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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PVTLAKVIKVLGRTGSRGGVTQVRVEFLEDTTRTIVRNVKGPVREGDILVLMESEREARRLR

The query sequence (length=62) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6fyx:c 64 62 1.0000 0.9688 1.0000 1.88e-37 7a1g:h, 7ajt:Dc, 7aju:Dc, 7b7d:L, 8bn3:D8, 8bqd:L, 8bqx:L, 8c00:L, 8c01:L, 8c3a:e, 8c3a:DP, 8cah:h, 8cas:i, 8cbj:c, 8ccs:4, 8cdl:4, 8cdr:4, 8ceh:4, 8cf5:4, 8cg8:4, 8cgn:4, 8civ:4, 8cku:4, 8cmj:4, 8cq7:e, 8cq7:DP, 8cqw:e, 8cqw:DP, 8cre:e, 8cre:DP, 7d4i:Sd, 7d5s:Sd, 7d5t:Sd, 7d63:Sd, 5dat:D8, 5dat:d8, 5dc3:D8, 5dc3:d8, 5dge:D8, 5dge:d8, 5dgf:D8, 5dgf:d8, 5dgv:D8, 5dgv:d8, 6eml:L, 8eub:Bc, 8evp:Bc, 8evq:Bc, 8evr:Bc, 8evs:Bc, 8evt:Bc, 8ewb:Bc, 8ewc:Bc, 6fai:c, 5fci:D8, 5fci:d8, 5fcj:D8, 5fcj:d8, 6fyy:c, 6gq1:AS, 6gqb:AS, 6gqv:AS, 6gsm:c, 6gsn:c, 6hhq:d, 6hhq:d8, 5i4l:D8, 5i4l:d8, 6i7o:L, 6i7o:Lb, 8i7j:c, 5it7:c, 5it9:c, 3j6x:28, 3j6y:28, 3j77:28, 3j78:28, 3j80:c, 3j81:c, 3jam:c, 3jap:c, 5jpq:1, 5juo:ZB, 5jup:ZB, 5jus:ZB, 5jut:ZB, 5juu:ZB, 8k2d:Sc, 8k82:Sc, 6ke6:Sd, 6lqp:Sd, 6lqq:Sd, 6lqr:Sd, 6lqs:Sd, 6lqt:Sd, 6lqu:Sd, 6lqv:Sd, 5lyb:D8, 5lyb:d8, 5m1j:c2, 5mc6:L, 5mei:d8, 5mei:d, 7mpi:Bc, 7mpj:Bc, 7n8b:Bc, 5ndg:D8, 5ndg:d8, 5ndv:D8, 5ndv:d8, 5ndw:D8, 5ndw:d8, 7nrc:SL, 7nrd:SL, 5obm:D8, 5obm:d8, 8oeq:e, 8oeq:DP, 5on6:d8, 5on6:d, 7osa:eS28, 7osm:eS28, 7pzy:d, 7q08:d, 7q0f:d, 7q0p:d, 7q0r:d, 8q5i:d, 6q8y:L, 6rbd:c, 6rbe:c, 7rr5:Sc, 8rw1:c, 6s47:Bd, 8s8d:c, 8s8e:c, 8s8f:c, 8s8g:c, 8s8h:c, 8s8i:c, 8s8j:c, 6snt:c, 7suk:LG, 6sv4:L, 6sv4:Lb, 6sv4:Lc, 6t4q:Sc, 6t7i:Sc, 6t7t:Sc, 6t83:cb, 6t83:3, 5tbw:d, 5tbw:d8, 6tb3:L, 5tga:D8, 5tga:d8, 5tgm:D8, 5tgm:d8, 6tnu:L, 5tzs:G, 4u3m:D8, 4u3m:d8, 4u3n:D8, 4u3n:d8, 4u3u:D8, 4u3u:d8, 4u4n:D8, 4u4n:d8, 4u4o:D8, 4u4o:d8, 4u4q:D8, 4u4q:d8, 4u4r:D8, 4u4r:d8, 4u4u:D8, 4u4u:d8, 4u4y:D8, 4u4y:d8, 4u4z:D8, 4u4z:d8, 4u50:D8, 4u50:d8, 4u51:D8, 4u51:d8, 4u52:D8, 4u52:d8, 4u53:D8, 4u53:d8, 4u55:D8, 4u55:d8, 4u56:D8, 4u56:d8, 4u6f:D8, 4u6f:d8, 4uer:1, 6uz7:c, 4v7r:AR, 4v7r:CR, 4v88:Ac, 4v88:Cc, 4v8y:A2, 4v8z:A2, 4v92:Bc, 6wdr:c, 5wlc:LG, 6woo:cc, 5wyj:Sd, 5wyk:Sd, 6xiq:AS, 6xir:AS, 8y0u:Sc, 6y7c:c, 6z6j:Sc, 6z6k:Sc, 6zce:d, 7zpq:Ac, 6zqa:Dc, 6zqb:Dc, 6zqc:Dc, 6zqd:Dc, 6zqe:Dc, 6zqg:Dc, 7zrs:Ac, 6zu9:i, 7zuw:Ac, 7zux:Dc, 6zvi:N, 7zw0:sL
