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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDI
KAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQ
AVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARG
GLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESL
RNCVNKE

The query sequence (length=327) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ati:A 330 327 1.0000 0.9909 1.0000 0.0 8ati:B, 8ati:C, 8ati:D, 4lcj:A, 4lcj:B, 4lcj:C, 4lcj:D, 4lcj:E, 4lcj:F, 4lcj:G, 4lcj:H, 2ome:A, 2ome:B, 2ome:C, 2ome:D, 2ome:E, 2ome:F, 2ome:G, 2ome:H, 6wkw:D, 6wkw:C, 6wkw:B, 6wkw:A
2 6cdf:A 333 327 0.8838 0.8679 0.8838 0.0 8ari:A, 8ari:G, 8ari:D, 8ari:F, 8ari:E, 8ari:J, 8ari:H, 8ari:K, 8ari:I, 8ari:P, 8ari:L, 8ari:M, 8ari:N, 8ari:T, 8ari:O, 8ari:Q, 8ari:R, 8ari:U, 8ari:S, 8ari:X, 8ari:B, 8ari:C, 8ari:V, 8ari:W, 6cdr:A, 1hku:A, 1hl3:A, 2hu2:A, 7kwm:A, 4lce:A, 1mx3:A, 4u6q:A, 4u6s:A, 6v89:A, 6v8a:A
3 5aov:A 334 284 0.3058 0.2994 0.3521 1.14e-41
4 1wwk:A 304 256 0.2905 0.3125 0.3711 3.61e-40 1wwk:B
5 3dc2:A 526 314 0.3089 0.1920 0.3217 4.52e-39 3dc2:B, 3ddn:B
6 3kb6:B 334 322 0.3028 0.2964 0.3075 7.52e-38 3kb6:A, 3kb6:C, 3kb6:D
7 7dkm:A 306 268 0.2691 0.2876 0.3284 9.37e-38 7cvp:B, 6cwa:A, 6cwa:B, 7dkm:B, 7ewh:A, 7ewh:B, 2g76:A, 2g76:B, 5n53:B, 5n53:A, 5n6c:A, 5n6c:B, 5nzo:B, 5nzo:A, 5nzp:B, 5nzp:A, 5nzq:B, 5nzq:A, 5ofm:B, 5ofm:A, 5ofv:B, 5ofv:A, 5ofw:B, 5ofw:A, 6plf:A, 6plf:B, 6plg:A, 6plg:B, 6plg:C, 6plg:D, 6plg:E, 6plg:F, 6plg:G, 6plg:H, 6rih:A, 6rih:B, 6rj2:A, 6rj2:B, 6rj3:A, 6rj3:B, 6rj5:A, 6rj5:B, 6rj6:A, 6rj6:B, 7va1:B, 7va1:A, 7va1:C, 7va1:D
8 6bii:A 332 275 0.2875 0.2831 0.3418 3.97e-36 6bii:B
9 2dbq:A 333 284 0.2966 0.2913 0.3415 3.16e-33 2dbr:A, 2dbr:B, 2dbr:C, 2dbr:D, 2dbr:E, 2dbr:F, 2dbz:A, 2dbz:B
10 4cuk:A 330 258 0.2538 0.2515 0.3217 4.02e-33 4cuk:D
11 5z20:F 336 257 0.2691 0.2619 0.3424 5.44e-32 5z20:A, 5z20:B, 5z20:C, 5z20:D, 5z20:E
12 2w2l:A 346 208 0.2171 0.2052 0.3413 1.04e-31 2w2l:B, 2w2l:C, 2w2l:D
13 2dld:A 337 311 0.2661 0.2582 0.2797 1.22e-31 2dld:B
