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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PRLYFENRSKFIQDQKDKGINPYPHKFERTISIPEFIEKYKDLGNGEHLEDTILNITGRIMRVSASGQKLRFFDLVGDGE
KIQVLANYSFHNHEKGNFAECYDKIRRGDIVGIVGFPGKSKKGELSIFPKETILLSACLHMLPMKYGLKDTEIRYRQRYL
DLLINESSRHTFVTRTKIINFLRNFLNERGFFEVETPMMNLIAGGANARPFITHHNDLDLDLYLRIATELPLKMLIVGGI
DKVYEIGKVFRNEGIDNTHNPEFTSCEFYWAYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQPIEIDFTPPYP
KVSIVEEIEKVTNTILEQPFDSNETIEKMINIIKEHKIELPNPPTAAKLLDQLASHFIENKYNDKPFFIVEHPQIMSPLA
KYHRTKPGLTERLEMFICGKEVLNAYTELNDPFKQKECFQLDSAFCTSLEYGLPPTGGLGLGIDRITMFLTNKNSIKDVI
LFPTMRP

The query sequence (length=487) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6agt:B 506 502 1.0000 0.9625 0.9701 0.0 6agt:A, 6agt:C, 6agt:D, 7bt5:A, 7bt5:B, 6hcu:A, 6hcu:B, 6hcv:A, 6hcv:B, 8k9s:A, 8k9s:B, 8k9u:A, 8k9u:B, 8k9v:A, 8k9v:B, 8k9w:A, 8k9w:B, 8k9x:A, 8k9x:B, 6ka6:A, 6ka6:B, 6ka6:C, 6ka6:D, 6kab:A, 6kab:B, 6kab:C, 6kab:D, 6kbf:A, 6kbf:B, 6kcn:A, 6kcn:B, 6kcn:C, 6kcn:D, 6kct:A, 6kct:B, 6kct:C, 6kct:D, 6l3y:B, 6l3y:A, 6l4q:B, 6l4q:A, 6m0t:A, 6m0t:B, 6m0t:C, 6m0t:D, 4pg3:A, 4pg3:B, 4pg3:C, 4pg3:D, 4ycv:A, 4ycv:B, 4ycv:C, 4ycv:D, 5zh2:B, 5zh3:A, 5zh3:B, 5zh4:A, 5zh4:B, 5zh5:A, 5zh5:B
2 5zh2:A 464 487 0.9466 0.9935 0.9466 0.0
3 6bni:A 502 499 0.5565 0.5398 0.5431 0.0 6bni:B, 6c86:A, 6c86:B, 5eln:A, 5eln:B, 5eln:C, 5eln:D, 5elo:A, 5elo:B, 5elo:C, 5elo:D, 6hcw:A, 6hcw:B, 7zog:A, 7zog:B, 7zog:C, 7zog:D
4 6chd:A 506 505 0.5585 0.5375 0.5386 0.0 3bju:A, 3bju:B, 3bju:C, 3bju:D, 6chd:B, 4dpg:A, 4dpg:B, 4dpg:C, 4dpg:D, 4dpg:E, 4dpg:F, 4dpg:G, 4dpg:H, 7ea9:A, 7ea9:B, 7ea9:C, 7ea9:D, 6ild:A, 6ild:B, 6ilh:A, 6ilh:B, 4ycu:A, 4ycu:B, 4ycw:A, 4ycw:B, 4ycw:E, 4ycw:F
5 5hgq:B 482 490 0.5421 0.5477 0.5388 0.0 5hgq:A, 5hgq:D, 5hgq:C
6 7f6w:A 506 511 0.5113 0.4921 0.4873 4.02e-170
7 4up7:A 529 503 0.4682 0.4310 0.4533 3.46e-153 4up9:A, 4upa:A
8 3a74:A 484 487 0.4251 0.4277 0.4251 1.45e-119 3a74:B, 3a74:C, 3a74:D, 3e9h:A, 3e9h:B, 3e9h:C, 3e9h:D, 3e9i:A, 3e9i:B, 3e9i:C, 3e9i:D
9 1e1t:A 485 504 0.4271 0.4289 0.4127 1.59e-115 1e1o:A, 1e22:A, 1e24:A, 1lyl:A, 1lyl:B, 1lyl:C, 5yzx:A, 5yzx:B, 5yzx:C
10 1bbu:A 486 504 0.4189 0.4198 0.4048 4.07e-109
11 4ex5:A 486 504 0.3840 0.3848 0.3710 3.70e-98 4ex5:B
12 6aqg:C 490 502 0.3655 0.3633 0.3546 9.19e-98 6aqg:A, 6aqg:B, 6aqg:D, 5vl1:A, 5vl1:B, 5vl1:C, 5vl1:D
13 6wbd:B 485 510 0.3819 0.3835 0.3647 4.43e-97 6wbd:A
14 6nrz:A 517 516 0.3778 0.3559 0.3566 5.04e-96 6nrz:B, 6ns0:A, 6ns0:B, 6o3f:A, 6o3f:B
15 6aqh:B 490 506 0.3552 0.3531 0.3419 2.61e-86 6aqh:A, 6aqh:C, 6aqh:D
16 7qh8:A 471 501 0.3511 0.3631 0.3413 1.75e-79 7qhn:A, 7qi8:A
17 3a5z:C 324 336 0.1725 0.2593 0.2500 1.40e-23 3a5y:B, 3a5y:C, 3a5y:D, 3a5z:A, 3a5z:E, 3a5z:G, 3g1z:A, 3g1z:B
18 3a5y:A 297 336 0.1663 0.2727 0.2411 5.38e-22
