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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QKINPYRSHMKQKFQVLWEKEPCLLVPEDFYEETTKIEYELLSTVYLDAESSPTVVLHGPEGIGKTTFLRKVMLEWAKGN
LWRDRFSFVFFLTGREMNGVTDMSLVELLSRDWPESSEPIEDIFSQPERILFILDGMEELKFDLDCNADLCEDWEQPQSM
QVVLQSLLQKQMLPECSLLLALSKMGMRKNYSLLKHMKCIFLLGFSEHQRKLYFSHYFQEKDASSRAFSFVREKSSLFVL
CQSPFLCWLVCTSLKCQLEKGEDLELDSETITGLYVSFFTKVFRSGSETCPLKQRRARLKSLCTLAAEGMWTCTFLFCPE
DLRRNGVSESDTSMWLDMKLLHRSGDCLAFIHTCIQEFCAAMFYMFTRPKDPPHSVIGNVTQLITRAVSGHYSRLSWTAV
FLFVFSTERMTHRLETSFGFPLSKEIKQEITQSLDTLSQCDPNNVMMSFQALFNCLFETQDPEFVAQVVNFFKDIDIYIG
TKEELIICAACLRHCHSLQKFHLCMEHVFPDESGCISNTIEKLTLWRDVCSAFAASEDFEILNLDNCRFDEPSLAVLCRT
LSQPVCKLRKFVCNFASNLANSLELFKVILHNPHLKHLNFYGSSLSHMDARQLCEALKHPMCNIEELMLGKCDITGEACE
DIASVLVHNKKLNLLSLCENALKDDGVLVLCEALKNPDCALEALLLSHCCFSSAACDHLSQVLLYNRSLTFLDLGSNVLK
DEGVTTLCESLKHPSCNLQELWLMNCYFTSVCCVDIATVLIHSEKLKTLKLGNNKIYDAGAKQLCKALKHPKCKLENLGL
EACELSPASCEDLASALTTCKSLTCVNLEWITLDYDGAAVLCEALVSLECSLQLLGLNKSSYDEEIKMMLTQVEEMNPNL
IISHHLWTDDEGRRRGILV

The query sequence (length=899) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7wbt:A 899 899 1.0000 1.0000 1.0000 0.0 7wbt:B, 7wbu:A
2 7pzc:A 1010 853 0.3404 0.3030 0.3587 3.35e-158 7pzc:B, 7pzc:C, 7pzc:D, 7pzc:E, 7pzc:F, 7pzc:G, 7pzc:H, 7pzc:I, 7pzc:J
3 8ej4:A 850 764 0.3126 0.3306 0.3678 1.72e-154 8ej4:B, 8ej4:C, 8ej4:D, 8ej4:E, 8ej4:F, 8ej4:G, 8ej4:H, 8ej4:I, 8ej4:J, 8etr:A, 8ri2:A, 8swk:A, 8swk:B, 8swk:C, 8swk:D, 8swk:E, 8swk:F, 8sxn:C, 8sxn:D, 7zgu:A, 7zgu:B, 7zgu:C, 7zgu:D, 7zgu:E, 7zgu:F
4 8ej4:A 850 298 0.1402 0.1482 0.4228 5.20e-57 8ej4:B, 8ej4:C, 8ej4:D, 8ej4:E, 8ej4:F, 8ej4:G, 8ej4:H, 8ej4:I, 8ej4:J, 8etr:A, 8ri2:A, 8swk:A, 8swk:B, 8swk:C, 8swk:D, 8swk:E, 8swk:F, 8sxn:C, 8sxn:D, 7zgu:A, 7zgu:B, 7zgu:C, 7zgu:D, 7zgu:E, 7zgu:F
5 8ej4:A 850 235 0.1079 0.1141 0.4128 5.65e-41 8ej4:B, 8ej4:C, 8ej4:D, 8ej4:E, 8ej4:F, 8ej4:G, 8ej4:H, 8ej4:I, 8ej4:J, 8etr:A, 8ri2:A, 8swk:A, 8swk:B, 8swk:C, 8swk:D, 8swk:E, 8swk:F, 8sxn:C, 8sxn:D, 7zgu:A, 7zgu:B, 7zgu:C, 7zgu:D, 7zgu:E, 7zgu:F
6 8ej4:A 850 189 0.0890 0.0941 0.4233 9.94e-32 8ej4:B, 8ej4:C, 8ej4:D, 8ej4:E, 8ej4:F, 8ej4:G, 8ej4:H, 8ej4:I, 8ej4:J, 8etr:A, 8ri2:A, 8swk:A, 8swk:B, 8swk:C, 8swk:D, 8swk:E, 8swk:F, 8sxn:C, 8sxn:D, 7zgu:A, 7zgu:B, 7zgu:C, 7zgu:D, 7zgu:E, 7zgu:F