14 7cvp:A 254 229 0.2294 0.2953 0.3275 3.58e-30
15 1dxy:A 330 256 0.2416 0.2394 0.3086 4.64e-30
16 1j49:A 332 239 0.2294 0.2259 0.3138 9.36e-30 1j49:B
17 4zgs:A 346 242 0.2385 0.2254 0.3223 1.51e-29 4zgs:B, 4zgs:C, 4zgs:D, 4zgs:E, 4zgs:F, 4zgs:G, 4zgs:H
18 7arz:A 361 244 0.2324 0.2105 0.3115 1.72e-29
19 8grv:A 336 278 0.2355 0.2292 0.2770 2.05e-28
20 6ttb:A 331 265 0.2294 0.2266 0.2830 6.33e-28
21 2p9e:A 406 259 0.2477 0.1995 0.3127 3.89e-27 2p9c:A, 2p9c:B, 2p9e:B, 2p9e:C, 2p9e:D, 2p9g:A, 2p9g:B, 2pa3:A, 1psd:A, 1psd:B, 1sc6:A, 1sc6:B, 1yba:A, 1yba:B, 1yba:C, 1yba:D
22 5v6q:B 319 247 0.2538 0.2602 0.3360 1.24e-26 5j23:A, 5j23:B, 5j23:C, 5j23:D, 5v6q:A, 5v6q:C, 5v6q:D, 5v7g:A, 5v7g:B, 5v7g:C, 5v7g:D, 5v7n:A, 5v7n:B, 5v7n:C, 5v7n:D
23 2yq5:C 331 263 0.2416 0.2387 0.3004 1.14e-25 2yq5:A, 2yq5:B, 2yq5:D
24 6ih6:A 330 267 0.2630 0.2606 0.3221 2.12e-25 6ih3:A, 6ih5:B, 6ih6:B
25 3wr5:A 401 291 0.2630 0.2145 0.2955 3.00e-25 6juj:A, 6juj:B, 6juk:A, 6juk:B, 2nad:A, 2nad:B, 8oq2:A, 8oq2:B, 8oq2:C, 8oq2:D, 8oq2:E, 8oq2:F, 3wr5:B, 3wr5:C
26 1sc6:D 384 250 0.2569 0.2188 0.3360 5.65e-25 1sc6:C
27 2gsd:A 399 280 0.2385 0.1955 0.2786 6.95e-25
28 2ekl:A 312 217 0.1957 0.2051 0.2949 1.19e-24
29 6t9w:B 383 286 0.2446 0.2089 0.2797 2.28e-24 8bxx:AA, 8bxx:BB, 8bxx:CC, 8bxx:DD, 6t9w:A, 6t9w:C, 6t9x:B, 6t9x:A, 6t9x:C, 6t9x:D, 6tb6:B
30 6t8y:BBB 375 285 0.2630 0.2293 0.3018 3.59e-24 6t8y:AAA, 6t8y:CCC, 6t8y:DDD, 6t8z:AAA, 6t8z:BBB, 6t8z:CCC, 6t8z:DDD, 6t92:AAA, 6t92:BBB, 6t92:CCC, 6t92:DDD, 6t94:AAA, 6t94:BBB, 6t94:CCC, 6t94:DDD
31 3jtm:A 351 260 0.2232 0.2080 0.2808 6.40e-24 3n7u:A, 3n7u:B, 3n7u:C, 3n7u:D, 3n7u:E, 3n7u:F, 3n7u:G, 3n7u:H, 3n7u:I, 3n7u:J, 3n7u:K, 3n7u:L
32 6d4b:A 361 277 0.2263 0.2050 0.2671 2.80e-23 6d4b:B, 6d4c:A, 6d4c:B, 5dn9:A, 5dn9:B
33 4e5p:A 332 306 0.2752 0.2711 0.2941 3.68e-23 4e5k:A, 4e5k:B, 4e5k:C, 4e5k:D, 4e5m:A, 4e5m:B, 4e5n:A, 4e5n:B, 4e5n:C, 4e5n:D, 4e5n:E, 4e5n:F, 4e5n:G, 4e5n:H, 4e5p:B, 4e5p:C, 4e5p:D, 4e5p:E, 4e5p:F, 4ebf:A, 4ebf:B, 4ebf:C, 4ebf:D, 4nu5:A, 4nu5:B, 4nu6:A, 4nu6:B
