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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PHSWGKKARTRDLFSKGFRCHGRPSLSTYLAVFKIGDYVDVVTDPSVQKGQPSKVFQGKTGTVWNVTPRAVGVLVNKRVR
GRIVRKKISVRTEHVRKSRCQQDFKERVRHNELVKRTGVGKKIKRQPVGPREGQLLKLRKKPIPLGAKKFVFSEVYNF

The query sequence (length=158) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6zj3:Lh 158 158 1.0000 1.0000 1.0000 3.57e-113
2 4v8m:BU 158 111 0.4304 0.4304 0.6126 5.09e-43 8ova:BU, 8ove:BU
3 8azw:J 163 141 0.4494 0.4356 0.5035 5.47e-43 8b2l:J3, 7qiw:V, 7qiz:V
4 5t5h:U 126 106 0.4304 0.5397 0.6415 9.50e-43
5 5xxb:S 154 138 0.4684 0.4805 0.5362 1.20e-42
6 4v6w:CT 158 155 0.4620 0.4620 0.4710 5.47e-42 6xu6:CT, 6xu7:CT, 6xu8:CT
7 8rxh:LS 158 106 0.4114 0.4114 0.6132 5.84e-42 8a3w:S, 8a98:S, 6az3:S, 3jcs:S, 8ovj:S, 8rxx:LS, 5t2a:S
8 8eui:T 159 154 0.4620 0.4591 0.4740 1.10e-41 8eug:T
9 8hfr:Tl 160 138 0.4114 0.4062 0.4710 1.39e-41 8aaf:G, 8agt:G, 8agu:G, 8agv:G, 8agw:G, 8agx:G, 8agz:G, 5apn:T, 5apo:T, 7azy:u, 7b7d:Lp, 8bip:LT, 8bjq:LT, 8bn3:N1, 8bqd:BJ, 8bqx:BJ, 7bt6:T, 7btb:T, 8ccs:F, 8cdl:F, 8cdr:F, 8ceh:F, 8cf5:F, 8cg8:F, 8cgn:F, 8civ:F, 8cku:F, 8cmj:F, 5dat:N1, 5dat:n1, 5dc3:N1, 5dc3:n1, 5dge:N1, 5dge:n1, 5dgf:N1, 5dgf:n1, 5dgv:N1, 5dgv:n1, 6elz:T, 8eub:AT, 8evp:AT, 8evq:AT, 8evr:AT, 8evs:AT, 8evt:AT, 8ewb:AT, 8ewc:AT, 5fci:N1, 5fci:n1, 5fcj:N1, 5fcj:n1, 6ft6:T, 5gak:V, 6gq1:T, 6gqb:T, 6gqv:T, 5h4p:T, 6hd7:V, 6hhq:2, 6hhq:CV, 5i4l:N1, 5i4l:n1, 6i7o:BJ, 6i7o:YJ, 5it7:TT, 3j6x:61, 3j6y:61, 3j77:71, 3j78:71, 3jct:T, 5jcs:T, 5juo:Y, 5jup:Y, 5jus:Y, 5jut:Y, 5juu:Y, 8k2d:LT, 8k82:LT, 5lyb:N1, 5lyb:n1, 5m1j:T5, 6m62:T, 5mc6:BJ, 5mei:2, 5mei:CV, 7mpi:AT, 7mpj:AT, 6n8j:T, 6n8k:T, 6n8l:T, 6n8m:g, 6n8n:g, 6n8o:g, 7n8b:AT, 7nac:T, 5ndg:N1, 5ndg:n1, 5ndv:N1, 5ndv:n1, 5ndw:N1, 