7 8ej4:A 850 72 0.0256 0.0271 0.3194 3.0 8ej4:B, 8ej4:C, 8ej4:D, 8ej4:E, 8ej4:F, 8ej4:G, 8ej4:H, 8ej4:I, 8ej4:J, 8etr:A, 8ri2:A, 8swk:A, 8swk:B, 8swk:C, 8swk:D, 8swk:E, 8swk:F, 8sxn:C, 8sxn:D, 7zgu:A, 7zgu:B, 7zgu:C, 7zgu:D, 7zgu:E, 7zgu:F
8 7vtp:A 795 804 0.3181 0.3597 0.3557 6.94e-149 7alv:A, 7vtp:B, 7vtp:C, 7vtp:D, 7vtp:E, 7vtp:F, 8wsm:A
9 7vtp:A 795 298 0.1402 0.1585 0.4228 3.10e-57 7alv:A, 7vtp:B, 7vtp:C, 7vtp:D, 7vtp:E, 7vtp:F, 8wsm:A
10 7vtp:A 795 236 0.1079 0.1220 0.4110 4.12e-41 7alv:A, 7vtp:B, 7vtp:C, 7vtp:D, 7vtp:E, 7vtp:F, 8wsm:A
11 7vtp:A 795 189 0.0890 0.1006 0.4233 8.38e-32 7alv:A, 7vtp:B, 7vtp:C, 7vtp:D, 7vtp:E, 7vtp:F, 8wsm:A
12 7vtp:A 795 72 0.0256 0.0289 0.3194 2.9 7alv:A, 7vtp:B, 7vtp:C, 7vtp:D, 7vtp:E, 7vtp:F, 8wsm:A
13 6npy:A 798 810 0.3148 0.3546 0.3494 2.33e-141
14 6npy:A 798 298 0.1402 0.1579 0.4228 3.21e-57
15 6npy:A 798 225 0.1034 0.1165 0.4133 4.19e-41
16 6npy:A 798 198 0.0923 0.1040 0.4192 5.96e-32
17 6npy:A 798 83 0.0289 0.0326 0.3133 0.25
18 7vtq:A 789 801 0.2925 0.3333 0.3283 7.01e-137 7vtq:B, 7vtq:C, 7vtq:D, 7vtq:E, 7vtq:F, 7vtq:G, 7vtq:H, 7vtq:I, 7vtq:J, 7vtq:K, 7vtq:L
19 7vtq:A 789 298 0.1379 0.1572 0.4161 4.03e-55 7vtq:B, 7vtq:C, 7vtq:D, 7vtq:E, 7vtq:F, 7vtq:G, 7vtq:H, 7vtq:I, 7vtq:J, 7vtq:K, 7vtq:L
20 7vtq:A 789 227 0.1023 0.1166 0.4053 4.32e-40 7vtq:B, 7vtq:C, 7vtq:D, 7vtq:E, 7vtq:F, 7vtq:G, 7vtq:H, 7vtq:I, 7vtq:J, 7vtq:K, 7vtq:L
21 7vtq:A 789 167 0.0523 0.0596 0.2814 1.17e-09 7vtq:B, 7vtq:C, 7vtq:D, 7vtq:E, 7vtq:F, 7vtq:G, 7vtq:H, 7vtq:I, 7vtq:J, 7vtq:K, 7vtq:L
22 7vtq:A 789 109 0.0345 0.0393 0.2844 0.001 7vtq:B, 7vtq:C, 7vtq:D, 7vtq:E, 7vtq:F, 7vtq:G, 7vtq:H, 7vtq:I, 7vtq:J, 7vtq:K, 7vtq:L
23 7wge:A 698 702 0.2436 0.3138 0.3120 1.26e-90
24 7wge:A 698 173 0.0823 0.1060 0.4277 2.00e-31
25 7wge:A 698 181 0.0790 0.1017 0.3923 8.05e-29
26 2bex:B 457 320 0.1179 0.2319 0.3312 2.46e-41
27 2bex:B 457 342 0.1257 0.2473 0.3304 3.87e-41
28 2bex:B 457 271 0.1034 0.2035 0.3432 1.77e-38
29 5irm:C 770 772 0.2125 0.2481 0.2474 1.20e-23 5irl:A, 5irm:A, 5irn:A
30 5irm:C 770 256 0.0801 0.0935 0.2812 3.40e-09 5irl:A, 5irm:A, 5irn:A
31 5irm:C 770 231 0.0745 0.0870 0.2900 5.06e-07 5irl:A, 5irm:A, 5irn:A
32 4r6g:A 464 143 0.0601 0.1164 0.3776 1.44e-18
33 4r6g:A 464 173 0.0645 0.1250 0.3353 3.65e-18
34 4r6g:A 464 150 0.0590 0.1142 0.3533 4.10e-13
35 4r6g:A 464 183 0.0690 0.1336 0.3388 9.59e-13
