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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QGWQKLSHEEIILQVNSSTAADTIQTIPIIPRLSVPAGDKPIYSGSAPHLRTIGSAFAIHRWRALSFEWIPSCPTTTPGN
LVLRFYPNYSTETPKTLTDLMDSESLVLVPSLSGKTYRPKIETRGNPPELRNIDATAFSALSDEDKGDYSVGRLVVGSSK
QAVVIQLGLLRMRYSAEMRGATSIS

The query sequence (length=185) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4v99:GW 217 185 1.0000 0.8525 1.0000 4.54e-136 4v99:AA, 4v99:EV, 4v99:AF, 4v99:A5, 4v99:AK, 4v99:Da, 4v99:AP, 4v99:Ba, 4v99:AU, 4v99:Ca, 4v99:AZ, 4v99:Dz, 4v99:Ae, 4v99:Bk, 4v99:Aj, 4v99:Ez, 4v99:Ao, 4v99:DL, 4v99:AG, 4v99:At, 4v99:Ay, 4v99:EL, 4v99:A4, 4v99:BQ, 4v99:BA, 4v99:Bu, 4v99:Au, 4v99:BF, 4v99:BK, 4v99:Ck, 4v99:BG, 4v99:BP, 4v99:AV, 4v99:BU, 4v99:BZ, 4v99:D5, 4v99:AQ, 4v99:Be, 4v99:Bj, 4v99:E5, 4v99:BL, 4v99:Bo, 4v99:Bt, 4v99:DV, 4v99:By, 4v99:Cp, 4v99:B4, 4v99:Df, 4v99:CA, 4v99:DG, 4v99:CF, 4v99:Cz, 4v99:CB, 4v99:CK, 4v99:CP, 4v99:EG, 4v99:BB, 4v99:CU, 4v99:CZ, 4v99:DQ, 4v99:Af, 4v99:Ce, 4v99:Cj, 4v99:EQ, 4v99:Co, 4v99:Du, 4v99:CQ, 4v99:Ct, 4v99:Cy, 4v99:Eu, 4v99:B5, 4v99:C4, 4v99:Bp, 4v99:DA, 4v99:AL, 4v99:DF, 4v99:Bz, 4v99:DK, 4v99:DP, 4v99:Ep, 4v99:DU, 4v99:Dp, 4v99:CL, 4v99:DZ, 4v99:Az, 4v99:De, 4v99:Cf, 4v99:Dj, 4v99:CV, 4v99:Do, 4v99:Ap, 4v99:Dt, 4v99:CG, 4v99:Dy, 4v99:D4, 4v99:EB, 4v99:Bf, 4v99:EA, 4v99:Ak, 4v99:EF, 4v99:C5, 4v99:EK, 4v99:DB, 4v99:EP, 4v99:EU, 4v99:Ea, 4v99:EZ, 4v99:Ef, 4v99:Ee, 4v99:Ek, 4v99:AB, 4v99:Ej, 4v99:BV, 4v99:Eo, 4v99:Aa, 4v99:Et, 4v99:Cu, 4v99:Ey, 4v99:Dk, 4v99:E4, 4v99:FA, 4v99:JV, 4v99:FF, 4v99:F5, 4v99:FK, 4v99:Ia, 4v99:FP, 4v99:Ga, 4v99:FU, 4v99:Ha, 4v99:FZ, 4v99:Iz, 4v99:Fe, 4v99:Gk, 4v99:Fj, 4v99:Jz, 4v99:Fo, 4v99:IL, 4v99:FG, 4v99:Ft, 4v99:Fy, 4v99:JL, 4v99:F4, 4v99:GQ, 4v99:GA, 4v99:Gu, 4v99:Fu, 4v99:GF, 4v99:GK, 4v99:Hk, 4v99:GG, 4v99:GP, 4v99:FV, 4v99:GU, 4v99:GZ, 4v99:I5, 4v99:FQ, 4v99:Ge, 4v99:Gj, 4v99:J5, 4v99:GL, 4v99:Go, 4v99:Gt, 4v99:IV, 4v99:Gy, 4v99:G4, 4v99:If, 4v99:HA, 4v99:IG, 4v99:HF, 4v99:Hz, 4v99:HB, 4v99:HK, 4v99:HP, 4v99:JG, 4v99:GB, 4v99:HU, 4v99:HZ, 4v99:IQ, 4v99:Ff, 4v99:He, 4v99:Hj, 4v99:JQ, 4v99:Ho, 4v99:Iu, 4v99:HQ, 4v99:Ht, 4v99:Hy, 4v99:Ju, 4v99:G5, 4v99:H4, 4v99:Gp, 4v99:IA, 4v99:FL, 4v99:IF, 4v99:Gz, 4v99:IK, 4v99:IP, 4v99:Jp, 4v99:IU, 4v99:Ip, 4v99:HL, 4v99:IZ, 4v99:Fz, 4v99:Ie, 4v99:Hf, 4v99:Ij, 4v99:HV, 4v99:Io, 4v99:Fp, 4v99:It, 4v99:HG, 4v99:Iy, 4v99:I4, 4v99:JB, 4v99:Gf, 4v99:JA, 4v99:Fk, 4v99:JF, 4v99:H5, 4v99:JK, 4v99:IB, 4v99:JP, 4v99:JU, 4v99:Ja, 4v99:JZ, 4v99:Jf, 4v99:Je, 4v99:Jk, 4v99:FB, 4v99:Jj, 4v99:GV, 4v99:Jo, 4v99:Fa, 4v99:Jt, 4v99:Hu, 4v99:Jy, 4v99:Ik, 4v99:J4, 4v99:Hg
