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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFIKL

The query sequence (length=51) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5a2q:d 55 51 1.0000 0.9273 1.0000 2.07e-33 7a01:H3, 7a09:l, 5aj0:Bd, 9bdl:AS29, 9bdn:AS29, 9bdp:AS29, 8bhf:e3, 9bkd:i, 9bln:i, 8btk:AG, 7cpu:Sd, 7cpv:Sd, 4d5l:d, 4d61:d, 6d90:ee, 6d9j:ee, 9f1b:AG, 9f1c:AG, 9f1d:AG, 6fec:J, 5flx:d, 6g51:d, 6g53:d, 6g5h:d, 6g5i:d, 8g5y:Sd, 8g5z:Sd, 8g60:Sd, 8g61:Sd, 8g6j:Sd, 8glp:Sd, 6gz3:Bd, 6gz4:Bd, 6gz5:Bd, 6hcf:e1, 6hcj:e2, 6hcm:e1, 6hcq:e2, 8ifd:3E, 8ife:3E, 6ip5:3E, 6ip6:3E, 6ip8:3E, 3j7p:Sd, 3j7r:Sd, 3jag:dd, 3jah:dd, 3jai:dd, 3jaj:Sd, 3jan:Sd, 8jdj:AP, 8jdk:AP, 8jdl:AP, 8jdm:AP, 5k0y:J, 8k2c:Sd, 7k5i:d, 4kzx:d, 4kzy:d, 4kzz:d, 5lks:Sd, 7ls1:H3, 7ls2:H3, 5lzs:dd, 5lzt:dd, 5lzu:dd, 5lzv:dd, 5lzw:dd, 5lzx:dd, 5lzy:dd, 5lzz:dd, 7mdz:dd, 6mtb:dd, 6mtc:dd, 6mtd:dd, 6mte:dd, 7nwg:e2, 7nwh:dd, 7nwi:dd, 7o7y:AG, 7o7z:AG, 7o80:AG, 7o81:AG, 5oa3:d, 6ole:Sd, 6olf:Sd, 6olg:Bd, 6oli:Sd, 6olz:Bd, 6om0:Sd, 6om7:Sd, 7oya:d2, 7oyb:d2, 7oyc:d2, 7oyd:Dd, 8oz0:o, 8p03:e, 8p09:e, 8p2k:AG, 6p4g:e, 6p4h:e, 6p5i:e, 6p5j:e, 6p5k:e, 6p5n:e, 8pj1:i, 8pj2:i, 8pj3:i, 8pj4:i, 8pj5:i, 8pj6:i, 8ppk:d, 8ppl:Ad, 8q7z:AG, 8q87:AG, 7qgg:Sd, 8qoi:Sd, 7qp6:i, 7qp7:i, 7qvp:Sd, 7qvp:Rd, 6qzp:Sd, 7r4x:d, 6r5q:9, 6r6g:9, 6r6p:w, 6r7q:9, 8scb:dd, 6sgc:e1, 7syg:e, 7syh:e, 7syi:e, 7syj:e, 7syk:e, 7syl:e, 7sym:e, 7syn:e, 7syo:e, 7syp:e, 7syq:e, 7syr:e, 7sys:e, 7syt:e, 7syu:e, 7syv:e, 7syw:e, 7syx:e, 5t2c:AG, 8t4s:d, 7toq:AS29, 7tor:AS29, 7tql:f, 7ucj:Dd, 7uck:Dd, 4ug0:Sd, 4ujc:Cd, 4ujd:Cd, 4uje:Bd, 4v5z:An, 4v6x:Ad, 5vyc:d1, 5vyc:d2, 5vyc:d3, 5vyc:d4, 5vyc:d5, 5vyc:d6, 6w2s:e, 6w2t:e, 6xa1:Sd, 7xnx:Sd, 7xny:Sd, 8xsx:Sd, 8xsy:Sd, 8xsz:Sd, 8xxl:Sd, 8xxm:Sd, 8xxn:Sd, 6y0g:Sd, 8y0w:Sd, 8y0x:Sd, 6y2l:Sd, 6y57:Sd, 6yal:e, 6yam:e, 6yan:e, 6ybs:i, 8yoo:Sd, 8yop:Sd, 6z6l:Sd, 6z6m:Sd, 6z6n:Sd, 7zjw:SH, 7zjx:SH, 6zlw:f, 6zm7:Sd, 6zme:Sd, 6zmi:Sd, 6zmo:Sd, 6zmt:f, 6zmw:i, 6zn5:f, 6zoj:d, 6zol:d, 6zon:l, 6zp4:l, 6zuo:d, 6zv6:d, 6zvh:d, 6zvj:l, 6zvk:H3, 6zxd:d, 6zxe:d, 6zxf:d, 6zxg:d, 6zxh:d
