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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANA
IGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQV
AWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHD
IFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGAPAINKMLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVE
KIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGR
ARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQEPGQVWHPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQR
DMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPQGMVGIKFRREKLL
DTMNRLELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIAR
IRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGL

The query sequence (length=675) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5csl:B 2072 697 0.9911 0.3229 0.9598 0.0 5ctb:A, 5ctb:C, 5ctc:A, 5ctc:B, 5ctc:C, 5cte:B, 5cte:C, 3h0s:A, 3k8x:A, 3k8x:B, 3k8x:C, 1od2:A, 1od2:B, 3pgq:A, 3pgq:C, 3tv5:A, 3tv5:B, 3tv5:C, 3tvu:A, 3tvu:B, 3tvu:C, 3tvw:A, 3tvw:B, 3tvw:C, 3tz3:A, 3tz3:B, 3tz3:C, 1w96:A, 1w96:B, 1w96:C, 4wyo:B, 4wyo:C, 4wz8:B, 4wz8:C
2 1uyr:A 698 675 0.9911 0.9585 0.9911 0.0 5ctb:B, 3h0j:A, 3h0j:B, 3h0j:C, 3h0q:A, 3h0q:B, 3h0q:C, 3h0s:B, 3h0s:C, 1od4:C, 3pgq:B, 1uyr:B, 1uys:A, 1uys:B, 1uys:C, 1w2x:A, 1w2x:C, 1w2x:B
3 5csl:A 2050 702 0.9837 0.3239 0.9459 0.0
4 3ff6:A 750 704 0.5467 0.4920 0.5241 0.0 3ff6:B, 3ff6:C, 3ff6:D, 3tdc:A
5 2x24:B 667 649 0.5215 0.5277 0.5424 0.0 2x24:A
6 1vrg:A 515 403 0.1348 0.1767 0.2258 2.55e-12 1vrg:B, 1vrg:C, 1vrg:D, 1vrg:E, 1vrg:F
7 8sgx:E 489 373 0.1230 0.1697 0.2225 1.59e-11 8sgx:F, 8sgx:G, 8sgx:H, 8sgx:C, 8sgy:C, 8sgy:E, 8sgy:G, 8sgy:D, 8sgz:C, 8sgz:D, 8sgz:E, 8sgz:F, 8sgz:G, 8sgz:H
8 7ybu:P 507 361 0.1156 0.1538 0.2161 7.89e-11 7ybu:G, 7ybu:C, 7ybu:K, 7ybu:E, 7ybu:I
9 8pn7:A 506 345 0.1096 0.1462 0.2145 1.45e-08 8pn7:B, 8pn7:C, 8pn7:D, 8pn7:E, 8pn7:F, 8pn8:A, 8pn8:B, 8pn8:C, 8pn8:D, 8pn8:E, 8pn8:F, 6ybp:A, 6ybp:F, 6ybq:A, 6ybq:C, 6ybq:D, 6ybq:E, 6ybq:F
10 1on3:E 520 353 0.1141 0.1481 0.2181 3.86e-07 1on3:A, 1on3:D, 1on3:B, 1on3:C, 1on3:F, 1on9:A, 1on9:B, 1on9:C, 1on9:D, 1on9:E, 1on9:F
11 3ib9:A 521 351 0.1170 0.1516 0.2251 4.40e-07 3ib9:B, 1xny:A, 1xny:B
12 3ib9:A 521 51 0.0252 0.0326 0.3333 7.1 3ib9:B, 1xny:A, 1xny:B
13 3n6r:B 506 308 0.0933 0.1245 0.2045 4.79e-07 3n6r:D, 3n6r:F, 3n6r:H, 3n6r:J, 3n6r:L
