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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PYPFKLPDLGYPYEALEPHIDAKTMEIHHQKHHGAYVTNLNAALEKYPYLHGVEVEVLLRHLAALPQDIQTAVRNNGGGH
LNHSLFWRLLTPGGAKEPVGELKKAIDEQFGGFQALKEKLTQAAMGRFGSGWAWLVKDPFGKLHVLSTPNQDNPVMEGFT
PIVGIDVWEHAYYLKYQNRRADYLQAIWNVLNWDVAEEFFKKA

The query sequence (length=203) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3mds:A 203 203 1.0000 1.0000 1.0000 7.29e-152 3mds:B, 1mng:A, 1mng:B
2 6pro:A 202 201 0.6256 0.6287 0.6318 2.91e-94 6pro:B
3 1gv3:A 213 191 0.5517 0.5258 0.5864 3.64e-86 1gv3:B
4 1xuq:A 200 199 0.5665 0.5750 0.5779 1.04e-84 1xuq:B
5 2rcv:A 200 199 0.5714 0.5800 0.5829 9.53e-83 2rcv:B, 2rcv:C, 2rcv:D, 2rcv:E, 2rcv:F, 2rcv:G, 2rcv:H
6 6bej:E 201 200 0.5665 0.5721 0.5750 1.77e-81 6bej:A
7 1jr9:A 201 201 0.5567 0.5622 0.5622 3.64e-81
8 7wnk:D 202 200 0.5714 0.5743 0.5800 4.29e-81 7ddw:A, 7ddw:B, 7ddw:C, 7ddw:D, 7ddw:E, 7ddw:F, 6m30:A, 6m30:B, 6m30:C, 6m30:D, 6m30:E, 6m30:F, 7w6w:A, 7w6w:B, 7w6w:D, 7wnk:A, 7wnk:B, 7wnk:C, 7wnl:A, 7wnl:B, 7wnl:C, 7wnl:D, 5x2j:A
9 4yio:A 202 198 0.5369 0.5396 0.5505 1.87e-78 4yio:B
10 1xre:A 201 200 0.5419 0.5473 0.5500 1.88e-77 1xre:B
11 5n56:A 198 197 0.5369 0.5505 0.5533 2.10e-77 6ex3:A, 6ex3:B, 6ex3:C, 6ex3:D, 5n56:B, 6qv9:A, 6qv9:B, 7w6w:C
12 4jyy:A 202 198 0.5222 0.5248 0.5354 6.30e-75 4jz2:A, 4jzg:A, 3tjt:A
13 1y67:D 214 211 0.5764 0.5467 0.5545 2.02e-74 2aw9:A, 2aw9:B, 2cdy:A, 2cdy:B, 2cdy:C, 2cdy:D, 2ce4:A, 2ce4:B, 3kky:A, 3kky:B, 1y67:A, 1y67:B, 1y67:C
14 5a9g:A 206 204 0.5616 0.5534 0.5588 2.81e-74 5a9g:B, 6gsb:A, 6gsb:B, 6gsc:A, 6gsc:B
15 4yip:A 203 198 0.5271 0.5271 0.5404 4.78e-72 4yip:B, 4yip:C, 4yip:D
16 8avk:A 202 196 0.5074 0.5099 0.5255 5.00e-72 8avk:B, 8avn:A, 8avn:B
17 8kb3:A 206 204 0.5369 0.5291 0.5343 1.51e-69 1d5n:A, 1d5n:B, 1d5n:C, 1d5n:D, 1en4:A, 1en4:B, 1en4:C, 1en4:D, 1en5:A, 1en5:B, 1en5:C, 1en5:D, 1en6:A, 1en6:B, 1en6:C, 1en6:D, 1i08:A, 1i08:B, 1i08:C, 1i08:D, 1i0h:A, 1i0h:B, 1ix9:A, 1ix9:B, 3k9s:A, 3k9s:B, 3k9s:C, 3k9s:D, 8kb3:B, 1mmm:A, 1mmm:B, 1vew:A, 1vew:B, 1vew:C, 1vew:D, 1zlz:B
