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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
QAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVA
YLEPFIEASKEQGKTNGKMVIATVKGDVGDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADLIGLSGLITPS
LDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETV
RIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVG
VEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFANYCLADFVAPK
LSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENY
QGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYARRKGMS
VTEVERWLAPNLGYDAD

The query sequence (length=577) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3bul:A 577 577 0.9948 0.9948 0.9948 0.0 6bdy:A, 1bmt:A, 1bmt:B, 6bm5:A, 6bm6:A, 3iv9:A, 3iva:A, 1k7y:A, 1k98:A, 1msk:A
2 8sse:A 507 547 0.2964 0.3373 0.3126 1.74e-69 8sse:B, 8sse:C, 8sse:D, 8sse:E, 8sse:F
3 8g3h:A 841 189 0.1421 0.0975 0.4339 1.28e-41
4 2i2x:B 258 182 0.1144 0.2558 0.3626 7.35e-24 2i2x:D, 2i2x:F, 2i2x:H, 2i2x:J, 2i2x:L, 2i2x:N, 2i2x:P
5 7xcn:P 215 202 0.1075 0.2884 0.3069 7.53e-24 7xcn:M, 7xcn:N, 7xcn:O, 7xcn:Q, 7xcn:R
6 4jgi:B 206 137 0.0815 0.2282 0.3431 2.85e-19 4jgi:A
7 3ezx:A 212 167 0.0919 0.2500 0.3174 7.53e-14
8 1y80:A 125 95 0.0537 0.2480 0.3263 3.49e-12
9 8j2x:A 337 90 0.0433 0.0742 0.2778 0.015 8j2w:A, 8j2w:B
10 8j2y:A 327 92 0.0329 0.0581 0.2065 0.057 8j2y:B
11 1id8:A 137 103 0.0399 0.1679 0.2233 0.29
12 7toq:AL12 38 34 0.0225 0.3421 0.3824 0.59 7tor:AL12
13 1cb7:A 137 87 0.0364 0.1533 0.2414 0.71 1cb7:C, 1ccw:A, 1ccw:C, 6h9e:A, 6h9e:C, 6h9f:A, 6h9f:C, 1i9c:A, 1i9c:C
14 3pgy:B 404 92 0.0520 0.0743 0.3261 3.1 3pgy:A
15 8jq5:B 421 127 0.0537 0.0736 0.2441 3.1 8jq3:A, 8jq3:B, 8jq3:C, 8jq3:D, 8jq4:A, 8jq4:B, 8jq4:C, 8jq4:D, 8jq5:A, 8jq5:C, 8jq5:D, 8jq6:A, 8jq6:B, 8jq6:C, 8jq6:D
16 2xn2:A 729 88 0.0416 0.0329 0.2727 3.8
17 3tl1:A 158 63 0.0347 0.1266 0.3175 4.6 3tl1:B
18 8a3w:i 86 36 0.0277 0.1860 0.4444 5.3 8ovj:i
19 3kow:B 728 110 0.0572 0.0453 0.3000 5.7 3kow:A, 3kow:C, 3kow:D, 3kox:A, 3kox:B, 3kox:C, 3kox:D, 3koy:A, 3koy:B, 3koy:D, 3koy:C, 3koz:A, 3koz:B, 3koz:C, 3koz:D, 3kp0:A, 3kp0:B, 3kp0:C, 3kp0:D, 3kp1:C, 3kp1:A, 3kp1:D, 3kp1:B
20 1h7a:A 563 79 0.0364 0.0373 0.2658 6.8 1h78:A, 1h79:A, 1h7b:A, 1hk8:A
21 1hlm:A 158 32 0.0243 0.0886 0.4375 7.8
22 5a01:A 681 46 0.0260 0.0220 0.3261 8.4 5a01:B, 5a01:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218