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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PPFTVGREDPRYIELSHSDNHRFVVEPEEFFLPATPDDVVASLQKAVTEGRGVACRSGGHCGQDFVGTPRRDLVLDLHNL
HAIGPAADGAGVRVGSGATVDQVQKALFRRWNAALPLGACSAVGMGGLVAGGGYGPLSRQLGLVVDHLHAVEVAVVDESR
TVRLVTARADDTGDLGELFWAHTGGGGGNFGVVTAYEFRSPEHLATEPVGLPRAAGRLHVQKVVFPWAMIDETSFVTVMR
RFFEWHERHSEPGSPESSLFATFFVNHVSSGVLQLMVQQDADVDPEGEILARFVASLTEGTGVVGIPRGGVMSWLTGTRY
MSQADCGDVMGARSASKSAYHRAAPTDEQLSVLHRHLHADHPGQASYVMFNSYGGEINRRGPSDAAVPQRDSVVKSSWFS
AWQDAELDELHLGWLRGLYEEFFAGTGGVPVTGGRTDGCYINYPDADLLDPARNRSGEPWHHLYYKDNYARLRSAKRAWD
PLNTFHHSMSIGL

The query sequence (length=493) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3pop:A 493 493 1.0000 1.0000 1.0000 0.0 3pop:B, 3pop:C, 3pop:D, 3pqb:A, 3pqb:B, 3pqb:C, 3pqb:D
2 5i1v:A 498 491 0.4118 0.4076 0.4134 2.65e-105 5i1v:B, 5i1v:C, 5i1v:D, 5i1w:A, 5i1w:B, 5i1w:C, 5i1w:D
3 2y08:B 500 491 0.4138 0.4080 0.4155 1.19e-103 2y08:A, 2y3r:A, 2y3r:B, 2y3r:C, 2y3r:D, 2y3s:A, 2y3s:B, 2y4g:A, 2y4g:B
4 2ipi:A 492 490 0.4037 0.4045 0.4061 9.15e-101 2ipi:B, 2ipi:C, 2ipi:D
5 5awv:B 498 497 0.3834 0.3795 0.3803 3.88e-95 5awv:C, 5awv:A, 5awv:D, 2wdw:A, 2wdw:B
6 7zzk:B 489 510 0.3631 0.3661 0.3510 3.04e-65 7zzk:A
7 4ud8:A 500 499 0.2617 0.2580 0.2585 1.05e-26 4ud8:B
8 3vte:A 502 521 0.2535 0.2490 0.2399 2.07e-23
9 5d79:A 498 508 0.2495 0.2470 0.2421 1.89e-20 5d79:B
10 6jqh:B 513 521 0.2454 0.2359 0.2322 2.43e-19 6jqh:A
11 6eo4:A 463 482 0.2312 0.2462 0.2365 3.21e-19 6eo4:B, 6eo5:A, 6eo5:B
12 7yav:A 501 510 0.2414 0.2375 0.2333 7.37e-19 7yav:B
13 7e2v:A 500 518 0.2779 0.2740 0.2645 8.10e-19 7e2v:B
14 5k8e:A 473 508 0.2515 0.2622 0.2441 3.23e-16 5l6f:A, 5l6g:A
15 8ate:A 502 482 0.2414 0.2371 0.2469 3.13e-14
16 6y0r:AAA 468 196 0.1197 0.1261 0.3010 1.86e-11
17 6y0r:AAA 468 116 0.0609 0.0641 0.2586 0.002
18 3d2j:A 502 513 0.2414 0.2371 0.2320 4.34e-10 3d2d:A, 3d2h:A, 4ec3:A, 3fw7:A, 3fw8:A, 3fw9:A, 3fwa:A, 3gsy:A, 4pzf:A, 4pzf:B, 4pzf:C, 4pzf:D
19 4dns:A 486 515 0.2394 0.2428 0.2291 1.48e-09 4dns:B
20 3rj8:A 473 506 0.2394 0.2495 0.2332 5.15e-09 3rja:A
21 4pve:A 490 171 0.1116 0.1122 0.3216 2.80e-08 4pvh:A, 4pvj:A, 4pvk:A, 4pwb:A, 4pwc:A, 3tsh:A, 3tsj:A, 3tsj:B
22 4pve:A 490 138 0.0751 0.0755 0.2681 8.79e-04 4pvh:A, 4pvj:A, 4pvk:A, 4pwb:A, 4pwc:A, 3tsh:A, 3tsj:A, 3tsj:B
23 6yjo:A 475 197 0.1014 0.1053 0.2538 3.26e-08
24 2bvf:A 453 167 0.1116 0.1214 0.3293 5.16e-08 2bvf:B, 2bvg:A, 2bvg:B, 2bvg:C, 2bvg:D, 2bvh:A, 2bvh:B, 2bvh:C, 2bvh:D