18 6ex4:A 198 200 0.4926 0.5051 0.5000 1.50e-68 6ex4:B, 6ex5:A, 6ex5:B, 5n57:A, 5n57:B, 6qv8:A, 6qv8:B
19 7kks:A 199 199 0.5025 0.5126 0.5126 9.48e-64 2adp:A, 2adq:B, 1ap5:A, 1ap5:B, 1ap6:A, 1ap6:B, 3c3s:A, 3c3s:B, 3c3t:A, 3c3t:B, 1em1:A, 1em1:B, 2gds:A, 2gds:B, 2gds:C, 2gds:D, 5gxo:A, 5gxo:B, 1ja8:A, 1ja8:B, 7kks:B, 7kku:A, 7kku:B, 7kkw:A, 7kkw:B, 7klb:A, 7klb:B, 1luv:A, 1luv:B, 1luw:A, 1luw:B, 1msd:A, 1msd:B, 1n0j:A, 1n0j:B, 1n0n:A, 1n0n:B, 2p4k:A, 2p4k:B, 2p4k:C, 2p4k:D, 1pl4:A, 1pl4:B, 1pl4:C, 1pl4:D, 1pm9:A, 1pm9:B, 2qka:A, 2qka:C, 2qkc:A, 2qkc:C, 1qnm:A, 1qnm:B, 8sks:A, 8sks:B, 8sks:C, 8sks:D, 1szx:A, 1szx:B, 5t30:A, 5t30:B, 1var:A, 1var:B, 5vf9:A, 5vf9:B, 8vhw:A, 8vhw:B, 8vhy:A, 8vhy:B, 8vj0:A, 8vj0:B, 8vj4:A, 8vj4:B, 8vj5:A, 8vj5:B, 8vj8:A, 8vj8:B, 1xdc:A, 1xdc:B, 1xil:A, 1xil:B, 1zsp:A, 1zsp:B, 1zte:A, 1zte:B, 1zte:C, 1zte:D, 1zuq:A, 1zuq:B
20 4c7u:A 203 205 0.4778 0.4778 0.4732 5.33e-58 4c7u:B, 4c7u:C, 4c7u:D, 4c7u:E, 4c7u:F, 4c7u:G, 4c7u:H
21 3tqj:A 192 198 0.4384 0.4635 0.4495 9.24e-58 3tqj:B
22 4br6:B 197 202 0.4778 0.4924 0.4802 6.85e-56 4br6:A, 4br6:C, 4br6:D
23 1kkc:A 200 203 0.4532 0.4600 0.4532 8.64e-54 1kkc:B, 1kkc:X, 1kkc:Y
24 6jov:C 198 197 0.4286 0.4394 0.4416 1.43e-53 6jov:A, 6jov:B, 6jov:D
25 6cyp:A 211 206 0.4729 0.4550 0.4660 2.50e-53 6cyl:A, 6cyl:B, 6cyl:C, 6cyl:D, 6cyp:B, 6cyp:C, 6cyp:D, 6cyp:E, 6cyp:F, 6cys:A, 6cys:B, 6cys:C, 6cys:D, 6cyx:A, 6cyx:B, 6cyx:C, 6cyx:D, 6cyx:E, 6cyx:F, 6dqy:A, 6dqy:B, 6dqy:C, 6dqy:D, 6dqy:E, 6dqy:F, 6dqy:G, 6dqy:H, 6dqy:I, 6dqy:J, 6dqy:K, 6dqy:L, 6dqy:M, 6dqy:N, 6dqy:O, 6dqy:P, 6dqy:Q, 6dqy:R, 6dqy:S, 6dqy:T, 6dqy:U, 6dqy:V, 6dqy:W, 6dqy:X, 7svs:A, 7svs:B, 7svs:C, 7svs:D, 7svs:E, 7svs:F, 7svs:G, 7svs:H, 5tir:A, 5tir:B, 5tir:C, 5tir:D
26 8avl:A 192 196 0.4335 0.4583 0.4490 3.00e-53 8avl:B, 8avl:C, 8avl:D, 8avl:E, 8avl:F, 8avl:G, 8avl:H, 8avm:A, 8avm:B, 8avm:C, 8avm:D, 8avm:E, 8avm:F
27 1qnn:A 191 194 0.4089 0.4346 0.4278 4.55e-53 1qnn:B, 1qnn:C, 1qnn:D, 1uer:A, 1uer:B, 1uer:C, 1uer:D, 1ues:A, 1ues:B, 1ues:C, 1ues:D
28 1dt0:A 197 197 0.4089 0.4213 0.4213 8.38e-52 1dt0:B, 1dt0:C, 3sdp:A, 3sdp:B
