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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGEHFNQAIEEWSVEK
HTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEIILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIK
AAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLH
SHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAA
DLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQSEAVHLFQTMMECMKKKELITVFHIGSEDHQDIDVAILTALLKG
TNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVSFVKLLIENGVSMHKFLTIPRLEELYNTKQ
GPTNPMLFHLIRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLETKRFPYPLNELLIWACLMKRQ
VMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKN
WSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILMLEYKTKAEMSHIPQSQLPITRK
FYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVKMEQLPSVQEWIVIAYIFTYAIEKVREVFMSEAGKISQKIKVWFSDYF
NVSDTIAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIV
VIMALVLLSFGVPRKAILYPHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAVYLFVQ
YIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCVCKGPKLFLTEEDQKKLHDF
EEQCVEMYFDEKDDKFNSGSEERIRVTFERVEQMSIQIKEVGDRVNYIKRSLQSLDS

The query sequence (length=1097) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8si6:A 1107 1107 1.0000 0.9910 0.9910 0.0 8si2:A, 8si2:B, 8si2:D, 8si2:C, 8si3:A, 8si3:B, 8si3:C, 8si3:D, 8si4:A, 8si4:B, 8si4:C, 8si4:D, 8si5:A, 8si5:B, 8si5:D, 8si5:C, 8si6:B, 8si6:C, 8si6:D, 8si7:A, 8si7:B, 8si7:D, 8si7:C, 8si8:A, 8si8:B, 8si8:D, 8si8:C, 8sia:A, 8sia:D, 8sia:B, 8sia:C, 8w2l:A, 8w2l:B, 8w2l:C, 8w2l:D
2 5zx5:B 814 839 0.6882 0.9275 0.8999 0.0 5zx5:D, 5zx5:A, 5zx5:C
3 5zx5:B 814 23 0.0210 0.0283 1.0000 1.45e-05 5zx5:D, 5zx5:A, 5zx5:C
4 5zx5:B 814 89 0.0310 0.0418 0.3820 0.027 5zx5:D, 5zx5:A, 5zx5:C
5 8ddr:A 968 1009 0.5971 0.6767 0.6492 0.0 8ddq:A, 8ddq:B, 8ddq:C, 8ddq:D, 8ddr:B, 8ddr:C, 8ddr:D, 8dds:A, 8dds:B, 8dds:C, 8dds:D, 8ddt:A, 8ddt:B, 8ddt:C, 8ddt:D, 8ddu:A, 8ddu:B, 8ddu:C, 8ddu:D, 8ddv:A, 8ddv:B, 8ddv:C, 8ddv:D, 8ddx:A, 8ddx:B, 8ddx:C, 8ed7:A, 8ed7:B, 8ed7:C, 8ed7:D, 8ed8:A, 8ed8:B, 8ed8:C, 8ed8:D, 8ed9:A, 8ed9:B, 8ed9:C, 8ed9:D
