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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PILTQKNWDGTATYFQSSDEHGFSMYYKPQVGFVGAPMPFYDPVAKDFKVMYLQDYRPNPEATYHPIFGVATKDGATYES
LGELISCGGRDEQDAAIGTGGTIYNPADKLYYTFYTGNKFKPSSDQNAQVVMVATSPDFKTWTKNRTFYLKGDTYGYDKN
DFRDPFLFQTEDGVYHMLIATRKNGKGHIAEFTSADLKEWESAGTFMTMMWDRFYECPDVFKMGDWWYLIYSEQASFMRK
VQYFKGRTLEDLKATTANDAGIWPDNREGMLDSRAFYAGKTASDGTNRYIWGWCPTRAGNDNGNVGDVEPEWAGNLVAQR
LIQHEDGTLTLGVPDAIDRKYTSAQEVKVMAKDGNMIESGKTYTLGEGASVIFNRLKVHNKISFTVKTASNTDRFGISFV
RGTDSASWYSIHVNADEGKANFEKDGDDAKYLFDNKFNIPADNEYRVTIYSDQSVCVTYINDQLSFTNRIYQMQKNPWSL
CCYKGEITVSDVQVSTY

The query sequence (length=497) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8aa2:E 497 497 1.0000 1.0000 1.0000 0.0 8aa2:M, 6r3r:A, 6r3u:A, 7znr:A, 7znr:B, 7zns:A, 7zns:B
2 6s1t:A 512 212 0.1147 0.1113 0.2689 1.05e-07 3kf3:A, 3kf3:B, 6s1t:B, 6s2b:A, 6s2b:B, 3u14:A, 3u14:B, 3u75:A, 3u75:B, 3u75:C, 3u75:D
3 7vcp:A 490 377 0.1670 0.1694 0.2202 1.25e-05
4 7bwc:A 464 240 0.1167 0.1250 0.2417 2.03e-04
5 2ac1:A 537 235 0.1147 0.1061 0.2426 3.21e-04 2oxb:A, 2qqu:A, 2qqv:A, 2qqw:A, 2xqr:A, 2xqr:C, 2xqr:G, 2xqr:K, 2xqr:E, 2xqr:I
6 1w2t:A 432 188 0.1006 0.1157 0.2660 5.97e-04 1w2t:B, 1w2t:C, 1w2t:D, 1w2t:E, 1w2t:F
7 6nun:A 516 402 0.1690 0.1628 0.2090 6.71e-04
8 6nu8:A 488 78 0.0523 0.0533 0.3333 0.001
9 5xha:A 605 161 0.0926 0.0760 0.2857 0.015
10 2add:A 537 221 0.1046 0.0968 0.2353 0.019 2ade:A, 2aey:A, 2aez:A
11 5jab:A 135 66 0.0423 0.1556 0.3182 0.023 2asf:A, 5jab:B, 5jab:C, 5jab:D
12 8beq:A 534 80 0.0483 0.0449 0.3000 0.038 8beq:B, 8bes:A, 8bes:B, 8bes:C, 8bes:D, 8bet:A, 8bet:B, 8bet:C, 8bet:D, 8beu:A, 8beu:B, 8beu:C, 8beu:D
13 6euf:A 472 168 0.0885 0.0932 0.2619 0.062 6euf:B, 6euf:C, 6euf:D
14 4i3g:B 780 147 0.0624 0.0397 0.2109 0.080 4i3g:A
15 1y9g:A 517 128 0.0664 0.0638 0.2578 0.23
16 6m4p:A 378 80 0.0362 0.0476 0.2250 0.92 6m4p:B, 6m4q:A
17 3pij:B 526 386 0.1670 0.1578 0.2150 1.00 3pij:A
18 5mui:A 352 97 0.0584 0.0824 0.2990 1.8 5muj:A
19 3taw:A 349 42 0.0322 0.0458 0.3810 2.8
20 7xld:B 125 85 0.0443 0.1760 0.2588 3.7 7xli:B
21 7rma:A 75 38 0.0282 0.1867 0.3684 7.3
22 2cjw:A 178 58 0.0322 0.0899 0.2759 7.9 2cjw:B, 2g3y:A, 2ht6:A, 2ht6:B
23 5jox:A 502 88 0.0463 0.0458 0.2614 7.9 5jox:B, 5joy:A, 5joy:B
24 7v6i:A 597 66 0.0382 0.0318 0.2879 8.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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