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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVD
VVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHP
SYRHAAAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRV
AAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGL
RRASAAIDTGAAEQLLARWVRFGRQILE

The query sequence (length=348) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5c2l:A 349 347 0.9971 0.9943 1.0000 0.0 5bne:A, 5bne:B, 5bne:D, 5bo2:A, 5bo2:B, 5bo3:A, 5bo3:B, 2bpq:A, 2bpq:B, 5byt:A, 5byt:B, 5c1r:A, 5c1r:B, 5c7s:A, 5c7s:B, 4giu:A, 4giu:B, 4gkm:A, 4gkm:B, 4ij1:A, 4ij1:B, 4m0r:A, 4m0r:B, 4n5v:A, 4n5v:B, 4n8q:A, 4n8q:B, 4n93:A, 4n93:B, 4owm:A, 4owm:B, 4own:A, 4own:B, 4owo:A, 4owo:B, 4owq:A, 4owq:B, 4ows:A, 4ows:B, 4owu:A, 4owu:B, 4owv:A, 4owv:B, 3qqs:A, 3qqs:B, 3qqs:C, 3qqs:D, 3qs8:A, 3qs8:B, 3qs8:C, 3qs8:D, 3qsa:A, 3qsa:B, 3r6c:A, 3r6c:B, 3r88:A, 3r88:B, 3twp:A, 3twp:B, 3twp:C, 3twp:D, 3uu1:A, 3uu1:B, 3uu1:C, 3uu1:D, 4x58:A, 4x59:A, 4x59:B, 4x5b:A, 4x5b:B, 4x5c:A, 4x5c:B, 4x5d:A, 4x5d:B, 4x5e:A, 4x5e:B, 4zof:A, 4zof:B, 4zoj:A, 4zoj:B, 4zok:A, 4zok:B, 4ztv:A, 4ztv:B, 1zvw:A
2 1kgz:B 330 280 0.2787 0.2939 0.3464 3.46e-51 1kgz:A
3 4yi7:A 331 356 0.3333 0.3505 0.3258 5.61e-46
4 2gvq:D 345 300 0.2816 0.2841 0.3267 1.29e-44 3gbr:A, 3gbr:B, 2gvq:A, 2gvq:B, 2gvq:C, 1gxb:A, 1gxb:B, 1gxb:C, 1gxb:D, 1zxy:A, 1zxy:B, 1zxy:C, 1zxy:D, 1zyk:A, 1zyk:B, 1zyk:C, 1zyk:D
5 5nof:A 325 335 0.3247 0.3477 0.3373 3.37e-43 5nof:B
6 7dsj:A 363 322 0.2730 0.2617 0.2950 8.26e-35 7dsj:B, 7dso:A, 7dsp:B, 7dsp:A, 7dsr:A
7 4ga6:A 493 149 0.1063 0.0751 0.2483 0.002 4ga4:A, 4ga4:B, 4ga6:B
8 5oln:B 434 135 0.0977 0.0783 0.2519 0.25 5oln:A
9 5n2n:A 149 70 0.0632 0.1477 0.3143 0.51 3mmn:A
10 1v9l:A 418 131 0.1006 0.0837 0.2672 1.0 1v9l:B, 1v9l:C, 1v9l:D, 1v9l:E, 1v9l:F
11 3und:B 284 67 0.0603 0.0739 0.3134 2.0 3tmq:A, 3tmq:C, 3und:A, 3und:C, 3und:D
12 5cjp:E 372 77 0.0632 0.0591 0.2857 3.8 5cjp:F
13 6js9:A 180 75 0.0546 0.1056 0.2533 4.4 6js9:B
14 8bft:A 321 182 0.1121 0.1215 0.2143 4.6
15 7w6m:A 1224 65 0.0546 0.0155 0.2923 5.5 7w6m:C, 7w6m:B, 7w73:C, 7w73:A, 7y6t:B, 7y6u:A
16 7y6t:C 1098 65 0.0546 0.0173 0.2923 5.8
17 7y6t:A 1124 65 0.0546 0.0169 0.2923 5.8
18 6fxj:A 251 50 0.0489 0.0677 0.3400 8.3 6fxj:B, 6fxj:C, 6fxj:D, 6fxj:E, 6fxq:A, 6fxq:B, 6fxq:C, 6fxq:D, 6fxq:E, 5loq:A, 5loq:B, 5loq:C, 5loq:D, 5loq:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218