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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PLKVEKFATANRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPD
HKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDRKEGLRQLVMTFQHFMREEIQDA
SQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDM
LMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPD
INIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRV
THGREHSLIEDLILLLEECDANIRAS

The query sequence (length=426) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ex0:A 429 426 1.0000 0.9930 1.0000 0.0 7bj1:A, 5ccl:A, 5ccm:A, 5ex3:A, 5hi7:A, 5hq8:A, 5hq8:B, 6ijl:A, 3mek:A, 7o2a:A, 7o2b:A, 7o2c:A, 6o9o:A, 8owo:A, 3oxf:A, 3oxf:B, 3oxg:A, 3oxl:A, 6p6g:A, 6p6k:A, 6p7z:A, 6paf:A, 3pdn:A, 7qlb:A, 7qnr:A, 7qnu:A, 3qwp:A, 3ru0:A, 3ru0:B, 5v37:A, 5xxd:A, 5xxg:A, 5xxj:A, 5yjo:A, 6yuh:A, 6zrb:A
2 5v3h:A 438 422 0.3169 0.3082 0.3199 1.97e-71 5arf:A, 5arg:A, 6cbx:A, 6cbx:B, 6cby:A, 6cby:B, 5kjk:A, 5kjl:A, 5kjm:A, 5kjn:A, 6mon:A, 6mon:B, 6n3g:A, 4o6f:A, 3qwv:A, 3qww:A, 3rib:A, 3rib:B, 3s7b:A, 3s7d:A, 3s7f:A, 3s7j:A, 3tg4:A, 3tg5:A, 5wcg:A, 4wuy:A, 4ynd:A
3 3n71:A 468 446 0.3239 0.2949 0.3094 1.70e-68
4 6fnd:A 423 89 0.0704 0.0709 0.3371 9.23e-05 6fnd:B, 6fnd:C, 6fnd:D
5 4a24:A 47 39 0.0376 0.3404 0.4103 2.90e-04 2jw6:A
6 8t9f:K 264 117 0.0634 0.1023 0.2308 4.33e-04 4bup:A, 4bup:B, 5cpr:B, 8jhf:K, 8jhg:K, 3s8p:A, 3s8p:B, 5wbv:A, 5wbv:B, 7yrd:K, 7yrg:K
7 7yrg:L 240 73 0.0516 0.0917 0.3014 0.001
8 4au7:A 243 94 0.0540 0.0947 0.2447 0.002 4au7:B, 3rq4:A
9 2dj8:A 60 33 0.0305 0.2167 0.3939 0.008
10 6kiu:K 179 41 0.0469 0.1117 0.4878 0.011 6kiv:K, 6kix:K, 6kiz:K, 7ud5:K
11 2w5z:A 180 41 0.0469 0.1111 0.4878 0.015 5f5e:A, 5f6l:A, 6pwv:C, 6pww:C, 7u5v:A, 6u9k:A, 6u9k:B, 6u9m:A, 6u9m:B, 6u9n:A, 6u9n:B, 6u9r:A, 6u9r:B, 2w5y:A, 7w67:C, 7w6a:C, 7w6i:C, 7w6j:C
12 2od1:A 50 33 0.0305 0.2600 0.3939 0.016 2odd:A
13 9de2:A 71 33 0.0282 0.1690 0.3636 0.021
14 1peg:A 266 59 0.0540 0.0865 0.3898 0.032 1ml9:A, 1peg:B
15 7xpx:K 167 50 0.0516 0.1317 0.4400 0.037 6boz:A, 6boz:B, 2bqz:A, 2bqz:E, 3f9w:B, 3f9w:A, 3f9w:C, 3f9w:D, 3f9x:B, 3f9x:A, 3f9x:C, 3f9x:D, 3f9y:A, 3f9y:B, 3f9z:B, 3f9z:A, 3f9z:C, 3f9z:D, 4ij8:A, 4ij8:B, 5t5g:A, 5teg:A, 5teg:B, 5th7:A, 5th7:B, 5w1y:A, 5w1y:B, 1zkk:A, 1zkk:B, 1zkk:C, 1zkk:D
16 6ven:N 218 41 0.0399 0.0780 0.4146 0.048
17 6ine:A 247 45 0.0446 0.0769 0.4222 0.086 6ago:A, 6ago:B, 3ope:A, 3ope:B, 6wzw:A, 6x0p:A, 6x0p:B, 6x0p:C, 6x0p:D, 4ynm:A, 4ynm:B, 4ynp:A, 4ynp:B, 4ypa:A, 4ypa:B, 4ypa:C, 4ypa:D, 4ype:A, 4ype:B, 4ypu:A, 4ypu:B
18 2r3a:A 270 57 0.0540 0.0852 0.4035 0.092 6p0r:A, 6p0r:B
19 7bre:B 163 41 0.0446 0.1166 0.4634 0.093 7bre:E
