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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PNKLTLKIGRAEGRPGDTVEIPVNLYGVPQKGIASGDFVVSYDPNVLEIIEIEPGELIVDPNPTKSFDTAVYPDRKMIVF
LFAEDSGTGAYAITEDGVFATIVAKVKEGAPEGFSAIEISEFGAFADNDLVEVETDLINGGVLVTNKPVIEGYKVSGYIL
PDFSFDATVAPLVKAGFKVEIVGTELYAVTDANGYFEITGVPANASGYTLKISRATYLDRVIANVVVTGDTSVSTSQAPI
MMWVGDIVKDNSINLLDVAEVIRCFNATKGSANYVEELDINRNGAINMQDIMIVHKHFGATSSDYDAQ

The query sequence (length=308) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4fl4:I 309 308 1.0000 0.9968 1.0000 0.0 2b59:B, 4fl4:C, 4fl4:F, 4fl4:L, 5g5d:B, 3kcp:A
2 4u3s:B 156 158 0.2792 0.5513 0.5443 4.87e-51 4wi0:B
3 5m0y:B 157 157 0.2338 0.4586 0.4586 6.53e-39 5k39:B
4 4uyq:A 143 110 0.1071 0.2308 0.3000 4.08e-08
5 2y3n:B 60 59 0.0714 0.3667 0.3729 0.002
6 5hlo:C 93 26 0.0390 0.1290 0.4615 0.15 6ds2:A, 6ds2:C, 6ds2:E, 6ds2:G, 4ggf:A, 4ggf:K, 4ggf:S, 4ggf:U, 5hlo:A, 5hlo:B, 5hlo:D, 5hlv:A, 5hlv:D, 5hlv:B, 5hlv:H, 5hlv:C, 5hlv:E, 5hlv:F, 5hlv:G, 1mr8:A, 1mr8:B, 7quv:A, 8sjb:A, 8sjb:B, 8sjc:A, 8sjc:B, 5w1f:A, 5w1f:C, 5w1f:G, 5w1f:E, 4xjk:A, 4xjk:C, 4xjk:E, 4xjk:G, 4xjk:I, 1xk4:A, 1xk4:B, 1xk4:E, 1xk4:F, 1xk4:I, 1xk4:J
7 8rsj:A 262 46 0.0584 0.0687 0.3913 0.17 8rsi:A, 8rsi:B, 8rsj:B, 8rsk:A, 8rsk:B, 8rsk:C
8 2l4h:A 184 91 0.0747 0.1250 0.2527 0.47 2l4i:A, 2lm5:A, 6ocx:D, 6ocx:C, 6ocx:A, 6ocx:B, 6od0:A, 6od0:B, 1xo5:A, 1xo5:B, 1y1a:A, 1y1a:B
9 2y3n:D 49 21 0.0357 0.2245 0.5238 0.72
10 2ccl:B 62 56 0.0455 0.2258 0.2500 1.2 2ccl:D, 1ohz:B
11 3sfw:A 461 44 0.0552 0.0369 0.3864 4.1 3sfw:B
12 1ytm:A 517 81 0.0844 0.0503 0.3210 6.2 1ytm:B
13 7xpx:K 167 37 0.0357 0.0659 0.2973 6.9 6boz:A, 6boz:B, 2bqz:A, 2bqz:E, 3f9w:B, 3f9w:A, 3f9w:C, 3f9w:D, 3f9x:B, 3f9x:A, 3f9x:C, 3f9x:D, 3f9y:A, 3f9y:B, 3f9z:B, 3f9z:A, 3f9z:C, 3f9z:D, 4ij8:A, 4ij8:B, 5t5g:A, 5teg:A, 5teg:B, 5th7:A, 5th7:B, 5w1y:A, 5w1y:B, 1zkk:A, 1zkk:B, 1zkk:C, 1zkk:D
14 7b7z:A 340 178 0.1201 0.1088 0.2079 8.6 7b80:A, 6i7g:A, 6i7g:B, 6i7i:A, 6i7k:A, 6i7l:A, 4u07:A, 4u07:B, 4u0s:A, 4u0s:B, 4u0u:A, 4u0u:B, 4u0z:A, 4u0z:B, 4u0z:C, 4u0z:D, 4u0z:E, 4u0z:F, 4u0z:G, 4u0z:H, 6zmd:B
