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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PVVVDIHTHMYPPSYIAMLEKRQTIPLVRTFPQADEPRLILLSSELAALDAALADPAAKLPGRPLSTHFASLAQKMHFMD
TNGIRVSVISLANPWFDFLAPDEAPGIADAVNAEFSDMCAQHVGRLFFFAALPLSAPVDAVKASIERVKNLKYCRGIILG
TSGLGKGLDDPHLLPVFEAVADAKLLVFLHPHYGLPNEVYGPRSEEYGHVLPLALGFPMETTIAVARMYMAGVFDHVRNL
QMLLAHSGGTLPFLAGRIESCIVHDGHLVKTGKVPKDRRTIWTVLKEQIYLDAVIYSEVGLQAAIASSGADRLMFGTAHP
FFPPIEEDVQGPWDSSRLNAQAVIKAVGEGSSDAAAVMGLNAVRVLSL

The query sequence (length=368) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4hk5:D 380 368 0.9973 0.9658 0.9973 0.0 4hk5:A, 4hk5:B, 4hk5:C, 4hk6:A, 4hk6:B, 4hk6:C, 4hk6:D, 4hk7:A, 4hk7:B, 4hk7:C, 4hk7:D, 4lak:A, 4lak:B, 4lal:A, 4lal:B, 4lal:C, 4lal:D, 4lam:A, 4lam:B, 4lao:A, 4lao:B
2 4hjw:C 378 368 0.7255 0.7063 0.7255 0.0 4hjw:A, 4hjw:B
3 4ofc:A 335 248 0.1875 0.2060 0.2782 1.16e-21 4igm:A, 4igm:B, 4igm:C, 4igm:D, 4igm:E, 4igm:F, 4ign:A, 4ign:B, 4ign:C, 4ign:D, 4ign:E, 4ign:F, 4ih3:A, 4ih3:B, 4ih3:C, 4ih3:D, 4ih3:E, 4ih3:F, 4ofc:B, 4ofc:C, 4ofc:D, 4ofc:E, 4ofc:F, 7pwy:A, 7pwy:B, 7pwy:D, 2wm1:A
4 7pwy:C 301 248 0.1821 0.2226 0.2702 3.30e-21
5 2dvt:A 325 344 0.2690 0.3046 0.2878 6.30e-19 2dvt:B, 2dvt:C, 2dvt:D, 2dvu:A, 2dvu:B, 2dvu:C, 2dvu:D, 2dvx:A, 2dvx:B, 2dvx:C, 2dvx:D
6 4icm:A 335 271 0.1848 0.2030 0.2509 1.79e-17 4icm:B, 4icm:C, 4icm:D, 4icm:E, 4icm:F, 4icm:G, 4icm:H, 4l6d:A, 4l6d:B, 4l6d:C, 4l6d:D, 4l6d:E, 4l6d:F, 4l6d:G, 4l6d:H, 4ng3:A, 4ng3:B, 4ng3:C, 4ng3:D, 4ng3:E, 4ng3:F, 4ng3:G, 4ng3:H, 4ni8:A, 4ni8:B, 4ni8:C, 4ni8:D, 4ni8:E, 4ni8:F, 4ni8:G, 4ni8:H
7 4qro:A 332 291 0.2147 0.2380 0.2715 1.31e-16 4qro:B, 4qro:C, 4qro:D, 4qro:E, 4qro:F, 4qro:G, 4qro:H
8 4era:A 332 362 0.2147 0.2380 0.2182 3.36e-15 4epk:A, 4epk:B, 4era:B, 4erg:A, 4erg:B, 4eri:A, 4eri:B, 2hbv:A, 2hbv:B, 2hbx:A, 2hbx:B, 4ifk:A, 4ifk:B, 4ifo:A, 4ifo:B, 4ifr:A, 4ifr:B, 4ig2:A, 4ig2:B, 7k12:A, 7k13:A, 7k13:B, 7k13:C, 6mgs:A, 6mgs:B, 6mgs:C, 6mgt:A, 6mgt:B
9 3ij6:A 303 239 0.1793 0.2178 0.2762 5.48e-14 3ij6:B, 3ij6:C, 3ij6:D
10 6m53:B 339 262 0.1821 0.1976 0.2557 7.90e-13 7bp1:A, 7bp1:C, 7bp1:D, 7bpc:A, 7bpc:C, 6m53:A, 6m53:C, 6m53:D
11 4qrn:A 352 250 0.1685 0.1761 0.2480 8.92e-13 4inf:A, 4inf:B, 4inf:C, 4inf:D, 4qrn:B, 4qrn:C, 4qrn:D, 4qs5:A, 4qs5:B, 4qs5:C, 4qs5:D, 4qs6:A, 4qs6:B, 4qtg:A, 4qtg:B
12 5vn5:C 334 199 0.1440 0.1587 0.2663 1.31e-12 6e6i:A, 6e6i:B, 6e6i:C, 6e6i:D, 6e6i:E, 6e6i:F, 6e6i:G, 6e6i:H, 6e6i:I, 5vn5:A, 5vn5:B
13 3nur:A 305 258 0.1386 0.1672 0.1977 2.51e-11
14 7a19:A 339 340 0.1984 0.2153 0.2147 3.04e-09 7a19:B, 7a1a:A, 7a1a:B, 7wjr:A, 7wjr:B, 7wjr:C, 7wjr:D, 7wkl:A, 7wkl:B, 7wkl:C, 7wkl:D, 7wkm:A, 7wkm:B, 7wmb:A, 7wmb:B
15 8h41:B 357 313 0.1984 0.2045 0.2332 8.68e-09 8h41:A, 6jqw:A, 6jqw:B, 6jqx:A, 6jqx:B
16 2f6k:A 306 183 0.1304 0.1569 0.2623 1.09e-08 2f6k:B
17 6dxs:A 342 96 0.0571 0.0614 0.2188 0.13 6dwv:B, 6dwv:A, 6dwv:C, 6dwv:D, 6dxq:A, 6dxq:B, 6dxq:C, 6dxq:D, 6dxs:B, 6dxs:C, 6dxs:D
18 8sm9:F 344 207 0.1332 0.1424 0.2367 0.36 8sm9:B, 8sm9:D, 8sm9:H
19 8e72:B 598 107 0.0870 0.0535 0.2991 1.3 8dhw:A, 8dhw:B, 8e72:A
20 8htu:F 161 75 0.0679 0.1553 0.3333 1.5 7ksq:F, 7kux:F, 6l35:F, 7xqp:F
21 8cmo:F 165 42 0.0489 0.1091 0.4286 2.4
22 8sm7:A 347 173 0.1196 0.1268 0.2543 3.2 8sm7:B, 8sm7:D, 8sm7:G
23 1php:A 394 114 0.0788 0.0736 0.2544 3.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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