6 8ddx:D 992 1031 0.5980 0.6613 0.6363 0.0
7 6bwd:A 771 685 0.5397 0.7678 0.8642 0.0 6bwd:B, 6bwd:D, 6bwd:C
8 8ddw:A 695 594 0.3783 0.5971 0.6987 0.0 8ddw:B, 8ddw:C
9 8ddw:A 695 122 0.0565 0.0892 0.5082 2.02e-31 8ddw:B, 8ddw:C
10 8ddw:D 719 615 0.3792 0.5786 0.6764 0.0
11 8ddw:D 719 139 0.0583 0.0890 0.4604 1.48e-31
12 8ddw:D 719 24 0.0119 0.0181 0.5417 7.2
13 6co7:A 1061 1061 0.3355 0.3468 0.3468 0.0 6co7:B, 6co7:C, 6co7:D
14 6puu:A 1309 1133 0.3282 0.2750 0.3177 8.91e-152 8e6t:A, 8e6t:B, 8e6t:C, 8e6t:D, 6pur:A, 6pur:B, 6pur:C, 6pur:D, 6pus:A, 6pus:C, 6pus:D, 6pus:B, 6puu:B, 6puu:C, 6puu:D
15 8e6q:A 1348 1157 0.3345 0.2723 0.3172 1.28e-151 8e6q:B, 8e6q:C, 8e6q:D, 8e6r:A, 8e6r:B, 8e6r:C, 8e6r:D, 8e6s:A, 8e6s:B, 8e6s:C, 8e6s:D, 8e6u:A, 8e6u:B, 8e6u:C, 8e6u:D, 6mj2:A, 6mj2:B, 6mj2:C, 6mj2:D
16 6d73:A 1227 984 0.2799 0.2502 0.3120 1.38e-148 6d73:C, 6pkx:B, 6pkx:D
17 6drj:A 1266 980 0.2808 0.2433 0.3143 3.13e-147 6d73:B, 6d73:D, 6drj:B, 6drj:C, 6drj:D
18 6bcq:B 983 1053 0.2981 0.3327 0.3105 2.60e-136 6bco:B, 6bco:D, 6bco:A, 6bco:C, 6bcq:D, 6bcq:A, 6bcq:C
19 7mbp:A 996 1024 0.2817 0.3102 0.3018 4.19e-135 7mbp:B, 7mbp:C, 7mbp:D, 7mbq:A, 7mbq:B, 7mbq:C, 7mbq:D, 7mbr:A, 7mbr:B, 7mbr:C, 7mbr:D, 7mbs:A, 7mbs:B, 7mbs:C, 7mbs:D, 7mbt:A, 7mbt:D, 7mbt:B, 7mbt:C, 7mbu:A, 7mbu:D, 7mbu:B, 7mbu:C, 7mbv:A, 7mbv:B, 7mbv:C, 7mbv:D
20 9b8w:A 993 1119 0.2963 0.3273 0.2904 4.89e-133 9b8w:B, 9b8w:C, 9b8w:D, 9b8x:A, 9b8y:A, 9b8y:B, 9b8y:C, 9b8y:D, 9b8z:A, 9b90:A, 9b90:B, 9b90:C, 9b90:D, 9b91:A, 9b92:A, 9b92:B, 9b92:C, 9b92:D, 9b94:A, 9b94:B, 9b94:C, 9b94:D, 6bqr:A, 6bqr:C, 6bqr:B, 6bqr:D
21 8bdc:A 963 1024 0.2616 0.2980 0.2803 3.88e-130 8bdc:B, 8bdc:C, 8bdc:D
22 8slw:A 921 999 0.2698 0.3214 0.2963 3.64e-128 8slp:D, 8slp:A, 8slp:B, 8slp:C, 8slw:B, 8slw:C, 8slw:D
