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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PQEVSDIKKFIEICRRKDASSARIKKNPKTQQIKFKVRCQRFLYTLVLKDSDKAEKLKQSLPPNLQIKDVPKRNKRKSSA

The query sequence (length=80) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7z3n:Lk 80 80 1.0000 1.0000 1.0000 5.15e-52 8i9x:Lk, 8i9y:Lk, 8i9z:Lk, 8ia0:Lk, 7olc:Lk, 7old:Lk, 8onz:Lk, 8oo0:Lk, 8pv1:Lk, 8pv2:Lk, 8pv3:Lk, 8pv4:Lk, 8pv5:Lk, 8pv6:Lk, 8pv7:Lk, 8pv8:Lk, 8pvk:Lk, 8pvl:Lk, 7z3o:Lk
2 7r81:m1 73 73 0.7625 0.8356 0.8356 1.73e-39
3 8esq:k 70 70 0.5375 0.6143 0.6143 7.32e-27 8esr:k, 8etc:k, 8etg:k, 8eug:k, 8eui:k
4 4v6w:Ck 70 70 0.4875 0.5571 0.5571 3.48e-23 6xu6:Ck, 6xu7:Ck, 6xu8:Ck
5 9bh5:Ck 69 70 0.5125 0.5942 0.5857 5.92e-23 9cai:Ck
6 7a01:p2 69 70 0.5000 0.5797 0.5714 2.52e-22 8a3d:e, 5aj0:Ak, 8b5l:k, 8b6c:k, 9bdl:AL38, 9bdn:AL38, 9bdp:AL38, 8bf9:k, 7bhp:Lk, 8bhf:X1, 8bpo:j2, 8btk:Bk, 7cpu:Lk, 7cpv:Lk, 4d5y:k, 4d67:k, 6d90:k, 6d9j:k, 9f1b:Bk, 9f1c:Bk, 9f1d:Bk, 7f5s:Lk, 8fkz:LY, 8fl2:LY, 8fl3:LY, 8fl4:LY, 8fl6:LY, 8fl7:LY, 8fl9:LY, 8fla:LY, 8flb:LY, 8flc:LY, 8fld:LY, 8fle:LY, 8flf:LY, 9fpz:Lk, 9fq0:Lk, 6frk:k, 6ftg:k, 6fti:k, 6ftj:k, 8g5y:Lk, 8g5z:Lk, 8g60:Lk, 8g61:Lk, 8g6j:Lk, 8glp:Lk, 6gz3:Ak, 6gz4:Ak, 6gz5:Ak, 6hcf:k3, 6hcj:k3, 6hcm:k3, 6hcq:k3, 8idt:O, 8idy:O, 8ie3:O, 8ifd:2e, 8ife:2e, 8ine:O, 8inf:O, 8ink:O, 6ip5:2e, 6ip6:2e, 6ip8:2e, 8ipd:O, 8ipx:O, 8ipy:O, 8ir1:O, 8ir3:O, 3j7o:k, 3j7p:k, 3j7q:k, 3j7r:k, 3j92:k, 3jag:k, 3jah:k, 3jai:k, 3jaj:k, 3jan:k, 8jdj:p, 8jdk:p, 8jdl:p, 8jdm:p, 8k2c:Lk, 5lks:Lk, 6lqm:O, 6lsr:O, 6lss:O, 7ls1:e2, 7ls2:e2, 6lu8:O, 5lzs:k, 5lzt:k, 5lzu:k, 5lzv:k, 5lzw:k, 5lzx:k, 5lzy:k, 5lzz:k, 7mdz:k, 6mtb:k, 6mtc:k, 6mtd:k, 6mte:k, 7nfx:k, 7nwg:k3, 7nwh:k, 7nwi:k, 7o7y:Bk, 7o7z:Bk, 7o80:Bk, 7o81:Bk, 7obr:k, 8ohd:Lk, 8oj0:Lk, 8oj5:Lk, 8oj8:Lk, 6ole:l, 6olf:l, 6olg:Ak, 6oli:l, 6olz:Ak, 6om0:l, 6om7:l, 8ony:Lk, 7oya:k1, 7oyb:k1, 7oyc:k1, 7oyd:k, 8p2k:Bk, 6p5i:Ak, 6p5j:Ak, 6p5k:Ak, 6p5n:Ak, 8q7z:Bk, 8q87:Bk, 8qfd:k, 7qgg:l, 8qoi:Lk, 7qvp:Lk, 7qvp:Mk, 7qwq:k, 7qwr:k, 7qws:k, 6qzp:Lk, 6r5q:k, 6r6g:k, 6r6p:k, 6r7q:k, 8rjb:k, 8rjc:k, 8rjd:k, 8scb:k, 6sgc:k2, 