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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSYSAVNQGHCHPKIVNALKSQVDKLTLTSRAFY
NNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDG
FGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWL
AVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGIIL
RNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKTI
LSF

The query sequence (length=403) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2byj:A 404 403 0.9975 0.9950 0.9975 0.0 2byj:B, 2byj:C, 2byl:A, 2byl:B, 2byl:C, 2can:A, 2can:B, 2can:C, 8ez1:A, 8ez1:B, 8ez1:C, 1gbn:A, 1gbn:B, 1gbn:C, 6hx7:A, 6hx7:B, 6hx7:C, 7jx9:A, 7jx9:B, 7jx9:C, 7lk0:A, 7lk0:B, 7lk0:C, 7lk1:A, 7lk1:B, 7lk1:C, 7lnm:B, 7lnm:C, 7lnm:E, 7lnm:F, 7lnm:I, 7lnm:J, 7lom:A, 7lom:B, 7lom:C, 7lon:B, 7lon:A, 7lon:C, 1oat:A, 1oat:B, 1oat:C, 2oat:A, 2oat:B, 2oat:C, 6oia:A, 6oia:B, 6oia:C, 7t9z:A, 7t9z:B, 7t9z:C, 7ta0:A, 7ta0:B, 7ta0:C, 7ta1:A, 7ta1:B, 7ta1:C, 7ta1:D, 7ta1:E, 7ta1:F, 7ted:A, 7ted:B, 7ted:C, 7ted:I, 7ted:D, 7ted:E, 7ted:F, 7ted:G, 7ted:H, 7tev:A, 7tev:B, 7tev:C, 7tfp:A, 7tfp:B, 7tfp:C, 6v8c:A, 6v8c:B, 6v8c:C, 6v8d:A, 6v8d:B, 6v8d:C, 8v9m:A, 8v9m:B, 8v9m:C, 5vwo:A, 5vwo:B, 5vwo:C
2 5eqc:A 426 405 0.5161 0.4883 0.5136 2.19e-147 5dj9:A, 5dj9:B, 5e3k:A, 5e3k:B, 5e5i:A, 5e5i:B, 5eqc:B, 4nog:A, 4nog:B, 4zlv:A, 4zlv:B, 4zwm:A, 4zwm:B
3 2eh6:A 375 389 0.3499 0.3760 0.3625 9.53e-78 2eh6:B
4 4jev:B 402 384 0.3424 0.3433 0.3594 2.62e-74 4jev:A, 4jew:A, 4jew:B, 4jex:A, 4jex:B, 4jey:A, 4jey:B, 4jez:A, 4jez:B, 4jf1:A, 4jf1:B, 2pb0:A, 2pb0:B, 2pb2:A
5 1vef:A 387 394 0.3400 0.3540 0.3477 7.39e-74 1vef:B, 1wkg:A, 1wkg:B, 1wkh:A, 1wkh:B
6 2ord:A 393 389 0.3375 0.3461 0.3496 8.67e-72 2e54:A, 2ord:B
7 8ht4:B 390 394 0.3424 0.3538 0.3503 1.64e-68 8ht4:A
8 3nx3:A 388 385 0.3102 0.3222 0.3247 9.12e-66
9 7nn4:A 391 390 0.3449 0.3555 0.3564 1.14e-64 7nn4:B, 7nn4:C, 7nn4:D, 7nnc:C
10 4adb:B 401 379 0.3275 0.3292 0.3483 4.28e-64 4adb:A, 4adb:C, 4adb:D, 4adc:A, 4adc:B, 4adc:C, 4adc:D, 4add:A, 4add:B, 4add:C, 4add:D
11 8cpl:C 499 384 0.3176 0.2565 0.3333 1.57e-63 8cpl:A, 8cpl:B, 8cpl:D, 1lp1:B, 4uox:A, 4uox:B, 4uox:C, 4uox:D, 4uoy:A, 4uoy:B, 4uoy:C, 4uoy:D