14 2f9i:B 260 85 0.0400 0.1038 0.3176 0.001 2f9i:D, 5kdr:B
15 8j4z:J 541 182 0.0711 0.0887 0.2637 0.013 8j4z:H, 8j4z:A, 8j4z:K, 8j4z:C, 8j4z:F, 8j78:J, 8j78:F, 8j78:D, 8j7d:C, 8j7d:G, 8j7d:J, 8j7d:E, 8jaw:B, 8jaw:D, 8jaw:I, 8jaw:G, 8jaw:J, 8jaw:L, 8jxl:B, 8jxl:A, 8jxl:D, 8jxl:K, 8jxl:G, 8jxl:I, 8jxm:K, 8jxm:A, 8jxm:E, 8jxm:J, 8jxn:K, 8jxn:G, 8jxn:I, 8jxn:A, 8k2v:H, 8k2v:I, 8k2v:J, 8k2v:G, 8k2v:K, 8k2v:L
16 8j4z:J 541 59 0.0252 0.0314 0.2881 2.3 8j4z:H, 8j4z:A, 8j4z:K, 8j4z:C, 8j4z:F, 8j78:J, 8j78:F, 8j78:D, 8j7d:C, 8j7d:G, 8j7d:J, 8j7d:E, 8jaw:B, 8jaw:D, 8jaw:I, 8jaw:G, 8jaw:J, 8jaw:L, 8jxl:B, 8jxl:A, 8jxl:D, 8jxl:K, 8jxl:G, 8jxl:I, 8jxm:K, 8jxm:A, 8jxm:E, 8jxm:J, 8jxn:K, 8jxn:G, 8jxn:I, 8jxn:A, 8k2v:H, 8k2v:I, 8k2v:J, 8k2v:G, 8k2v:K, 8k2v:L
17 8rth:F 542 60 0.0281 0.0351 0.3167 0.033 8rth:B, 8rth:D, 8rth:L, 8rth:H, 8rth:J
18 8rth:F 542 283 0.0963 0.1199 0.2297 0.085 8rth:B, 8rth:D, 8rth:L, 8rth:H, 8rth:J
19 4g2r:B 441 266 0.0800 0.1224 0.2030 0.059 4g2r:A, 6p7u:A, 6p7u:B, 6p7u:D, 6pk2:A, 6pk2:B, 6pk2:D, 6pk2:E, 6pk2:F, 6pk2:H, 6prw:A, 6prw:B, 6prw:D, 6prw:E, 6prw:F, 6prw:H, 6tzv:A, 6tzv:B, 6tzv:D, 6tzv:E, 6tzv:F, 6tzv:H
20 6cu5:A 314 63 0.0341 0.0732 0.3651 0.080 6cu5:B, 8ft7:A, 8ft7:B
21 6p7u:C 410 256 0.0756 0.1244 0.1992 0.21 6pk2:C, 6pk2:G, 6prw:C, 6prw:G, 6tzv:C, 6tzv:G
22 3gma:B 566 144 0.0533 0.0636 0.2500 0.35 3gf3:A, 3glm:A, 3glm:C, 3glm:B, 3glm:D, 3gma:A
23 8f3d:A 566 59 0.0252 0.0300 0.2881 0.48 8f3d:B, 8f3d:C, 8f3d:D, 8f3d:E, 8f3d:F, 8f41:B, 8f41:D, 8f41:F, 8f41:A, 8f41:C, 8f41:E
24 5ini:F 511 349 0.1007 0.1331 0.1948 0.49 5inf:B, 5inf:F, 5ini:A, 5ini:D, 5ini:B, 5ini:C, 5ini:E
25 5ini:F 511 51 0.0267 0.0352 0.3529 3.4 5inf:B, 5inf:F, 5ini:A, 5ini:D, 5ini:B, 5ini:C, 5ini:E
26 8jxm:C 520 59 0.0252 0.0327 0.2881 2.3 8j99:B, 8j99:D, 8j99:J, 8j99:G, 8j99:H, 8j99:L, 8jxm:H, 8jxn:D, 8jxn:B
27 3u9s:F 537 59 0.0252 0.0317 0.2881 2.7 3u9s:B, 3u9s:L, 3u9s:D, 3u9s:H, 3u9s:J
28 5z19:B 601 100 0.0341 0.0383 0.2300 5.0 6jz2:A, 6jz2:B, 6jz3:A, 6jz3:B, 6jz4:B, 6jz6:A, 6jz6:B, 6jz8:A, 5z19:A, 5z19:C, 5z19:D, 5z19:E, 5z19:F
29 6jz4:A 576 99 0.0341 0.0399 0.2323 5.0 6jz5:A, 6jz5:B, 6jz7:A, 6jz7:B, 6jz8:B
30 1uf9:B 191 57 0.0296 0.1047 0.3509 6.3 1uf9:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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