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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PKQITDIRKFLKISRKPDTTAVIIMKKKSKTVITKLKLRTKKYLYTMVFADRKKAERIENSLLPSLKRIYYP

The query sequence (length=72) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3j79:d 72 72 1.0000 1.0000 1.0000 4.65e-45 3jbn:Ad, 3jbo:Ad, 3jbp:Ad, 8tpu:Ad, 5umd:d
2 5xxb:j 72 71 0.4583 0.4583 0.4648 2.53e-17
3 8esq:k 70 66 0.4861 0.5000 0.5303 2.23e-16 8esr:k, 8etc:k, 8etg:k, 8eug:k, 8eui:k
4 7r81:m1 73 66 0.4444 0.4384 0.4848 3.53e-14
5 7z3n:Lk 80 67 0.3889 0.3500 0.4179 7.33e-13 8i9x:Lk, 8i9y:Lk, 8i9z:Lk, 8ia0:Lk, 7olc:Lk, 7old:Lk, 8onz:Lk, 8oo0:Lk, 8pv1:Lk, 8pv2:Lk, 8pv3:Lk, 8pv4:Lk, 8pv5:Lk, 8pv6:Lk, 8pv7:Lk, 8pv8:Lk, 8pvk:Lk, 8pvl:Lk, 7z3o:Lk
6 4v8m:Bp 81 69 0.3889 0.3457 0.4058 7.42e-13 8ova:Bp, 8ove:Bp, 5t5h:p
7 6zj3:Lz 70 66 0.4167 0.4286 0.4545 4.75e-12
8 8rxh:Lk 78 69 0.4028 0.3718 0.4203 1.45e-11 8a3w:k, 8a98:k, 6az3:k, 3jcs:k, 8ovj:k, 8rxx:Lk, 5t2a:n
9 9bh5:Ck 69 67 0.3889 0.4058 0.4179 1.72e-10 9cai:Ck
10 4v6w:Ck 70 67 0.3611 0.3714 0.3881 2.29e-10 6xu6:Ck, 6xu7:Ck, 6xu8:Ck
11 7a01:p2 69 66 0.3750 0.3913 0.4091 2.55e-10 8a3d:e, 5aj0:Ak, 8b5l:k, 8b6c:k, 9bdl:AL38, 9bdn:AL38, 9bdp:AL38, 8bf9:k, 7bhp:Lk, 8bhf:X1, 8bpo:j2, 8btk:Bk, 7cpu:Lk, 7cpv:Lk, 4d5y:k, 4d67:k, 6d90:k, 6d9j:k, 9f1b:Bk, 9f1c:Bk, 9f1d:Bk, 7f5s:Lk, 8fkz:LY, 8fl2:LY, 8fl3:LY, 8fl4:LY, 8fl6:LY, 8fl7:LY, 8fl9:LY, 8fla:LY, 8flb:LY, 8flc:LY, 8fld:LY, 8fle:LY, 8flf:LY, 9fpz:Lk, 9fq0:Lk, 6frk:k, 6ftg:k, 6fti:k, 6ftj:k, 8g5y:Lk, 8g5z:Lk, 8g60:Lk, 8g61:Lk, 8g6j:Lk, 8glp:Lk, 6gz3:Ak, 6gz4:Ak, 6gz5:Ak, 6hcf:k3, 6hcj:k3, 6hcm:k3, 6hcq:k3, 8idt:O, 8idy:O, 8ie3:O, 8ifd:2e, 8ife:2e, 8ine:O, 8inf:O, 8ink:O, 6ip5:2e, 6ip6:2e, 6ip8:2e, 8ipd:O, 8ipx:O, 8ipy:O, 8ir1:O, 8ir3:O, 3j7o:k, 3j7p:k, 3j7q:k, 3j7r:k, 3j92:k, 3jag:k, 3jah:k, 3jai:k, 3jaj:k, 3jan:k, 8jdj:p, 8jdk:p, 8jdl:p, 8jdm:p, 8k2c:Lk, 5lks:Lk, 