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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PVKRRNNGRSKYNCGHTNIVRCQNCHRCVPKDKVIKRFTIRNIVDNTIADDVLNACVIQGFAIPKLYNKVQYCVSCSIHN
HIVRVRSREDRKIRTP

The query sequence (length=96) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8btd:Sd 108 96 1.0000 0.8889 1.0000 9.04e-66 8br8:Sd, 8brm:Sd, 8bsi:Sd, 8bsj:Sd, 8btr:Sd, 8fvy:a, 8g4s:a, 7pwf:a, 7pwo:a1
2 7pzy:b 100 96 0.6250 0.6000 0.6250 3.58e-37 8c3a:c, 8c3a:DN, 8cq7:c, 8cq7:DN, 8cqw:c, 8cqw:DN, 8cre:c, 8cre:DN, 8oeq:c, 8oeq:DN, 7q08:b, 7q0f:b, 7q0p:b, 7q0r:b, 8q5i:b
3 3j7a:3 95 94 0.6146 0.6211 0.6277 2.59e-36 3jbn:3, 3jbo:3, 3jbp:3, 6okk:c, 8tpu:S3
4 8auv:J 98 94 0.5521 0.5408 0.5638 4.25e-36 8b2l:J1, 7qix:N, 7qiz:DA
5 4v6w:Aa 107 94 0.5729 0.5140 0.5851 1.29e-35 6xu6:Aa, 6xu7:Aa, 6xu8:Aa
6 7olc:Sa 104 94 0.5625 0.5192 0.5745 3.72e-35 7old:Sa, 8oo0:Sa, 7r81:b2, 7z3n:Sa, 7z3o:Sa
7 6ip5:3C 107 94 0.5729 0.5140 0.5851 8.46e-35 7a01:O3, 7a09:Q, 5a2q:a, 5aj0:Ba, 9bdl:AS26, 9bdn:AS26, 9bdp:AS26, 8bhf:b3, 9bkd:Q, 9bln:Q, 8btk:AE, 7cpu:Sa, 7cpv:Sa, 4d5l:a, 4d61:a, 6d90:bb, 6d9j:bb, 9f1b:AE, 9f1c:AE, 9f1d:AE, 6fec:k, 5flx:a, 6g5h:a, 8g5y:Sa, 8g5z:Sa, 8g60:Sa, 8g61:Sa, 8g6j:Sa, 8glp:Sa, 6gz3:Ba, 6gz4:Ba, 6gz5:Ba, 6hcf:b1, 6hcj:b2, 6hcm:b1, 6hcq:b2, 8ifd:3C, 8ife:3C, 6ip6:3C, 6ip8:3C, 3j7p:Sa, 3j7r:Sa, 3jag:aa, 3jah:aa, 3jai:aa, 3jaj:Sa, 3jan:Sa, 8jdj:AM, 8jdk:AM, 8jdl:AM, 8jdm:AM, 7jqb:b, 7jqc:b, 5k0y:k, 8k2c:Sa, 7k5i:a, 4kzx:a, 4kzy:a, 4kzz:a, 5lks:Sa, 7ls1:F3, 7ls2:F3, 5lzs:aa, 5lzt:aa, 5lzu:aa, 5lzv:aa, 5lzw:aa, 5lzx:aa, 5lzy:aa, 5lzz:aa, 7mdz:aa, 6mtb:aa, 6mtc:aa, 6mtd:aa, 6mte:aa, 7nwg:b2, 7nwh:aa, 7nwi:aa, 7o7y:AE, 7o7z:AE, 7o80:AE, 7o81:AE, 5oa3:a, 6ole:Sa, 6olf:Sa, 6olg:Ba, 6oli:Sa, 6olz:Ba, 6om0:Sa, 6om7:Sa, 7oya:a2, 7oyb:a2, 7oyc:a2, 7oyd:Aa, 8oz0:R, 8p03:b, 8p09:b, 8p2k:AE, 6p4g:b, 6p4h:b, 6p5i:b, 6p5j:b, 6p5k:b, 6p5n:b, 8pj1:Q, 8pj2:Q, 8pj3:Q, 8pj4:Q, 8pj5:Q, 8pj6:Q, 8ppk:a, 8ppl:Aa, 