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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PPNNSNAAEDDLPTVELQGVVPRGVNLQEFLNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDP
RRDLFRVEYVIGRYPQENKGTYIPVPIVSELQSGKWGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVAVWTPYGVLRTSR
NPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKTRSWSYGQFEDGILDTCLYVMDRAQMDLSGRGN
PIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYRSSENPVRYGQCWVFAGVFNTFLRCLGIPARI
VTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASV
QAIKHGHVCFQFDAPFVFAEVNSDLIYITAHVVENVDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETALM
YGRSNVDMDFEVENAVLGKDFKLSITFRNNSHNRYTITAYLSANITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAG
EYMGQLLEQASLHFFVTARINETRDVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVIVEFTNPLKETLRNVWVHLDGPGV
TRPMKKMFREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQIQRRPS

The query sequence (length=698) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1ex0:B 716 711 0.9885 0.9637 0.9705 0.0 1ex0:A, 1ggy:A, 1ggy:B, 4kty:A, 4kty:B, 5mhl:A, 5mhl:B, 5mhn:A, 1qrk:A, 1qrk:B
2 5mhn:B 685 693 0.9814 1.0000 0.9885 0.0 5mhm:A, 5mhm:B, 5mho:A, 5mho:B
3 4pyg:A 685 680 0.3739 0.3810 0.3838 1.33e-136 6a8p:A, 6a8p:B, 6a8p:C, 9bc3:A, 9bc3:B, 9bc4:A, 1kv3:A, 1kv3:B, 1kv3:C, 1kv3:D, 1kv3:E, 1kv3:F, 6kzb:A, 6kzb:B, 3ly6:A, 3ly6:B, 3ly6:C, 4pyg:B, 4pyg:E, 8tr9:A
4 2q3z:A 655 666 0.3696 0.3939 0.3874 1.64e-135 9bc2:A, 3s3j:A
5 1l9m:B 681 680 0.3381 0.3465 0.3471 2.02e-129 1l9m:A, 1l9n:A, 1l9n:B, 1nud:A, 1nud:B, 1nuf:A, 1nug:A, 1nug:B, 8oxv:A, 8oxw:A, 8oxx:A
6 1g0d:A 666 677 0.3410 0.3574 0.3516 1.05e-128
7 6kzb:C 649 676 0.3625 0.3898 0.3743 4.04e-126
8 3s3s:A 620 665 0.3410 0.3839 0.3579 1.36e-110 3s3p:A
9 3ef1:A 372 40 0.0244 0.0457 0.4250 0.11 3ef0:A, 4xpz:A, 4xq0:A
10 5d2e:A 485 51 0.0244 0.0351 0.3333 0.76
11 2xr7:A 452 42 0.0258 0.0398 0.4286 6.7
12 3dc8:A 483 39 0.0186 0.0269 0.3333 7.5 3dc8:B
13 7nac:x 539 61 0.0301 0.0390 0.3443 8.0 7nad:x, 7r72:x, 7r7a:x
14 3plv:A 80 66 0.0215 0.1875 0.2273 8.4 3plu:A, 3plu:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218