5ndw:n1, 7nrc:LV, 7nrd:LV, 5obm:N1, 5obm:n1, 7of1:T, 7oh3:T, 7ohq:T, 7oht:T, 6oig:T, 5on6:2, 5on6:CV, 7osa:eL21, 7osm:eL21, 8p8m:QT, 8p8n:QT, 8p8u:QT, 8pfr:QT, 6q8y:BJ, 6qik:T, 6qt0:T, 6qtz:T, 7r7a:T, 6r84:V, 6r86:V, 6r87:V, 6ri5:T, 7rr5:LT, 6rzz:T, 6s05:T, 6s47:AV, 6snt:z, 6sv4:BJ, 6sv4:YJ, 6sv4:ZJ, 6t4q:LT, 5t62:g, 5t6r:g, 6t7i:LT, 6t7t:LT, 6t83:Ty, 6t83:E, 5tbw:2, 5tbw:CV, 6tb3:BJ, 5tga:N1, 5tga:n1, 5tgm:N1, 5tgm:n1, 6tnu:BJ, 7too:AL21, 7top:AL21, 4u3m:N1, 4u3m:n1, 4u3n:N1, 4u3n:n1, 4u3u:N1, 4u3u:n1, 4u4n:N1, 4u4n:n1, 4u4o:N1, 4u4o:n1, 4u4q:N1, 4u4q:n1, 4u4r:N1, 4u4r:n1, 4u4u:N1, 4u4u:n1, 4u4y:N1, 4u4y:n1, 4u4z:N1, 4u4z:n1, 4u50:N1, 4u50:n1, 4u51:N1, 4u51:n1, 4u52:N1, 4u52:n1, 4u53:N1, 4u53:n1, 4u55:N1, 4u55:n1, 4u56:N1, 4u56:n1, 4u6f:N1, 4u6f:n1, 7ug6:T, 7uoo:T, 7uqb:T, 7uqz:T, 6uz7:AT, 7v08:T, 4v4b:BQ, 4v6i:BU, 4v7f:T, 4v7h:BQ, 4v7r:BT, 4v7r:DT, 4v88:BT, 4v88:DT, 4v8t:T, 4v8y:BT, 4v8z:BT, 4v91:T, 6woo:T, 6xiq:T, 6xir:T, 8y0u:LT, 6ylg:T, 6ylh:T, 6ylx:T, 6yly:T, 7z34:T, 6z6j:LT, 6z6k:LT, 7zpq:BS, 7zrs:BS, 7zs5:BU, 7zuw:BS, 7zux:ES, 7zw0:LW
10 7olc:LT 158 150 0.4430 0.4430 0.4667 1.33e-40 8i9p:LT, 8i9r:LT, 8i9t:LT, 8i9v:LT, 8i9w:LT, 8i9x:LT, 8i9y:LT, 8i9z:LT, 8ia0:LT, 7old:LT, 8oo0:LT, 8pv1:LT, 8pv2:LT, 8pv3:LT, 8pv4:LT, 8pv5:LT, 8pv6:LT, 8pv7:LT, 8pv8:LT, 8pvk:LT, 8pvl:LT, 7z3n:LT, 7z3o:LT
11 4v3p:LU 164 141 0.3987 0.3841 0.4468 1.55e-37 8ip8:BA, 8ipa:BA, 8ipb:BA, 8jiv:CT, 4v7e:CT
12 3j79:V 155 140 0.4177 0.4258 0.4714 6.19e-37 3jbn:AV, 3jbo:AV, 3jbp:AV, 8tpu:AV, 5umd:V
13 7cpu:LT 160 150 0.4114 0.4062 0.4333 3.95e-35 7a01:72, 8a3d:N, 5aj0:AT, 8b5l:T, 8b6c:T, 9bdl:AL21, 9bdn:AL21, 9bdp:AL21, 7bhp:LT, 8bhf:G1, 8bpo:S2, 8btk:BT, 7cpv:LT, 4d5y:T, 4d67:T, 6d90:T, 6d9j:T, 9f1b:BT, 9f1c:BT, 9f1d:BT, 7f5s:LT, 8fkp:LE, 8fkq:LE, 8fkr:LE, 