25 2bvf:A 453 44 0.0304 0.0331 0.3409 0.35 2bvf:B, 2bvg:A, 2bvg:B, 2bvg:C, 2bvg:D, 2bvh:A, 2bvh:B, 2bvh:C, 2bvh:D
26 3w8w:B 461 167 0.1339 0.1432 0.3952 8.19e-08 6foq:A, 6foq:B, 6foq:C, 6foq:D, 6fow:A, 6fow:B, 6fow:C, 6fow:D, 6fp3:A, 6fp3:B, 6fp3:C, 6fp3:D, 6fy8:A, 6fy9:A, 6fya:A, 6fya:B, 6fyb:A, 6fyb:B, 6fyb:C, 6fyb:D, 6fyc:A, 6fyc:B, 6fyd:A, 6fyd:B, 6fyd:C, 6fyd:D, 6fye:A, 6fye:B, 6fyf:A, 6fyf:B, 6fyf:C, 6fyf:D, 6fyg:A, 6fyg:B, 6fyg:C, 6fyg:D, 3w8w:A, 3w8x:A, 3w8x:B, 3w8z:A, 3w8z:B, 4xlo:A, 4xlo:B, 4xlo:C, 4xlo:D
27 3w8w:B 461 187 0.0913 0.0976 0.2406 0.001 6foq:A, 6foq:B, 6foq:C, 6foq:D, 6fow:A, 6fow:B, 6fow:C, 6fow:D, 6fp3:A, 6fp3:B, 6fp3:C, 6fp3:D, 6fy8:A, 6fy9:A, 6fya:A, 6fya:B, 6fyb:A, 6fyb:B, 6fyb:C, 6fyb:D, 6fyc:A, 6fyc:B, 6fyd:A, 6fyd:B, 6fyd:C, 6fyd:D, 6fye:A, 6fye:B, 6fyf:A, 6fyf:B, 6fyf:C, 6fyf:D, 6fyg:A, 6fyg:B, 6fyg:C, 6fyg:D, 3w8w:A, 3w8x:A, 3w8x:B, 3w8z:A, 3w8z:B, 4xlo:A, 4xlo:B, 4xlo:C, 4xlo:D
28 6f72:A 548 172 0.1034 0.0931 0.2965 8.36e-08 6f73:A, 6f73:B
29 6f72:A 548 33 0.0264 0.0237 0.3939 0.23 6f73:A, 6f73:B
30 3pm9:A 465 245 0.1318 0.1398 0.2653 3.32e-06 3pm9:B, 3pm9:C, 3pm9:D, 3pm9:E, 3pm9:F
31 6yji:A 477 181 0.0913 0.0943 0.2486 7.08e-06 6yji:B
32 6yji:A 477 64 0.0406 0.0419 0.3125 1.1 6yji:B
33 2axr:A 479 194 0.1258 0.1294 0.3196 1.64e-05 3hsu:A, 1zr6:A
34 2axr:A 479 54 0.0325 0.0334 0.2963 2.4 3hsu:A, 1zr6:A
35 6hfw:A 429 164 0.1014 0.1166 0.3049 9.34e-05 4fdn:A, 4fdo:A, 4fdp:A, 4fdp:B, 4feh:A, 4ff6:A, 4ff6:B, 6g83:A, 6g83:B, 6hez:A, 6hez:B, 6hf0:A, 6hf0:B, 6hf3:A, 6hf3:B, 6hfv:A, 6hfv:B, 6hfw:B, 4kw5:A, 4kw5:B, 4ncr:A, 4ncr:B, 5oel:B, 5oep:A, 5oep:B, 5oeq:A, 5oeq:B, 4p8c:B, 4p8h:A, 4p8h:B, 4p8k:B, 4p8l:B, 4p8m:A, 4p8n:B, 4p8p:B, 4p8t:B, 4p8y:B, 4pfa:A, 4pfa:B, 4pfd:A
36 4p8l:A 457 120 0.0771 0.0832 0.3167 0.001 5oel:A, 4p8c:A, 4p8k:A, 4p8n:A, 4p8p:A, 4p8t:A, 4p8y:A
37 4pfd:B 410 120 0.0771 0.0927 0.3167 0.001 4p8m:B
38 4aut:A 419 160 0.0953 0.1122 0.2938 0.007 4f4q:A
39 6lpn:B 467 139 0.0710 0.0749 0.2518 0.12 6lpn:A, 6lpp:A, 6lpp:B, 6lpq:A, 6lpq:B, 6lpt:A, 6lpt:B, 6lpu:A, 6lpu:B, 6lpx:A, 6lpx:B
40 8ck6:A 499 188 0.1156 0.1142 0.3032 0.16 8cj9:A, 8cj9:B, 6yaq:A
41 2wtz:C 439 90 0.0649 0.0729 0.3556 1.1
42 2wtz:B 508 74 0.0588 0.0571 0.3919 3.1 2wtz:A, 2wtz:D, 2xja:A, 2xja:B, 2xja:C, 2xja:D
43 5hwg:A 175 63 0.0385 0.1086 0.3016 4.2 5hwh:A
44 2hqy:A 298 58 0.0345 0.0570 0.2931 4.7
45 6f74:A 572 29 0.0243 0.0210 0.4138 8.8 6f74:B, 6f74:C, 6f74:D
46 6a6e:A 422 31 0.0264 0.0308 0.4194 9.9 6a6e:B, 6a6e:C, 6a6e:D, 6a6g:A, 6a6g:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218