23 5wp6:A 977 1052 0.2780 0.3122 0.2899 5.28e-127 6bqv:A, 6bqv:C, 6bqv:B, 6bqv:D, 5wp6:B, 5wp6:C, 5wp6:D
24 8e4n:A 901 1015 0.2516 0.3063 0.2719 6.29e-122 9b6j:A, 9b6j:B, 9b6j:C, 9b6j:D, 8e4l:A, 8e4l:B, 8e4l:C, 8e4l:D, 8e4m:A, 8e4m:B, 8e4m:C, 8e4m:D, 8e4n:B, 8e4n:C, 8e4n:D, 8e4o:A, 8e4o:D, 8e4o:B, 8e4o:C, 8e4p:A, 8e4p:B, 8e4p:C, 8e4p:D
25 9b6h:B 934 1028 0.2552 0.2998 0.2724 2.87e-121 9b6d:A, 9b6d:B, 9b6d:C, 9b6d:D, 9b6e:B, 9b6e:A, 9b6e:C, 9b6e:D, 9b6f:A, 9b6f:B, 9b6f:C, 9b6f:D, 9b6g:A, 9b6g:B, 9b6g:C, 9b6g:D, 9b6h:A, 9b6h:C, 9b6h:D, 9b6k:A, 9b6k:B, 9b6k:C, 9b6k:D, 7wrb:A, 7wrb:B, 7wrb:C, 7wrb:D, 7wrc:A, 7wrc:B, 7wrc:C, 7wrc:D, 7wrd:A, 7wrd:B, 7wrd:C, 7wrd:D, 7wre:A, 7wre:B, 7wre:C, 7wre:D, 7wrf:A, 7wrf:B, 7wrf:C, 7wrf:D
26 8sli:A 894 999 0.2698 0.3311 0.2963 6.19e-115 8sli:D, 8sli:C, 8sli:B
27 6o72:A 858 995 0.2461 0.3147 0.2714 7.28e-112 6o72:B, 6o72:C, 6o72:D
28 6o77:A 872 943 0.2343 0.2947 0.2725 4.30e-110 9b6i:A, 9b6i:B, 9b6i:C, 9b6i:D, 6o77:D, 6o77:B, 6o77:C
29 6nr2:A 859 960 0.2379 0.3038 0.2719 1.01e-101 6nr2:B, 6nr2:C, 6nr2:D, 6nr3:A, 6nr3:B, 6nr3:C, 6nr3:D, 6o6a:A, 6o6a:B, 6o6a:C, 6o6a:D, 6o6r:A, 6o6r:B, 6o6r:C, 6o6r:D
30 8sr8:A 1353 1056 0.2370 0.1922 0.2462 9.45e-97 8sr8:B, 8sr8:C, 8sr8:D, 8sr9:A, 8sr9:B, 8sr9:C, 8sr9:D, 8sra:A, 8sra:B, 8sra:C, 8sra:D, 8srb:A, 8srb:B, 8srb:C, 8srb:D
31 8sre:A 1377 1056 0.2370 0.1888 0.2462 1.07e-96 8sr7:A, 8sr7:B, 8sr7:C, 8sr7:D, 8src:A, 8src:B, 8src:C, 8src:D, 8srd:A, 8srd:B, 8srd:C, 8srd:D, 8sre:B, 8sre:D, 8sre:C, 8srf:A, 8srf:B, 8srf:C, 8srf:D, 8srg:A, 8srg:B, 8srg:C, 8srg:D, 8srh:A, 8srh:B, 8srh:C, 8srh:D, 8sri:A, 8sri:B, 8sri:C, 8sri:D, 8srj:A, 8srj:B, 8srj:D, 8srj:C, 8srk:A, 8srk:B, 8srk:C, 8srk:D
32 8e6v:A 707 484 0.1632 0.2532 0.3698 3.39e-84
33 7aov:A 377 409 0.1322 0.3846 0.3545 3.87e-65 7aov:B
34 6bwi:A 816 705 0.1696 0.2279 0.2638 4.43e-61 6bwi:D, 6bwi:B, 6bwi:C