19 1b8a:A 438 410 0.2115 0.2352 0.2512 9.52e-19 1b8a:B, 3nel:A, 3nem:A, 3nem:B
20 1asy:A 490 349 0.1622 0.1612 0.2264 2.30e-12 1asy:B, 1asz:A, 1asz:B
21 4wj3:M 589 139 0.0842 0.0696 0.2950 3.59e-11 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
22 4wj3:M 589 87 0.0575 0.0475 0.3218 1.77e-07 4wj3:N, 4wj3:O, 4wj3:P, 4wj4:A
23 1c0a:A 585 174 0.0986 0.0821 0.2759 1.72e-10 1il2:A, 1il2:B
24 1c0a:A 585 50 0.0493 0.0410 0.4800 1.61e-06 1il2:A, 1il2:B
25 5w25:A 583 181 0.0986 0.0823 0.2652 5.55e-10 5w25:B
26 5w25:A 583 33 0.0329 0.0274 0.4848 0.001 5w25:B
27 6sjc:B 581 157 0.0780 0.0654 0.2420 5.83e-10 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
28 6sjc:B 581 109 0.0719 0.0602 0.3211 9.89e-08 7ap4:A, 7ap4:B, 1efw:A, 1efw:B, 1g51:A, 1g51:B, 6hhv:A, 6hhv:B, 6hhw:A, 6hhw:B, 6hhx:A, 6hhx:B, 6sjc:A
29 4o2d:B 515 180 0.0986 0.0932 0.2667 1.09e-08
30 4o2d:B 515 54 0.0472 0.0447 0.4259 3.91e-05
31 4o2d:A 580 180 0.0986 0.0828 0.2667 1.21e-08 4rmf:A
32 4o2d:A 580 54 0.0472 0.0397 0.4259 4.65e-05 4rmf:A
33 3kfu:C 377 378 0.1602 0.2069 0.2063 8.06e-08 3kfu:A, 3kfu:D, 3kfu:B
34 2xgt:B 433 163 0.0965 0.1085 0.2883 3.19e-06 2xgt:A, 2xti:A, 2xti:B
35 1x54:A 434 347 0.1643 0.1843 0.2305 2.26e-05 1x55:A
36 3m4p:A 435 353 0.1458 0.1632 0.2011 2.35e-05 3m4p:B, 3m4p:C, 3m4p:D
37 8tc8:A 435 468 0.2053 0.2299 0.2137 5.77e-05 8h53:A, 8h53:B, 8h53:C, 8h53:D, 8tc8:B, 8tc8:C, 8tc8:D, 8tc9:A, 8tc9:B, 8tc9:C, 8tc9:D
38 3p8v:A 294 331 0.1396 0.2313 0.2054 0.032 3p8v:B, 3p8y:A, 3p8y:B, 3reu:A, 3reu:B, 3rex:A, 3rex:B, 3rl6:A, 3rl6:B
39 7u0r:B 278 116 0.0678 0.1187 0.2845 0.21 8c49:A, 8c49:B, 8dqg:D, 8dqg:A, 8dqh:D, 8dqh:A, 8dqi:D, 8dqi:A, 8dqj:D, 7u0r:A
40 6hxi:C 410 81 0.0534 0.0634 0.3210 0.29 6hxi:A, 6znw:A
41 8ci0:AAA 666 195 0.0903 0.0661 0.2256 1.1 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
42 6ha8:V 541 97 0.0452 0.0407 0.2268 1.3
43 7by6:A 299 26 0.0267 0.0435 0.5000 1.8
44 3mbo:E 375 84 0.0452 0.0587 0.2619 2.2 3mbo:A, 3mbo:C, 3mbo:H
45 7dpi:C 292 26 0.0267 0.0445 0.5000 2.3 7dpi:A
46 3l4g:C 508 55 0.0370 0.0354 0.3273 3.1 3l4g:A, 3l4g:E, 3l4g:G, 3l4g:I, 3l4g:K, 3l4g:M, 3l4g:O
47 2du3:A 534 68 0.0349 0.0318 0.2500 3.8 2du5:A, 2du6:A
48 2du4:A 466 68 0.0349 0.0365 0.2500 3.8 2du3:B, 2du5:B, 2du6:B
49 5mgu:A 407 44 0.0308 0.0369 0.3409 4.0 3cmq:A, 3hfv:A, 5mgh:A, 5mgw:A, 8p8x:A, 3teg:A, 3tup:A
50 6z1p:BS 433 130 0.0657 0.0739 0.2462 4.9
51 5ve8:B 1030 73 0.0370 0.0175 0.2466 6.0 5ve8:A, 5w0v:A, 5w0v:B
52 5hb3:C 709 27 0.0287 0.0197 0.5185 8.2 5hb3:A, 7tbi:D1, 7tbi:D2, 7tbi:D3, 7tbi:D4
53 3m49:A 665 84 0.0472 0.0346 0.2738 9.3 3hyl:A, 3hyl:B, 3m49:B
54 4p85:A 390 55 0.0370 0.0462 0.3273 9.8 4p85:B, 4p87:A, 4p87:B, 5zwq:A, 5zwq:B, 5zwr:B, 5zwr:A
55 8dqj:A 251 105 0.0595 0.1155 0.2762 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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