8q7z:AE, 8q87:AE, 7qgg:Sa, 8qoi:Sa, 7qp6:Q, 7qp7:Q, 7qvp:Sa, 7qvp:Ra, 6qzp:Sa, 7r4x:a, 6r5q:LL, 6r6g:LL, 6r6p:ZZ, 6r7q:LL, 8rg0:Q, 8scb:aa, 6sgc:b1, 7syg:b, 7syh:b, 7syi:b, 7syj:b, 7syk:b, 7syl:b, 7sym:b, 7syn:b, 7syo:b, 7syp:b, 7syq:b, 7syr:b, 7sys:b, 7syt:b, 7syu:b, 7syv:b, 7syw:b, 7syx:b, 5t2c:AE, 8t4s:a, 7toq:AS26, 7tor:AS26, 7tql:c, 7ucj:Aa, 7uck:Aa, 4ug0:Sa, 4ujc:Ca, 4ujd:Ca, 4uje:Ba, 4v6x:Aa, 5vyc:a1, 5vyc:a2, 5vyc:a3, 5vyc:a4, 5vyc:a5, 5vyc:a6, 6w2s:b, 6w2t:b, 6xa1:Sa, 7xnx:Sa, 7xny:Sa, 8xsx:Sa, 8xsy:Sa, 8xsz:Sa, 8xxl:Sa, 8xxm:Sa, 8xxn:Sa, 6y0g:Sa, 8y0w:Sa, 8y0x:Sa, 6y2l:Sa, 6y57:Sa, 6yal:b, 6yam:b, 6yan:b, 6ybw:Q, 8yoo:Sa, 8yop:Sa, 6z6l:Sa, 6z6m:Sa, 6z6n:Sa, 7zjw:SF, 7zjx:SF, 6zlw:c, 6zm7:Sa, 6zme:Sa, 6zmi:Sa, 6zmo:Sa, 6zmw:Q, 6zn5:c, 6zoj:a, 6zok:a, 6zon:Q, 6zp4:Q, 6zv6:a, 6zvh:a, 6zvj:Q, 6zvk:O3, 6zxg:h, 6zxh:h
8 6fyx:a 103 96 0.5729 0.5340 0.5729 1.93e-33 7a1g:e, 7b7d:e, 8bn3:D6, 8bqd:e, 8bqx:e, 8cah:e, 8cas:e, 8ccs:2, 8cdl:2, 8cdr:2, 8ceh:2, 8cf5:2, 8cg8:2, 8cgn:2, 8civ:2, 8cku:2, 8cmj:2, 5dat:D6, 5dat:d6, 5dc3:D6, 5dc3:d6, 5dge:D6, 5dge:d6, 5dgf:D6, 5dgf:d6, 5dgv:D6, 5dgv:d6, 8eub:Ba, 8evp:Ba, 8evq:Ba, 8evr:Ba, 8evs:Ba, 8evt:Ba, 8ewb:Ba, 8ewc:Ba, 5fci:D6, 5fci:d6, 5fcj:D6, 5fcj:d6, 6fyy:a, 6gq1:AQ, 6gqb:AQ, 6gqv:AQ, 6gsm:a, 6gsn:a, 6hhq:b, 6hhq:d6, 5i4l:D6, 5i4l:d6, 6i7o:e, 6i7o:eb, 8i7j:a, 5it7:a, 5it9:a, 3j6x:26, 3j6y:26, 3j77:26, 3j78:26, 3j80:a, 3j81:a, 3jam:a, 3jap:a, 5juo:XB, 5jup:XB, 5jus:XB, 5jut:XB, 5juu:XB, 8k2d:Sa, 8k82:Sa, 5ll6:e, 5lyb:D6, 5lyb:d6, 5m1j:a2, 5mc6:e, 5mei:d6, 5mei:b, 7mpi:Ba, 7mpj:Ba, 7n8b:Ba, 5ndg:D6, 5ndg:d6, 5ndv:D6, 5ndv:d6, 5ndw:D6, 5ndw:d6, 7nrc:Se, 7nrd:Se, 5obm:D6, 5obm:d6, 5on6:d6, 5on6:b, 7osa:eS26, 7osm:eS26, 6q8y:e, 7rr5:Sa, 8rw1:a, 6s47:Bb, 8s8d:a, 8s8e:a, 8s8f:a, 8s8g:a, 8s8h:a, 8s8i:a, 8s8j:a, 6snt:a, 6sv4:e, 6sv4:eb, 6sv4:ec, 6t4q:Sa, 6t7i:Sa, 6t7t:Sa, 6t83:ab, 6t83:1, 5tbw:b, 5tbw:d6, 6tb3:e, 5tga:D6, 5tga:d6, 5tgm:D6, 5tgm:d6, 6tnu:e, 4u3m:D6, 