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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QMLTRKEDLLTVLKQISALKYVSNLYEFLLATEKIVQTSELDTQFQEFLTTTIIASEQNLVENYKQKYNQPNFSQLTIKQ
VIDDSIILLGNKQNYVQQIGTTTIGFYVEYENINLSRQTLYSSNFRNLLNIFGEEDFKYFLIDFLVFTKVEQNGYLQVAG
VCLNQYFSVQKQENQYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYQSKNFSCQEERDLFLEFTEKIVQNFHNINFNYLL
KKFCKLPENYQSLKSQVKQIVQSENKANQQSCENLFNSLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYE
FVQMKRFENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFIINKIVIPVLRYNFYITEKHKEGSQ
IFYYRKPIWKLVSKLTIVKLEEFQKYPQGKLRIIPKKGSFRPIMTFLRKDKQKNIKLNLNQILMDSQLVFRNLKDMLGQK
IGYSVFDNKQISEKFAQFIEKWKNKGRPQLYYVTLDIKKCYDSIDQMKLLNFFNQSDLIQDTYFINKYLLFQRNKRPLLQ
IQNFPYYFNLKERQIAYSLYDDDDQILQKGFKEIQSDDRPFIVINQDKPRCITKDIIHNHLKHISQYNVISFNKVKFRQK
RGIPQGLNISGVLCSFYFGKLEEEYTQFLKNAEQVNGSINLLMRLTDDYLFISDSQQNALNLIVQLQNCANNNGFMFNDQ
KITTNFQFPQEDYNLEHFKISVQNECQWIGKSIDMNTLEIKSIQKQTQQEINQTINVAISIKNLKSQLKNKLRSLFLNQL
IDYFNPNINSFEGLCRQLYHHSKATVMKFYPFMTKLFQIDLKKSKQYSVQYGKENTNENFLKDILYYTVEDVCKILCYLQ
FEDEINSNIKEIFKNLYSWIMWDIIVSYLKKKKQFKGYLNKLLQKIRKSRFFYLKEGCKSLQLILSQQKYQLNKKELEAI
EFIDLNNLIQDIKTLIPKIS

The query sequence (length=980) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6d6v:A 980 980 1.0000 1.0000 1.0000 0.0 5c9h:B
2 8gap:A 1012 1013 0.9949 0.9634 0.9625 0.0 5c9h:A, 7lma:A, 7lmb:A, 7uy5:A, 7uy6:A
3 7qxa:A 954 665 0.1500 0.1541 0.2211 1.11e-27 7bg9:A, 7qxb:A, 7qxs:A, 7trd:A, 7tre:A, 7trf:A
4 7v99:A 991 670 0.1500 0.1483 0.2194 3.20e-27 5ugw:A
5 6zdp:A 683 493 0.1092 0.1567 0.2170 2.38e-15
6 6zdu:A 693 452 0.0990 0.1400 0.2146 7.88e-07 6zdq:A, 6zdu:B
7 5cqg:A 596 182 0.0408 0.0671 0.2198 0.009 5cqg:B, 6e53:A, 7kqm:A, 7kqn:A, 7kqn:D, 3kyl:A, 6uso:A, 6usp:A, 6usq:A, 6usr:A
8 5gky:A 3660 160 0.0367 0.0098 0.2250 0.32 5gky:C, 5gky:E, 5gky:G, 5gkz:A, 5gkz:C, 5gkz:E, 5gkz:G, 5gl0:A, 5gl0:C, 5gl0:E, 5gl0:G, 5gl1:A, 5gl1:C, 5gl1:E, 5gl1:G
9 3j8h:A 3660 160 0.0367 0.0098 0.2250 0.37 3j8h:C, 3j8h:E, 3j8h:G
10 5tth:A 671 51 0.0173 0.0253 0.3333 3.0 6d14:A, 7exp:A, 4ipe:A, 4ivg:A, 4iyn:A, 4j0b:A, 4mli:A, 4mli:C, 4mls:A, 5tvu:A, 5tvw:A, 5tvx:A
11 7kcl:B 614 51 0.0173 0.0277 0.3333 3.3 7c04:A, 7c7b:A, 5f5r:A, 5f5r:B, 5hph:A, 5hph:B, 7kck:A, 7kck:B, 7kcl:A, 7kcm:A, 7kcm:B, 7klu:A, 7klu:B, 7klu:D, 7klu:C, 7klv:A, 7klv:B, 6xg6:A, 6xg6:B, 4z1i:A, 4z1i:B, 4z1i:C, 4z1i:D
12 5tth:B 621 51 0.0173 0.0274 0.3333 3.6 6d14:B, 7exp:B, 4ipe:B, 4iyn:B, 4j0b:B, 5tvu:B, 5tvw:B, 5tvx:B
13 7zol:B 1702 60 0.0173 0.0100 0.2833 4.4 7zoq:B
14 6ly5:G 214 44 0.0153 0.0701 0.3409 5.2 6l4t:8, 6l4u:8
15 4jb0:A 367 49 0.0184 0.0490 0.3673 5.6 4eyq:A, 4fb4:A, 3tx6:A, 3uk0:A, 3ukj:A
16 4q4a:A 572 45 0.0163 0.0280 0.3556 9.4 3qf4:A, 6quz:A, 6quz:C, 6qv0:A, 6qv0:C, 6qv1:A, 6qv1:C, 6qv2:A, 6qv2:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218