2 7r81:d2 62 61 0.8065 0.8065 0.8197 2.75e-30 7olc:Sc, 7old:Sc, 8oo0:Sc, 5oql:z, 6rxt:Cp, 6rxu:Cp, 6rxv:Cp, 6rxx:Cp, 6rxy:Cp, 6rxz:Cp, 7z3n:Sc, 7z3o:Sc
3 7syg:d 67 62 0.7581 0.7015 0.7581 4.04e-30 7a01:f3, 7a09:S, 5a2q:c, 5aj0:Bc, 9bdl:AS28, 9bdn:AS28, 9bdp:AS28, 8bhf:d3, 9bkd:n, 9bln:n, 8btk:AB, 7cpu:Sc, 7cpv:Sc, 4d5l:c, 4d61:c, 6d90:dd, 6d9j:dd, 9f1b:AB, 9f1c:AB, 9f1d:AB, 6fec:l, 5flx:c, 6g18:c, 6g4s:c, 6g4w:c, 6g51:c, 6g53:c, 6g5h:c, 6g5i:c, 8g5y:Sc, 8g5z:Sc, 8g60:Sc, 8g61:Sc, 8g6j:Sc, 8glp:Sc, 6gz3:Bc, 6gz4:Bc, 6gz5:Bc, 6hcf:d1, 6hcj:d2, 6hcm:d1, 6hcq:d2, 8ifd:3D, 8ife:3D, 6ip5:3D, 6ip6:3D, 6ip8:3D, 3j7p:Sc, 3j7r:Sc, 3jag:cc, 3jah:cc, 3jai:cc, 3jaj:Sc, 3jan:Sc, 8jdj:AO, 8jdk:AO, 8jdl:AO, 8jdm:AO, 7jqb:d, 7jqc:d, 5k0y:l, 8k2c:Sc, 7k5i:c, 4kzx:c, 4kzy:c, 4kzz:c, 5lks:Sc, 7ls1:G3, 7ls2:G3, 5lzs:cc, 5lzt:cc, 5lzu:cc, 5lzv:cc, 5lzw:cc, 5lzx:cc, 5lzy:cc, 5lzz:cc, 7mdz:cc, 7mq8:LG, 7mq9:LG, 7mqa:LG, 6mtb:cc, 6mtc:cc, 6mtd:cc, 6mte:cc, 7nwg:d2, 7nwh:cc, 7nwi:cc, 7o7y:AB, 7o7z:AB, 7o80:AB, 7o81:AB, 5oa3:c, 6ole:Sc, 6olf:Sc, 6olg:Bc, 6oli:Sc, 6olz:Bc, 6om0:Sc, 6om7:Sc, 7oya:c2, 7oyb:c2, 7oyc:c2, 8oz0:s, 8p03:d, 8p09:d, 8p2k:AB, 6p4g:d, 6p4h:d, 6p5i:d, 6p5j:d, 6p5k:d, 6p5n:d, 8pj1:n, 8pj2:n, 8pj3:n, 8pj4:n, 8pj5:n, 8pj6:n, 8ppk:c, 8ppl:Ac, 8q7z:AB, 8q87:AB, 7qgg:Sc, 8qoi:Sc, 7qp6:n, 7qp7:n, 7qvp:Sc, 7qvp:Rc, 6qzp:Sc, 7r4x:c, 6r5q:FF, 6r6g:FF, 6r6p:FF, 6r7q:FF, 8rg0:n, 8scb:cc, 6sgc:d1, 7syh:d, 7syi:d, 7syj:d, 7syk:d, 7syl:d, 7sym:d, 7syn:d, 7syo:d, 7syp:d, 7syq:d, 7syr:d, 7sys:d, 7syt:d, 7syu:d, 7syv:d, 7syw:d, 7syx:d, 5t2c:AF, 8t4s:c, 7toq:AS28, 7tor:AS28, 7tql:d, 7ucj:Cc, 7uck:Cc, 4ug0:Sc, 4ujc:Cc, 4ujd:Cc, 4uje:Bc, 4v6x:Ac, 5vyc:c1, 5vyc:c2, 5vyc:c3, 5vyc:c4, 5vyc:c5, 5vyc:c6, 6w2s:d, 6w2t:d, 7wtt:c, 7wtu:c, 7wtv:c, 7wtw:c, 7wtx:c, 7wtz:c, 7wu0:c, 6xa1:Sc, 7xnx:Sc, 7xny:Sc, 8xsx:Sc, 8xsy:Sc, 8xsz:Sc, 8xxl:Sc, 8xxm:Sc, 8xxn:Sc, 6y0g:Sc, 8y0w:Sc, 8y0x:Sc, 6y2l:Sc, 6y57:Sc, 6yal:d, 6yam:d, 6yan:d, 6ybs:n, 8yoo:Sc, 8yop:Sc, 6z6l:Sc, 6z6m:Sc, 6z6n:Sc, 7zjw:SC, 7zjx:SC, 6zlw:d, 6zm7:Sc, 6zme:Sc, 6zmi:Sc, 6zmo:Sc, 6zmt:d, 6zmw:n, 6zn5:d, 6zoj:c, 6zol:c, 6zon:S, 6zp4:S, 6zuo:c, 6zv6:c, 6zvh:c, 6zvj:S, 6zvk:f3, 6zxd:c, 6zxe:c, 6zxf:c, 6zxg:c, 6zxh:c