34 5z21:B 331 320 0.2661 0.2628 0.2719 7.82e-23 5z21:A, 5z21:C, 5z21:D
35 6p2i:A 307 276 0.2477 0.2638 0.2935 1.40e-22 6p2i:B
36 4prl:A 330 240 0.2232 0.2212 0.3042 2.28e-22 4prl:B
37 3baz:A 311 253 0.2294 0.2412 0.2964 3.24e-22
38 4xkj:A 332 268 0.2661 0.2620 0.3246 1.36e-21 4xkj:B
39 8j3p:A 374 218 0.1957 0.1711 0.2936 7.15e-21 8j3o:A, 8j3o:B, 8j3o:C, 8j3o:D, 8j3p:B, 8j3p:C
40 2gcg:A 324 258 0.2141 0.2160 0.2713 5.01e-20 2gcg:B, 2gcg:C, 2gcg:D
41 7ya3:B 384 220 0.1774 0.1510 0.2636 1.17e-19 7ya3:A, 7ya4:A, 7ya4:B
42 4xyb:A 384 301 0.2691 0.2292 0.2924 2.93e-19 4xyb:B, 4xye:A, 4xye:B
43 5dt9:A 379 151 0.1682 0.1451 0.3642 1.53e-15
44 4njm:A 303 190 0.1498 0.1617 0.2579 2.88e-15 4njm:B, 4njo:A
45 5mh5:A 308 243 0.2141 0.2273 0.2881 4.35e-15 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
46 2o4c:A 380 140 0.1590 0.1368 0.3714 3.55e-14 2o4c:B
47 5vg6:B 315 257 0.2110 0.2190 0.2685 1.01e-13 5vg6:A, 5vg6:C, 5vg6:D, 5vg6:E, 5vg6:F, 5vg6:G, 5vg6:H, 5vg6:I, 5vg6:J
48 3kbo:A 312 237 0.1957 0.2051 0.2700 4.90e-13 3kbo:B, 3kbo:C, 3kbo:D
49 3oet:H 378 261 0.1957 0.1693 0.2452 1.09e-12 3oet:A, 3oet:B, 3oet:C, 3oet:D, 3oet:E, 3oet:F, 3oet:G
50 4zqb:B 316 207 0.1957 0.2025 0.3092 1.32e-11 4zqb:A
51 5bqf:A 317 260 0.2080 0.2145 0.2615 4.60e-11 5tsd:A, 5tsd:B, 4xcv:A
52 7jqh:A 313 238 0.1804 0.1885 0.2479 9.42e-11 7jqi:A, 7jqj:A, 6ovl:A, 6oxn:A, 6p35:A
53 4weq:A 316 249 0.1988 0.2057 0.2610 5.46e-10 4z0p:A
54 7o5l:A 417 146 0.1131 0.0887 0.2534 3.70e-04 7o5l:C, 7o5m:A, 7o5m:C, 7zd7:A, 7zd7:C, 7zd8:A, 7zd8:C, 7zd9:A, 7zd9:C
55 1qp8:A 301 276 0.1896 0.2060 0.2246 0.001 1qp8:B
56 5azf:A 119 32 0.0428 0.1176 0.4375 0.066 5azf:B, 5azg:A, 5azg:B, 8tgf:A
57 4hnx:A 713 99 0.0856 0.0393 0.2828 0.43
58 4xnh:A 786 76 0.0612 0.0254 0.2632 1.1 4hnw:A, 6o07:A, 4xpd:A, 4y49:G
59 4xg1:B 418 83 0.0734 0.0574 0.2892 1.3 4xg1:C, 4xg1:D
60 8a1z:A 396 40 0.0489 0.0404 0.4000 1.6 8a21:A, 5is2:A, 5it0:A, 5it4:A, 5jjb:A, 5jlp:A, 5jlr:A, 5jma:A, 3p96:A, 5t41:A