29 2bkb:A 192 191 0.4039 0.4271 0.4293 1.24e-51 2bkb:B, 2bkb:C, 2bkb:D, 1isa:A, 1isa:B, 1isb:A, 1isb:B, 1isc:A, 1isc:B, 2nyb:A, 2nyb:B, 2nyb:C, 2nyb:D, 1za5:A, 1za5:B
30 3dc6:C 198 201 0.4433 0.4545 0.4478 3.92e-51 3dc6:A
31 3h1s:B 192 197 0.3990 0.4219 0.4112 1.36e-50 3h1s:A
32 2cw2:A 199 201 0.3892 0.3970 0.3930 1.85e-50 2cw2:B
33 4l2a:A 192 198 0.3941 0.4167 0.4040 5.64e-50 4l2a:B, 4l2b:A, 4l2b:B, 4l2c:A, 4l2c:B, 4l2c:D, 4l2c:C, 4l2d:A, 4l2d:D, 4l2d:C, 4l2d:B, 3lio:A, 3lio:B, 3lj9:B, 3lj9:A, 3ljf:A, 3ljf:C, 3ljf:B, 3ljf:D
34 4e4e:B 207 200 0.4335 0.4251 0.4400 4.76e-49 3bfr:A, 4e4e:A, 4e4e:C, 4e4e:D, 4f6e:A, 4f6e:B, 4f6e:C, 4f6e:D, 3lsu:A, 3lsu:B, 3lsu:C, 3lsu:D, 3rn4:A
35 2bpi:A 197 199 0.3793 0.3909 0.3869 7.72e-49 2bpi:B
36 1ar4:A 201 203 0.4236 0.4279 0.4236 1.19e-48 1ar4:B, 1ar5:A, 1ar5:B, 1avm:A, 1avm:B, 1bs3:A, 1bs3:B, 1bsm:A, 1bsm:B, 1bt8:A, 1bt8:B
37 5ag2:C 195 198 0.4286 0.4462 0.4394 1.93e-48 5ag2:A, 3dc5:A, 3dc5:C, 6elk:A, 6elk:C, 6qzm:A, 6qzm:C, 6qzn:A, 6qzn:C, 6s0d:A, 6s0d:C, 4x9q:A, 4x9q:C
38 2a03:A 197 199 0.3793 0.3909 0.3869 5.52e-48 2a03:B, 2goj:A, 2goj:B
39 2w7w:A 193 200 0.3941 0.4145 0.4000 9.09e-48 2w7w:B
40 8bhx:A 203 199 0.4138 0.4138 0.4221 1.85e-47 8bhx:B
41 3esf:A 197 202 0.4089 0.4213 0.4109 8.51e-47 3esf:B, 3esf:C, 3esf:D
42 4f2n:B 210 204 0.3892 0.3762 0.3873 1.90e-46 4f2n:A, 4f2n:C, 4f2n:D, 4f2n:E, 4f2n:F, 4f2n:G, 4f2n:H, 4f2n:I, 4f2n:J, 4f2n:K, 4f2n:L
43 4gun:A 205 205 0.4236 0.4195 0.4195 4.68e-45 4gun:B, 4gun:C, 4gun:D, 4gun:E, 4gun:F, 4gun:G, 4gun:H, 4gun:I, 4gun:J, 4gun:K, 4gun:L, 4gun:M, 4gun:N, 4gun:O, 4gun:P, 3qvn:A
44 4yet:B 200 196 0.3596 0.3650 0.3724 3.74e-44 4yet:A
45 2gpc:A 194 198 0.3744 0.3918 0.3838 2.26e-43 2gpc:B
46 8r5o:I 215 195 0.3744 0.3535 0.3897 3.73e-43 8qma:G, 8r6s:I, 8ras:I, 8rdj:I
47 7azq:A 199 193 0.3744 0.3819 0.3938 5.63e-43 7azq:E, 7azr:A, 7azr:E
48 4h3e:A 214 204 0.3695 0.3505 0.3676 9.51e-43 4dvh:A, 4dvh:B, 4h3e:B
49 1my6:A 198 182 0.3793 0.3889 0.4231 1.84e-42 1my6:B
50 7sbh:A 208 196 0.3744 0.3654 0.3878 2.82e-42
51 1ma1:A 201 204 0.3744 0.3781 0.3725 5.55e-42 1ma1:B, 1ma1:C, 1ma1:D, 1ma1:E, 1ma1:F