12 1sf2:A 425 410 0.3176 0.3012 0.3122 1.28e-58 1sf2:B, 1sf2:C, 1sf2:D, 1sff:A, 1sff:B, 1sff:C, 1sff:D, 1szk:A, 1szk:B, 1szk:C, 1szk:D, 1szs:A, 1szs:B, 1szs:C, 1szs:D, 1szu:A, 1szu:B, 1szu:C, 1szu:D
13 4ppm:A 464 440 0.3226 0.2802 0.2955 6.78e-53 4ppm:B
14 3du4:A 448 427 0.3325 0.2991 0.3138 2.37e-52 3du4:B
15 6io1:B 448 427 0.3275 0.2946 0.3091 1.28e-49 6io1:A
16 6fyq:A 443 411 0.2953 0.2686 0.2895 1.58e-49
17 6wnn:A 420 414 0.3275 0.3143 0.3188 6.45e-49 3dod:A, 3dod:B, 6wnn:B
18 2eo5:A 412 413 0.3052 0.2985 0.2978 7.12e-49
19 6j2v:A 440 428 0.3400 0.3114 0.3201 1.55e-48 6j2v:B, 6j2v:C, 6j2v:D
20 3q8n:C 439 411 0.3300 0.3030 0.3236 1.68e-48 3q8n:A, 3q8n:B, 3q8n:D
21 4ysn:C 448 433 0.3127 0.2812 0.2910 3.37e-47 5ll3:A, 5ll3:B, 5ll3:C, 5ll3:D, 5wya:A, 5wya:B, 5wya:C, 5wya:D, 5wyf:A, 5wyf:B, 5wyf:C, 5wyf:D, 4ysn:A, 4ysn:B, 4ysn:D
22 6s54:A 453 444 0.3201 0.2848 0.2905 8.33e-47 6s54:B, 6s54:C, 6s54:D
23 6zhk:A 438 396 0.3151 0.2900 0.3207 1.65e-46 6zhk:B
24 7vno:A 452 441 0.3300 0.2942 0.3016 2.19e-45 7vno:B, 7vnt:A, 7vnt:B, 7vo1:A, 7vo1:B
25 5lh9:D 449 417 0.3052 0.2739 0.2950 6.11e-43 5lh9:A, 5lh9:B, 5lh9:C, 5lha:A, 5lha:B, 5lha:C, 5lha:D
26 5kr6:B 460 456 0.3251 0.2848 0.2873 1.39e-42 5kr6:A
27 1d7r:A 431 419 0.3127 0.2923 0.3007 1.84e-41 1d7s:A, 1d7u:A, 1d7v:A, 1dgd:A, 1dge:A, 1dka:A, 2dkb:A, 1m0n:A, 1m0o:A, 1m0p:A, 1m0q:A, 1z3z:A, 1zc9:A, 1zob:A, 1zod:A
28 4uhm:A 435 421 0.2903 0.2690 0.2779 3.89e-41 4uhn:A, 4uho:A
29 6erk:A 420 426 0.3077 0.2952 0.2911 4.11e-41 6erk:B
30 5kr3:A 458 458 0.3102 0.2729 0.2729 9.64e-40 5kr3:B, 5kr4:A, 5kr4:B, 5kr5:A, 5kr5:B
31 4atq:F 444 439 0.3226 0.2928 0.2961 1.38e-39 4atp:A, 4atp:B, 4atp:C, 4atp:D, 4atp:E, 4atp:F, 4atp:G, 4atp:H, 4atp:I, 4atp:J, 4atp:K, 4atp:L, 4atq:A, 4atq:B, 4atq:C, 4atq:D, 4atq:E, 4atq:G, 4atq:H, 4atq:I, 4atq:J, 4atq:K, 4atq:L
32 6g4d:B 453 442 0.2878 0.2561 0.2624 3.02e-39 7b4i:AAA, 7b4i:BBB, 7b4j:A, 7b4j:B, 6g4d:A, 6g4e:A, 6g4e:B, 6g4f:A, 6g4f:B, 6tb0:A, 6tb0:B, 6tb1:A, 6tb1:B
33 5ghg:B 433 435 0.2878 0.2679 0.2667 2.60e-38 5ghf:A
34 6jix:A 447 445 0.3052 0.2752 0.2764 3.85e-38 6jix:B, 6jix:D, 6jix:C
35 6gwi:B 450 439 0.3027 0.2711 0.2779 5.04e-38 6gwi:A
