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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PSEAGHRLYVKGRHLSYQRGRRNTHPKTSLIKIEGVDDTAAANFYLGKRVAYVYRAQKEVRGTKIRVIWGKITRPHGNSG
VVRAKFTHPLPARSFGASVRIMLYPSS

The query sequence (length=107) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8i9p:Lf 108 107 1.0000 0.9907 1.0000 7.34e-76 8i9r:Lf, 8i9t:Lf, 8i9v:Lf, 8i9w:Lf, 8i9x:Lf, 8i9y:Lf, 8i9z:Lf, 8ia0:Lf, 7olc:Lf, 7old:Lf, 8oo0:Lf, 8pv1:Lf, 8pv2:Lf, 8pv3:Lf, 8pv4:Lf, 8pv5:Lf, 8pv6:Lf, 8pv7:Lf, 8pv8:Lf, 8pvk:Lf, 8pvl:Lf, 7r81:h1, 7z3n:Lf, 7z3o:Lf
2 8aaf:S 106 102 0.6916 0.6981 0.7255 1.43e-50 8agt:S, 8agu:S, 8agv:S, 8agw:S, 8agx:S, 8agz:S, 5apn:f, 5apo:f, 7azy:v, 7b7d:Lb, 8bip:Lf, 8bjq:Lf, 8bn3:O3, 8bqd:BK, 8bqx:BK, 7bt6:f, 7btb:f, 6c0f:f, 6cb1:f, 8ccs:R, 8cdl:R, 8cdr:R, 8ceh:R, 8cf5:R, 8cg8:R, 8cgn:R, 8civ:R, 8cku:R, 8cmj:R, 5dat:O3, 5dat:o3, 5dc3:O3, 5dc3:o3, 5dge:O3, 5dge:o3, 5dgf:O3, 5dgf:o3, 5dgv:O3, 5dgv:o3, 6elz:f, 6em1:f, 6em3:f, 6em4:f, 6em5:f, 8eub:Af, 8evp:Af, 8evq:Af, 8evr:Af, 8evs:Af, 8evt:Af, 8ewb:Af, 8ewc:Af, 5fci:O3, 5fci:o3, 5fcj:O3, 5fcj:o3, 6ft6:f, 5gak:h, 6gq1:f, 6gqb:f, 6gqv:f, 5h4p:f, 6hd7:h, 8hfr:f7, 6hhq:AG, 6hhq:DH, 5i4l:O3, 5i4l:o3, 6i7o:BK, 6i7o:YK, 3j6x:73, 3j6y:73, 3j77:83, 3j78:83, 3jct:f, 5jcs:f, 5juo:KA, 5jup:KA, 5jus:KA, 5jut:KA, 5juu:KA, 8k2d:Lf, 8k82:Lf, 5lyb:O3, 5lyb:o3, 5m1j:f5, 6m62:f, 5mc6:BK, 5mei:AG, 5mei:DH, 7mpi:Af, 7mpj:Af, 6n8j:f, 6n8k:f, 6n8l:f, 6n8m:s, 6n8n:s, 6n8o:s, 7n8b:Af, 7nac:f, 5ndg:O3, 5ndg:o3, 5ndv:O3, 5ndv:o3, 5ndw:O3, 5ndw:o3, 7nrc:Lh, 7nrd:Lh, 5obm:O3, 5obm:o3, 7of1:f, 7oh3:f, 7ohp:f, 7ohq:f, 7ohr:f, 7ohs:f, 7oht:f, 7ohu:f, 7ohv:f, 7ohw:f, 7ohx:f, 7ohy:f, 6oig:f, 5on6:AG, 5on6:DH, 7osa:eL33, 7osm:eL33, 8p8m:RF, 8p8n:RF, 8p8u:RF, 8pfr:RF, 6q8y:BK, 6qik:f, 6qt0:f, 6qtz:f, 7r7a:f, 6r84:h, 6r86:h, 6r87:h, 6ri5:f, 7rr5:Lf, 6rzz:f, 6s05:f, 6s47:Ah, 6snt:ak, 6sv4:BK, 6sv4:YK, 6sv4:ZK, 6t4q:Lf, 5t62:s, 5t6r:s, 6t7i:Lf, 6t7t:Lf, 6t83:fy, 6t83:Q, 5tbw:AG, 5tbw:DH, 6tb3:BK, 5tga:O3, 5tga:o3, 5tgm:O3, 5tgm:o3, 6tnu:BK, 7too:AL33, 7top:AL33, 7u0h:f, 4u3m:O3, 4u3m:o3, 4u3n:O3, 4u3n:o3, 4u3u:O3, 4u3u:o3, 4u4n:O3, 4u4n:o3, 4u4o:O3, 4u4o:o3, 4u4q:O3, 4u4q:o3, 4u4r:O3, 4u4r:o3, 4u4u:O3, 4u4u:o3, 4u4y:O3, 4u4y:o3, 4u4z:O3, 4u4z:o3, 4u50:O3, 4u50:o3, 4u51:O3, 4u51:o3, 4u52:O3, 4u52:o3, 4u53:O3, 4u53:o3, 4u55:O3, 4u55:o3, 4u56:O3, 4u56:o3, 4u6f:O3, 4u6f:o3, 7ug6:f, 7uoo:f, 7uqb:f, 7uqz:f, 7v08:f, 4v6i:Bj, 4v7f:e, 4v88:Bf, 4v88:Df, 4v8t:f, 4v8y:Bf, 4v8z:Bf, 8v83:f, 8v84:f, 8v87:f, 4v91:f, 6woo:f, 6xiq:f, 6xir:f, 8y0u:Lf, 6ylg:f, 6ylh:f, 6ylx:f, 6yly:f, 5z3g:j, 7z34:f, 6z6j:Lf, 6z6k:Lf, 7zpq:Be, 7zrs:Be, 7zs5:Bg, 7zuw:Be, 7zux:Ee, 7zw0:Li