52 1gn2:A 198 198 0.3744 0.3838 0.3838 3.14e-41 1gn2:B, 1gn2:C, 1gn2:D, 1gn2:E, 1gn2:F, 1gn2:G, 1gn2:H, 1gn3:A, 1gn3:B, 1gn4:A, 1gn4:B, 1gn4:C, 1gn4:D, 1gn6:A, 1gn6:B, 1gn6:C, 1gn6:D, 1ids:A, 1ids:B, 1ids:C, 1ids:D
53 6j55:L 203 199 0.3892 0.3892 0.3970 8.05e-41 6j55:A, 6j55:B, 6j55:C, 6j55:D, 6j55:E, 6j55:F, 6j55:G, 6j55:H, 6j55:I, 6j55:J, 6j55:K
54 3ak3:B 213 207 0.3990 0.3803 0.3913 5.99e-40 3ak2:A, 3ak2:B, 3ak2:C, 3ak2:D, 3ak3:A, 3ak3:C, 3ak3:D
55 8w9z:G 218 198 0.3695 0.3440 0.3788 1.56e-39 8wa0:G, 8wa1:G
56 8wa0:L 235 198 0.3793 0.3277 0.3889 3.91e-39 8w9z:L, 8wa1:L
57 4ffk:A 212 204 0.3892 0.3726 0.3873 2.01e-38
58 8r6s:N 224 217 0.3596 0.3259 0.3364 3.37e-38 7bjk:A, 7bjk:B, 7bjk:C, 7bjk:D, 7bjk:E, 8qma:L, 8r5o:N, 8ras:N, 8rdj:N
59 3evk:A 211 203 0.3941 0.3791 0.3941 2.33e-37 3evk:B, 3evk:C, 3evk:D
60 3js4:A 207 201 0.3695 0.3623 0.3731 2.85e-35 3js4:B, 3js4:C, 3js4:D
61 1unf:X 214 209 0.3990 0.3785 0.3876 6.11e-34
62 1wb7:A 205 205 0.3498 0.3463 0.3463 2.58e-32 1wb7:B, 1wb8:A, 1wb8:B
63 2cw3:A 200 197 0.3547 0.3600 0.3655 6.10e-31 2cw3:B
64 1b06:A 208 208 0.3498 0.3413 0.3413 3.46e-30 1b06:B, 1b06:C, 1b06:D, 1b06:E, 1b06:F
65 3cei:A 213 201 0.3054 0.2911 0.3085 1.03e-29 3cei:B
66 1coj:A 211 197 0.3251 0.3128 0.3350 9.95e-26
67 7pub:Cr 267 73 0.1232 0.0936 0.3425 1.79e-05 6hiv:Cr, 6hiw:Cr, 6hiy:Cr
68 8om2:3 257 145 0.1576 0.1245 0.2207 0.002 8d8k:3, 8d8l:3, 5mrc:33, 5mre:33, 5mrf:33, 8om3:3, 8om4:3
69 6yw5:44 260 151 0.1626 0.1269 0.2185 0.014 6ywe:44, 6ywx:44, 6ywy:44
70 7aor:y 253 122 0.1675 0.1344 0.2787 0.014
71 6nr7:A 1086 68 0.0837 0.0157 0.2500 7.4 4dj9:A, 4e17:A, 6fq4:A, 2gdc:A, 2gww:A, 2hsq:A, 2ibf:A, 5l0c:B, 5l0c:C, 5l0c:D, 5l0d:B, 5l0d:D, 5l0g:B, 5l0g:C, 5l0h:A, 4pr9:D, 4pr9:E, 4pr9:F, 3rf3:A, 3rf3:B, 1rkc:A, 3s90:A, 3s90:B, 1syq:A, 1t01:A, 3tj5:A, 3tj6:A, 1u6h:A, 1xwj:A, 1ydi:A, 3zdl:A, 1zvz:A, 1zw2:A, 1zw3:A
72 3ke5:A 182 19 0.0591 0.0659 0.6316 7.6 3ke5:C, 3ke5:B
73 4chu:B 127 53 0.0887 0.1417 0.3396 7.6
74 8ddw:A 695 82 0.1281 0.0374 0.3171 8.6 8ddw:B, 8ddw:C
75 6c66:G 832 31 0.0640 0.0156 0.4194 9.4

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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