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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
PHMKHPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGR
WVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNS
LQYQLHKDTMVKQNVKSIYTL

The query sequence (length=181) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5t48:A 181 181 1.0000 1.0000 1.0000 3.01e-135 5abu:A, 4axg:B, 4uec:A, 4uec:C
2 5ei3:A 191 173 0.5138 0.4869 0.5376 9.45e-65 3am7:A, 4aza:A, 4aza:C, 4bea:A, 5bxv:A, 5bxv:C, 7d6y:A, 4dt6:A, 4dum:A, 5ehc:A, 5eir:A, 1ej1:A, 1ej1:B, 1ej4:A, 1ejh:A, 1ejh:B, 1ejh:C, 1ejh:D, 5ekv:A, 5ekv:C, 7ezw:A, 6gkj:A, 6gkj:B, 6gkj:C, 6gkj:D, 6gkk:A, 6gkk:B, 6gkk:C, 6gkk:D, 6gkl:A, 6gkl:B, 6gkl:C, 6gkl:D, 1ipb:A, 1ipc:A, 5j5o:A, 5j5o:B, 5j5o:C, 5j5o:D, 5j5y:A, 5j5y:B, 1l8b:A, 1l8b:B, 5m7v:A, 5m7v:B, 5m7v:C, 5m7w:A, 5m7w:B, 5m7w:C, 5m7w:D, 5m7x:A, 5m7x:B, 5m7x:C, 5m7x:D, 5m7z:A, 5m7z:B, 5m7z:C, 5m80:A, 5m80:B, 5m81:A, 5m81:B, 5m81:C, 5m81:D, 5m83:A, 5m83:B, 5m84:A, 5m84:B, 7meu:A, 7meu:B, 5osx:A, 5osx:B, 8sx4:A, 8sx4:B, 5t46:A, 5t46:C, 4tpw:A, 4tpw:B, 4tqb:A, 4tqb:B, 4tqc:A, 4tqc:B, 6u06:A, 6u06:B, 6u06:C, 6u06:D, 6u09:A, 6u09:B, 6u09:C, 6u09:D, 3u7x:A, 3u7x:B, 2v8w:A, 2v8w:E, 2v8x:A, 2v8x:E, 2v8y:A, 2v8y:E, 2w97:A, 2w97:B, 1wkw:A, 7xtp:A, 7xtp:B, 6ylr:A, 6ylr:B, 6ylt:A, 6ylt:B, 6ylt:C, 6ylt:D, 6ylv:A, 6ylv:B, 6ylv:C, 6ylv:D, 5zjy:A, 5zjz:A, 5zk5:A, 5zk7:A, 5zk7:B, 5zk9:A, 5zml:A
3 3m93:A 180 175 0.4586 0.4611 0.4743 6.51e-59 3m94:A
4 5abx:A 173 173 0.4530 0.4740 0.4740 3.98e-58
5 1ap8:A 213 179 0.4088 0.3474 0.4134 8.47e-44 6fc1:A, 6fc1:C, 1rf8:A
6 2wmc:A 174 180 0.3867 0.4023 0.3889 2.51e-43 2wmc:B, 2wmc:C, 2wmc:D, 2wmc:E, 2wmc:F, 2wmc:G, 2wmc:H
7 2idv:A 177 169 0.3757 0.3842 0.4024 5.31e-43
8 6fbz:A 191 172 0.3370 0.3194 0.3547 6.53e-40
9 5me6:A 175 168 0.3757 0.3886 0.4048 8.24e-39 5me6:D
10 3hxg:A 183 182 0.3481 0.3443 0.3462 8.21e-38 3hxi:A
11 2jgb:A 187 172 0.3425 0.3316 0.3605 1.60e-37 2jgc:A, 5xln:A
12 4b6u:A 207 153 0.2541 0.2222 0.3007 1.44e-19
13 6o7y:A 183 154 0.1878 0.1858 0.2208 0.017 6o7z:A, 6o80:A
14 1nj1:A 463 24 0.0608 0.0238 0.4583 2.2 1nj2:A, 1nj5:A, 1nj6:A
15 6hnd:B 470 42 0.0773 0.0298 0.3333 4.4 6hnd:A, 6hnv:A, 6hnv:B
16 5isx:A 529 115 0.1492 0.0510 0.2348 8.5 5isx:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218