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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PHSHPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFH
ETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSA
LAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACT
QKYSHEEIAMATVTALRRTVPPAVTGVTFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENL
KAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFISNHAY

The query sequence (length=363) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4ald:A 363 363 0.9835 0.9835 0.9835 0.0 6ald:A, 6ald:B, 3dft:A, 3dft:B, 3dft:C, 3dft:D, 3lge:A, 3lge:B, 3lge:C, 3lge:D, 2ot0:A, 2ot0:B, 2ot0:C, 2ot0:D, 2ot1:A, 2ot1:B, 2ot1:C, 2ot1:D, 2quv:A, 2quv:B, 2quv:D, 5tle:A, 5tle:B, 5tle:C, 5tle:D, 5tlh:A, 5tlh:B, 5tlh:C, 5tlh:D, 5tlw:A, 5tlw:B, 5tlw:C, 5tlw:D, 5tlz:A, 5tlz:B, 5tlz:C, 5tlz:D, 3tu9:A, 3tu9:B, 3tu9:C, 3tu9:D, 6xmh:A, 6xmh:B, 6xml:A, 6xml:B, 6xmm:A, 6xmm:B, 6xmo:A, 6xmo:B, 1zai:A, 1zai:B, 1zai:C, 1zai:D, 1zaj:A, 1zaj:B, 1zaj:C, 1zaj:D, 1zal:A, 1zal:B, 1zal:C, 1zal:D
2 1fdj:A 363 362 0.7080 0.7080 0.7099 0.0 1fdj:B
3 6rng:B 334 329 0.5895 0.6407 0.6505 3.79e-146 6rng:G
4 5tkl:A 350 339 0.5537 0.5743 0.5929 3.00e-130 5tk3:A, 5tkc:A, 5tkn:A, 5tkp:A
5 2eph:D 351 345 0.5344 0.5527 0.5623 5.91e-123 2pc4:D, 4tr9:A, 4tr9:B, 4tr9:C, 4tr9:D
6 3mmt:A 341 335 0.4904 0.5220 0.5313 5.60e-113 3mmt:B, 3mmt:C, 3mmt:D
7 2qdg:A 366 332 0.4628 0.4590 0.5060 3.53e-105 2qap:A, 2qap:B, 2qap:C, 2qap:D, 2qdg:B, 2qdg:C, 2qdg:D, 2qdh:A, 2qdh:B, 2qdh:C, 2qdh:D
8 3mbf:A 337 322 0.3526 0.3798 0.3975 3.62e-79 3mbd:A, 3qrh:A
9 6zga:A 751 96 0.0826 0.0399 0.3125 0.40 4bzi:A, 4bzi:D, 4bzi:G, 6gni:A, 1m2o:A, 1m2o:C, 2qtv:A, 6zga:E
10 6bq1:E 1510 35 0.0413 0.0099 0.4286 2.5 6bq1:A
11 7sqm:A 346 86 0.0689 0.0723 0.2907 2.7 7avq:A, 3dlz:A, 3e7v:A, 3f2n:A, 9flb:A, 9flc:A, 9flo:A, 9flq:A, 9flt:A, 3fmd:A, 6g34:A, 6g35:A, 6g36:A, 6g37:A, 6g38:A, 6g39:A, 6g3a:A, 5htb:A, 5htc:A, 3iq7:A, 7ops:A, 4ouc:A, 4qtc:A, 8rdk:A, 2vuw:A, 6z56:A, 6z57:A, 6z58:A, 6z59:A, 6z5a:A, 6z5b:A, 6z5c:A, 6z5d:A, 6z5e:A
12 7ne2:D 292 55 0.0413 0.0514 0.2727 3.0 7ne2:A, 7ne2:B, 7ne2:C
13 6e4v:A 672 39 0.0303 0.0164 0.2821 4.1
14 7tau:A 951 31 0.0331 0.0126 0.3871 5.1 7tau:C, 7tau:D, 7tau:E, 7tau:F, 7tau:H, 7tau:I, 7tau:G, 7tau:K, 7tau:L, 7tau:J, 5tx1:A, 5tx1:C, 5tx1:D, 5tx1:E, 5tx1:F, 5tx1:H, 5tx1:I, 5tx1:G, 5tx1:J, 5tx1:L
15 5f1a:A 553 122 0.0909 0.0597 0.2705 6.4 5f19:A, 5f19:B, 5f1a:B, 5ikq:A, 5ikq:B, 5ikr:A, 5ikr:B, 5ikt:A, 5ikt:B, 5ikv:A, 5ikv:B, 5kir:A, 5kir:B
16 7kp8:A 140 33 0.0358 0.0929 0.3939 8.8 7kp8:B, 7kp8:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218