3 8esq:f 106 103 0.6355 0.6415 0.6602 7.48e-50 8esr:f, 8etc:f, 8etg:f, 8eth:f, 8eti:f, 8etj:f, 8eug:f, 8eui:f, 8eup:f, 8euy:f, 8ev3:f
4 5it7:ff 105 102 0.6822 0.6952 0.7157 2.68e-49 6uz7:Bf
5 8c3a:AG 106 102 0.6542 0.6604 0.6863 1.86e-48 8c3a:CA, 8cq7:AG, 8cq7:CA, 8cqw:AG, 8cqw:CA, 8cre:AG, 8cre:CA, 8oeq:AG, 8oeq:CA, 7pzy:AG, 7q08:AG, 7q0f:AG, 7q0p:AG, 7q0r:AG, 8q5i:AG
6 8e5t:f 88 102 0.5981 0.7273 0.6275 3.52e-37
7 8azw:S 111 101 0.5047 0.4865 0.5347 4.99e-37 8b2l:S3, 7qiw:h, 7qiz:h
8 4v7e:Cf 111 101 0.5140 0.4955 0.5446 6.90e-36 8jiv:Cf, 4v3p:Lj
9 8ip8:MB 110 101 0.5047 0.4909 0.5347 3.46e-35 8ipa:MB, 8ipb:MB
10 5xxb:e 105 101 0.5327 0.5429 0.5644 5.28e-35
11 3j79:9 103 99 0.5047 0.5243 0.5455 6.81e-34 3jbn:A9, 3jbo:A9, 3jbp:A9, 8tpu:A9, 5umd:9
12 7oya:f1 107 105 0.5140 0.5140 0.5238 8.14e-33 7oyb:f1
13 8btk:Bf 110 105 0.5140 0.5000 0.5238 1.19e-31 7a01:x2, 8a3d:Z, 5aj0:Af, 8b5l:f, 8b6c:f, 9bdl:AL33, 9bdn:AL33, 9bdp:AL33, 7bhp:Lf, 8bhf:S1, 8bpo:e2, 7cpu:Lf, 7cpv:Lf, 4d5y:f, 4d67:f, 6d90:f, 6d9j:f, 9f1b:Bf, 9f1c:Bf, 9f1d:Bf, 7f5s:Lf, 8fkp:LT, 8fkq:LT, 8fkr:LT, 8fks:LT, 8fkt:LT, 8fku:LT, 8fkv:LT, 8fkw:LT, 8fkx:LT, 8fky:LT, 8fkz:LT, 8fl0:LT, 8fl2:LT, 8fl3:LT, 8fl4:LT, 8fl6:LT, 8fl7:LT, 8fl9:LT, 8fla:LT, 8flb:LT, 8flc:LT, 8fld:LT, 8fle:LT, 8flf:LT, 6frk:f, 6ftg:f, 6fti:f, 6ftj:f, 8g5y:Lf, 8g5z:Lf, 8g60:Lf, 8g61:Lf, 8g6j:Lf, 8glp:Lf, 6gz3:Af, 6gz4:Af, 6gz5:Af, 6hcf:f3, 6hcj:f3, 6hcm:f3, 6hcq:f3, 8idt:n, 8idy:n, 8ie3:n, 8ifd:2Z, 8ife:2Z, 8ine:n, 8inf:n, 8ink:n, 6ip5:2Z, 6ip6:2Z, 6ip8:2Z, 8ipd:n, 8ipx:n, 8ipy:n, 8ir1:n, 8ir3:n, 3j7o:f, 3j7p:f, 3j7q:f, 3j7r:f, 3j92:f, 3jag:f, 3jah:f, 3jai:f, 3jaj:f, 3jan:f, 8jdj:k, 8jdk:k, 8jdl:k, 8jdm:k, 8k2c:Lf, 5lks:Lf, 6lqm:u, 6lsr:u, 6lss:n, 7ls1:Z2, 7ls2:Z2, 6lu8:n, 5lzs:f, 5lzt:f, 5lzu:f, 5lzv:f, 5lzw:f, 5lzx:f, 5lzy:f, 5lzz:f, 7mdz:f, 6mtb:f, 6mtc:f, 6mtd:f, 6mte:f, 7nfx:f, 7nwg:f3, 7nwh:f, 7nwi:f, 7o7y:Bf, 7o7z:Bf, 7o80:Bf, 7o81:Bf, 7obr:f, 8ohd:Lf, 8oj0:Lf, 8oj5:Lf, 8oj8:Lf, 