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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEF
CDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKR
ELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

The query sequence (length=213) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8bws:E 215 213 1.0000 0.9907 1.0000 6.26e-162 5c44:E, 5c4a:E, 5c4x:E, 6cnb:E, 2e2i:E, 6eu1:E, 3gtj:E, 3gtk:E, 3gtl:E, 3gtm:E, 6i84:E, 7kef:E, 3m4o:E, 7nky:E, 2nvq:E, 2nvx:E, 5oqm:E, 1r9t:E, 7rim:E, 7rip:E, 7riq:E, 7riw:E, 7rix:E, 7riy:E, 8tug:E, 8tvp:E, 8tvw:E, 8tvx:E, 8tvy:E, 6upx:E, 6upy:E, 6uq0:E, 6uq1:E, 6uq2:E, 6uq3:E, 4y52:E, 4y7n:E, 7z1m:E, 7z1o:E
2 6a5p:E 213 213 0.7371 0.7371 0.7371 3.67e-123 8h0v:E, 8h0w:E, 8he5:E, 6inq:E, 6j4w:E, 6j4x:E, 6j4y:E, 6j4z:E, 6j50:E, 8jh4:E, 7wbv:E, 7wbw:E, 7wbx:E, 7xn7:E, 5xog:E, 7xsx:E, 7xsz:E, 7xt7:E, 7xtd:E, 7xti:E, 8yfq:E
3 7d58:E 210 218 0.4460 0.4524 0.4358 2.31e-59 8a3y:E, 8a40:E, 7ae1:E, 7ae3:E, 7aea:E, 7b0y:E, 8b3d:E, 8b3f:E, 7dn3:E, 6exv:E, 7fji:E, 7fjj:E, 6gmh:E, 6gml:E, 8gxq:PE, 8iue:E, 8iuh:E, 5iy7:E, 5iy8:E, 5iy9:E, 5iyc:E, 5iyd:E, 8oeu:E, 8oev:E, 8oew:E, 8of0:E, 5oik:E, 7okx:E, 7oky:E, 7ol0:E, 7oo3:E, 7oob:E, 7oop:E, 7opc:E, 7opd:E, 8p4a:E, 8p4b:E, 8p4f:E, 7pks:E, 8rbx:E, 8s51:E, 8s52:E, 8s54:E, 8s5n:E, 6ted:E, 8uhd:E, 7und:E, 8w8e:E, 8w8f:E, 8wak:s, 8wal:s, 8wan:s, 8wao:s, 8wap:s, 8waq:s, 8war:s, 8was:s, 8wat:s, 8wau:s, 8wav:s, 8waw:s, 8wax:s, 8way:s, 8waz:s, 8wb0:s
4 8xmc:E 198 209 0.4038 0.4343 0.4115 1.18e-47 8xmd:E, 8xme:E
5 8hyj:E 209 203 0.3099 0.3158 0.3251 4.30e-29
6 2ae8:B 172 53 0.0751 0.0930 0.3019 0.29 2ae8:A, 2ae8:C, 2ae8:D, 2ae8:E, 2ae8:F
7 1lc3:A 292 60 0.0845 0.0616 0.3000 3.1 1lc0:A
8 2h63:D 285 60 0.0845 0.0632 0.3000 4.9 2h63:A, 2h63:B, 2h63:C
9 3u3k:A 289 24 0.0516 0.0381 0.4583 5.7 2a3r:A, 2a3r:B, 2d06:A, 2d06:B, 4gra:A, 4gra:B, 1ls6:A, 3qvu:A, 3qvu:B, 3qvv:A, 3qvv:B, 3u3j:A, 3u3j:B, 3u3k:B, 3u3m:A, 3u3o:A, 3u3r:A, 1z28:A, 1z29:A
10 2gwh:B 288 26 0.0469 0.0347 0.3846 6.5 2gwh:A
11 4tx6:B 310 50 0.0610 0.0419 0.2600 7.5 4tx6:A, 2xtk:A, 2xtk:B, 2xuc:A, 2xuc:B, 2xuc:C, 2xvn:A, 2xvn:B
12 2isq:A 320 70 0.0704 0.0469 0.2143 7.6 1z7w:A, 1z7y:A
13 6q2m:A 544 49 0.0798 0.0312 0.3469 8.9 1ba3:A, 5dwv:A, 4e5d:A, 4g36:A, 4g36:B, 4g37:A, 4g37:B, 5gyz:A, 5gz2:A, 6hps:A, 6hps:B, 3ies:A, 5kyt:A, 5kyt:B, 5kyv:A, 5kyv:B, 6q2m:B, 6q2m:C, 3rix:A, 5wys:A
14 5ju6:A 835 55 0.0704 0.0180 0.2727 10.0 5ju6:B, 5ju6:C, 5ju6:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218