61 3ss7:X 437 41 0.0428 0.0320 0.3415 1.7 3ss9:X
62 5h81:B 354 49 0.0581 0.0537 0.3878 1.9 5h81:A, 5h82:A, 5h82:B
63 2i9p:B 296 92 0.0642 0.0709 0.2283 2.0 2i9p:A, 2i9p:C, 2i9p:D
64 6vpb:B 324 28 0.0367 0.0370 0.4286 2.4
65 6hd7:t 838 79 0.0673 0.0263 0.2785 3.8
66 8qno:A 421 30 0.0336 0.0261 0.3667 4.5 8qno:B, 7r37:A, 7r37:B, 7r38:A, 7r38:B
67 6jcz:C 331 71 0.0581 0.0574 0.2676 5.5 6jcw:A, 6jcw:B, 6jcw:C, 6jcw:D, 6jcw:E, 6jcw:F, 6jcw:G, 6jcw:H, 6jcw:I, 6jcw:J, 6jcw:K, 6jcw:L, 6jcz:A, 6jcz:B, 6jcz:D, 6jcz:E, 6jcz:F, 6jcz:G, 6jcz:H, 6jcz:I, 6jcz:J, 6jcz:K, 6jcz:L, 6jd1:A, 6jd1:B, 6jd1:C, 6jd1:D, 6jd1:E, 6jd1:F, 6jd1:G, 6jd1:H, 6jd1:I, 6jd1:J, 6jd1:K, 6jd1:L, 6jd2:A, 6jd2:B, 6jd2:C, 6jd2:D, 6jd2:E, 6jd2:F, 6jd2:G, 6jd2:H, 6jd2:I, 6jd2:J, 6jd2:K, 6jd2:L, 6kou:A, 6kou:B, 6kou:C, 6kou:D, 6kou:E, 6kou:F, 6kou:G, 6kou:H, 6kou:I, 6kou:J, 6kou:K, 6kou:L, 6kpa:A, 6kpa:B, 6kpa:C, 6kpa:D, 6kpa:E, 6kpa:F, 6kpa:G, 6kpa:H, 6kpa:I, 6kpa:J, 6kpa:K, 6kpa:L, 6kph:A, 6kph:B, 6kph:C, 6kph:D, 6kph:E, 6kph:F, 6kph:G, 6kph:H, 6kph:I, 6kph:J, 6kph:K, 6kph:L, 6kpi:A, 6kpi:B, 6kpi:C, 6kpi:D, 6kpi:E, 6kpi:F, 6kpi:G, 6kpi:H, 6kpi:I, 6kpi:J, 6kpi:K, 6kpi:L, 6kpj:A, 6kpj:B, 6kpj:C, 6kpj:D, 6kpj:E, 6kpj:F, 6kpj:G, 6kpj:H, 6kpj:I, 6kpj:J, 6kpj:K, 6kpj:L, 6kq4:A, 6kq4:B, 6kq4:C, 6kq4:D, 6kq4:E, 6kq4:F, 6kq4:G, 6kq4:H, 6kq4:I, 6kq4:J, 6kq4:K, 6kq4:L, 6kqj:A, 6kqj:B, 6kqj:C, 6kqj:D, 6kqj:E, 6kqj:F, 6kqj:G, 6kqj:H, 6kqj:I, 6kqj:J, 6kqj:K, 6kqj:L, 6kqk:A, 6kqk:B, 6kqk:C, 6kqk:D, 6kqk:E, 6kqk:F, 6kqk:G, 6kqk:H, 6kqk:I, 6kqk:J, 6kqk:K, 6kqk:L, 6kqo:A, 6kqo:B, 6kqo:C, 6kqo:D, 6kqo:E, 6kqo:F, 6kqo:G, 6kqo:H, 6kqo:I, 6kqo:J, 6kqo:K, 6kqo:L
68 1xvl:A 279 54 0.0581 0.0681 0.3519 6.6 4irm:A, 4irm:B, 3ujp:A, 3ujp:B, 3ujp:C, 1xvl:B
69 6ofu:B 264 84 0.0673 0.0833 0.2619 6.9 6ofu:A, 6ofu:C, 6ofu:D
70 6ln0:A 425 43 0.0459 0.0353 0.3488 9.3
71 5e4r:A 466 97 0.0765 0.0536 0.2577 9.7 4xdz:A, 4xdz:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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