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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTT
EGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQ
KFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHE
EGHMLNCTCWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQT

The query sequence (length=301) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3m7p:A 301 301 1.0000 1.0000 1.0000 0.0
2 3ejh:A 91 89 0.2658 0.8791 0.8989 7.01e-52 3ejh:B, 3gxe:B, 3gxe:A
3 1gxd:A 624 133 0.2093 0.1010 0.4737 1.56e-35 1ck7:A, 1eak:A, 1eak:B, 1eak:D, 1eak:C, 1gen:A, 1gxd:B, 1rtg:A
4 1gxd:A 624 145 0.2126 0.1026 0.4414 3.44e-34 1ck7:A, 1eak:A, 1eak:B, 1eak:D, 1eak:C, 1gen:A, 1gxd:B, 1rtg:A
5 1gxd:A 624 63 0.1163 0.0561 0.5556 1.44e-16 1ck7:A, 1eak:A, 1eak:B, 1eak:D, 1eak:C, 1gen:A, 1gxd:B, 1rtg:A
6 1l6j:A 405 140 0.2027 0.1506 0.4357 7.71e-35
7 1l6j:A 405 194 0.2558 0.1901 0.3969 3.61e-34
8 1l6j:A 405 73 0.1130 0.0840 0.4658 1.88e-17
9 5xts:A 460 101 0.1229 0.0804 0.3663 1.52e-14 5xtw:A, 5xtw:C, 5xtw:D, 5xtw:E, 5xtw:F, 5xtw:H
10 5xts:A 460 52 0.0731 0.0478 0.4231 5.48e-09 5xtw:A, 5xtw:C, 5xtw:D, 5xtw:E, 5xtw:F, 5xtw:H
11 5e4k:A 424 95 0.1262 0.0896 0.4000 7.58e-14
12 5e4k:A 424 60 0.0930 0.0660 0.4667 4.97e-11
13 5e4l:A 428 52 0.0897 0.0631 0.5192 3.02e-13
14 5e4l:A 428 60 0.0930 0.0654 0.4667 5.35e-11
15 5e4l:B 386 52 0.0897 0.0699 0.5192 3.77e-13
16 5e4l:B 386 60 0.0930 0.0725 0.4667 5.95e-11
17 1h8p:A 88 104 0.1130 0.3864 0.3269 2.52e-10 1h8p:B
18 7prj:A 55 58 0.0831 0.4545 0.4310 6.06e-10
19 7prj:A 55 48 0.0664 0.3636 0.4167 2.20e-09
20 2rky:C 92 82 0.0897 0.2935 0.3293 2.44e-08 2rky:A, 2rl0:A, 2rl0:B, 2rl0:D, 2rl0:F, 2rl0:K
21 2rky:C 92 78 0.0963 0.3152 0.3718 3.38e-08 2rky:A, 2rl0:A, 2rl0:B, 2rl0:D, 2rl0:F, 2rl0:K
22 2rky:C 92 43 0.0532 0.1739 0.3721 0.18 2rky:A, 2rl0:A, 2rl0:B, 2rl0:D, 2rl0:F, 2rl0:K
23 2rkz:C 90 85 0.0930 0.3111 0.3294 2.83e-07 3cal:A, 3cal:C, 4pz5:A, 2rkz:A, 2rkz:B, 2rkz:D, 2rkz:E, 2rkz:F, 3zrz:A, 3zrz:B
24 2rkz:C 90 81 0.0930 0.3111 0.3457 2.54e-06 3cal:A, 3cal:C, 4pz5:A, 2rkz:A, 2rkz:B, 2rkz:D, 2rkz:E, 2rkz:F, 3zrz:A, 3zrz:B
25 2rkz:C 90 41 0.0465 0.1556 0.3415 0.38 3cal:A, 3cal:C, 4pz5:A, 2rkz:A, 2rkz:B, 2rkz:D, 2rkz:E, 2rkz:F, 3zrz:A, 3zrz:B
26 2rl0:I 79 77 0.0897 0.3418 0.3506 6.37e-07
27 2rl0:I 79 42 0.0532 0.2025 0.3810 0.27
28 1o9a:A 93 120 0.0963 0.3118 0.2417 0.005
29 1o9a:A 93 58 0.0631 0.2043 0.3276 0.14
30 2xfg:A 446 44 0.0465 0.0314 0.3182 0.14
31 4dod:A 454 44 0.0498 0.0330 0.3409 0.87 4doe:A
32 2dpt:A 232 45 0.0465 0.0603 0.3111 5.3 2dpt:B, 2z3k:A, 2z3k:B, 2z3l:B, 2z3l:A, 2z3m:A, 2z3m:B, 2z3n:A, 2z3n:B, 2z3o:A, 2z3o:B, 2z3p:A, 2z3p:B
33 8bxk:A 265 41 0.0332 0.0377 0.2439 7.6 8bxk:B, 8cqh:A, 8qdj:A
34 5k1b:A 264 100 0.0764 0.0871 0.2300 7.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218