6lqm:O, 6lsr:O, 6lss:O, 7ls1:e2, 7ls2:e2, 6lu8:O, 5lzs:k, 5lzt:k, 5lzu:k, 5lzv:k, 5lzw:k, 5lzx:k, 5lzy:k, 5lzz:k, 7mdz:k, 6mtb:k, 6mtc:k, 6mtd:k, 6mte:k, 7nfx:k, 7nwg:k3, 7nwh:k, 7nwi:k, 7o7y:Bk, 7o7z:Bk, 7o80:Bk, 7o81:Bk, 7obr:k, 8ohd:Lk, 8oj0:Lk, 8oj5:Lk, 8oj8:Lk, 6ole:l, 6olf:l, 6olg:Ak, 6oli:l, 6olz:Ak, 6om0:l, 6om7:l, 8ony:Lk, 7oya:k1, 7oyb:k1, 7oyc:k1, 7oyd:k, 8p2k:Bk, 6p5i:Ak, 6p5j:Ak, 6p5k:Ak, 6p5n:Ak, 8q7z:Bk, 8q87:Bk, 8qfd:k, 7qgg:l, 8qoi:Lk, 7qvp:Lk, 7qvp:Mk, 7qwq:k, 7qwr:k, 7qws:k, 6qzp:Lk, 6r5q:k, 6r6g:k, 6r6p:k, 6r7q:k, 8rjb:k, 8rjc:k, 8rjd:k, 8scb:k, 6sgc:k2, 6swa:i, 6sxo:Lk, 5t2c:e, 6t59:k3, 7tm3:k, 7toq:AL38, 7tor:AL38, 7tut:k, 7ucj:k, 7uck:k, 4ug0:Lk, 4ujc:Bk, 4ujd:Ak, 4uje:Ck, 4v6x:Ck, 6w6l:l, 6xa1:Lk, 7xnx:Lk, 7xny:Lk, 8xsx:Lk, 8xsy:Lk, 8xsz:Lk, 6y0g:Lk, 8y0w:Lk, 8y0x:Lk, 6y2l:Lk, 6y57:Lk, 6y6x:Lk, 8yoo:Lk, 8yop:Lk, 6z6l:Lk, 6z6m:Lk, 6z6n:Lk, 7zjw:Ln, 7zjx:Ln, 6zm7:Lk, 6zme:Lk, 6zmi:Lk, 6zmo:Lk, 6zvk:p2
12 8azw:W 68 66 0.3889 0.4118 0.4242 3.21e-10 8b2l:W3, 7qiw:m, 7qiz:m
13 4v3p:Ln 69 66 0.3889 0.4058 0.4242 6.18e-09 8ip8:NB, 8ipa:NB, 8ipb:NB, 8jiv:Ck, 4v7e:Ck
14 4v8p:AP 66 69 0.4028 0.4394 0.4203 4.79e-08 4v8p:DP, 4v8p:FP, 4v8p:HP
15 4v6i:Bn 78 72 0.4167 0.3846 0.4167 5.90e-08 8aaf:X, 8agt:X, 8agu:X, 8agv:X, 8agw:X, 8agx:X, 8agz:X, 5apn:k, 5apo:k, 7azy:j, 7b7d:Lg, 8bip:Lk, 8bjq:Lk, 8bn3:O8, 8bqd:AI, 8bqx:AI, 7bt6:k, 7btb:k, 6cb1:k, 8ccs:W, 8cdl:W, 8cdr:W, 8ceh:W, 8cf5:W, 8cg8:W, 8cgn:W, 8civ:W, 8cku:W, 8cmj:W, 5dat:O8, 5dat:o8, 5dc3:O8, 5dc3:o8, 5dge:O8, 5dge:o8, 5dgf:O8, 5dgf:o8, 5dgv:O8, 5dgv:o8, 6elz:k, 8eub:Ak, 8evp:Ak, 8evq:Ak, 8evr:Ak, 8evs:Ak, 8evt:Ak, 8ewb:Ak, 8ewc:Ak, 5fci:O8, 5fci:o8, 5fcj:O8, 5fcj:o8, 6ft6:k, 5gak:m, 6gq1:k, 6gqb:k, 6gqv:k, 5h4p:k, 6hd7:m, 8hfr:kr, 6hhq:AL, 6hhq:DM, 5i4l:O8, 5i4l:o8, 6i7o:AI, 6i7o:XI, 3j6x:78, 3j6y:78, 3j77:88, 3j78:88, 3jct:k, 5jcs:k, 5juo:PA, 5jup:PA, 5jus:PA, 5jut:PA, 