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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYA
KTDSDII

The query sequence (length=87) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4pkd:B 240 87 1.0000 0.3625 1.0000 2.07e-59 1aud:A, 7b0y:c, 3bo2:A, 3bo3:A, 3bo4:A, 4c4w:A, 4c4w:E, 3cul:A, 3cul:B, 3cun:A, 3cun:B, 7d7v:C, 5ddo:G, 5ddo:C, 5ddp:D, 5ddp:C, 5ddq:D, 5ddq:C, 5ddr:D, 5ddr:C, 7dlz:A, 7dlz:B, 1drz:A, 7dwh:A, 7dwh:B, 1dz5:A, 1dz5:B, 3egz:A, 5fj4:A, 5fj4:E, 3g8s:A, 3g8s:B, 3g8s:C, 3g8s:D, 3g8t:A, 3g8t:B, 3g8t:C, 3g8t:D, 3g96:A, 3g96:B, 3g96:C, 3g96:D, 3g9c:A, 3g9c:B, 3g9c:C, 3g9c:D, 8gxb:C, 8gxb:D, 8gxb:F, 8gxc:C, 8gxc:D, 8gxc:F, 3hhn:B, 3hhn:D, 3iin:A, 3irw:P, 3iwn:C, 3iwn:D, 8jy0:A, 8jy0:C, 8jy0:E, 3k0j:A, 3k0j:B, 3l3c:A, 3l3c:B, 3l3c:C, 3l3c:D, 6las:E, 6las:D, 6las:C, 6lau:E, 6lau:D, 6lau:C, 6lax:D, 6lax:E, 6lax:C, 6laz:D, 6laz:E, 6laz:C, 1m5k:C, 1m5k:F, 1m5o:C, 1m5o:F, 1m5p:C, 1m5p:F, 1m5v:C, 1m5v:F, 3mum:P, 3mur:P, 3mut:P, 3muv:P, 3mxh:P, 2nz4:A, 2nz4:B, 2nz4:C, 2nz4:D, 2oih:A, 2oj3:A, 3p49:B, 4pr6:A, 4prf:A, 7qr3:A, 7qr3:B, 7qr4:A, 6qx9:1A, 3r1h:A, 3r1h:D, 3r1l:A, 3r1l:D, 1sj3:P, 1sj4:P, 1sjf:A, 6sqn:A, 6sqn:B, 6sqn:C, 6sqq:AAA, 6sqq:BBB, 6sqq:CCC, 1u6b:A, 3ucu:P, 3ucz:P, 3ud3:P, 3ud4:P, 1urn:A, 1urn:B, 1urn:C, 1vbx:A, 1vby:A, 1vbz:A, 1vc0:A, 1vc5:A, 1vc6:A, 7vpx:M, 4w90:B, 4w92:B, 1zzn:A
2 6xh2:A 93 86 0.8621 0.8065 0.8721 5.28e-51 6cmn:A, 3k0j:D, 3k0j:C, 6xh0:A, 6xh1:A, 6xh3:A
3 7abg:B 169 87 0.7701 0.3964 0.7701 1.47e-48 7a5p:X, 1a9n:B, 1a9n:D, 7abi:B, 6ah0:p, 6ahd:p, 8c6j:Y, 8ch6:s, 7evo:G, 9fmd:p, 8h6e:2C, 8h6j:2C, 8h6k:2C, 8h6l:2C, 8hk1:G, 8i0p:p, 8i0r:p, 8i0s:p, 8i0t:p, 8i0u:p, 8i0v:p, 8i0w:p, 6icz:p, 6id0:p, 6id1:p, 5mqf:X, 6qdv:Y, 8qo9:2B, 6qx9:2B, 8qxd:2B, 8qzs:2B, 8r08:2B, 8r09:2B, 8r0a:2B, 8r0b:2B, 8rm5:2B, 7vpx:G, 7w59:p, 7w5a:p, 7w5b:p, 5xjc:p, 6y53:b, 6y5q:b, 5yzg:p, 5z56:p, 5z57:p, 5z58:p
4 7abg:B 169 83 0.3103 0.1598 0.3253 0.11 7a5p:X, 1a9n:B, 1a9n:D, 7abi:B, 6ah0:p, 6ahd:p, 8c6j:Y, 8ch6:s, 7evo:G, 9fmd:p, 8h6e:2C, 8h6j:2C, 8h6k:2C, 8h6l:2C, 8hk1:G, 8i0p:p, 8i0r:p, 8i0s:p, 8i0t:p, 8i0u:p, 8i0v:p, 8i0w:p, 6icz:p, 6id0:p, 6id1:p, 5mqf:X, 6qdv:Y, 8qo9:2B, 6qx9:2B, 8qxd:2B, 8qzs:2B, 8r08:2B, 8r09:2B, 8r0a:2B, 8r0b:2B, 8rm5:2B, 7vpx:G, 7w59:p, 7w5a:p, 7w5b:p, 5xjc:p, 6y53:b, 6y5q:b, 5yzg:p, 5z56:p, 5z57:p, 5z58:p