36 4b98:A 441 441 0.2953 0.2698 0.2698 1.06e-37 4b98:B, 4b98:C, 4b98:D, 4b9b:A, 4b9b:B, 4b9b:C, 4b9b:D, 4b9b:E, 4b9b:F, 4b9b:G, 4b9b:H, 4bq0:A, 4bq0:B, 4bq0:C, 4bq0:D
37 7ypn:D 455 429 0.3002 0.2659 0.2821 1.10e-36 7ypm:A, 7ypm:B, 7ypm:D, 7ypm:C, 7ypn:B
38 5kqu:C 459 457 0.3102 0.2723 0.2735 2.48e-36 5kqt:A, 5kqu:A, 5kqu:D, 5kqu:B, 5kqu:E, 5kqu:F
39 5ti8:B 384 391 0.2705 0.2839 0.2788 4.11e-36
40 7qx0:B 443 436 0.2829 0.2573 0.2615 4.40e-35 7qx0:A, 7qx0:C, 7qx0:D, 7qx3:B, 7qx3:C, 7qx3:A, 7qx3:D
41 6rl5:G 422 410 0.2804 0.2678 0.2756 1.72e-34 6rl5:A, 6rl5:B, 6rl5:C, 6rl5:D, 6rl5:E, 6rl5:F, 6rl5:H
42 7qzj:A 422 429 0.3226 0.3081 0.3030 2.36e-34 7qzj:B
43 2cfb:A 360 299 0.2308 0.2583 0.3110 2.70e-34
44 6tor:B 404 419 0.2779 0.2772 0.2673 4.44e-34 6tor:A
45 1dty:A 429 436 0.3127 0.2937 0.2890 5.92e-34 1dty:B, 6ed7:A, 6ed7:B, 6ed7:C, 6ed7:D, 6ed7:E, 6ed7:F, 6ed7:G, 6ed7:H, 1mgv:A, 1mgv:B, 1mly:A, 1mly:B, 1mlz:A, 1mlz:B, 1qj3:A, 1qj3:B, 1qj5:A, 1qj5:B, 1s07:A, 1s07:B
46 3gju:A 458 449 0.3027 0.2664 0.2717 1.17e-33
47 4a6t:C 455 442 0.2854 0.2527 0.2602 2.18e-33 4a6r:A, 4a6r:B, 4a6t:A, 4a6t:B, 4a6t:D, 4a72:C, 4a72:D, 4ah3:A, 4ah3:B, 4ah3:D, 4ah3:C, 4ba5:A, 4ba5:B, 7q9x:AAA, 7q9x:BBB, 7q9x:CCC, 7q9x:DDD, 7q9z:AAA, 7q9z:BBB, 6s4g:A, 6s4g:B, 6s4g:C, 6s4g:D, 6snu:A, 6snu:B, 6snu:C, 6snu:D
48 8wqj:A 472 442 0.2829 0.2415 0.2579 6.48e-33 8wqj:B
49 5g4i:A 423 420 0.2754 0.2624 0.2643 8.14e-33 5g4i:B, 5g4j:A, 5g4j:B
50 4wyd:A 430 376 0.2705 0.2535 0.2899 1.66e-32 3bv0:A, 3bv0:B, 4cxq:A, 4cxq:B, 4cxr:A, 4cxr:B, 6ge8:A, 6ge8:B, 5kgs:A, 5kgs:B, 5kgt:A, 5kgt:B, 3lv2:A, 3lv2:B, 4mqp:A, 4mqp:B, 4mqq:A, 4mqq:B, 4mqr:A, 4mqr:B, 5te2:B, 5te2:A, 3tft:A, 3tft:B, 3tfu:A, 3tfu:B, 4w1v:A, 4w1v:B, 4w1w:A, 4w1w:B, 4w1x:A, 4w1x:B, 4wya:A, 4wya:B, 4wya:C, 4wya:D, 4wyc:A, 4wyc:B, 4wyd:B, 4wye:A, 4wye:B, 4wyf:A, 4wyf:B, 4wyg:A, 4wyg:B, 4xew:A, 4xew:B, 4xjl:A, 4xjl:B, 4xjm:A, 4xjm:B, 4xjo:A, 4xjo:B, 4xjp:A, 4xjp:B
51 3a8u:X 441 425 0.3102 0.2834 0.2941 2.59e-32
52 3fq7:A 427 326 0.2407 0.2272 0.2975 1.81e-31 3fq7:B, 3fq8:A, 3fq8:B, 3fqa:A, 3fqa:B, 2gsa:A, 2gsa:B, 3gsb:A, 3gsb:B, 4gsa:A, 4gsa:B, 2hoz:A, 2hoz:B, 2hp1:A, 2hp2:A, 2hp2:B, 3usf:A
53 5m4b:A 439 409 0.2829 0.2597 0.2787 1.81e-31 5m46:A, 5m49:A, 5m4d:A