36 4kxf:K 904 828 0.2013 0.2002 0.2186 2.51e-08 4kxf:B, 4kxf:D, 4kxf:F, 4kxf:H, 4kxf:L, 4kxf:N
37 4kxf:K 904 120 0.0367 0.0365 0.2750 0.69 4kxf:B, 4kxf:D, 4kxf:F, 4kxf:H, 4kxf:L, 4kxf:N
38 4kxf:P 866 818 0.2013 0.2090 0.2213 3.53e-07
39 4kxf:P 866 120 0.0367 0.0381 0.2750 0.74
40 8fvu:A 1361 315 0.0812 0.0536 0.2317 8.45e-07 2vm5:A
41 5yud:A 1238 317 0.0834 0.0606 0.2366 1.16e-04
42 7rav:A 773 317 0.0834 0.0970 0.2366 1.35e-04
43 3j0a:B 632 128 0.0456 0.0649 0.3203 0.23
44 4k17:B 660 100 0.0323 0.0439 0.2900 0.32 4k17:C
45 4k17:B 660 142 0.0400 0.0545 0.2535 1.3 4k17:C
46 2qor:A 196 53 0.0222 0.1020 0.3774 0.45
47 8c0v:A 823 86 0.0222 0.0243 0.2326 1.2 8c0v:C, 8c0v:E, 8c0w:B, 8c0w:D, 8c0w:F, 8u0v:A, 8u0v:C, 8u0v:E
48 5b43:A 1272 87 0.0323 0.0228 0.3333 1.4
49 5kk5:A 1201 87 0.0323 0.0241 0.3333 1.5
50 4qbz:A 754 59 0.0256 0.0305 0.3898 1.6 5awa:A, 5awb:A, 5awc:A, 5awc:B, 5awc:C, 5awc:D, 5awd:A, 5az5:A, 5az5:B, 5az5:C, 5az5:D, 7crf:A, 7crf:B, 6kya:A, 6kya:B, 4qbz:B, 4qc0:A, 4qc0:B, 4r07:A, 4r07:B, 4r07:C, 4r07:D, 4r08:A, 4r08:B, 4r08:C, 4r08:D, 4r09:A, 4r09:B, 4r09:C, 4r09:D, 4r0a:A, 7r52:B, 7r53:A, 7r53:B, 7r54:A, 7r54:B, 4r6a:A, 4r6a:B, 7rc9:A, 7rc9:B, 6ty5:A, 6ty5:B, 6v9u:A, 6v9u:B, 3w3g:A, 3w3j:A, 3w3j:B, 3w3k:A, 3w3k:B, 3w3l:A, 3w3l:B, 3w3l:D, 3w3l:C, 3w3m:A, 3w3n:A, 3w3n:B, 6wml:A, 6wml:B, 6wml:C, 6wml:D, 3wn4:A, 5wyx:A, 5wyx:B, 5wyz:A, 5wyz:B, 7ytx:A, 7ytx:B, 5z14:A, 5z14:B, 5z15:A, 5z15:B, 6zjz:A, 6zjz:B
51 8pfi:B 734 59 0.0256 0.0313 0.3898 1.6 8pfi:A, 7r52:A
52 2fsn:B 311 40 0.0156 0.0450 0.3500 1.9 2fsn:A
53 6tvo:A 1011 146 0.0389 0.0346 0.2397 2.2 2l1l:B
54 4ymu:J 240 47 0.0211 0.0792 0.4043 2.4 4ymu:A, 4ymv:J, 4ymv:A
55 1ex7:A 186 53 0.0211 0.1022 0.3585 2.7 1gky:A
56 4z63:A 610 39 0.0211 0.0311 0.4872 3.2 4z64:A
57 8sfo:A 1240 87 0.0311 0.0226 0.3218 3.4 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
58 8sfn:A 1302 87 0.0311 0.0215 0.3218 3.8 8sfh:A, 8sfl:A, 5xh6:A, 5xh7:A
59 3rgz:A 745 202 0.0578 0.0698 0.2574 5.2 4lsa:A, 4lsx:A, 4lsx:B, 4m7e:A, 4m7e:B, 3rj0:A
60 4b3g:A 614 26 0.0122 0.0179 0.4231 5.6 4b3g:B
61 5vc7:A 544 83 0.0289 0.0478 0.3133 7.6 5vc7:C, 5vc7:D, 5vc7:E, 5vc7:F, 5vc7:G
62 2p1n:B 571 207 0.0567 0.0893 0.2464 8.2 3c6n:B, 3c6o:B, 3c6p:B, 2p1m:B, 2p1n:E, 2p1o:B, 2p1p:B, 2p1q:B
63 5euf:B 416 48 0.0189 0.0409 0.3542 9.3 5euf:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218