5 6f4h:C 96 87 0.8161 0.7396 0.8161 5.32e-43 6f4g:B, 6f4g:E, 6f4h:A, 6f4h:E
6 8ro1:p 76 76 0.6092 0.6974 0.6974 1.05e-38
7 3jb9:k 89 84 0.4483 0.4382 0.4643 5.70e-25
8 7b9v:Y 88 85 0.3103 0.3068 0.3176 9.44e-15 6bk8:r, 7dco:p, 6exn:Y, 6g90:Y, 5gmk:a, 6j6g:a, 6j6h:a, 6j6n:a, 6j6q:a, 5lj3:Y, 5lj5:Y, 5mq0:Y, 5nrl:Y, 7oqb:Y, 7oqe:Y, 5wsg:X, 5y88:p, 5ylz:p, 5zwm:p, 5zwo:p
9 3lqv:B 115 67 0.2759 0.2087 0.3582 6.29e-09 2f9j:B, 3lqv:A, 7q4o:F, 8qo9:B6, 8qxd:B6, 8qzs:B6, 8r08:B6, 8r09:B6, 8r0a:B6, 8r0b:B6, 8rm5:B6
10 2fy1:A 108 82 0.2989 0.2407 0.3171 6.27e-08
11 2mb0:B 95 79 0.2759 0.2526 0.3038 3.63e-07
12 7q33:A 93 86 0.2644 0.2473 0.2674 6.36e-07 6pai:D, 6q0r:D, 6q0v:D, 6q0w:D, 6sj7:C, 6ud7:C, 6ue5:C
13 2leb:A 101 81 0.2414 0.2079 0.2593 3.93e-06 2lec:A
14 4f02:A 175 86 0.3103 0.1543 0.3140 6.39e-05 1cvj:A, 1cvj:B, 1cvj:C, 1cvj:D, 1cvj:E, 1cvj:F, 1cvj:G, 1cvj:H, 4f02:D
15 4f02:A 175 71 0.2759 0.1371 0.3380 5.53e-04 1cvj:A, 1cvj:B, 1cvj:C, 1cvj:D, 1cvj:E, 1cvj:F, 1cvj:G, 1cvj:H, 4f02:D
16 7s7b:C 79 80 0.2644 0.2911 0.2875 7.12e-05 7s7b:G, 7s7c:C
17 7qde:B 169 62 0.2184 0.1124 0.3065 1.53e-04 7qdd:B
18 8xxm:3G 84 83 0.2529 0.2619 0.2651 1.88e-04 5k0y:O, 8pj1:o, 8pj2:o, 8pj3:o, 8pj4:o, 8pj5:o, 8pj6:o
19 2mkc:A 118 82 0.2299 0.1695 0.2439 4.37e-04 2my3:A
20 7dco:X 128 82 0.2299 0.1562 0.2439 5.28e-04 5gm6:V, 5zwm:X
21 8i0v:4 161 86 0.2529 0.1366 0.2558 5.29e-04
22 8i0v:4 161 80 0.2759 0.1491 0.3000 0.001
23 8y6o:W 167 71 0.2529 0.1317 0.3099 6.57e-04
24 6r5k:H 394 65 0.2759 0.0609 0.3692 0.001 6r5k:D, 6r5k:F
25 6dg0:B 84 82 0.2759 0.2857 0.2927 0.001 6dg0:A
26 7csz:A 175 64 0.2759 0.1371 0.3750 0.002
27 8h6e:4R 106 74 0.2299 0.1887 0.2703 0.005 8h6j:4R, 8qp8:R, 8qp9:R, 8qpk:R, 6qw6:R, 6qx9:R, 8qxd:R, 8r08:R, 8r0a:R
28 2yka:A 124 84 0.2414 0.1694 0.2500 0.006
29 4lmz:A 176 64 0.2184 0.1080 0.2969 0.007 3nmr:A, 3nna:A, 3nnc:A, 3nnh:A, 3nnh:C, 3nnh:B, 3nnh:D
30 4qqb:A 169 77 0.2299 0.1183 0.2597 0.008 1b7f:A, 1b7f:B, 4qqb:B