8fks:LE, 8fkt:LE, 8fku:LE, 8fkv:LE, 8fkw:LE, 8fkx:LE, 8fky:LE, 8fkz:LE, 8fl0:LE, 8fl2:LE, 8fl3:LE, 8fl4:LE, 8fl6:LE, 8fl7:LE, 8fl9:LE, 8fla:LE, 8flb:LE, 8flc:LE, 8fld:LE, 8fle:LE, 8flf:LE, 6frk:T, 6ftg:T, 6fti:T, 6ftj:T, 8g5y:LT, 8g5z:LT, 8g60:LT, 8g61:LT, 8g6j:LT, 8glp:LT, 6gz3:AT, 6gz4:AT, 6gz5:AT, 6hcf:T3, 6hcj:T3, 6hcm:T3, 6hcq:T3, 8idt:c, 8idy:c, 8ie3:c, 8ifd:2N, 8ife:2N, 8ine:c, 8inf:c, 8ink:T, 6ip5:2N, 6ip6:2N, 6ip8:2N, 8ipd:T, 8ipx:T, 8ipy:T, 8ir1:c, 8ir3:c, 3j7o:T, 3j7p:T, 3j7q:T, 3j7r:T, 3j92:T, 3jag:T, 3jah:T, 3jai:T, 3jaj:T, 3jan:T, 8jdj:Y, 8jdk:Y, 8jdl:Y, 8jdm:Y, 8k2c:LT, 5lks:LT, 6lqm:c, 6lsr:c, 6lss:c, 7ls1:N2, 7ls2:N2, 6lu8:c, 5lzs:T, 5lzt:T, 5lzu:T, 5lzv:T, 5lzw:T, 5lzx:T, 5lzy:T, 5lzz:T, 7mdz:T, 6mtb:T, 6mtc:T, 6mtd:T, 6mte:T, 7nfx:T, 7nwg:T3, 7nwh:T, 7nwi:T, 7o7y:BT, 7o7z:BT, 7o80:BT, 7o81:BT, 7obr:T, 8ohd:LT, 8oj0:LT, 8oj5:LT, 8oj8:LT, 6ole:U, 6olf:U, 6olg:AT, 6oli:U, 6olz:AT, 6om0:U, 6om7:U, 7ow7:N, 7oyd:T, 8p2k:BT, 6p5i:AT, 6p5j:AT, 6p5k:AT, 6p5n:AT, 8q7z:BT, 8q87:BT, 8qfd:T, 7qgg:U, 8qoi:LT, 7qvp:LT, 7qvp:MT, 7qwq:T, 7qwr:T, 7qws:T, 6qzp:LT, 6r5q:T, 6r6g:T, 6r6p:T, 6r7q:T, 8rjb:T, 8rjc:T, 8rjd:T, 8scb:T, 6sgc:T2, 6swa:R, 5t2c:N, 6t59:T3, 7tm3:T, 7toq:AL21, 7tor:AL21, 7tut:T, 7ucj:T, 7uck:T, 4ug0:LT, 4ujc:BT, 4ujd:AT, 4uje:CT, 4v5z:Bq, 4v6x:CT, 6w6l:U, 6xa1:LT, 7xnx:LT, 7xny:LT, 8xsx:LT, 8xsy:LT, 8xsz:LT, 6y0g:LT, 8y0w:LT, 8y0x:LT, 6y2l:LT, 6y57:LT, 6y6x:LT, 8yoo:LT, 8yop:LT, 6z6l:LT, 6z6m:LT, 6z6n:LT, 7zjw:LW, 7zjx:LW, 6zm7:LT, 6zme:LT, 6zmi:LT, 6zmo:LT, 6zvk:72
14 6rm3:LT0 159 155 0.3987 0.3962 0.4065 9.87e-35
15 7r81:V1 159 141 0.3734 0.3711 0.4184 3.55e-34
16 8br8:LU 157 142 0.3671 0.3694 0.4085 6.30e-34 8brm:LU, 8bsi:LU, 8bsj:LU, 8btd:LU, 8btr:LU, 8fru:T, 7pwg:T, 7pwo:T2