6ole:g, 6olf:g, 6olg:Af, 6oli:g, 6olz:Af, 6om0:g, 6om7:g, 7ow7:Z, 7oyc:f1, 7oyd:f, 8p2k:Bf, 6p5i:Af, 6p5j:Af, 6p5k:Af, 6p5n:Af, 8q7z:Bf, 8q87:Bf, 8qfd:f, 7qgg:g, 8qoi:Lf, 7qvp:Lf, 7qvp:Mf, 7qwq:f, 7qwr:f, 7qws:f, 6qzp:Lf, 6r5q:f, 6r6g:f, 6r6p:f, 6r7q:f, 8rjb:f, 8rjc:f, 8rjd:f, 8scb:f, 6sgc:f2, 6swa:d, 5t2c:Z, 6t59:f3, 7tm3:f, 7toq:AL33, 7tor:AL33, 7tut:f, 7ucj:f, 7uck:f, 4ug0:Lf, 4ujc:Bf, 4ujd:Af, 4uje:Cf, 4v6x:Cf, 6w6l:g, 6xa1:Lf, 7xnx:Lf, 7xny:Lf, 8xsx:Lf, 8xsy:Lf, 8xsz:Lf, 6y0g:Lf, 8y0w:Lf, 8y0x:Lf, 6y2l:Lf, 6y57:Lf, 6y6x:Lf, 8yoo:Lf, 8yop:Lf, 6z6l:Lf, 6z6m:Lf, 6z6n:Lf, 7zjw:Li, 7zjx:Li, 6zm7:Lf, 6zme:Lf, 6zmi:Lf, 6zmo:Lf, 6zvk:x2
14 9bh5:Cf 117 107 0.4860 0.4444 0.4860 2.20e-30 9cai:Cf
15 4v6w:Cf 157 107 0.4579 0.3121 0.4579 2.51e-28 6xu6:Cf, 6xu7:Cf, 6xu8:Cf
16 4v8p:AH 107 100 0.3738 0.3738 0.4000 1.04e-24 4v8p:DH, 4v8p:FH, 4v8p:HH
17 5xy3:f 97 101 0.4206 0.4639 0.4455 3.71e-24
18 8ova:Bl 144 111 0.4673 0.3472 0.4505 3.74e-24 8ove:Bl, 4v8m:Bl
19 8rxh:Lg 143 111 0.4112 0.3077 0.3964 1.27e-22 8a3w:g, 8a98:g, 6az3:g, 3jcs:g, 8ovj:g, 8rxx:Lg, 5t2a:j
20 5t5h:l 136 111 0.4486 0.3529 0.4324 1.75e-22
21 6zj3:Lv 114 108 0.4112 0.3860 0.4074 2.91e-22
22 6zu5:LFF 104 90 0.3832 0.3942 0.4556 1.56e-16
23 7pwg:f 123 101 0.2991 0.2602 0.3168 5.10e-12 8br8:Lg, 8brm:Lg, 8bsi:Lg, 8bsj:Lg, 8btd:Lg, 8btr:Lg, 8fru:f, 7pwo:f2
24 8p5d:LFF 111 102 0.3551 0.3423 0.3725 6.73e-12 8p60:LFF, 8p60:KFF, 7qca:LFF
25 7qep:O3 109 101 0.3458 0.3394 0.3663 4.76e-11
26 4v6u:Bc 87 95 0.2804 0.3448 0.3158 1.70e-09
27 6rm3:LFF 96 97 0.2804 0.3125 0.3093 1.45e-06
28 6skg:Bf 86 88 0.2523 0.3140 0.3068 5.11e-05
29 8a98:H 221 65 0.1776 0.0860 0.2923 1.7 8a3w:H, 6az3:H, 3jcs:H, 8ovj:H, 8rxh:LH, 8rxx:LH, 5t2a:M
30 8tpt:B 571 59 0.1963 0.0368 0.3559 2.3
31 6qm5:A 673 55 0.1682 0.0267 0.3273 3.0 6qm5:B, 6qm9:A, 6qm9:B, 6qma:A, 6qma:B, 6qmb:A, 6qmb:B, 8toi:A, 8toi:B, 8tok:A, 8tok:B, 8tol:A, 8tol:B, 4wis:A, 4wis:B, 4wit:A, 4wit:B
32 8tpm:B 615 45 0.1589 0.0276 0.3778 4.1 8tpm:A, 8tpo:B, 8tpo:A, 8tpp:A, 8tpp:B, 8tpr:A, 8tpr:B
33 6a5e:A 375 32 0.1028 0.0293 0.3438 7.2 6a5e:B
34 3ukg:A 223 59 0.1589 0.0762 0.2881 7.5 4gfb:A, 1ign:A, 1ign:B, 6ldm:A
35 5t5h:O 202 65 0.1869 0.0990 0.3077 7.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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