31 4a8x:A 88 67 0.2414 0.2386 0.3134 0.009
32 4bs2:A 174 50 0.1609 0.0805 0.2800 0.027 4iuf:A, 4y00:A, 4y00:B, 4y00:C, 4y00:D, 4y0f:A, 4y0f:B
33 8pv1:CI 152 65 0.2529 0.1447 0.3385 0.033 8i9p:CI, 8i9r:CI, 8i9t:CI, 8i9v:CI, 8i9w:CI, 8i9x:CI, 8i9y:CI, 8i9z:CI, 8ia0:CI, 8pv3:CI, 8pv4:CI, 8pv7:CI, 8pvk:CI
34 6g90:B 193 68 0.2414 0.1088 0.3088 0.034
35 6n7p:A 186 68 0.2414 0.1129 0.3088 0.070 6n7r:A, 6n7x:A, 7oqc:B, 7oqe:B, 8w2o:A, 5zwn:Q
36 2n82:B 104 46 0.1724 0.1442 0.3261 0.082 2err:A, 7vrl:B
37 6g90:A 99 52 0.1954 0.1717 0.3269 0.12
38 8esq:o 137 67 0.2069 0.1314 0.2687 0.13 8esr:o, 8etg:o, 8eth:o, 8eti:o, 8eup:o, 8euy:o, 8ev3:o
39 7dvq:Y 140 59 0.1609 0.1000 0.2373 0.13 8i0p:Y, 8i0r:Y
40 8pj1:1 588 53 0.1724 0.0255 0.2830 0.14 6fec:w, 2krb:A, 8oz0:I, 8pj2:1, 8pj3:1, 8pj5:1, 8pj6:1
41 8xxn:3B 536 53 0.1724 0.0280 0.2830 0.16 6zon:B, 6zp4:B, 6zvj:B
42 1fje:B 175 78 0.2759 0.1371 0.3077 0.17 1rkj:A
43 3s1s:A 870 52 0.1839 0.0184 0.3077 0.34
44 8fkp:SH 150 60 0.1839 0.1067 0.2667 0.50 8fkq:SH, 8fkr:SH, 8fks:SH, 8fkt:SH, 8fku:SH, 8fkv:SH, 8fkw:SH, 8fkx:SH, 8fky:SH, 8fkz:SH, 8fl2:SH, 8fl6:SH, 8fla:SH, 8fld:SH, 8ine:t, 8inf:t, 8ipx:t, 8ipy:t, 8ir3:t
45 8ro0:O 342 49 0.2069 0.0526 0.3673 0.50 8ro1:O
46 2rs2:A 84 61 0.1839 0.1905 0.2623 0.67
47 2adb:A 127 64 0.2299 0.1575 0.3125 0.99 3zzy:A, 3zzy:B, 3zzz:A, 3zzz:B
48 3cei:A 213 29 0.1494 0.0610 0.4483 1.4 3cei:B
49 3d34:B 215 27 0.1149 0.0465 0.3704 1.6 3d34:A
50 5det:B 94 87 0.2644 0.2447 0.2644 1.8 5det:A
51 6n7r:C 133 58 0.2069 0.1353 0.3103 2.3 6n7p:C, 6n7x:C, 7oqc:A, 7oqe:A, 8w2o:C, 5zwn:S
52 3zxk:A 530 32 0.1264 0.0208 0.3438 2.4 3zxk:B
53 4dtf:A 356 54 0.1954 0.0478 0.3148 3.3 4dth:A, 4dtl:A, 4e1c:A, 4e1d:A, 4e1f:A, 4gqk:A
54 1gud:A 288 18 0.1264 0.0382 0.6111 4.6 1rpj:A, 8wl7:A, 8wl9:A, 8wlb:A
55 6xyw:Aj 155 75 0.2299 0.1290 0.2667 5.4
56 8hg5:Q 225 29 0.1264 0.0489 0.3793 6.5 7yca:Q
57 2o0r:A 385 45 0.1494 0.0338 0.2889 8.2 2o0r:B
58 5es1:A 304 45 0.1494 0.0428 0.2889 9.1
59 7xyf:K 656 22 0.1379 0.0183 0.5455 10.0 7xyg:K

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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