6swa:i, 6sxo:Lk, 5t2c:e, 6t59:k3, 7tm3:k, 7toq:AL38, 7tor:AL38, 7tut:k, 7ucj:k, 7uck:k, 4ug0:Lk, 4ujc:Bk, 4ujd:Ak, 4uje:Ck, 4v6x:Ck, 6w6l:l, 6xa1:Lk, 7xnx:Lk, 7xny:Lk, 8xsx:Lk, 8xsy:Lk, 8xsz:Lk, 6y0g:Lk, 8y0w:Lk, 8y0x:Lk, 6y2l:Lk, 6y57:Lk, 6y6x:Lk, 8yoo:Lk, 8yop:Lk, 6z6l:Lk, 6z6m:Lk, 6z6n:Lk, 7zjw:Ln, 7zjx:Ln, 6zm7:Lk, 6zme:Lk, 6zmi:Lk, 6zmo:Lk, 6zvk:p2
7 4v3p:Ln 69 70 0.4625 0.5362 0.5286 3.09e-20 8ip8:NB, 8ipa:NB, 8ipb:NB, 8jiv:Ck, 4v7e:Ck
8 8azw:W 68 70 0.4500 0.5294 0.5143 3.32e-20 8b2l:W3, 7qiw:m, 7qiz:m
9 6zj3:Lz 70 65 0.4500 0.5143 0.5538 7.87e-20
10 8c3a:AL 77 77 0.4625 0.4805 0.4805 1.02e-18 8c3a:CF, 8cq7:AL, 8cq7:CF, 8cqw:AL, 8cqw:CF, 8cre:AL, 8cre:CF, 8oeq:AL, 8oeq:CF, 7pzy:AL, 7q08:AL, 7q0f:AL, 7q0p:AL, 7q0r:AL, 8q5i:AL
11 8rxh:Lk 78 80 0.4375 0.4487 0.4375 1.14e-18 8a3w:k, 8a98:k, 6az3:k, 3jcs:k, 8ovj:k, 8rxx:Lk, 5t2a:n
12 5it7:kk 76 73 0.4250 0.4474 0.4658 2.68e-18 6uz7:Bk
13 4v8m:Bp 81 66 0.4000 0.3951 0.4848 6.20e-18 8ova:Bp, 8ove:Bp, 5t5h:p
14 5xxb:j 72 70 0.3875 0.4306 0.4429 3.77e-17
15 4v6i:Bn 78 73 0.4375 0.4487 0.4795 6.03e-17 8aaf:X, 8agt:X, 8agu:X, 8agv:X, 8agw:X, 8agx:X, 8agz:X, 5apn:k, 5apo:k, 7azy:j, 7b7d:Lg, 8bip:Lk, 8bjq:Lk, 8bn3:O8, 8bqd:AI, 8bqx:AI, 7bt6:k, 7btb:k, 6cb1:k, 8ccs:W, 8cdl:W, 8cdr:W, 8ceh:W, 8cf5:W, 8cg8:W, 8cgn:W, 8civ:W, 8cku:W, 8cmj:W, 5dat:O8, 5dat:o8, 5dc3:O8, 5dc3:o8, 5dge:O8, 5dge:o8, 5dgf:O8, 5dgf:o8, 5dgv:O8, 5dgv:o8, 6elz:k, 8eub:Ak, 8evp:Ak, 8evq:Ak, 8evr:Ak, 8evs:Ak, 8evt:Ak, 8ewb:Ak, 8ewc:Ak, 5fci:O8, 5fci:o8, 5fcj:O8, 5fcj:o8, 6ft6:k, 5gak:m, 6gq1:k, 6gqb:k, 6gqv:k, 5h4p:k, 6hd7:m, 8hfr:kr, 6hhq:AL, 6hhq:DM, 5i4l:O8, 5i4l:o8, 6i7o:AI, 6i7o:XI, 3j6x:78, 3j6y:78, 3j77:88, 3j78:88, 3jct:k, 5jcs:k, 5juo:PA, 5jup:PA, 5jus:PA, 5jut:PA, 5juu:PA, 8k2d:Lk, 8k82:Lk, 5lyb:O8, 5lyb:o8, 5m1j:k5, 6m62:k, 5mc6:AI, 5mei:AL, 5mei:DM, 7mpi:Ak, 7mpj:Ak, 6n8j:k, 6n8k:k, 6n8l:k, 6n8m:x, 6n8n:x, 6n8o:x, 7n8b:Ak, 7nac:k, 7nad:k, 5ndg:O8, 5ndg:o8, 5ndv:O8, 5ndv:o8, 5ndw:O8, 5ndw:o8, 7nrc:Lm, 7nrd:Lm, 5obm:O8, 5obm:o8, 7of1:k, 7oh3:k, 7ohq:k, 7ohr:k, 6oig:k, 5on6:AL, 5on6:DM, 7osa:eL38, 7osm:eL38, 8p8m:RM, 8p8n:RM, 8p8u:RM, 8pfr:RM, 6q8y:AI, 