15 5a9z:AS 101 24 0.0357 0.1089 0.4583 8.7 5aa0:AS, 7azo:L21A, 7azo:L21B, 7azs:L21A, 7azs:L21B, 9b00:1V, 9b00:2V, 6b4v:S, 6b4v:WB, 6boh:S, 6boh:XB, 6bok:S, 6bok:VB, 6buw:RV, 6buw:YV, 6bz6:RV, 6bz6:YV, 6bz7:RV, 6bz7:YV, 6bz8:RV, 6bz8:YV, 6c5l:BV, 6c5l:DV, 6cae:1V, 6cae:2V, 6cfj:1V, 6cfj:2V, 6cfk:1V, 6cfk:2V, 6cfl:1V, 6cfl:2V, 8cvj:1V, 8cvj:2V, 8cvk:1V, 8cvk:2V, 8cvl:1V, 8cvl:2V, 5czp:YV, 5czp:RV, 6czr:1V, 6czr:2V, 5d8b:P, 5d8b:LB, 5dfe:YV, 5dfe:RV, 5dox:1V, 5dox:2V, 5doy:1V, 5doy:2V, 5e7k:D8, 5e7k:95, 5e81:D8, 5e81:95, 8ekb:1V, 8ekb:2V, 5el4:D8, 5el4:95, 5el5:D8, 5el5:95, 5el6:D8, 5el6:95, 5el7:D8, 5el7:95, 8ev6:1V, 8ev6:2V, 8ev7:1V, 8ev7:2V, 5f8k:1V, 5f8k:2V, 8fc1:1V, 8fc1:2V, 8fc2:1V, 8fc2:2V, 8fc3:1V, 8fc3:2V, 8fc4:1V, 8fc4:2V, 8fc5:1V, 8fc5:2V, 8fc6:1V, 8fc6:2V, 5fdu:1V, 5fdu:2V, 5fdv:1V, 5fdv:2V, 6fkr:1V, 6fkr:2V, 8fom:RV, 8fom:YV, 8fon:RV, 8fon:YV, 8g29:1V, 8g29:2V, 8g2a:1V, 8g2a:2V, 8g2b:1V, 8g2b:2V, 8g2c:1V, 8g2c:2V, 8g2d:1V, 8g2d:2V, 6gsj:D8, 6gsj:95, 6gsk:D8, 6gsk:95, 6gsl:D8, 6gsl:95, 6gzq:Q1, 6gzx:Q1, 6gzx:Q2, 6gzz:Q1, 6gzz:Q2, 5hau:1T, 5hau:2T, 5hcp:1V, 5hcp:2V, 5hcq:1V, 5hcq:2V, 5hcr:1V, 5hcr:2V, 5hd1:1V, 5hd1:2V, 5ib7:D8, 5ib7:95, 5ib8:D8, 5ib8:95, 5ibb:D8, 5ibb:95, 5imq:n, 5imr:n, 5j30:RV, 5j30:YV, 5j3c:RV, 5j3c:YV, 5j4b:1V, 5j4b:2V, 5j4c:1V, 5j4c:2V, 5j4d:S, 5j4d:XB, 5j8b:V, 7jql:1V, 7jql:2V, 7jqm:1V, 7jqm:2V, 4l47:RV, 4l47:YV, 4l71:RV, 4l71:YV, 4lel:RV, 4lel:YV, 4lfz:RV, 4lfz:YV, 7lh5:BV, 7lh5:DV, 4lnt:RV, 4lnt:YV, 4lsk:RV, 4lsk:YV, 4lt8:RV, 4lt8:YV, 7md7:1V, 7md7:2V, 6n1d:AL21, 6n1d:BL21, 6n9e:1V, 6n9e:2V, 6n9f:1V, 6n9f:2V, 5ndj:D8, 5ndj:95, 5ndk:D8, 5ndk:95, 6nd5:1V, 6nd5:2V, 6nd6:1V, 6nd6:2V, 6ndk:RV, 6ndk:YV, 6nsh:RV, 6nsh:YV, 6nta:RV, 6nta:YV, 6nuo:RV, 6nuo:YV, 6nwy:RV, 6nwy:YV, 6o3m:RV, 6o3m:YV, 6o97:1V, 6o97:2V, 6of1:1V, 6of1:2V, 6of6:RV, 6of6:YV, 6oj2:RV, 6oj2:YV, 6ope:RV, 6ope:YV, 6ord:RV, 6ord:YV, 6osi:RV, 6osi:YV, 5ot7:w, 6otr:RV, 6otr:YV, 6oxa:RV, 6oxa:YV, 6oxi:RV, 6oxi:YV, 4p6f:RV, 4p6f:YV, 4p70:RV, 4p70:YV, 6q95:R, 6qnq:D8, 6qnq:95, 6qnr:D8, 6qnr:95, 7rq8:1V, 7rq8:2V, 7rq9:1V, 7rq9:2V, 7rqa:1V, 7rqa:2V, 7rqb:1V, 7rqb:2V, 7rqc:1V, 7rqc:2V, 7rqd:1V, 7rqd:2V, 7rqe:1V, 7rqe:2V, 8t8b:1V, 8t8b:2V, 8t8c:1V, 8t8c:2V, 4tua:RV, 4tua:YV, 4tub:RV, 4tub:YV, 4tuc:RV, 4tuc:YV, 4tud:RV, 4tud:YV, 4tue:RV, 4tue:YV, 7u2h:1V, 7u2h:2V, 7u2i:1V, 7u2i:2V, 7u2j:1V, 7u2j:2V, 6ucq:1V, 6ucq:2V, 8ud6:1V, 8ud6:2V, 8ud7:1V, 8ud7:2V, 8ud8:1V, 8ud8:2V, 