35 8gvw:A 671 460 0.1012 0.1654 0.2413 5.62e-18 6aei:A, 6aei:D, 6aei:B, 6aei:C, 7d4p:A, 7d4p:D, 7d4p:B, 7d4p:C, 7d4q:A, 7d4q:D, 7d4q:B, 7d4q:C, 7e4t:A, 7e4t:D, 7e4t:B, 7e4t:C, 8gvw:D, 8gvw:B, 8gvw:C, 7wdb:A, 7wdb:D, 7wdb:B, 7wdb:C
36 7b0j:A 682 485 0.1012 0.1628 0.2289 2.75e-17 7b0j:B, 7b0j:C, 7b0j:D
37 7b1g:A 691 483 0.1003 0.1592 0.2277 3.15e-17 7b05:A, 7b05:D, 7b05:B, 7b05:C, 7b0s:A, 7b0s:D, 7b0s:B, 7b0s:C, 7b16:A, 7b16:B, 7b16:C, 7b16:D, 7b1g:C, 7b1g:B, 7b1g:D, 6g1k:A, 6g1k:B, 6g1k:D, 6g1k:C
38 7x6i:A 687 462 0.0985 0.1572 0.2338 1.01e-16 8gvx:B, 8gvx:A, 8gvx:D, 8gvx:C, 7x6c:C, 7x6c:B, 7x6c:A, 7x6c:D, 7x6i:D, 7x6i:B, 7x6i:C, 6ysn:A, 6ysn:B, 6ysn:C, 6ysn:D
39 5z96:A 670 451 0.0930 0.1522 0.2262 2.61e-16 6jzo:A, 6jzo:D, 6jzo:B, 6jzo:C, 5z96:D, 5z96:B, 5z96:C
40 6uz8:A 734 498 0.0893 0.1335 0.1968 3.40e-08 6uz8:D, 6uz8:C, 6uz8:B, 6uza:A, 6uza:B, 6uza:C, 6uza:D
41 7dxg:A 698 451 0.0848 0.1332 0.2062 5.78e-08 7dxf:A, 7dxf:D, 7dxf:B, 7dxf:C, 7dxg:D, 7dxg:C, 7dxg:B
42 7dxb:A 738 175 0.0337 0.0501 0.2114 5.82e-07 6cud:A, 6cud:D, 6cud:B, 6cud:C, 7dxb:D, 7dxb:B, 7dxb:C, 7dxc:A, 7dxc:B, 7dxc:D, 7dxc:C, 7dxd:A, 7dxd:B, 7dxd:C, 7dxd:D, 7dxe:D, 7dxe:A, 7dxe:B, 7dxe:C
43 7k4e:B 620 139 0.0310 0.0548 0.2446 0.093 7d2k:A, 6d7o:A, 6d7p:A, 6d7q:A, 6d7t:A, 6d7t:B, 6d7t:C, 6d7t:D, 6d7v:A, 6d7x:A, 8foa:A, 8foa:B, 8foa:D, 8foa:C, 8fob:A, 8fob:D, 8fob:B, 8fob:C, 5iwk:A, 5iwr:A, 5iwt:A, 7k4a:A, 7k4a:D, 7k4a:B, 7k4a:C, 7k4b:A, 7k4b:B, 7k4b:D, 7k4b:C, 7k4c:A, 7k4c:B, 7k4c:C, 7k4c:D, 7k4d:A, 7k4d:B, 7k4d:C, 7k4d:D, 7k4e:C, 7k4e:D, 7k4f:A, 7k4f:B, 7k4f:C, 7k4f:D, 7s88:A, 7s88:B, 7s88:C, 7s88:D, 7s89:A, 7s89:D, 7s89:B, 7s89:C, 7s8b:A, 7s8b:B, 7s8b:D, 7s8b:C, 7s8c:A, 7s8c:B, 7s8c:C, 7s8c:D, 8sp8:A, 8sp8:B, 8sp8:C, 8sp8:D, 5wo6:A, 5wo7:A, 5wo9:A
44 8jvi:B 604 303 0.0547 0.0993 0.1980 0.33 8fca:A, 8fca:B, 8fca:C, 8fca:D, 8j1b:A, 8j1b:B, 8j1b:C, 8j1b:D, 8j1f:A, 8j1f:B, 8j1f:C, 8j1f:D, 8j1h:C, 8j1h:D, 8j1h:B, 8j1h:A, 8jvi:C, 8jvi:D, 8jvi:A
