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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PKFDPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEP
SDLICDRPISVLLTSSGTVPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTS
FLKSDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDAT
CTSGIGKFLTAPNPELASLIEQECEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNP
LCKPSDVSYTIIPCMGYFEFLEVPVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLS
IDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSFEPNRDVMEECCFTVEESLDAVYRKGR
KNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSWEL

The query sequence (length=549) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6e1q:A 569 567 0.9964 0.9613 0.9647 0.0 6avh:A, 6avh:C, 6avh:D
2 6avh:B 541 551 0.9709 0.9852 0.9673 0.0
3 5kod:D 566 561 0.5173 0.5018 0.5062 0.0
4 7vka:A 595 581 0.5228 0.4824 0.4940 0.0 5kod:A, 5kod:B, 5kod:C, 7vka:B
5 4epm:A 554 551 0.4991 0.4946 0.4973 0.0 4eq4:A, 4eq4:B, 4eql:A, 4eql:B, 4l39:A, 4l39:B, 6oms:A, 6oms:B
6 7dk8:A 558 556 0.4791 0.4713 0.4730 0.0
7 4b2g:B 572 575 0.4809 0.4615 0.4591 2.31e-176 4b2g:A
8 4ewv:B 492 544 0.4444 0.4959 0.4485 1.69e-157 4ewv:A
9 5ech:A 569 559 0.3734 0.3603 0.3667 7.66e-114 5ech:D, 5eci:A, 5eci:D, 5eck:A, 5eck:D, 5ecl:A, 5ecl:D, 5ecm:A, 5ecm:D, 5ecn:A, 5ecn:D, 5eco:A, 5eco:D, 5ecp:A, 5ecp:D, 5ecq:A, 5ecq:D, 5ecr:A, 5ecr:D, 4epl:A, 5gzz:A
10 8orh:A 649 107 0.0492 0.0416 0.2523 0.79 8orh:B, 8ors:A, 8ors:B, 7yx3:A, 7yx3:B, 4z24:A, 4z24:B, 4z25:A, 4z25:B, 4z25:C, 4z25:D, 4z25:E, 4z25:F, 4z25:G, 4z25:H, 4z25:I, 4z25:J, 4z25:K, 4z25:L, 4z26:A, 4z26:B, 4z26:C, 4z26:D, 4z26:E, 4z26:F, 4z26:G, 4z26:H
11 7c3o:A 316 44 0.0291 0.0506 0.3636 1.7
12 4lt6:A 467 46 0.0255 0.0300 0.3043 2.7 4lt6:B
13 3s6t:A 575 65 0.0328 0.0313 0.2769 4.7 3nsn:A, 3ozo:A, 3ozp:A, 3vtr:A, 3wmb:A, 3wmc:A, 5y0v:A, 5y1b:A
14 5hgc:A 373 117 0.0565 0.0831 0.2650 4.8
15 5kdi:A 211 65 0.0328 0.0853 0.2769 5.0 5kdi:B
16 7mop:A 2445 98 0.0455 0.0102 0.2551 9.4 6fyh:A, 6pfl:A, 6pfl:B, 8r7o:A, 8r7o:C, 8rd0:C, 8rd0:D, 8rd1:A, 8rd1:C, 8rd1:D, 8rd7:D, 6xz1:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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