4u3m:d6, 4u3n:D6, 4u3n:d6, 4u3u:D6, 4u3u:d6, 4u4n:D6, 4u4n:d6, 4u4o:D6, 4u4o:d6, 4u4q:D6, 4u4q:d6, 4u4r:D6, 4u4r:d6, 4u4u:D6, 4u4u:d6, 4u4y:D6, 4u4y:d6, 4u4z:D6, 4u4z:d6, 4u50:D6, 4u50:d6, 4u51:D6, 4u51:d6, 4u52:D6, 4u52:d6, 4u53:D6, 4u53:d6, 4u55:D6, 4u55:d6, 4u56:D6, 4u56:d6, 4u6f:D6, 4u6f:d6, 4uer:5, 6uz7:a, 4v88:Aa, 4v88:Ca, 4v8y:A0, 4v8z:A0, 4v92:Ba, 6woo:aa, 6xiq:AQ, 6xir:AQ, 8y0u:Sa, 6z6j:Sa, 6z6k:Sa, 6zce:b, 7zpq:Aa, 7zrs:Aa, 6zu9:e, 7zuw:Aa, 7zux:Da, 6zvi:K, 7zw0:se
9 6zj3:Sb 97 96 0.5625 0.5567 0.5625 1.23e-32
10 5xxu:a 99 94 0.5521 0.5354 0.5638 3.09e-32
11 9bh5:Aa 99 95 0.5104 0.4949 0.5158 1.54e-31 9cai:Aa
12 6zu5:SAA 97 95 0.4896 0.4845 0.4947 1.57e-30
13 4bts:A5 100 98 0.5417 0.5200 0.5306 3.02e-30 4bts:B5, 4bts:C5, 4bts:D5, 4v5o:A5, 4v5o:B5
14 8p5d:SAA 101 92 0.5000 0.4752 0.5217 9.81e-30 8p60:SAA, 8p60:RAA, 7qca:SAA
15 5xyi:a 100 81 0.5104 0.4900 0.6049 1.74e-29
16 8jiw:Ba 98 80 0.4792 0.4694 0.5750 7.95e-29 8ip8:db, 8ip9:db, 8ipa:db, 8ipb:db, 8r6f:a, 4v7e:Ba
17 6rm3:SAA 97 94 0.5000 0.4948 0.5106 4.55e-26
18 8ova:AV 103 97 0.5000 0.4660 0.4948 1.38e-25 8ove:AV, 4v8m:AV
19 7qep:D6 101 91 0.4271 0.4059 0.4505 1.30e-23
20 7ase:t 104 97 0.4583 0.4231 0.4536 4.99e-23 5opt:T
21 8rxh:Sb 104 97 0.4375 0.4038 0.4330 5.33e-22 8a3w:Sb, 8a98:Sb, 6az1:b, 8ovj:Sb, 8rxx:Sb, 5t2a:AV
22 7olc:LD 300 50 0.1458 0.0467 0.2800 0.13 8i9r:LD, 7old:LD, 8oo0:LD, 8pv1:LD, 8pv2:LD, 8pv3:LD, 8pv4:LD, 8pv5:LD, 8pv6:LD, 8pv7:LD, 8pv8:LD, 8pvk:LD, 8pvl:LD, 7z3n:LD, 7z3o:LD
23 7r81:G1 300 50 0.1458 0.0467 0.2800 0.24
24 7ozs:A 275 51 0.1458 0.0509 0.2745 0.35
25 5it7:DD 295 59 0.1875 0.0610 0.3051 0.45 6uz7:AD
26 4xiv:B 252 53 0.1250 0.0476 0.2264 1.1 4xiv:A
