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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QFTDIDKLAVSTIRILAVDTVSKANSGHPGAPLGMAPAAHVLWSQMRMNPTNPDWINRDRFVLSNGHAVALLYSMLHLTG
YDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQE
GISSEASSLAGHLKLGNLIAIYDDNKITIDGATSISFDEDVAKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPT
LIKMTTTIGYGSLHAGSHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNKWNKLFSEYQKK
FPELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETVLEDVYNQLPELIGGSADLTPSNLTRWKEALDFQPPSS
GSGNYSGRYIRYGIREHAMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVGEDGPTHQ
PIETLAHFRSLPNIQVWRPADGNEVSAAYKNSLESKHTPSIIALSRQNLPQLEGSSIESASKGGYVLQDVANPDIILVAT
GSEVSLSVEAAKTLAAKNIKARVVSLPDFFTFDKQPLEYRLSVLPDNVPIMSVEVLATTCWGKYAHQSFGIDRFGASGKA
PEVFKFFGFTPEGVAERAQKTIAFYKGDKLISPLKKAF

The query sequence (length=678) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1ay0:A 678 678 0.9985 0.9985 0.9985 0.0 1ay0:B, 1gpu:A, 1gpu:B, 1ngs:A, 1ngs:B, 1tka:A, 1tka:B, 1tkb:A, 1tkb:B, 1tkc:A, 1tkc:B, 1trk:A, 1trk:B
2 5hje:A 676 677 0.6903 0.6923 0.6913 0.0 5hyv:A, 5i51:A, 5i5e:A, 5i5g:A, 5xps:A, 5xqa:A, 5xqk:A, 5xrv:A, 5xry:A, 5xs6:A, 5xsa:A, 5xsb:A, 5xsm:A, 5xt0:A, 5xt4:A, 5xtl:A, 5xtv:A, 5xtx:A, 5xu2:A, 5xu9:A, 5xuf:A, 5xvt:A
3 1r9j:B 671 664 0.5103 0.5156 0.5211 0.0 1r9j:A
4 5nd5:A 669 666 0.5103 0.5172 0.5195 0.0 5nd5:B
5 8ci0:AAA 666 662 0.5044 0.5135 0.5166 0.0 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
6 8cip:A 665 670 0.4867 0.4962 0.4925 0.0 8cip:B, 8cip:C, 8cip:D
7 8r3q:D 676 674 0.4853 0.4867 0.4881 0.0 8r3q:B, 8r3q:A, 8r3q:C
8 8r3p:A 672 666 0.4926 0.4970 0.5015 0.0 8r3p:B, 8r3p:C, 8r3p:D
9 3m49:A 665 670 0.4838 0.4932 0.4896 0.0 3hyl:A, 3hyl:B, 3m49:B
10 7wrr:A 650 655 0.4838 0.5046 0.5008 0.0 7wrr:B, 7wrr:C, 7wrr:D, 7wrt:A, 7wrt:B, 7wrt:C, 7wrt:D
11 8r3o:B 667 666 0.4838 0.4918 0.4925 0.0 8r3o:A, 8r3o:C, 8r3o:D
12 8qmf:A 678 671 0.4838 0.4838 0.4888 0.0 8qmf:B
13 4c7x:A 662 667 0.4676 0.4789 0.4753 0.0
14 5vrb:B 646 659 0.4631 0.4861 0.4765 0.0 5vrb:D
15 3upt:A 671 672 0.4882 0.4933 0.4926 0.0 3upt:B
16 5hht:B 667 670 0.4646 0.4723 0.4701 0.0 5hht:A, 1qgd:A, 1qgd:B, 2r5n:A, 2r5n:B, 2r8o:A, 2r8o:B, 2r8p:A, 2r8p:B, 6rjc:A, 6rjc:B, 6tj8:A, 6tj8:B, 6tj9:A, 6tj9:B, 8wa7:A, 8wa7:B
17 8r3s:A 663 664 0.4558 0.4661 0.4654 0.0 8r3s:B, 8r3s:C, 8r3s:D, 8r3s:E, 8r3s:F, 8r3s:G, 8r3s:H, 8r3s:I, 8r3s:J
18 5vrb:A 627 665 0.4513 0.4880 0.4602 0.0 5vrb:C
19 8r3r:A 658 663 0.4528 0.4666 0.4630 0.0 8r3r:B, 8r3r:C, 8r3r:D