54 3usf:B 402 321 0.2308 0.2313 0.2897 2.63e-31 2hp1:B
55 6w80:A 430 307 0.2333 0.2186 0.3062 4.48e-31
56 3fcr:A 458 427 0.2878 0.2533 0.2717 5.25e-31
57 4e3q:A 452 422 0.2730 0.2434 0.2607 7.70e-31 4e3q:B, 4e3q:C, 4e3q:D, 4grx:C
58 2cin:A 435 417 0.2928 0.2713 0.2830 9.57e-30 2cjd:A, 2cjg:A, 2cjh:A, 2jje:A, 2jjg:A, 2jjh:A
59 5hdm:A 428 315 0.2357 0.2220 0.3016 7.99e-29 5hdm:B
60 3bs8:A 430 318 0.2407 0.2256 0.3050 1.31e-28
61 2e7u:A 424 296 0.2308 0.2193 0.3142 1.77e-28
62 2zsm:A 425 298 0.2208 0.2094 0.2987 2.36e-28 2epj:A, 2zsl:A, 2zsm:B, 2zsm:C
63 3k28:A 423 302 0.2357 0.2246 0.3146 2.67e-28 3k28:B, 3k28:C, 3k28:D
64 6gio:C 436 404 0.2754 0.2546 0.2748 2.21e-27 6gio:D, 6gio:A, 6gio:B
65 4ao9:A 433 364 0.2481 0.2309 0.2747 5.84e-26 4ao9:B, 4aoa:A, 4aoa:B
66 5g09:D 473 382 0.2531 0.2156 0.2670 7.92e-26 5g09:A, 5g09:B, 5g09:C, 5g0a:A, 5g0a:B, 5g0a:C, 5g0a:D, 5g2p:A, 5g2p:B, 5g2p:C, 5g2p:D, 5g2q:A, 5g2q:B, 5g2q:C, 5g2q:D, 5g2q:E, 5g2q:F, 5g2q:G, 5g2q:H, 5g2q:I, 5g2q:J, 5g2q:K, 5g2q:L
67 5i92:F 420 291 0.2109 0.2024 0.2921 1.36e-25
68 3i5t:A 444 419 0.2506 0.2275 0.2411 1.53e-25 3i5t:B
69 3dxv:B 434 410 0.2506 0.2327 0.2463 1.82e-24 3dxv:A, 3dxw:A, 3dxw:B, 2zuk:A, 2zuk:B
70 4zm4:D 387 324 0.2109 0.2196 0.2623 2.87e-18
71 4zm4:B 425 290 0.1960 0.1859 0.2724 1.81e-17 4zm3:A, 4zm3:B, 4zm3:C, 4zm3:D, 4zm4:A, 4zm4:C, 4zm4:E, 4zm4:F
72 6k8h:B 441 306 0.1911 0.1746 0.2516 2.01e-17 6k8h:A
73 6ssd:A 424 302 0.1985 0.1887 0.2649 2.54e-17 6sse:A, 6sse:B, 6ssf:A, 6ssf:B, 6ssg:A, 6ssg:B
74 6kfu:A 527 311 0.1985 0.1518 0.2572 1.24e-16 6kfm:A, 6kfm:B, 6kfr:A, 6kfr:B
75 5ykt:A 453 313 0.1836 0.1634 0.2364 2.03e-15 5ykt:B
76 5dds:A 514 226 0.1489 0.1167 0.2655 1.03e-14 5dds:B, 5dds:C, 5dds:D, 5ddu:A, 5ddu:B, 5ddu:C, 5ddu:D, 5ddw:A, 5ddw:B, 5ddw:C, 5ddw:D, 6jc7:A, 6jc7:B, 6jc7:C, 6jc7:D, 6jc8:A, 6jc8:B, 6jc8:C, 6jc8:D, 6jc9:A, 6jc9:B, 6jc9:C, 6jc9:D, 8jt3:A, 8jt3:B, 8jt3:C, 8jt3:D
77 5dds:A 514 99 0.0645 0.0506 0.2626 0.49 5dds:B, 5dds:C, 5dds:D, 5ddu:A, 5ddu:B, 5ddu:C, 5ddu:D, 5ddw:A, 5ddw:B, 5ddw:C, 5ddw:D, 6jc7:A, 6jc7:B, 6jc7:C, 6jc7:D, 6jc8:A, 6jc8:B, 6jc8:C, 6jc8:D, 6jc9:A, 6jc9:B, 6jc9:C, 6jc9:D, 8jt3:A, 8jt3:B, 8jt3:C, 8jt3:D
