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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QPAHLCFRSFVEALKVDNDLVEINTPIDPNLEAAAITRRVCETNDKAPLFNNLIGMKNGLFRILGAPGSLRKSSADRYGR
LARHLALPPTASMREILDKMLSASDMPPIPPTIVPTGPCKENSLDDSEFDLTELPVPLIHKSDGGKYIQTYGMHIVQSPD
GTWTNWSIARAMVHDKNHLTGLVIPPQHIWQIHQMWKKEGRSDVPWALAFGVPPAAIMASSMPIPDGVTEAGYVGAMTGS
SLELVKCDTNDLYVPATSEIVLEGTLSISETGPEGPFGEMHGYIFPGDTHLGAKYKVNRITYRNNAIMPMSSCGRLTDET
HTMSGSLAAAEIRKLCQQNDLPITDAFAPFESQVTWVALRVDTEKLRAMKTTSEGFRKRVGDVVFNHKAGYTIHRLVLVG
DDIDVYEGKDVLWAFSTRCRPGMDETLFEDVRGFPLIPYMGHGNGPAHRGGKVVSDALMPTEYTTGRNWEAADFNQSYPE
DLKQKVLDNWTKMGFSHHHH

The query sequence (length=500) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7nf4:A 504 503 0.9920 0.9841 0.9861 0.0 8crd:A, 6ev3:A, 6ev4:A, 6ev5:A, 6ev6:A, 6ev7:A, 6ev8:A, 6ev9:A, 6eva:A, 6evb:A, 6evc:A, 6evd:A, 7nf3:A, 7nf4:B, 8oed:A, 8oeh:A, 8oeo:A, 6r2p:A, 6r2r:A, 6r2t:A, 6r2z:A, 6r30:A, 6r32:A, 6r33:A, 6r34:A, 6r3f:A, 6r3g:A, 6r3i:A, 6r3j:A, 6r3l:A, 6r3n:A, 6r3o:A, 6tib:AAA, 6tic:AAA, 6tie:AAA, 6tih:AAA, 6tij:AAA, 6til:AAA, 6tin:AAA, 6tio:AAA, 4za4:A, 4za5:A, 4za7:A, 4za8:A, 4za9:A, 4zaa:A, 4zab:A
2 7ney:A 497 495 0.7000 0.7042 0.7071 0.0 7ney:B, 7nf0:A, 7nf0:B, 7nf1:A, 7nf1:B, 7nf2:A, 7nf2:B
3 6evf:A 503 495 0.4840 0.4811 0.4889 3.43e-178 6eve:A, 6eve:B, 6eve:C, 6eve:D, 6evf:B, 6evf:C, 6evf:D, 4s13:C, 4s13:F, 4zac:A, 4zac:B, 4zac:C, 4zac:D
4 4s13:A 472 494 0.4560 0.4831 0.4615 5.57e-159 4s13:G
5 4zad:A 511 508 0.4820 0.4716 0.4744 1.44e-157 4zad:B
6 4ip2:C 502 494 0.4060 0.4044 0.4109 3.34e-128 7abn:D, 7abn:A, 7abn:H, 7abn:M, 7abo:C, 7abo:B, 7abo:D, 7abo:A, 4ip2:A, 4ip2:B
7 6da9:A 463 487 0.3280 0.3542 0.3368 1.28e-81
8 5m1d:A 469 469 0.2620 0.2793 0.2793 2.80e-41 5m1d:B, 5m1d:C, 5m1e:A, 5m1e:B, 5m1e:C
9 7pda:A 477 428 0.2480 0.2600 0.2897 8.44e-31
10 6h6v:F 446 348 0.2060 0.2309 0.2960 5.62e-29 6h6v:A, 6h6v:B, 6h6v:C, 6h6v:D, 6h6v:E, 6h6x:B, 6h6x:A
11 7ae4:A 476 471 0.2540 0.2668 0.2696 5.10e-28 7ae4:B, 7ae4:C, 7ae4:D, 7ae4:E, 7ae4:F
12 5o3n:A 488 492 0.2380 0.2439 0.2419 4.11e-21 5o3n:B
13 5o3m:A 493 492 0.2440 0.2475 0.2480 1.33e-19 5o3m:B, 5o3m:C, 5o3m:D, 5o3m:E, 5o3m:F
14 8oz5:A 514 448 0.2080 0.2023 0.2321 7.36e-18 8oz5:B, 8oz5:C, 8oz5:D, 8oz5:E, 8oz5:F, 8p02:A, 8p02:B, 8p02:C, 8p02:D, 8p02:E, 8p02:F, 8pmk:A, 8pmk:B, 8pmk:C, 8pmk:D, 8pmk:E, 8pmk:F
15 7p9q:A 454 470 0.2260 0.2489 0.2404 4.38e-15 7p9q:B, 7p9q:C, 7p9q:D, 7p9q:E, 7p9q:F
16 6akv:A 151 91 0.0520 0.1722 0.2857 2.2
17 1lf9:A 674 85 0.0480 0.0356 0.2824 2.6 1lf9:B
18 2p20:A 641 67 0.0460 0.0359 0.3433 3.3 5jrh:A, 5jrh:B, 2p20:B, 2p2b:A, 2p2b:B, 2p2f:A, 2p2f:B, 2p2j:A, 2p2j:B, 2p2m:A, 2p2m:B, 2p2q:A, 2p2q:B, 1pg3:A, 1pg3:B, 1pg4:A, 1pg4:B
19 1itw:A 740 66 0.0420 0.0284 0.3182 3.8 1itw:B, 1itw:C, 1itw:D, 1j1w:A, 1j1w:B, 1j1w:C, 1j1w:D
20 7uk7:A 389 66 0.0380 0.0488 0.2879 5.3
21 2nvu:B 789 76 0.0340 0.0215 0.2237 6.9 3dbh:B, 3dbh:D, 3dbh:F, 3dbh:H, 3dbl:B, 3dbl:D, 3dbl:F, 3dbl:H, 3dbr:B, 3dbr:D, 3dbr:F, 3dbr:H, 3gzn:B, 3gzn:D, 1r4m:F, 1r4m:H, 1r4n:B, 1r4n:D, 1r4n:F, 1r4n:H, 1tt5:B, 1tt5:D, 1yov:B, 1yov:D
22 2dq0:A 447 57 0.0360 0.0403 0.3158 7.6 2dq0:B, 2zr2:A, 2zr2:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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