2 4v6w:Ad 52 50 0.8039 0.7885 0.8200 2.59e-26 6xu6:Ad, 6xu7:Ad, 6xu8:Ad
3 9bh5:Ad 55 51 0.7255 0.6727 0.7255 4.52e-23 9cai:Ad
4 7a1g:M 53 51 0.6667 0.6415 0.6667 4.35e-21 7b7d:M, 8bn3:D9, 8bqd:M, 8bqx:M, 8cah:M, 8cas:N, 8cbj:d, 8ccs:5, 8cdl:5, 8cdr:5, 8ceh:5, 8cf5:5, 8cg8:5, 8cgn:5, 8civ:5, 8cku:5, 8cmj:5, 5dat:D9, 5dat:d9, 5dc3:D9, 5dc3:d9, 5dge:D9, 5dge:d9, 5dgf:D9, 5dgf:d9, 5dgv:D9, 5dgv:d9, 8eub:Bd, 8evp:Bd, 8evq:Bd, 8evr:Bd, 8evs:Bd, 8evt:Bd, 8ewb:Bd, 8ewc:Bd, 6fai:d, 5fci:D9, 5fci:d9, 5fcj:D9, 5fcj:d9, 6gq1:AT, 6gqb:AT, 6gqv:AT, 6hhq:e, 6hhq:d9, 5i4l:D9, 5i4l:d9, 6i7o:M, 6i7o:Mb, 3j6x:29, 3j6y:29, 3j77:29, 3j78:29, 5juo:AC, 5jup:AC, 5jus:AC, 5jut:AC, 5juu:AC, 8k2d:Sd, 8k82:Sd, 5lyb:D9, 5lyb:d9, 5m1j:d2, 5mc6:M, 5mei:d9, 5mei:e, 7mpi:Bd, 7mpj:Bd, 7n8b:Bd, 5ndg:D9, 5ndg:d9, 5ndv:D9, 5ndv:d9, 5ndw:D9, 5ndw:d9, 7nrc:SM, 7nrd:SM, 5obm:D9, 5obm:d9, 5on6:d9, 5on6:e, 7osa:uS14, 7osm:uS14, 6q8y:M, 6rbd:d, 6rbe:d, 7rr5:Sd, 6s47:Be, 6snt:d, 6sv4:M, 6sv4:Mb, 6sv4:Mc, 6t4q:Sd, 6t7i:Sd, 6t7t:Sd, 6t83:db, 6t83:4, 5tbw:e, 5tbw:d9, 6tb3:M, 5tga:D9, 5tga:d9, 5tgm:D9, 5tgm:d9, 6tnu:M, 4u3m:D9, 4u3m:d9, 4u3n:D9, 4u3n:d9, 4u3u:D9, 4u3u:d9, 4u4n:D9, 4u4n:d9, 4u4o:D9, 4u4o:d9, 4u4q:D9, 4u4q:d9, 4u4r:D9, 4u4r:d9, 4u4u:D9, 4u4u:d9, 4u4y:D9, 4u4y:d9, 4u4z:D9, 4u4z:d9, 4u50:D9, 4u50:d9, 4u51:D9, 4u51:d9, 4u52:D9, 4u52:d9, 4u53:D9, 4u53:d9, 4u55:D9, 4u55:d9, 4u56:D9, 4u56:d9, 4u6f:D9, 4u6f:d9, 4uer:N, 4v6i:AN, 4v7h:AN, 4v7r:AS, 4v7r:CS, 4v88:Ad, 4v88:Cd, 4v8y:A3, 4v8z:A3, 4v92:Bd, 6wdr:d, 6woo:dd, 6xiq:AT, 6xir:AT, 8y0u:Sd, 6z6j:Sd, 6z6k:Sd, 6zce:e, 7zpq:Ad, 7zrs:Ad, 6zu9:N, 7zuw:Ad, 7zux:Dd, 6zvi:O, 7zw0:sM
5 5xxu:d 51 49 0.6471 0.6471 0.6735 1.75e-20
6 8r57:d 55 50 0.6863 0.6364 0.7000 2.47e-20 8ip8:wa, 8ip9:wa, 8ipa:wa, 8ipb:wa, 8jiw:Bd, 4v3p:SN, 4v7e:Bd
7 7r81:e2 55 50 0.6471 0.6000 0.6600 6.65e-20 7olc:Sd, 7old:Sd, 8oo0:Sd, 7z3n:Sd, 7z3o:Sd
8 8c3a:f 55 50 0.6471 0.6000 0.6600 9.87e-20 8c3a:DQ, 8cq7:f, 8cq7:DQ, 8cqw:f, 8cqw:DQ, 8cre:f, 8cre:DQ, 8oeq:f, 8oeq:DQ, 7pzy:e, 7q08:e, 7q0f:e, 7q0p:e, 7q0r:e, 8q5i:e
9 3j7a:T 48 45 0.6078 0.6458 0.6889 3.21e-19 3jbn:T, 3jbo:T, 3jbp:T, 6okk:T, 8tpu:ST
