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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNVSGPNYDKLKTELKNQEMATLFKDKNVDIYG
VEYYHLCYLCENAERSACIYGGVTNHEGNHLEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVRKYLTDNKQLY
TNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTTK

The query sequence (length=221) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1l0y:D 221 221 0.9955 0.9955 0.9955 1.25e-164 1ha5:A, 1ha5:B, 1ha5:C, 1ha5:D, 1l0y:B, 1uup:A, 1uup:B, 1uup:C, 1uup:D
2 1se3:A 239 236 0.5294 0.4895 0.4958 4.51e-70
3 1ck1:A 239 235 0.4977 0.4603 0.4681 1.34e-66 2aq2:B, 3bvg:A, 3bvm:A, 3bvz:A, 1cqv:A, 1i4p:A, 1i4q:A, 1i4r:A, 1i4x:A, 1ste:A, 1uns:A
4 5fka:C 221 221 0.3484 0.3484 0.3484 1.30e-27 4udu:C
5 2xn9:C 215 207 0.3620 0.3721 0.3865 5.43e-27 1ewc:A, 1hxy:D
6 1dyq:A 228 223 0.3258 0.3158 0.3229 4.54e-25 1i4g:A, 1i4h:A, 1i4h:B, 1sxt:A, 1sxt:B
7 2g9h:D 213 178 0.2489 0.2582 0.3090 4.68e-16
8 3ea6:A 215 224 0.3077 0.3163 0.3036 1.87e-15
9 2ici:A 227 223 0.3213 0.3128 0.3184 1.65e-14
10 1eu4:A 204 210 0.2986 0.3235 0.3143 1.96e-14
11 1hqr:D 205 165 0.2353 0.2537 0.3152 6.25e-14
12 1ty2:A 211 207 0.2851 0.2986 0.3043 1.17e-10 1ty2:B, 1ty2:C
13 1eu3:A 210 115 0.1900 0.2000 0.3652 9.38e-09 1eu3:B
14 2r61:A 195 105 0.1448 0.1641 0.3048 0.011 2z8l:A
15 2j4x:A 196 90 0.1357 0.1531 0.3333 0.020
16 2rdg:A 192 169 0.1900 0.2188 0.2485 0.050
17 2rgo:A 557 52 0.0860 0.0341 0.3654 0.15 2rgh:A
18 5j85:A 576 110 0.1222 0.0469 0.2455 0.76 9evv:A, 9evv:B, 9evv:C, 9evv:D, 5j84:A, 5j84:B, 5j84:C, 5j84:D, 5j84:E, 5j84:F, 5j84:G, 5j84:H
19 2iew:A 258 32 0.0588 0.0504 0.4062 1.1 2if8:A
20 4dxg:A 194 90 0.1176 0.1340 0.2889 1.4 4rco:A, 4rco:B
21 4kfz:B 148 109 0.1312 0.1959 0.2661 1.4 4kfz:A, 2xjy:A, 2xjz:A, 2xjz:B, 2xjz:C, 2xjz:D, 2xjz:E, 2ypa:C
22 6gsd:A 364 75 0.0905 0.0549 0.2667 2.2 5mlh:A, 5mlm:A, 5mlr:A
23 5gug:A 1721 81 0.1041 0.0134 0.2840 3.8 5gug:B, 1n4k:A, 3t8s:B, 3uj0:A, 3uj0:B, 5xa1:A, 5xa1:B
24 1g87:B 613 60 0.0724 0.0261 0.2667 3.8 1g87:A, 1ga2:A, 1ga2:B, 1k72:A, 1k72:B, 1kfg:A, 1kfg:B
25 4rfb:A 194 64 0.0995 0.1134 0.3438 4.3 4rfb:D, 4rfb:B, 4rfb:C, 4rgt:A, 4rgt:B
26 6el3:A 364 59 0.0814 0.0495 0.3051 5.5 6el3:B, 6el3:C, 6el3:D, 6el3:E, 6el3:F
27 7s0m:B 305 94 0.0950 0.0689 0.2234 7.2 7s0m:A
28 1pgu:B 608 60 0.0814 0.0296 0.3000 9.6 1pgu:A, 1pi6:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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