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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PKWPRQIPYIIASEACERFSFYGMRNILTPFLMTALLLSIPEELRGAVAKDVFHSFVIGVYFFPLLGGWIADRFFGKYNT
ILWLSLIYCVGHAFLAIFEHSVQGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFGSFFASLS
MPLLLKNFGAAVAFGIPGVLMFVATVFFWLGRKRYIHMPPEPKDPHGFLPVIRSALLTKVEGKGNIGLVLALIGGVSAAY
ALVNIPTLGIVAGLCCAMVLVMGFVGAGASLQLERARKSHPDAAVDGVRSVLRILVLFALVTPFWSLFDQKASTWILQAN
DMVKPQWFEPAMMQALNPLLVMLLIPFNNFVLYPAIERMGVKLTALRKMGAGIAITGLSWIVVGTIQLMMDGGSALSIFW
QILPYALLTFGEVLVSATGLEFAYSQAPKAMKGTIMSFWTLSVTVGNLWVLLANVSVKSPTVTEQIVQTGMSVTAFQMFF
FAGFAILAAIVFALYARSYQMQDHY

The query sequence (length=505) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4uvm:A 505 505 1.0000 1.0000 1.0000 0.0
2 6ei3:A 511 505 0.6535 0.6458 0.6535 0.0
3 9bis:A 472 477 0.3188 0.3411 0.3375 3.55e-80 9bir:A, 9bit:A, 9biu:A
4 7pmy:A 657 390 0.2475 0.1903 0.3205 3.45e-55
5 7pmy:A 657 60 0.0614 0.0472 0.5167 8.57e-12
6 7pmx:A 657 409 0.2436 0.1872 0.3007 6.95e-52 7pmw:A
7 7pmx:A 657 100 0.0812 0.0624 0.4100 9.37e-10 7pmw:A
8 6fmr:A 475 448 0.2416 0.2568 0.2723 3.03e-36 4d2b:A, 4d2d:A, 5d58:A, 5d59:A, 6eia:A, 6fmy:A, 6ghj:A, 5oxl:A, 5oxm:A, 5oxn:A, 5oxo:A, 5oxq:A, 4xnj:A, 6yof:A, 6yog:A
9 5oxp:A 462 448 0.2356 0.2576 0.2656 1.47e-29 7ac6:A, 4d2c:A, 5d6k:A, 5oxk:A, 4xni:A
10 4ikz:A 485 451 0.2416 0.2515 0.2705 8.71e-29
11 8qsk:A 523 484 0.2139 0.2065 0.2231 2.68e-27 8qsk:C, 8qsl:A, 8qsl:C, 8wx5:A
12 6gz9:A 488 454 0.2455 0.2541 0.2731 1.45e-26 6exs:A, 6hzp:A
13 6gs4:A 468 451 0.2257 0.2436 0.2528 4.19e-24
14 7q0m:A 482 475 0.2574 0.2697 0.2737 2.23e-23
15 8jzs:B 486 177 0.0950 0.0988 0.2712 2.80e-16 8jzs:A, 8jzu:A, 8wx4:B, 8wx4:A
16 8jzs:B 486 205 0.1050 0.1091 0.2585 4.53e-11 8jzs:A, 8jzu:A, 8wx4:B, 8wx4:A
17 8jzx:A 455 174 0.0931 0.1033 0.2701 7.33e-16 8jzx:B
18 8jzx:A 455 201 0.1010 0.1121 0.2537 2.34e-09 8jzx:B
19 4tpg:A 459 428 0.1921 0.2113 0.2266 1.72e-12 4lep:A, 4lep:B, 4tph:A, 4tpj:B, 4tpj:A
20 5a2o:A 470 194 0.1149 0.1234 0.2990 2.47e-12
21 5a2o:A 470 163 0.0693 0.0745 0.2147 0.11
22 8b17:A 451 446 0.2099 0.2350 0.2377 1.43e-10 8b18:A, 8b19:A, 8b1a:A, 8b1b:A, 8b1c:A, 8b1d:A, 8b1e:A, 8b1f:A, 8b1g:A, 8b1h:A, 8b1i:A, 8b1j:A, 8b1k:A
23 7s3d:F 124 68 0.0416 0.1694 0.3088 4.5 7s3d:Q, 7s3d:f
24 3a7h:B 291 56 0.0396 0.0687 0.3571 9.5 3a7h:A, 3a7i:A, 3a7j:A, 7b30:A, 7b31:A, 7b32:A, 7b33:A, 7b34:A, 7b35:A, 7b35:B, 8bzi:A, 8bzj:A, 8bzj:B, 3ckx:A, 4o27:B, 8qlq:A, 8qlr:B, 8qlr:A, 8qls:A, 8qlt:A, 4qml:A, 4qmm:A, 4qmn:A, 4qmo:A, 4qmp:A, 4qmq:A, 4qms:A, 4qmt:A, 4qmu:A, 4qmv:A, 4qmw:A, 4qmx:A, 4qmy:A, 4qmz:A, 4qna:A, 4qo9:A, 4qo9:B, 4u8z:A, 4w8d:A, 4w8e:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218