.3616 5.56e-80 5cjt:A, 5cjt:B, 5cju:A, 5cju:B, 5cjv:A, 5cjv:B, 5cjw:A, 5cjw:B, 8ssl:B, 8ssl:C, 4xc6:A, 4xc6:B, 4xc7:A, 4xc8:A, 4xc8:B
7 8ssl:A 1072 131 0.0490 0.0326 0.2672 0.18 5cjt:A, 5cjt:B, 5cju:A, 5cju:B, 5cjv:A, 5cjv:B, 5cjw:A, 5cjw:B, 8ssl:B, 8ssl:C, 4xc6:A, 4xc6:B, 4xc7:A, 4xc8:A, 4xc8:B
8 7req:D 623 477 0.2087 0.2392 0.3124 1.90e-43 1e1c:B, 1req:D, 5req:D, 6req:B
9 4r3u:C 131 107 0.0630 0.3435 0.4206 4.12e-20 4r3u:D
10 1cb7:A 137 122 0.0490 0.2555 0.2869 0.010 1cb7:C, 1ccw:A, 1ccw:C, 6h9e:A, 6h9e:C, 6h9f:A, 6h9f:C, 1i9c:A, 1i9c:C
11 8t0q:A 257 145 0.0560 0.1556 0.2759 0.26 8t0q:B, 8t0v:B
12 4dbe:A 213 56 0.0266 0.0892 0.3393 0.80 4dbe:B
13 1id8:A 137 121 0.0434 0.2263 0.2562 0.90
14 2c3c:A 522 82 0.0280 0.0383 0.2439 1.3 2c3c:B, 2c3d:A, 2c3d:B, 7mgn:A, 7mgn:B, 7mgo:B, 1mo9:A, 1mo9:B, 1mok:A, 1mok:B, 1mok:C, 1mok:D, 3q6j:A, 3q6j:B
15 8u7j:L 267 40 0.0210 0.0562 0.3750 1.4 8u7j:K, 8u7j:I, 8u9e:B
16 4n67:A 214 63 0.0280 0.0935 0.3175 1.5
17 7nup:D 884 57 0.0294 0.0238 0.3684 1.6 5ab0:C, 5ab2:B, 4e36:A, 4e36:B, 6ea4:A, 6ea4:B, 5j6s:B, 4jbs:A, 4jbs:B, 7nsk:B, 7nup:C, 7p7p:B, 7pfs:B, 3se6:A, 3se6:B
18 7pfs:A 916 57 0.0294 0.0229 0.3684 1.6 5ab0:A, 5ab2:A, 5j6s:A, 5k1v:A, 7nsk:A, 7nup:A, 7nup:B, 7p7p:A, 7sh0:A
19 3tc8:A 293 55 0.0280 0.0683 0.3636 1.7 3tc8:B
20 4z0c:A 709 105 0.0308 0.0310 0.2095 1.9 4z0c:D
21 2jk8:A 291 110 0.0378 0.0928 0.2455 2.5 5nh2:A
22 5upx:A 380 71 0.0322 0.0605 0.3239 2.8
23 5upy:A 350 71 0.0322 0.0657 0.3239 3.4
24 4wy0:B 260 40 0.0196 0.0538 0.3500 3.7 4wy0:D, 4wy0:E, 4wy0:G, 4wy0:I, 4wy0:J, 4wy0:K, 1znn:A, 1znn:B, 1znn:C, 1znn:D, 1znn:E, 1znn:F
25 4wgj:A 210 57 0.0252 0.0857 0.3158 4.1
26 2iss:B 285 40 0.0210 0.0526 0.3750 4.3 2iss:A, 2iss:C
27 3k6j:A 430 79 0.0294 0.0488 0.2658 5.5
28 4jgi:B 206 100 0.0434 0.1505 0.3100 6.1 4jgi:A
29 6mg0:B 1687 79 0.0294 0.0124 0.2658 6.3
30 6mfz:A 1789 79 0.0294 0.0117 0.2658 6.6 5es7:A, 5es8:A, 5es8:B, 5es9:A, 6mfw:A, 6mfx:A, 6mfy:A, 6mg0:A, 6ulz:A
31 1spg:B 147 76 0.0280 0.1361 0.2632 8.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218