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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PLSLPLDLAPGLVDGDTFLSIMGALPTGVTVVTTLGPDGEPYGLTCSAACSVSKAPPLLLVCINRDSRVLKALLERGEFA
VNVLRGGGESTSARFAAPVDDRFRDVRWEPGSAGGVPVMSADVVAHAECRVAAALDAGDHTIVIGAVVAGGPRPEVPSPL
MYWRRSYARW

The query sequence (length=170) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ct0:H 178 170 1.0000 0.9551 1.0000 5.37e-120 8ct0:A, 8ct0:B, 8ct0:C, 8ct0:G, 8ct0:D, 8ct0:E, 8ct0:F
2 4l82:B 167 159 0.3059 0.3114 0.3270 1.18e-29 4l82:A
3 3rh7:A 292 128 0.3471 0.2021 0.4609 2.39e-27 3rh7:C, 3rh7:D, 3rh7:F
4 3k87:A 164 155 0.3529 0.3659 0.3871 2.09e-23 3k87:B, 3k88:A, 3k88:B
5 1rz0:A 153 162 0.3176 0.3529 0.3333 1.04e-22 1rz0:B, 1rz0:C, 1rz0:D, 1rz0:E, 1rz0:F, 1rz0:G, 1rz0:H, 1rz1:A, 1rz1:B, 1rz1:C, 1rz1:D, 1rz1:E, 1rz1:F, 1rz1:G, 1rz1:H
6 4r82:A 166 109 0.2529 0.2590 0.3945 6.17e-20 4r82:B
7 3cb0:A 166 161 0.3059 0.3133 0.3230 7.32e-20 3cb0:B, 4ira:A
8 2d38:A 156 151 0.3000 0.3269 0.3377 2.58e-19 2d36:A, 2d37:A
9 5zyr:A 306 157 0.2941 0.1634 0.3185 2.98e-18 5zc2:B, 5zc2:A, 5zyr:B
10 4xj2:A 162 132 0.3118 0.3272 0.4015 1.99e-14
11 2ed4:A 149 160 0.3059 0.3490 0.3250 2.67e-13 2ed4:B
12 5cho:A 165 126 0.2471 0.2545 0.3333 1.10e-11 5cho:C, 5cho:B, 5cho:D, 5cho:E, 5cho:F, 5cho:G, 5cho:H
13 4f07:F 155 153 0.2529 0.2774 0.2810 3.72e-11 4f07:A, 4f07:B, 4f07:C, 4f07:G, 4f07:D, 4f07:E, 4f07:H, 4f07:I, 4f07:J, 4f07:L, 4f07:K
14 1i0r:A 161 133 0.2059 0.2174 0.2632 7.55e-08 1i0s:A
15 3pft:B 157 149 0.2588 0.2803 0.2953 6.08e-07 3pft:A
16 1yoa:A 159 148 0.2588 0.2767 0.2973 5.30e-05
17 2r6v:A 182 39 0.0941 0.0879 0.4103 0.23 3zoc:A, 3zod:A, 3zog:A
18 2d5m:A 183 60 0.0882 0.0820 0.2500 0.72
19 1eje:A 192 144 0.1765 0.1562 0.2083 1.0
20 7r81:G2 202 73 0.1118 0.0941 0.2603 1.2 7olc:SF, 7old:SF, 8oo0:SF, 5oql:n, 6rxt:Cc, 6rxu:Cc, 6rxv:Cc, 6rxx:Cc, 6rxy:Cc, 6rxz:Cc, 7z3n:SF, 7z3o:SF
21 3bnk:B 187 101 0.1353 0.1230 0.2277 1.5 3bnk:A
22 8auv:d 194 72 0.0941 0.0825 0.2222 1.5 8b2l:d1, 7qiy:E, 7qiz:OA
23 7uf8:A 341 65 0.1000 0.0499 0.2615 2.8 7uf8:B, 7uf8:C, 7uf8:D
24 6mgr:C 369 151 0.2529 0.1165 0.2848 3.7 6mgr:A, 6mgr:B, 6mgr:D, 4mz1:A, 4mz1:B, 4mz1:C, 4mz8:A, 4mz8:B, 4mz8:C, 4mz8:D, 4r7j:A, 5uqf:A, 5uqf:B, 5uqf:C, 5uqg:A, 5uqg:B, 5uqg:H, 5uqg:C, 5uqg:G, 5uqg:D, 5uqg:E, 5uqg:F, 5uqh:A, 5uqh:B, 5uqh:C, 5uqh:D, 5uqh:E, 5uqh:F, 5uqh:G, 5uqh:H, 5urq:A, 5urq:D, 5urq:B, 5urq:C, 5urq:E, 5urq:H, 5urq:F, 5urq:G
25 7oj2:A 353 158 0.2059 0.0992 0.2215 4.8
26 5xxu:F 187 72 0.1059 0.0963 0.2500 5.5
27 5nv9:A 480 57 0.1059 0.0375 0.3158 8.7 5nva:A
28 3hmz:A 191 59 0.0824 0.0733 0.2373 9.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218