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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PPQKIEIFKSLDNWAEENILVHLKPVEKCWQPQDFLPDPASDGFDEQVRELRERAKEIPDDYFVVLVGDMIKEEALPTYQ
TMLNTLDGVRDETGASPTSWAIWTRAWTAEENRHGDLLNKYLYLSGRVDMRQIEKTIQYLIGSGMDPRTENSPYLGFIYT
SFQERATFIEHGNTARQAKEHGDIKLAQICGTIAADEKRHETAYTKIVEKLFEIDPDGTVLAFADMMRKKISMPAHLMYD
GRDDNLFDHFSAVAQRLGVYTAKDYADILEFLVGRWKVDKLTGLSAEGQKAQDYVCRLPPRIRRLEERAPTMPFSWIFDR
QVKL

The query sequence (length=324) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xz1:A 353 331 0.9938 0.9122 0.9728 0.0 1afr:A, 1afr:B, 1afr:C, 1afr:D, 1afr:E, 1afr:F, 2j2f:A, 2j2f:B, 2j2f:C, 2j2f:D, 2j2f:E, 2j2f:F, 1oq4:A, 1oq4:B, 1oq4:C, 1oq4:D, 1oq4:E, 1oq4:F, 1oq9:A, 1oqb:A, 1oqb:B, 1oqb:C, 1oqb:D, 1oqb:E, 1oqb:F, 4v0j:A, 4v0j:B, 4v0j:C, 4v0j:D, 4v0j:E, 4v0j:F, 2xz0:A, 2xz0:B, 2xz0:C, 2xz1:B
2 2uw1:B 338 331 0.8056 0.7722 0.7885 0.0 2uw1:A
3 7t63:B 334 328 0.6944 0.6737 0.6860 1.06e-174 7t63:A
4 7pp7:A 311 326 0.6574 0.6849 0.6534 5.60e-159
5 1za0:A 242 120 0.1111 0.1488 0.3000 9.87e-06
6 5szo:B 414 230 0.1574 0.1232 0.2217 0.40 5szo:A, 5szp:A, 5szp:B
7 3i46:A 289 84 0.0648 0.0727 0.2500 1.6 3i46:B
8 4cjn:A 642 53 0.0401 0.0202 0.2453 2.8 4bl3:A, 4bl3:B, 4cjn:B, 4cpk:A, 4cpk:B, 4dki:A, 4dki:B, 6h5o:B, 5m18:A, 5m18:B, 5m19:A, 5m19:B, 5m1a:A, 5m1a:B, 1mwt:A, 1mwt:B, 1mwu:A, 1mwu:B, 6q9n:A, 3zfz:A, 3zfz:B, 3zg0:A, 3zg0:B, 3zg5:A, 3zg5:B
9 5nuo:D 200 67 0.0710 0.1150 0.3433 4.2 8i8r:D, 5nuo:B, 5nuo:F, 5nup:E, 5nur:D
10 2w2h:A 263 29 0.0340 0.0418 0.3793 4.6 5l1z:B, 2w2h:B
11 6rm3:SD0 210 78 0.0648 0.1000 0.2692 6.9
12 2dds:A 299 101 0.0833 0.0903 0.2673 9.9 2ddr:A, 2ddr:B, 2ddr:C, 2ddr:D, 2dds:B, 2dds:C, 2dds:D, 2ddt:A, 2ddt:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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