17 8c3a:2 159 138 0.3797 0.3774 0.4348 6.39e-34 8c3a:BO, 8cq7:2, 8cq7:BO, 8cqw:2, 8cqw:BO, 8cre:2, 8cre:BO, 8oeq:2, 8oeq:BO, 7pzy:2, 7q08:2, 7q0f:2, 7q0p:2, 7q0r:2, 8q5i:2
18 7oyc:T1 157 137 0.3924 0.3949 0.4526 1.16e-33
19 6zu5:LT0 160 159 0.3987 0.3937 0.3962 1.25e-33
20 9bh5:CT 160 135 0.3734 0.3688 0.4370 3.13e-33 9cai:CT
21 5xy3:T 158 141 0.3797 0.3797 0.4255 4.14e-32
22 7oya:T1 157 150 0.3861 0.3885 0.4067 6.85e-32 7oyb:T1
23 7qep:N1 159 155 0.3924 0.3899 0.4000 3.72e-31
24 4v8p:BP 156 136 0.3418 0.3462 0.3971 7.39e-31 4v8p:CP, 4v8p:EP, 4v8p:GP
25 8p5d:LT0 156 134 0.3418 0.3462 0.4030 1.50e-30 8p60:LT0, 8p60:KT0, 7qca:LT0
26 6skf:BU 96 62 0.1709 0.2812 0.4355 6.83e-08 6skg:BU, 6th6:BU, 4v4n:AR, 4v6u:BR
27 8hku:L21E 97 94 0.2089 0.3402 0.3511 8.16e-08 8hkv:L21E, 8hky:L21E, 8hkz:L21E, 8hl1:L21E, 8hl2:L21E, 8hl3:L21E, 8hl4:L21E, 8hl5:L21E
28 7u0h:T 57 21 0.0633 0.1754 0.4762 0.40
29 2v6e:A 531 35 0.0759 0.0226 0.3429 1.5 2v6e:B
30 3cc2:Q 95 63 0.1329 0.2211 0.3333 1.6 3cc4:Q, 3cc7:Q, 3cce:Q, 3ccj:Q, 3ccl:Q, 3ccm:Q, 3ccq:Q, 3ccr:Q, 3ccs:Q, 3ccu:Q, 3ccv:Q, 3cd6:Q, 3cma:Q, 3cme:Q, 3cpw:P, 3cxc:P, 1ffk:N, 3g4s:Q, 3g6e:Q, 3g71:Q, 3i55:Q, 3i56:Q, 1jj2:P, 1k73:R, 1k8a:R, 1k9m:R, 1kc8:R, 1kd1:R, 1kqs:P, 1m1k:R, 1m90:R, 1n8r:R, 1nji:R, 2otj:Q, 2otl:Q, 3ow2:P, 1q7y:R, 1q81:R, 1q82:R, 1q86:R, 2qa4:Q, 2qex:Q, 1qvf:P, 1qvg:P, 1s72:Q, 4v9f:Q, 1vq4:Q, 1vq5:Q, 1vq6:Q, 1vq7:Q, 1vq8:Q, 1vq9:Q, 1vqk:Q, 1vql:Q, 1vqm:Q, 1vqn:Q, 1vqo:Q, 1vqp:Q, 1w2b:P, 1yhq:Q, 1yi2:Q, 1yij:Q, 1yit:Q, 1yj9:Q, 1yjn:Q, 1yjw:Q
31 5dis:C 264 28 0.0696 0.0417 0.3929 2.3 1xk5:A
32 7obb:B 1130 31 0.0696 0.0097 0.3548 2.6 7ob9:B, 7oba:B, 7vba:B, 7vbb:B, 7vbc:B
33 3h4l:B 344 28 0.0696 0.0320 0.3929 9.1 3h4l:A
34 8wgo:A 869 38 0.0823 0.0150 0.3421 9.9 8w7j:A, 8wgo:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218