78 4y0h:D 463 440 0.2308 0.2009 0.2114 1.74e-14 6b6g:A, 6b6g:B, 6b6g:C, 6b6g:D, 1ohv:A, 1ohv:B, 1ohv:C, 1ohv:D, 1ohw:A, 1ohw:B, 1ohw:C, 1ohw:D, 1ohy:A, 1ohy:B, 1ohy:C, 1ohy:D, 4y0d:A, 4y0d:B, 4y0d:C, 4y0d:D, 4y0h:A, 4y0h:B, 4y0h:C, 4y0i:A, 4y0i:B, 4y0i:C, 4y0i:D, 4zsw:A, 4zsw:B, 4zsw:C, 4zsw:D, 4zsy:A, 4zsy:B, 4zsy:C, 4zsy:D
79 2yku:A 433 317 0.2060 0.1917 0.2618 7.37e-14 4ao4:A, 4ao4:B, 4ao4:C, 2yku:B, 2yku:C, 2ykv:A, 2ykv:B, 2ykv:C, 2ykx:A, 2ykx:B, 2ykx:C, 2yky:A, 2yky:B, 2yky:C
80 4a0g:A 769 201 0.1315 0.0689 0.2637 1.13e-13 4a0f:B, 4a0g:B, 4a0h:A, 4a0h:B, 4a0r:A, 4a0r:B
81 4a0f:A 746 312 0.1886 0.1019 0.2436 3.13e-13
82 4a0g:D 709 299 0.1787 0.1016 0.2408 9.36e-13
83 4a0g:C 681 191 0.1216 0.0720 0.2565 4.82e-12
84 7lld:A 446 317 0.2035 0.1839 0.2587 7.86e-10 7lld:B, 7lle:A, 7lle:B
85 6hbv:A 414 392 0.1985 0.1932 0.2041 6.32e-07 6hbs:A, 6hbs:B, 6hbv:B
86 7lm0:A 449 346 0.2109 0.1893 0.2457 4.37e-06 7lm0:B
87 9aue:A 415 261 0.1563 0.1518 0.2414 1.21e-04 9au3:A, 9b0c:A
88 6cbk:D 422 126 0.1017 0.0972 0.3254 4.28e-04 6cbk:A, 6cbk:B, 6cbk:C, 6cbl:A, 6cbl:B, 6cbl:C, 6cbl:D, 6cbl:E, 6cbl:F, 6cbl:G, 6cbl:H, 6cbm:A, 6cbm:B, 6cbn:A, 6cbn:B
89 3l8a:B 385 63 0.0521 0.0545 0.3333 0.022 3l8a:A
90 7qug:A 397 256 0.1340 0.1360 0.2109 0.21
91 6cbo:C 411 267 0.1489 0.1460 0.2247 0.24 6cbo:A, 6cbo:B, 6cbo:D, 5z83:A, 5z83:B, 5z8a:A, 5z8a:B, 5z8k:A, 5z8k:B
92 7zi4:G 682 130 0.0769 0.0455 0.2385 0.58
93 3b1c:A 387 52 0.0397 0.0413 0.3077 1.5 3b1c:B, 3b1c:C, 3b1c:D, 3b1d:A, 3b1d:B, 3b1d:C, 3b1d:D, 3b1e:A, 3b1e:B, 3b1e:C, 3b1e:D
94 6qp3:A 387 64 0.0496 0.0517 0.3125 1.6 6qp3:B, 6qp3:C, 6qp3:D
95 1xre:A 201 68 0.0620 0.1244 0.3676 2.7 1xre:B
96 3lvm:B 394 255 0.1365 0.1396 0.2157 3.2 3lvj:A, 3lvj:B, 3lvk:A, 3lvl:B, 3lvm:A, 1p3w:B, 1p3w:A
97 7vob:C 327 45 0.0347 0.0428 0.3111 6.2 7voc:C
98 3t6q:C 139 48 0.0347 0.1007 0.2917 6.2 3m7o:A, 3m7o:D, 3t6q:D
99 1p17:B 204 132 0.0794 0.1569 0.2424 8.1 1i0i:A, 1i0i:B, 1i0l:A, 1i0l:B, 1i13:A, 1i13:B, 1i14:A, 1i14:B, 1p17:A, 1p17:C, 1p17:D, 1p18:A, 1p18:B, 1p19:A, 1p19:B, 1p19:C, 1p19:D, 1tc1:A, 1tc1:B, 1tc2:A, 1tc2:B
100 7dk8:A 558 43 0.0372 0.0269 0.3488 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218