5juu:PA, 8k2d:Lk, 8k82:Lk, 5lyb:O8, 5lyb:o8, 5m1j:k5, 6m62:k, 5mc6:AI, 5mei:AL, 5mei:DM, 7mpi:Ak, 7mpj:Ak, 6n8j:k, 6n8k:k, 6n8l:k, 6n8m:x, 6n8n:x, 6n8o:x, 7n8b:Ak, 7nac:k, 7nad:k, 5ndg:O8, 5ndg:o8, 5ndv:O8, 5ndv:o8, 5ndw:O8, 5ndw:o8, 7nrc:Lm, 7nrd:Lm, 5obm:O8, 5obm:o8, 7of1:k, 7oh3:k, 7ohq:k, 7ohr:k, 6oig:k, 5on6:AL, 5on6:DM, 7osa:eL38, 7osm:eL38, 8p8m:RM, 8p8n:RM, 8p8u:RM, 8pfr:RM, 6q8y:AI, 6qik:j, 6qt0:j, 6qtz:j, 7r72:k, 7r7a:k, 6r84:m, 6r86:m, 6r87:m, 6ri5:j, 7rr5:Lk, 6rzz:j, 6s05:j, 6s47:Am, 6snt:af, 6sv4:AI, 6sv4:XI, 6sv4:zI, 6t4q:Lk, 5t62:x, 5t6r:x, 6t7i:Lk, 6t7t:Lk, 6t83:kb, 6t83:V, 5tbw:AL, 5tbw:DM, 6tb3:AI, 5tga:O8, 5tga:o8, 5tgm:O8, 5tgm:o8, 6tnu:AI, 7too:AL38, 7top:AL38, 7u0h:k, 4u3m:O8, 4u3m:o8, 4u3n:O8, 4u3n:o8, 4u3u:O8, 4u3u:o8, 4u4n:O8, 4u4n:o8, 4u4o:O8, 4u4o:o8, 4u4q:O8, 4u4q:o8, 4u4r:O8, 4u4r:o8, 4u4u:O8, 4u4u:o8, 4u4y:O8, 4u4y:o8, 4u4z:O8, 4u4z:o8, 4u50:O8, 4u50:o8, 4u51:O8, 4u51:o8, 4u52:O8, 4u52:o8, 4u53:O8, 4u53:o8, 4u55:O8, 4u55:o8, 4u56:O8, 4u56:o8, 4u6f:O8, 4u6f:o8, 7ug6:k, 7uoo:k, 7uqb:k, 7uqz:k, 7v08:k, 4v88:Bk, 4v88:Dk, 4v8t:k, 4v8y:Bk, 4v8z:Bk, 8v87:k, 4v91:k, 6woo:k, 6xiq:k, 6xir:k, 8y0u:Lk, 6ylg:k, 6ylh:k, 6ylx:k, 6yly:k, 7z34:k, 6z6j:Lk, 6z6k:Lk, 7zpq:Bj, 7zrs:Bj, 7zs5:Bl, 7zuw:Bj, 7zux:Ej, 7zw0:Ln
16 5it7:kk 76 71 0.3472 0.3289 0.3521 1.11e-07 6uz7:Bk
17 8c3a:AL 77 75 0.3611 0.3377 0.3467 2.50e-07 8c3a:CF, 8cq7:AL, 8cq7:CF, 8cqw:AL, 8cqw:CF, 8cre:AL, 8cre:CF, 8oeq:AL, 8oeq:CF, 7pzy:AL, 7q08:AL, 7q0f:AL, 7q0p:AL, 7q0r:AL, 8q5i:AL
18 5xy3:k 68 69 0.3889 0.4118 0.4058 8.40e-06
19 7ohv:k 63 67 0.3889 0.4444 0.4179 0.015
20 8fru:k 76 24 0.1806 0.1711 0.5417 0.53 8br8:Ll, 8brm:Ll, 8bsi:Ll, 8bsj:Ll, 8btd:Ll, 8btr:Ll, 7pwg:k, 7pwo:k2
21 5uqd:A 324 24 0.1528 0.0340 0.4583 1.2
22 5k8b:A 394 48 0.2222 0.0406 0.3333 2.3 5k8b:B, 5k8b:C, 5k8b:D
23 2f8s:A 704 50 0.2500 0.0256 0.3600 2.8 2f8t:A
24 6i33:B 925 32 0.2083 0.0162 0.4688 3.3