4 8ip8:ua 64 61 0.7742 0.7500 0.7869 7.68e-28 8auv:L, 8b2l:L1, 8ip9:ua, 8ipa:ua, 8ipb:ua, 8jiw:Bc, 8r57:c, 4v7e:Bc
5 4v6w:Ac 62 62 0.7419 0.7419 0.7419 1.98e-27 6xu6:Ac, 6xu7:Ac, 6xu8:Ac
6 7qiy:M 64 58 0.7419 0.7188 0.7931 6.53e-27 7qiz:WA
7 5xyi:c 61 61 0.7419 0.7541 0.7541 1.09e-26
8 9bh5:Ac 65 62 0.7419 0.7077 0.7419 2.01e-26 9cai:Ac
9 6zj3:Sd 63 60 0.7097 0.6984 0.7333 4.14e-24
10 8br8:Sg 63 58 0.6935 0.6825 0.7414 8.18e-24 8brm:Sg, 8bsi:Sg, 8bsj:Sg, 8btd:Sg, 8btr:Sg, 8fvy:c, 8g4s:c, 7pwf:c, 7pwo:c1
11 5xxu:c 57 58 0.7097 0.7719 0.7586 4.60e-23
12 7ase:U 68 61 0.6935 0.6324 0.7049 9.85e-23 8a3w:Sd, 8a98:Sd, 6az1:d, 5opt:U, 8ovj:Sd, 8rxh:Sd, 8rxx:Sd, 5t2a:AZ, 4v8m:AZ
13 3j7a:5 58 58 0.6935 0.7414 0.7414 3.97e-22 3jbn:5, 3jbo:5, 3jbp:5, 6okk:e, 8tpu:S5
14 8ova:AZ 58 54 0.6452 0.6897 0.7407 2.74e-21 8ove:AZ
15 4v5o:A1 67 62 0.5968 0.5522 0.5968 2.27e-18 4bts:A1, 4bts:B1, 4bts:C1, 4bts:D1, 4v5o:B1
16 8hkx:S28E 63 59 0.6129 0.6032 0.6441 1.62e-16 8hky:S28E, 8hkz:S28E, 8hl1:S28E, 8hl2:S28E, 8hl3:S28E, 8hl4:S28E, 8hl5:S28E, 8wkp:S28E, 8wq2:S28E
17 5jb3:X 71 60 0.5806 0.5070 0.6000 3.30e-16 5jbh:X, 6skf:Ay, 6skg:Ay, 6sw9:X, 6swc:X, 6swe:X, 6th6:Ay, 4v4n:BX, 4v6u:AX, 7zag:X, 7zah:X, 7zai:X, 7zhg:X
18 6tmf:a 66 59 0.5806 0.5455 0.6102 9.95e-16
19 7qep:D8 57 56 0.4677 0.5088 0.5179 8.47e-12
20 6rm3:SCC 63 55 0.4516 0.4444 0.5091 7.06e-11
21 6zu5:SCC 55 55 0.3387 0.3818 0.3818 1.76e-07
22 6zww:C 749 61 0.3548 0.0294 0.3607 0.48 8po7:B, 8po8:A, 8po8:B, 6zww:A, 6zww:E, 6zww:G
23 8po7:A 594 61 0.3548 0.0370 0.3607 0.50
24 5t64:A 406 28 0.2258 0.0345 0.5000 1.4 5t64:B, 5t67:A, 5t67:B, 5t6b:A, 5t6b:B, 5t6b:C, 5t6b:D
25 5kvu:A 738 36 0.1935 0.0163 0.3333 3.6 5kvu:B, 5kvu:C, 5kvu:D
26 8fw1:A 362 34 0.1935 0.0331 0.3529 6.1 8fw1:B, 8fw1:C, 6myw:A, 6myw:B, 6myw:C, 6myw:D, 6o08:A, 8vcn:A
27 8smr:F 200 25 0.1774 0.0550 0.4400 6.7 8snh:F
28 4xhf:B 225 23 0.1613 0.0444 0.4348 9.7 4xhf:A, 4xhf:C, 4xhf:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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