45 8v6l:A 653 212 0.0401 0.0674 0.2075 0.59 6dvy:A, 6dvy:B, 6dvy:C, 6dvy:D, 6dvz:A, 6dvz:B, 6dvz:C, 6dvz:D, 7ugg:A, 7ugg:D, 7ugg:B, 7ugg:C, 8v6l:B, 8v6l:C, 8v6l:D, 8v6m:A, 8v6m:B, 8v6m:C, 8v6m:D, 8v6n:A, 8v6n:B, 8v6n:C, 8v6n:D, 8v6o:A, 8v6o:B, 8v6o:C, 8v6o:D, 7xj1:C, 7xj1:A
46 8fhi:A 610 139 0.0301 0.0541 0.2374 0.63 6dmu:A, 6dmu:B, 6dmu:C, 6dmu:D, 8ffn:A, 8ffn:B, 8ffn:C, 8ffn:D, 8ffo:A, 8ffo:D, 8ffo:B, 8ffo:C, 8ffq:A, 8ffq:B, 8ffq:C, 8ffq:D, 8fhh:A, 8fhh:B, 8fhh:C, 8fhh:D, 8fhi:B, 8fhi:C, 8fhi:D, 6pbe:A, 6pbe:B, 6pbe:C, 6pbe:D, 6pbf:A, 6pbf:B, 6pbf:D, 6pbf:C, 7t6m:A, 7t6m:B, 7t6m:C, 7t6m:D, 7t6q:A, 7t6q:B, 7t6q:C, 7t6q:D, 8tf2:A, 8tf2:D, 8tf2:B, 8tf2:C, 8tf3:A, 8tf3:D, 8tf3:B, 8tf3:C, 8tf4:A, 8tf4:D, 8tf4:B, 8tf4:C
47 6b5v:A 589 139 0.0301 0.0560 0.2374 0.79 6b5v:B, 6b5v:D, 6b5v:C
48 6ot5:A 623 220 0.0428 0.0754 0.2136 0.86 6ot5:B, 6ot5:C, 6ot5:D, 7ras:A, 7ras:B, 7ras:C, 7ras:D, 7rau:A, 7rau:B, 7rau:C, 7rau:D, 6uw4:A, 6uw4:D, 6uw4:B, 6uw4:C, 6uw6:A, 6uw6:D, 6uw6:B, 6uw6:C, 7xj0:B, 7xj0:A, 7xj0:C, 7xj0:D, 7xj1:B, 7xj1:D, 7xj2:B, 7xj2:C, 7xj2:D, 7xj2:A
49 6y01:DDD 166 75 0.0246 0.1627 0.3600 2.1 6y01:AAA, 6y01:BBB, 6y01:CCC
50 7ane:am 272 92 0.0173 0.0699 0.2065 2.8
51 5ifp:A 968 20 0.0109 0.0124 0.6000 3.1 5ift:A, 5ihr:A, 5juv:A, 5mgc:A, 5mgd:A
52 4dns:A 486 59 0.0128 0.0288 0.2373 5.5 4dns:B
53 4bjk:A 450 69 0.0173 0.0422 0.2754 5.7 4bjk:B, 4bjk:C, 4bjk:D, 3g1q:A, 3g1q:B, 3g1q:C, 3g1q:D, 4g3j:A, 4g3j:B, 4g3j:C, 4g3j:D, 4g7g:A, 4g7g:B, 4g7g:C, 4g7g:D, 3gw9:A, 3gw9:B, 3gw9:C, 3gw9:D, 3p99:A, 3p99:B, 3p99:C, 3p99:D, 3tik:A, 3tik:B, 3tik:C, 3tik:D, 2wv2:A, 2x2n:A, 2x2n:B, 2x2n:C, 2x2n:D
54 3b03:B 364 42 0.0137 0.0412 0.3571 8.6 3b03:A, 3b03:C, 3b03:D, 3b04:A, 3b04:B, 3b04:C, 3b04:D, 3b05:A, 3b05:B, 3b05:C, 3b05:D, 3b06:A, 3b06:B, 3b06:C, 3b06:D, 3vkj:A, 3vkj:B, 3vkj:C, 3vkj:D, 2zru:A, 2zru:B, 2zru:C, 2zru:D, 2zrv:A, 2zrv:B, 2zrv:C, 2zrv:D, 2zrw:A, 2zrw:B, 2zrw:C, 2zrw:D, 2zrx:A, 2zrx:B, 2zrx:C, 2zrx:D, 2zry:A, 2zry:B, 2zry:C, 2zry:D, 2zrz:A, 2zrz:B, 2zrz:C, 2zrz:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218