6qik:j, 6qt0:j, 6qtz:j, 7r72:k, 7r7a:k, 6r84:m, 6r86:m, 6r87:m, 6ri5:j, 7rr5:Lk, 6rzz:j, 6s05:j, 6s47:Am, 6snt:af, 6sv4:AI, 6sv4:XI, 6sv4:zI, 6t4q:Lk, 5t62:x, 5t6r:x, 6t7i:Lk, 6t7t:Lk, 6t83:kb, 6t83:V, 5tbw:AL, 5tbw:DM, 6tb3:AI, 5tga:O8, 5tga:o8, 5tgm:O8, 5tgm:o8, 6tnu:AI, 7too:AL38, 7top:AL38, 7u0h:k, 4u3m:O8, 4u3m:o8, 4u3n:O8, 4u3n:o8, 4u3u:O8, 4u3u:o8, 4u4n:O8, 4u4n:o8, 4u4o:O8, 4u4o:o8, 4u4q:O8, 4u4q:o8, 4u4r:O8, 4u4r:o8, 4u4u:O8, 4u4u:o8, 4u4y:O8, 4u4y:o8, 4u4z:O8, 4u4z:o8, 4u50:O8, 4u50:o8, 4u51:O8, 4u51:o8, 4u52:O8, 4u52:o8, 4u53:O8, 4u53:o8, 4u55:O8, 4u55:o8, 4u56:O8, 4u56:o8, 4u6f:O8, 4u6f:o8, 7ug6:k, 7uoo:k, 7uqb:k, 7uqz:k, 7v08:k, 4v88:Bk, 4v88:Dk, 4v8t:k, 4v8y:Bk, 4v8z:Bk, 8v87:k, 4v91:k, 6woo:k, 6xiq:k, 6xir:k, 8y0u:Lk, 6ylg:k, 6ylh:k, 6ylx:k, 6yly:k, 7z34:k, 6z6j:Lk, 6z6k:Lk, 7zpq:Bj, 7zrs:Bj, 7zs5:Bl, 7zuw:Bj, 7zux:Ej, 7zw0:Ln
16 3j79:d 72 67 0.3500 0.3889 0.4179 8.14e-13 3jbn:Ad, 3jbo:Ad, 3jbp:Ad, 8tpu:Ad, 5umd:d
17 7ohv:k 63 67 0.4250 0.5397 0.5075 1.59e-10
18 4v8p:AP 66 62 0.2500 0.3030 0.3226 1.54e-05 4v8p:DP, 4v8p:FP, 4v8p:HP
19 5xy3:k 68 67 0.2750 0.3235 0.3284 2.10e-05
20 3goe:A 80 31 0.1750 0.1750 0.4516 0.82
21 8fru:k 76 39 0.1250 0.1316 0.2564 1.1 8br8:Ll, 8brm:Ll, 8bsi:Ll, 8bsj:Ll, 8btd:Ll, 8btr:Ll, 7pwg:k, 7pwo:k2
22 5w81:A 1173 47 0.1750 0.0119 0.2979 4.8
23 3mu3:A 140 48 0.1875 0.1071 0.3125 5.0 3mu3:B
24 7r9g:A 386 30 0.1000 0.0207 0.2667 6.2 7r9f:A
25 7m6a:A 4306 16 0.1125 0.0021 0.5625 6.8 7m6a:G, 7m6a:B, 7m6a:I, 7m6l:A, 7m6l:G, 7m6l:B, 7m6l:I
26 8vk4:D 4379 16 0.1125 0.0021 0.5625 7.0 8vjj:A, 8vjj:D, 8vjj:B, 8vjj:C, 8vjk:A, 8vjk:B, 8vjk:C, 8vjk:D, 8vk3:A, 8vk3:D, 8vk3:B, 8vk3:C, 8vk4:A, 8vk4:B, 8vk4:C
27 7tzc:A 4404 16 0.1125 0.0020 0.5625 7.3 3rqr:A, 8sen:A, 8sen:B, 8sen:C, 8sen:D, 8seo:A, 8seo:B, 8seo:C, 8seo:D, 8sep:A, 8sep:B, 8sep:C, 8sep:D, 8seq:A, 8seq:B, 8seq:C, 8seq:D, 8ser:A, 8ser:B, 8ser:C, 8ser:D, 8ses:A, 8ses:B, 8ses:C, 8ses:D, 8set:A, 8set:B, 8set:C, 8set:D, 7tzc:B, 7tzc:G, 7tzc:I
28 7pu7:A 1070 18 0.0875 0.0065 0.3889 8.6 5lew:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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