27 4v6i:BQ 297 59 0.1875 0.0606 0.3051 1.7 8aaf:m, 8agt:m, 8agu:m, 8agv:m, 8agw:m, 8agx:m, 8agz:m, 5apn:D, 5apo:D, 7azy:t, 7b7d:LG, 8bip:LD, 8bjq:LD, 8bn3:L5, 8bqd:BI, 8bqx:BI, 7bt6:D, 7btb:D, 8ccs:HH, 8cdl:HH, 8cdr:HH, 8ceh:HH, 8cf5:HH, 8cg8:HH, 8cgn:HH, 8civ:HH, 8cku:HH, 8cmj:HH, 5dat:L5, 5dat:l5, 5dc3:L5, 5dc3:l5, 5dge:L5, 5dge:l5, 5dgf:L5, 5dgf:l5, 5dgv:L5, 5dgv:l5, 8eub:AD, 8evp:AD, 8evq:AD, 8evr:AD, 8evs:AD, 8evt:AD, 8ewb:AD, 8ewc:AD, 5fci:L5, 5fci:l5, 5fcj:L5, 5fcj:l5, 6ft6:D, 5gak:H, 6gq1:D, 6gqb:D, 6gqv:D, 5h4p:D, 6hd7:H, 8hfr:Ez, 6hhq:m, 6hhq:CG, 5i4l:L5, 5i4l:l5, 6i7o:BI, 6i7o:YI, 3j6x:L5, 3j6y:L5, 3j77:L5, 3j78:L5, 3jct:D, 5jcs:D, 5juo:I, 5jup:I, 5jus:I, 5jut:I, 5juu:I, 8k2d:LD, 8k82:LD, 5lyb:L5, 5lyb:l5, 5m1j:D5, 6m62:D, 5mc6:BI, 5mei:m, 5mei:CG, 7mpi:AD, 7mpj:AD, 6n8j:D, 6n8m:G, 6n8n:G, 6n8o:G, 7n8b:AD, 5ndg:L5, 5ndg:l5, 5ndv:L5, 5ndv:l5, 5ndw:L5, 5ndw:l5, 7nrc:LG, 7nrd:LG, 5obm:L5, 5obm:l5, 7oh3:D, 7ohq:D, 7oht:D, 6oig:D, 5on6:m, 5on6:CG, 7osa:uL18, 7osm:uL18, 8p8m:LI, 8p8n:LI, 8p8u:LI, 8pfr:LI, 6q8y:BI, 6qik:P, 6qt0:P, 6qtz:P, 6r84:H, 6r86:H, 6r87:H, 6ri5:P, 7rr5:LD, 6rzz:P, 6s05:P, 6s47:AG, 6snt:k, 6sv4:BI, 6sv4:YI, 6sv4:ZI, 6t4q:LD, 5t62:G, 5t6r:G, 6t7i:LD, 6t7t:LD, 6t83:Dy, 6t83:Ga, 5tbw:m, 5tbw:CG, 6tb3:BI, 5tga:L5, 5tga:l5, 5tgm:L5, 5tgm:l5, 6tnu:BI, 7too:AL05, 7top:AL05, 4u3m:L5, 4u3m:l5, 4u3n:L5, 4u3n:l5, 4u3u:L5, 4u3u:l5, 4u4n:L5, 4u4n:l5, 4u4o:L5, 4u4o:l5, 4u4q:L5, 4u4q:l5, 4u4r:L5, 4u4r:l5, 4u4u:L5, 4u4u:l5, 4u4y:L5, 4u4y:l5, 4u4z:L5, 4u4z:l5, 4u50:L5, 4u50:l5, 4u51:L5, 4u51:l5, 4u52:L5, 4u52:l5, 4u53:L5, 4u53:l5, 4u55:L5, 4u55:l5, 4u56:L5, 4u56:l5, 4u6f:L5, 4u6f:l5, 7ug6:D, 7uoo:D, 7uqb:D, 7uqz:D, 7v08:D, 4v4b:BE, 4v7h:BE, 4v7r:BE, 4v7r:DE, 4v88:BD, 4v88:DD, 4v8t:D, 4v8y:BD, 4v8z:BD, 4v91:D, 6woo:D, 6xiq:D, 6xir:D, 8y0u:LD, 7z34:D, 6z6j:LD, 6z6k:LD, 7zpq:BD, 7zrs:BD, 7zs5:BF, 7zuw:BD, 7zux:ED, 7zw0:LH
28 4v7f:P 269 61 0.1771 0.0632 0.2787 1.9 6n8k:D, 6n8l:D, 6ylg:D, 6ylh:D
29 2i1o:A 389 13 0.0729 0.0180 0.5385 7.9 1yte:A, 1ytk:A
30 5dzy:B 415 26 0.1250 0.0289 0.4615 9.5 5dzx:A, 5dzx:B, 5dzy:D, 5dzy:A, 5dzy:C, 5dzy:E, 5dzy:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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