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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PWELTILHTNDVHSRLEQTSEDSSKCVDASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFM
NALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLS
NPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPF
IVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLDSSIPEDPSIKADINKWRIKLDDYSTQELGKTIVY
LDGSSQSCRFRECNMGNLICDAMINNNLRHADEMFWNHVSMCILNGGGIRSPIDERNDGTITWENLAAVLPFGGTFDLVQ
LKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTACAVPSYDPLKMDEVYKVILPNFLANGG
DGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFS

The query sequence (length=524) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7jv8:C 529 523 0.9905 0.9811 0.9924 0.0 7bbj:A, 7bbj:B, 4h1s:A, 4h1s:B, 4h1y:P, 4h2b:A, 4h2f:A, 4h2g:A, 4h2i:A, 6hxw:A, 6hxw:B, 7jv8:A, 7jv8:B, 7jv8:D, 7jv9:A, 7jv9:B, 7p9n:A, 7p9r:A, 7p9t:A, 7pa4:A, 7pb5:A, 7pba:A, 7pbb:A, 7pby:A, 7pcp:A, 7pd9:A, 7qga:A, 7qgl:A, 7qgm:A, 7qgo:A, 6s7f:A, 6s7h:A, 6tve:P, 6tvg:A, 6tvx:A, 6tw0:A, 6twa:A, 6twf:A, 6vc9:A, 6xue:A, 6xue:B, 6xug:A, 6xug:B, 6xuq:A, 6ye1:A, 6ye1:B, 6ye2:A, 6ye2:B, 6z9b:A, 6z9d:A
2 5h7w:B 529 524 0.6870 0.6805 0.6870 0.0 7d0v:A, 7d0v:B, 5h7w:A
3 2z1a:A 507 524 0.3874 0.4004 0.3874 4.00e-103
4 3ztv:A 565 529 0.3015 0.2796 0.2987 1.20e-48 3zu0:A
5 3zu0:B 505 506 0.2805 0.2911 0.2905 2.70e-45
6 3ivd:A 499 516 0.2595 0.2725 0.2636 4.22e-33 3ivd:B, 3ive:A
7 1ho5:A 525 545 0.2557 0.2552 0.2459 9.15e-28 1ho5:B, 1hp1:A, 1hpu:A, 1hpu:B, 1hpu:C, 1hpu:D, 1oi8:A, 1oi8:B, 1ush:A, 2ush:A, 2ush:B, 4wwl:A
8 3gve:A 334 321 0.1775 0.2784 0.2897 2.26e-23 3gve:B
9 4q7f:A 510 479 0.2042 0.2098 0.2234 3.65e-15 3qfk:A
10 5eqv:A 336 292 0.1450 0.2262 0.2603 3.10e-10
11 3jyf:A 336 252 0.1202 0.1875 0.2500 4.70e-10 3jyf:B
12 4uwq:A 548 206 0.1031 0.0985 0.2621 5.39e-09 4uwq:D, 4uwq:G, 4uwq:J, 2wdc:A, 2wdd:A, 2wde:A, 2wdf:A
13 5cot:A 340 85 0.0515 0.0794 0.3176 1.6 5cou:A, 6vt1:A, 6vt1:B, 6vt1:C, 6vt1:D, 6vt6:A, 6vt8:A, 6vt9:A, 6vtb:A, 6vtd:A, 6vte:A, 6vtf:A, 6vtf:B, 6vtf:C, 6vtf:D
14 6g90:T 462 81 0.0324 0.0368 0.2099 3.7 7dco:u, 4dgw:A, 5nrl:T, 5zwm:u
15 6clx:B 342 103 0.0534 0.0819 0.2718 4.0 6clx:A
16 6tj7:A 134 20 0.0210 0.0821 0.5500 5.1
17 7eap:A 755 67 0.0382 0.0265 0.2985 6.2 5yot:A, 5yot:B, 5yqs:A, 5yqs:B
18 8aaf:a 848 45 0.0210 0.0130 0.2444 7.0 8agt:a, 8agu:a, 8agv:a, 8agw:a, 8agx:a, 8agz:a

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218