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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PPLDLNNIQGDILGGLPKRTETYFFFDVTNVDQFKANMAHFIPHIKTSAGIIKDREAIKEHKRQKKPGLVPMAAVNVSFS
HLGLQKLGITDDLSDNAFTTGQRKDAEILGDPGSKNGDAFTPAWEAPFLKDIHGVIFVAGDCHGSVNKKLDEIKHIFGVG
TSHASISEVTHVRGDVRPGDVHAHEHFGYLDGISHPAVEQFDQNPLPGQDPIRPGFILAKENGDSRAAARPDWAKDGSFL
TFRYLFQMVPEFDDFLESNPIVLPGLSRKEGSELLGARIVGRWKSGAPIEITPLKDDPKLAADAQRNNKFDFGDSLVRGD
QTKCPFAAHIRKTYPRNDLEGPPLKADIDNRRIIRRGIQFGPEVTSQEHHDKKTHHGRGLLFVCYSSSIDDGFHFIQESW
ANAPNFPVNAVTSAGPIPPLDGVVPGFDAIIGQKVGGGIRQISGTNPNDPTTNITLPDQDFVVPRGGEYFFSPSITALKT
KFAI

The query sequence (length=484) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6fsk:A 484 484 1.0000 1.0000 1.0000 0.0 6fsk:B, 6fsl:A, 6fsl:B
2 7anv:A 467 489 0.6116 0.6338 0.6053 0.0
3 3afv:A 439 485 0.4360 0.4806 0.4351 5.68e-121 2d3q:A, 2d3q:B, 3mm1:A, 3mm2:A, 3mm3:A, 3vxi:A, 3vxj:A
4 4au9:A 448 488 0.4029 0.4353 0.3996 1.34e-107 5ag0:A, 5ag0:B, 5ag1:A, 5ag1:B, 4au9:B, 5ikd:A, 5ikg:A, 4uzi:A, 4uzi:B, 4w7j:A, 4w7j:B, 4w7j:C, 4w7j:D, 4w7k:A, 4w7k:B, 4w7l:A, 4w7l:B, 4w7m:A, 4w7m:B, 4w7n:A, 4w7n:B, 4w7o:A
5 7d8m:A 451 486 0.4174 0.4479 0.4156 2.26e-102
6 8re3:A 445 420 0.2665 0.2899 0.3071 6.73e-42 8re2:A, 8re3:B
7 5c2i:A 468 500 0.3140 0.3248 0.3040 9.11e-34 5c2i:B, 5c2i:C, 5c2i:D
8 4g2c:B 463 492 0.2872 0.3002 0.2825 1.74e-26 4g2c:A
9 6jbn:A 391 178 0.1012 0.1253 0.2753 5.11e-04 6jbn:B
10 2y4e:A 384 168 0.0888 0.1120 0.2560 0.012 3o72:A, 3o72:B, 3o72:C, 3o72:D, 2y4e:B, 2y4f:A, 2y4f:B
11 5fw4:A 368 95 0.0537 0.0707 0.2737 1.3 5fw4:B
12 2aaa:A 476 178 0.0806 0.0819 0.2191 3.6
13 5ipx:A 282 44 0.0310 0.0532 0.3409 4.7
14 1lqk:A 134 73 0.0393 0.1418 0.2603 7.2 1lqk:B, 1lqo:A, 1lqo:B, 1lqp:A, 1lqp:B, 1nki:A, 1nki:B, 1nnr:A, 1nnr:B
15 4k50:A 460 55 0.0331 0.0348 0.2909 8.9 4k50:I, 4k50:E, 4k50:M, 1tp7:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218