20 2g46:A 119 72 0.0493 0.1765 0.2917 0.12 2g46:B, 3kmt:A, 3kmt:B, 3kmt:C
21 8qma:J 426 114 0.0681 0.0681 0.2544 0.17 8r5o:L, 8r6s:L, 8ras:L, 8rdj:L
22 5lsu:A 231 46 0.0516 0.0952 0.4783 0.57 7cro:I, 7e8d:K, 5lsu:B
23 7w6l:C 158 64 0.0540 0.1456 0.3594 0.59 5f59:A, 5f6k:C, 5f6k:E, 6kiw:K, 7w6l:E
24 6cen:A 226 50 0.0516 0.0973 0.4400 0.67 7crp:I, 7crq:L, 7crq:I, 7crr:I, 5upd:A
25 9f2k:A 513 66 0.0399 0.0331 0.2576 0.71
26 6uh5:M 222 41 0.0376 0.0721 0.3902 0.72 6chg:C
27 6ugm:M 188 41 0.0376 0.0851 0.3902 0.78
28 2d8q:A 70 72 0.0516 0.3143 0.3056 0.87 2dan:A
29 7td5:F 447 43 0.0423 0.0403 0.4186 1.0
30 7td5:A 497 43 0.0423 0.0362 0.4186 1.1
31 7kso:A 395 43 0.0423 0.0456 0.4186 1.1 7ksr:A, 7ktp:A
32 5ij7:B 469 43 0.0423 0.0384 0.4186 1.3 6b3w:A, 6b3w:B, 6c23:K, 6c24:K, 5ij7:A, 5ij8:A, 5ij8:B, 4w2r:A, 4w2r:B
33 8tas:E 570 43 0.0423 0.0316 0.4186 1.3 8tb9:E
34 6wkr:C 606 43 0.0423 0.0297 0.4186 1.4 4mi0:A, 4mi5:A, 8t9g:I
35 8t9g:C 536 43 0.0423 0.0336 0.4186 1.5 8fyh:A, 8fyh:G
36 5wg6:A 517 43 0.0423 0.0348 0.4186 1.5 5wg6:C
37 4v6w:CS 173 26 0.0282 0.0694 0.4615 1.6 6xu6:CS, 6xu7:CS, 6xu8:CS
38 5hyn:A 581 43 0.0423 0.0310 0.4186 1.6 5hyn:F, 5hyn:K, 5hyn:Q, 5ls6:A, 5ls6:G, 5ls6:J, 5ls6:D
39 6nzo:S 233 41 0.0376 0.0687 0.3902 1.6 6px3:S
40 9c8u:A 475 43 0.0423 0.0379 0.4186 1.7
41 7x73:A 274 86 0.0610 0.0949 0.3023 1.9 7btv:A, 7btv:B, 7buc:A, 7buc:B, 7dcf:A, 7dcf:B, 5jhn:A, 5jhn:B, 5jin:A, 5jin:B, 5jiy:A, 5jiy:B, 5jj0:A, 5jj0:B, 3k5k:A, 3k5k:B, 4nvq:A, 4nvq:B, 2o8j:A, 2o8j:B, 2o8j:C, 2o8j:D, 3rjw:A, 3rjw:B, 5t0k:A, 5t0k:B, 5t0m:A, 5t0m:B, 7t7l:A, 7t7l:B, 7t7l:C, 7t7l:D, 5ttf:A, 5ttf:B, 5ttf:C, 5ttf:D, 5tuy:A, 5tuy:B, 5v9i:A, 5v9i:B, 5v9i:C, 5v9i:D, 5vsc:A, 5vsc:B, 5vse:A, 5vse:B, 7x73:B, 7xua:A, 7xua:B, 7xub:A, 7xub:B, 7xuc:A, 7xuc:B, 7xud:A, 7xud:B
42 7at8:A 311 43 0.0423 0.0579 0.4186 2.2
43 5kkl:B 839 64 0.0469 0.0238 0.3125 2.3
44 4ccz:A 611 24 0.0282 0.0196 0.5000 2.3
45 5wfd:B 774 64 0.0469 0.0258 0.3125 2.6 5wfc:B
46 5tqr:B 809 64 0.0469 0.0247 0.3125 2.6 5bjs:B, 5vk3:B
47 5kjh:B 807 64 0.0469 0.0248 0.3125 2.7 5m5g:B
48 5wf7:B 765 64 0.0469 0.0261 0.3125 2.8 5kji:B
49 8fbh:A 232 41 0.0376 0.0690 0.3902 3.0 8fbg:A, 8fbg:B, 6kqp:A, 6kqq:A, 6kqq:B, 3ooi:A
50 7krg:F 270 53 0.0352 0.0556 0.2830 4.6 3gdf:A, 3gdf:B, 7krg:A, 7krg:B, 7krg:C, 7krg:D, 7krg:E, 7krg:G, 7krg:H
51 7am2:Aj 342 68 0.0399 0.0497 0.2500 5.7 7aih:Aj, 7ane:Aj
52 5mq4:C 117 32 0.0282 0.1026 0.3750 8.7 5mq4:A, 5mq4:B, 5mq4:D, 5mq4:E, 5mq4:F
53 6a5n:A 502 87 0.0516 0.0438 0.2529 9.5
54 6el3:A 364 73 0.0516 0.0604 0.3014 9.7 6el3:B, 6el3:C, 6el3:D, 6el3:E, 6el3:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218