20 4xeu:A 632 665 0.4558 0.4889 0.4647 0.0
21 3rim:A 694 675 0.4469 0.4366 0.4489 0.0 3rim:C, 3rim:B, 3rim:D
22 3m34:A 632 642 0.4248 0.4557 0.4486 4.00e-163 3m6l:A, 3m7i:A
23 6yak:AAA 282 283 0.1681 0.4043 0.4028 2.51e-47 6yak:CCC
24 6rjb:B 622 668 0.2640 0.2878 0.2680 8.63e-46 6ha3:A, 6had:A, 4kxu:A, 4kxv:A, 4kxw:A, 4kxx:A, 4kxy:A, 4kxy:B, 3mos:A, 3ooy:A, 3ooy:B, 6rjb:A, 8wa8:A, 8wa9:A, 8wa9:B, 8waa:A, 8waa:B
25 6yak:DDD 311 340 0.1431 0.3119 0.2853 5.97e-23 6yak:BBB
26 2o1s:B 493 184 0.0678 0.0933 0.2500 2.93e-05 2o1s:D
27 2o1s:A 536 184 0.0649 0.0821 0.2391 3.67e-05 2o1s:C
28 2g28:B 801 167 0.0693 0.0587 0.2814 1.10e-04 2g28:A, 2iea:A, 2iea:B, 1l8a:B, 1l8a:A, 3lpl:A, 3lpl:B, 3lq2:A, 3lq2:B, 3lq4:A, 3lq4:B, 2qta:A, 2qta:B, 2qtc:A, 2qtc:B, 1rp7:A, 1rp7:B
29 2g25:B 831 167 0.0693 0.0566 0.2814 1.10e-04 2g25:A
30 8a9c:B 520 105 0.0457 0.0596 0.2952 0.002
31 8bzx:A 546 105 0.0457 0.0568 0.2952 0.002
32 8bzx:B 568 105 0.0457 0.0546 0.2952 0.002
33 6ouv:A 595 167 0.0560 0.0639 0.2275 0.003 2o1x:A, 2o1x:B, 6ouv:B, 8v9i:A, 8v9i:B
34 6ouv:A 595 133 0.0516 0.0588 0.2632 1.1 2o1x:A, 2o1x:B, 6ouv:B, 8v9i:A, 8v9i:B
35 6xxg:AAA 560 167 0.0560 0.0679 0.2275 0.004 6ouw:A
36 6xxg:AAA 560 133 0.0516 0.0625 0.2632 1.3 6ouw:A
37 7a9g:AAA 549 192 0.0752 0.0929 0.2656 0.004 7a9g:BBB, 7a9h:AAA, 7a9h:BBB, 8ogh:A, 8ogh:B
38 6xxg:BBB 539 167 0.0560 0.0705 0.2275 0.004 2o1x:C, 2o1x:D
39 6xxg:BBB 539 202 0.0678 0.0853 0.2277 4.6 2o1x:C, 2o1x:D
40 8a45:F 573 104 0.0413 0.0489 0.2692 0.004 8a29:A, 8a29:B, 8a29:C, 8a29:D, 8a29:E, 8a29:F, 8a45:A, 8a45:B, 8a45:C, 8a45:D, 8a45:E, 8a4d:A, 8a4d:B, 8a4d:C, 8a4d:D, 8a4d:E, 8a4d:F, 8a5k:A, 8a5k:B, 8a5k:C, 8a5k:D, 8a5k:E, 8a5k:F
41 8r2h:B 701 58 0.0265 0.0257 0.3103 0.32 8r2h:A
42 2vpa:A 204 89 0.0354 0.1176 0.2697 2.5 1w3o:A
43 8sk0:B 330 124 0.0457 0.0939 0.2500 2.7 8shh:A, 8shh:B, 8sk0:A
44 3aoe:B 424 64 0.0310 0.0495 0.3281 2.8 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
45 1wyu:A 437 94 0.0324 0.0503 0.2340 4.5 1wyu:C, 1wyu:E, 1wyu:G, 1wyv:A, 1wyv:C, 1wyv:E, 1wyv:G
46 8zc9:B 971 68 0.0295 0.0206 0.2941 4.8 8wyb:A, 8wyb:B, 8wyb:C, 8wyb:D, 8wyc:A, 8wyc:B, 8wyf:A, 8wyf:B, 8zc9:E
47 8zc9:A 1000 68 0.0295 0.0200 0.2941 5.0 8wyc:C, 8wyc:D, 8wyf:C, 8wyf:D, 8ylt:A, 8ylt:B, 8ylt:C, 8ylt:D, 8zc9:D
48 6gua:A 821 113 0.0428 0.0353 0.2566 8.5 6gua:B, 6gua:C, 6gua:D, 6gua:E, 6gua:F, 6gua:G, 6gua:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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