25 7d4i:SH 182 31 0.1389 0.0549 0.3226 6.6 7d5t:SH, 6lqs:SH, 6lqt:SH
26 8cbj:G 232 31 0.1389 0.0431 0.3226 8.2 7a1g:T, 7ajt:DG, 7aju:DG, 7b7d:T, 8bn3:S6, 8bqd:T, 8bqx:T, 8c00:T, 8c01:T, 8c83:T, 8cah:T, 8cas:T, 8ccs:j, 8cdl:j, 8cdr:j, 8ceh:j, 8cf5:j, 8cg8:j, 8cgn:j, 8civ:j, 8cku:j, 8cmj:j, 5dat:S6, 5dat:s6, 5dc3:S6, 5dc3:s6, 5dge:S6, 5dge:s6, 5dgf:S6, 5dgf:s6, 5dgv:S6, 5dgv:s6, 6eml:T, 8eub:BG, 8evp:BG, 8evq:BG, 8evr:BG, 8evs:BG, 8evt:BG, 8ewb:BG, 8ewc:BG, 6fai:G, 5fci:S6, 5fci:s6, 5fcj:S6, 5fcj:s6, 6gq1:w, 6gqb:w, 6gqv:w, 6hhq:H, 6hhq:s6, 5i4l:S6, 5i4l:s6, 6i7o:T, 6i7o:Tb, 3j16:C, 3j6x:S6, 3j6y:S6, 3j77:S6, 3j78:S6, 5juo:DB, 5jup:DB, 5jus:DB, 5jut:DB, 5juu:DB, 8k2d:SG, 8k82:SG, 5ll6:T, 5lyb:S6, 5lyb:s6, 5m1j:G2, 5mc6:T, 5mei:s6, 5mei:H, 7mpi:BG, 7mpj:BG, 7n8b:BG, 5ndg:S6, 5ndg:s6, 5ndv:s6, 5ndw:S6, 5ndw:s6, 7nrc:ST, 7nrd:ST, 5obm:S6, 5obm:s6, 5on6:s6, 5on6:H, 7osa:eS6, 7osm:eS6, 6q8y:T, 6rbd:G, 6rbe:G, 7rr5:SG, 6s47:BH, 6snt:G, 6sv4:T, 6sv4:Tb, 6sv4:Tc, 6t4q:SG, 6t7i:SG, 6t7t:SG, 6t83:Gb, 6t83:h, 5tbw:H, 5tbw:s6, 6tb3:T, 5tga:S6, 5tga:s6, 5tgm:S6, 5tgm:s6, 6tnu:T, 5tzs:3, 4u3m:S6, 4u3m:s6, 4u3n:S6, 4u3n:s6, 4u3u:S6, 4u3u:s6, 4u4n:S6, 4u4n:s6, 4u4o:S6, 4u4o:s6, 4u4q:S6, 4u4q:s6, 4u4r:S6, 4u4r:s6, 4u4u:S6, 4u4u:s6, 4u4y:S6, 4u4y:s6, 4u4z:S6, 4u4z:s6, 4u50:S6, 4u50:s6, 4u51:S6, 4u51:s6, 4u52:S6, 4u52:s6, 4u53:S6, 4u53:s6, 4u55:S6, 4u55:s6, 4u56:S6, 4u56:s6, 4u6f:S6, 4u6f:s6, 4uer:Y, 4v88:AG, 4v88:CG, 4v8y:AG, 4v8z:AG, 4v92:BG, 6wdr:G, 5wlc:L6, 6woo:GG, 7wtl:SG, 7wtm:SG, 7wtn:SG, 7wto:SG, 7wtp:SG, 7wtq:SG, 7wtr:SG, 6xiq:w, 6xir:w, 8y0u:SG, 6y7c:G, 6z6j:SG, 6z6k:SG, 6zce:H, 7zpq:AG, 6zqb:DG, 6zqc:DG, 6zqd:DG, 6zqe:DG, 6zqf:DG, 6zqg:DG, 7zrs:AG, 6zu9:T, 7zuw:AG, 7zux:DG, 6zvi:o, 7zw0:sT
27 7x53:A 406 38 0.1806 0.0320 0.3421 8.9 7x53:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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