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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIAEAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAK
DQEDRQEPQKNKKLHLIPLFTSMAVAAARIGKEEVSVPFSGGMPGEEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTM
NVEGVSSVLAILFDIVNGEIVEAEIGESYAINDLGAGTSDNAFFEDGELNKKLSTNTDLGTNKYIDEILKNIKERFMPFK
TREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGDVKENVTDIVMDGMLKYAEDQKASLMKFWFKTNADKNIVVGGGVLFGY
AGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLEQLNEQMLSKNMLLGGFDTGNIKAKISFLNEKGNIESFAIPTVIA
EAPPAKIKDEDIELLHVRIISNSLDGDARSRAWYVGAYAKDQEDRQEPTVQKNKKLHLIPLFTSMAVAAARIGKEEVSVP
FSGGMEQILEMLYGEHTVEFLDGTYEGKKIKITINDGTMNVEGVSSVLAILFDIVNGEIVEVEGGESYAINDLGAGTSDN
AFFEDGELNLSTNTDLGTNKYIDEILKNIKERFMENEIIESPFKTREDFIQRLVMPEVEKMIEDDTYKPTFSVKWGPVKE
NVTDIVMDGMLKYAEDQKASLDKFWDKTNADKNIVVGGGVLFGYAGLRDLKEQDGFILPKNIQESAYFTSRSYLIANLLE
QLN

The query sequence (length=723) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4xhp:A 723 723 1.0000 1.0000 1.0000 0.0
2 4xho:A 369 373 0.4910 0.9621 0.9517 0.0 4xe8:A, 4xhn:A
3 4xho:A 369 369 0.4841 0.9485 0.9485 0.0 4xe8:A, 4xhn:A
4 7kzv:V 1155 168 0.0664 0.0416 0.2857 0.003 8a9k:B
5 7kzv:V 1155 173 0.0609 0.0381 0.2543 0.16 8a9k:B
6 6vaa:B 1153 168 0.0664 0.0416 0.2857 0.003
7 6vaa:B 1153 173 0.0609 0.0382 0.2543 0.16
8 6bqw:A 275 234 0.0761 0.2000 0.2350 0.007 6bqw:B, 6bqw:C, 6bqw:D, 6bqw:E, 6bqw:F, 6bqw:G, 6bqw:H, 6bqw:I, 6f95:A, 6f95:B, 6f95:C, 6f95:D, 6f95:E
9 6bqw:A 275 215 0.0733 0.1927 0.2465 1.8 6bqw:B, 6bqw:C, 6bqw:D, 6bqw:E, 6bqw:F, 6bqw:G, 6bqw:H, 6bqw:I, 6f95:A, 6f95:B, 6f95:C, 6f95:D, 6f95:E
10 3h1q:B 272 72 0.0304 0.0809 0.3056 0.46 3h1q:A
11 7bvy:A 333 57 0.0221 0.0480 0.2807 0.67 7bvz:A
12 7bvy:A 333 79 0.0332 0.0721 0.3038 4.6 7bvz:A
13 6pc1:B 483 126 0.0415 0.0621 0.2381 1.7 6pc1:A, 6pc1:C, 6pc1:D, 6pc2:A, 6pc2:B, 6pc3:A, 6pc3:B
14 8a0p:A 216 106 0.0373 0.1250 0.2547 6.1 8a08:A, 8a0i:A, 8a0o:A, 8a0q:A, 8a0r:A, 7zvp:A, 7zzn:A
15 8e3s:A 503 125 0.0456 0.0656 0.2640 8.5 8fzr:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218