6uo1:1V, 6uo1:2V, 5uq7:V, 5uq8:V, 8uvr:1V, 8uvr:2V, 8uvs:1V, 8uvs:2V, 4v4i:P, 4v4j:P, 4v4x:BU, 4v4y:BU, 4v4z:BU, 4v51:BV, 4v51:DV, 4v5a:BV, 4v5a:DV, 4v5c:BV, 4v5c:DV, 4v5d:BV, 4v5d:DV, 4v5e:BV, 4v5e:DV, 4v5f:BV, 4v5f:DV, 4v5g:BV, 4v5g:DV, 4v5j:BV, 4v5j:DV, 4v5k:BV, 4v5k:DV, 4v5l:BV, 4v5m:BV, 4v5n:BV, 4v5p:BV, 4v5p:DV, 4v5q:BV, 4v5q:DV, 4v5r:BV, 4v5r:DV, 4v5s:BV, 4v5s:DV, 4v63:BV, 4v63:DV, 4v67:BV, 4v67:DV, 4v68:BV, 4v6a:BV, 4v6a:DV, 4v6f:A2, 4v6f:D2, 4v6g:B2, 4v6g:D2, 4v7j:AV, 4v7j:BV, 4v7k:AV, 4v7k:BV, 4v7l:BV, 4v7l:DV, 4v7m:BV, 4v7m:DV, 4v7p:BR, 4v7p:CR, 4v7w:BV, 4v7w:DV, 4v7x:BV, 4v7x:DV, 4v7y:BV, 4v7y:DV, 4v7z:BV, 4v7z:DV, 4v83:BR, 4v83:DR, 4v84:BR, 4v84:DR, 4v87:A2, 4v87:D2, 4v8a:AV, 4v8a:BV, 4v8b:B2, 4v8b:D2, 4v8c:A2, 4v8c:B2, 4v8d:B2, 4v8d:D2, 4v8e:A2, 4v8e:C2, 4v8f:A2, 4v8f:D2, 4v8g:BV, 4v8g:DV, 4v8h:BV, 4v8h:DV, 4v8i:BV, 4v8i:DV, 4v8j:BV, 4v8j:DV, 4v8n:BV, 4v8n:DV, 4v8o:BV, 4v8q:AV, 4v8u:BV, 4v8u:DV, 4v8x:BV, 4v8x:DV, 5v8i:1V, 5v8i:2V, 4v90:BV, 4v95:BV, 4v95:DV, 4v97:BV, 4v97:DV, 4v9a:B2, 4v9a:D2, 4v9b:B2, 4v9b:D2, 4v9h:BV, 4v9i:BV, 4v9i:DV, 4v9j:BV, 4v9j:DV, 4v9k:BV, 4v9k:DV, 4v9l:BV, 4v9l:DV, 4v9m:BV, 4v9m:DV, 4v9n:BV, 4v9n:DV, 4v9q:AR, 4v9q:CR, 4v9r:BV, 4v9r:DV, 4v9s:BV, 4v9s:DV, 5vp2:1V, 5vp2:2V, 5vpo:RV, 5vpo:YV, 5vpp:RV, 5vpp:YV, 8vtu:1V, 8vtu:2V, 8vtv:1V, 8vtv:2V, 8vtw:1V, 8vtw:2V, 8vtx:1V, 8vtx:2V, 8vty:1V, 8vty:2V, 1vvj:RV, 1vvj:YV, 1vy4:BV, 1vy4:DV, 1vy5:BV, 1vy5:DV, 1vy6:BV, 1vy6:DV, 1vy7:BV, 1vy7:DV, 4w29:BV, 4w29:DV, 4w2e:V, 4w2f:BV, 4w2f:DV, 4w2g:BV, 4w2g:DV, 4w2h:BV, 4w2h:DV, 4w2i:BV, 4w2i:DV, 4w4g:RV, 4w4g:YV, 5w4k:1V, 5w4k:2V, 5wis:1V, 5wis:2V, 5wit:1V, 5wit:2V, 4wpo:AV, 4wpo:CV, 4wq1:D8, 4wq1:95, 4wqf:AV, 4wqf:CV, 4wqr:D8, 4wqr:95, 4wqu:AV, 4wqu:CV, 4wqy:AV, 4wqy:CV, 4wr6:D8, 4wr6:95, 4wra:D8, 4wra:95, 4wro:D8, 4wsd:D8, 4wsd:95, 4wsm:D8, 4wsm:95, 4wt1:D8, 4wt1:95, 4wt8:CU, 4wt8:DU, 4wu1:D8, 4wu1:95, 4wzd:D8, 4wzd:95, 4wzo:D8, 4wzo:95, 4xej:AL21, 4xej:BL21, 6xhv:1V, 6xhv:2V, 6xhw:1V, 6xhw:2V, 6xhx:1V, 6xhx:2V, 6xhy:1V, 6xhy:2V, 6xqd:1V, 6xqd:2V, 6xqe:1V, 6xqe:2V, 4y4o:1V, 4y4o:2V, 4y4p:1V, 4y4p:2V, 4ypb:RV, 4ypb:YV, 4yzv:RV, 4yzv:YV, 4z3s:1V, 4z3s:2V, 4z8c:1V, 4z8c:2V, 4zer:1V, 4zer:2V, 5zlu:o, 4zsn:RV, 4zsn:YV

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218