2 4sbv:C 222 67 0.0973 0.0811 0.2687 7.78e-04 4sbv:A, 4sbv:B
3 1c8n:C 219 147 0.1946 0.1644 0.2449 0.001 1c8n:A, 1c8n:B
4 1x33:C 225 53 0.0703 0.0578 0.2453 0.008 1smv:A, 1smv:B, 1smv:C, 1vak:A, 1vb4:A, 2vq0:A, 2vq0:C, 2vq0:B, 1x33:A, 1x33:B, 1x35:A, 1x35:B, 1x35:C, 1x36:A
5 4llf:D 321 38 0.0757 0.0436 0.3684 0.21 4llf:A, 4llf:B, 4llf:E, 4llf:G, 4llf:F, 4llf:H, 4llf:J, 4llf:I, 4llf:K, 4llf:M, 4llf:L, 4llf:N, 4llf:P, 4llf:O
6 1opo:C 268 55 0.0865 0.0597 0.2909 0.29 1opo:B
7 8yf8:C 305 73 0.1135 0.0689 0.2877 0.29 4rfu:A, 4rfu:B, 4rfu:C, 4wiz:BA, 4wiz:AA, 4wiz:CA, 4wiz:BB, 4wiz:AB, 4wiz:CB, 4wiz:BC, 4wiz:AC, 4wiz:CC, 4wiz:BD, 4wiz:AD, 4wiz:CD, 4wiz:BE, 4wiz:AE, 4wiz:CE, 4wiz:BF, 4wiz:AF, 4wiz:CF, 4wiz:BG, 4wiz:AG, 4wiz:CG, 4wiz:BH, 4wiz:AH, 4wiz:CH, 4wiz:BI, 4wiz:AI, 4wiz:CI, 4wiz:BJ, 4wiz:AJ, 4wiz:CJ, 4wiz:BK, 4wiz:AK, 4wiz:CK, 4wiz:BL, 4wiz:AL, 4wiz:CL, 4wiz:BM, 4wiz:AM, 4wiz:CM, 4wiz:BN, 4wiz:AN, 4wiz:CN, 4wiz:BO, 4wiz:AO, 4wiz:CO, 4wiz:BP, 4wiz:AP, 4wiz:CP, 4wiz:BQ, 4wiz:AQ, 4wiz:CQ, 4wiz:BR, 4wiz:AR, 4wiz:CR, 4wiz:BS, 4wiz:AS, 4wiz:CS, 4wiz:BT, 4wiz:AT, 4wiz:CT, 4wiz:BU, 4wiz:AU, 4wiz:CU, 4wiz:BV, 4wiz:AV, 4wiz:CV, 4wiz:BW, 4wiz:AW, 4wiz:CW, 4wiz:BX, 4wiz:AX, 4wiz:CX, 4wiz:BY, 4wiz:AY, 4wiz:CY, 4wiz:BZ, 4wiz:AZ, 4wiz:CZ, 4wiz:Ba, 4wiz:Aa, 4wiz:Ca, 4wiz:Bb, 4wiz:Ab, 4wiz:Cb, 4wiz:Bc, 4wiz:Ac, 4wiz:Cc, 4wiz:Bd, 4wiz:Ad, 4wiz:Cd, 8yf6:A, 8yf6:B, 8yf6:C, 8yf7:A, 8yf7:C, 8yf7:B, 8yf8:A, 8yf8:B, 8yf9:A, 8yf9:B, 8yf9:C
8 7cpx:A 2262 64 0.1027 0.0084 0.2969 0.91 7cpx:B, 7cpy:A, 7cpy:B
9 1ng0:C 218 55 0.0811 0.0688 0.2727 0.96 1ng0:A, 1ng0:B
10 3ww1:A 242 62 0.1135 0.0868 0.3387 1.1 3ww1:B, 3ww2:A, 3ww2:B, 3ww3:A, 3ww3:B, 3ww4:A, 3ww4:B
11 6mrl:D 326 34 0.0703 0.0399 0.3824 2.2 6mrl:A, 6mrl:B
12 8q3k:B 1020 41 0.0811 0.0147 0.3659 3.8
13 2tbv:C 321 79 0.1027 0.0592 0.2405 4.6 2tbv:A, 2tbv:B
14 6ahi:B 306 44 0.0811 0.0490 0.3409 5.0
15 7fhp:A 292 57 0.0919 0.0582 0.2982 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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