10 8auv:V 55 50 0.6078 0.5636 0.6200 8.31e-19 8b2l:V1, 7qiy:N, 7qiz:XA
11 6fyx:d 55 50 0.6078 0.5636 0.6200 2.97e-18 6fyy:d, 6gsm:d, 6gsn:d, 8i7j:d, 5it7:d, 5it9:d, 3j80:d, 3j81:d, 3jam:d, 3jap:d, 8rw1:d, 8s8d:d, 8s8e:d, 8s8f:d, 8s8g:d, 8s8h:d, 8s8i:d, 8s8j:d, 6uz7:d
12 4bts:AN 54 50 0.5098 0.4815 0.5200 6.05e-15 4bts:BN, 4bts:CN, 4bts:DN, 4v5o:AN, 4v5o:BN
13 6zu5:SDD 59 45 0.5294 0.4576 0.6000 2.90e-14
14 8rxh:SS 56 42 0.5098 0.4643 0.6190 9.03e-14 8a3w:SS, 8a98:SS, 6az1:S, 8ove:A8, 8ovj:SS, 8rxx:SS, 5t2a:8
15 7ase:Q 57 42 0.5098 0.4561 0.6190 9.04e-14 5opt:q, 8ova:A8, 4v8m:A8
16 5xyi:d 52 47 0.5098 0.5000 0.5532 4.95e-12
17 6rm3:SDD 67 45 0.4314 0.3284 0.4889 1.12e-11
18 8p5d:SDD 65 46 0.4510 0.3538 0.5000 1.13e-11 8p60:SDD, 8p60:RDD, 7qca:SDD
19 7qep:D9 65 44 0.5294 0.4154 0.6136 1.25e-11
20 8hkx:S14P 52 43 0.4314 0.4231 0.5116 2.84e-10 8hky:S14P, 8hkz:S14P, 8hl1:S14P, 8hl2:S14P, 8hl3:S14P, 8hl4:S14P, 8hl5:S14P, 8wkp:S14P, 8wq2:S14P, 8wq4:S14P
21 6zj3:SS 52 32 0.3922 0.3846 0.6250 1.39e-09
22 6tmf:Q 56 44 0.4314 0.3929 0.5000 1.61e-09
23 8fvy:d 85 37 0.3922 0.2353 0.5405 3.01e-09 8br8:Sh, 8brm:Sh, 8bsi:Sh, 8bsj:Sh, 8btd:Sh, 8btr:Sh, 8g4s:d, 7pwf:d, 7pwo:d1
24 5jb3:P 56 44 0.4314 0.3929 0.5000 7.79e-09 5jbh:P, 6skf:Ar, 6skg:Ar, 6sw9:P, 6swc:P, 6swe:P, 6th6:Ar, 4v4n:BP, 4v6u:AP, 7zag:P, 7zah:P, 7zai:P, 7zhg:P
25 8fmw:N 60 29 0.2353 0.2000 0.4138 0.37
26 6yef:n 60 30 0.2157 0.1833 0.3667 1.4
27 3ubx:L 214 15 0.1569 0.0374 0.5333 3.7 3ubx:I
28 8u4j:B 600 33 0.2157 0.0183 0.3333 7.1
29 5ait:A 129 49 0.2745 0.1085 0.2857 8.0 5aiu:A, 4ap4:A, 3ng2:A, 3ng2:B, 4ppe:A, 4ppe:B, 2xeu:A
30 5ow5:A 170 23 0.1765 0.0529 0.3913 8.8 5ow5:C
31 6x67:C 478 28 0.1569 0.0167 0.2857 8.9 5lme:A, 6x67:D, 6x68:C, 6x68:D
32 3x3m:A 397 33 0.2549 0.0327 0.3939 8.9 5ebc:A, 3x3n:A
33 4ydv:L 206 13 0.1569 0.0388 0.6154 9.6 4ydv:A
34 2bjj:X 692 39 0.2549 0.0188 0.3333 9.6 1b0l:A, 1bka:A, 1cb6:A, 1dsn:A, 1eh3:A, 1fck:A, 1h43:A, 1h44:A, 1h45:A, 1hse:A, 7jrd:B, 1lcf:A, 1lct:A, 1lfg:A, 1lfi:A, 1n76:A, 7n88:B, 2pms:A, 2pms:B, 1sqy:A, 1vfd:A, 1vfe:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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